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Pergolide

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: N04BC02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Abdominal pain Abdominal pain frequent, 5.8% 2.1% x x
Gastrointestinal pain Abdominal pain frequent, 5.8% 2.1% x x
Amnesia Amnesia frequent x x
Anaemia Anaemia frequent, 1.1% 1% x x
Anxiety Anxiety frequent, 6.4% 4.3% x x
Arthralgia Arthralgia frequent, 1.6% 2.1% x x
Musculoskeletal discomfort Arthralgia frequent, 1.6% 2.1% x x
Myalgia frequent, 1.1% 1% x x
Asthenia Asthenia frequent, 4.2% 4.8% x x
Back pain Back pain frequent, 1.6% 2.1% x x
Neck pain Neck pain frequent, 2.7% 1.6% x x
Chest pain Chest pain frequent, 3.7% 2.1% x x
Constipation Constipation frequent, 10.6% 5.9% x x
Dysphagia Dysphagia frequent x x
Diarrhoea Diarrhoea frequent, 6.4% 2.7% x x
Diplopia Diplopia frequent, 2.1% 0% x x
Dizziness Dizziness frequent, 19.1% 13.9% x x
Syncope frequent, 2.1% 1.1% x x
Dyskinesia Dyskinesia frequent, 62.4% 24.6% x x
Dysmenorrhoea Dysmenorrhoea frequent x x
Dyspepsia Dyspepsia frequent, 6.4% 2.1% x x
Dyspnoea Dyspnoea frequent, 4.8% 1.1% x x
Dermatitis Rash frequent, 3.2% 2.1% x x
Rash Rash frequent, 3.2% 2.1% x x
Extrapyramidal disorder Extrapyramidal disorder frequent, 1.6% 1.1% x x
Body temperature increased Body temperature increased frequent x x
Hallucination Hallucination rare — 7.8% - 13.8% 3.2% x x
Headache Headache frequent, 5.3% 6.4% x x
Cardiac failure congestive Cardiac failure congestive frequent x x
Haematuria Haematuria frequent, 1.1% 1% x x
Hypertension Hypertension frequent, 1.6% 1.1% x x
Orthostatic hypotension Orthostatic hypotension frequent, 9% 7% x x
Influenza Influenza frequent, 3.2% 2.1% x x
Nausea Nausea infrequent — 24.3% 12.8% x x
Nervousness Nervousness frequent x x
Tension Nervousness frequent x x
Pain Pain frequent, 7% 2.1% x x
Palpitations Palpitations frequent, 2.1% 1% x x
Paraesthesia Paraesthesia frequent, 1.6% 3.2% x x
Personality disorder Personality disorder frequent, 2.1% 1% x x
Pharyngitis Pharyngitis frequent x x
Pneumonia Pneumonia frequent x x
Psychotic disorder Psychotic disorder frequent, 2.1% 0% x x
Rhinitis Rhinitis frequent, 12.2% 5.4% x x
Hyperhidrosis Sweating frequent, 2.1% 2.7% x x
Shock Syncope frequent, 2.1% 1.1% x x
Shock infrequent x x
Syncope Syncope frequent, 2.1% 1.1% x x
Loss of consciousness Syncope frequent, 2.1% 1.1% x x
Tremor Tremor frequent, 4.2% 7.5% x x
Pollakiuria Pollakiuria frequent, 2.7% 6.4% x x
Urinary incontinence Urinary incontinence frequent x x
Urinary tract infection Urinary tract infection frequent, 2.7% 3.7% x x
Weight increased Weight increased frequent, 1.6% 0% x x
Weight decreased Weight decreased frequent x x
Dry mouth Dry mouth frequent, 3.7% 1% x x
Choreoathetosis Choreoathetosis frequent x x
Akinesia Akinesia frequent, 1.1% 1.1% x x
Oedema peripheral Oedema peripheral frequent, 7.4% 4.3% x x
Injury Accidental injury frequent x x
Paranoia Paranoid reaction frequent x x
Myalgia Myalgia frequent, 1.1% 1% x x
Muscle twitching Muscle twitching frequent, 1.1% 0% x x
Thinking abnormal Thinking abnormal frequent x x
Mental disability Thinking abnormal frequent x x
Abnormal dreams Abnormal dreams frequent, 2.7% 4.3% x x
Coordination abnormal Coordination abnormal frequent, 1.6% 1% x x
Cough Cough increased frequent x x
Gait disturbance Gait disturbance frequent, 1.6% 1.6% x x
Insomnia Insomnia frequent, 7.9% 3.2% x x
Somnolence Somnolence frequent, 10.1% 3.7% x x
Visual impairment Abnormal vision frequent, 5.8% 5.4% x x
Decreased appetite Anorexia 4.8% 2.7% x x
Depression Depression 3.2% 5.4% x x
Vomiting Vomiting infrequent, frequent x x
Hypotension Hypotension 2.1% 1% x x
Confusional state Confusional state rare — 1.8% - 11.1% 9.6% x x
Feeling abnormal Confusional state rare — 1.8% - 11.1% 9.6% x x
Malaise infrequent x x
Bursitis Bursitis 1.6% 1% x x
Oedema Oedema 1.6% 0% x x
Arrhythmia Arrhythmia 1.1% 1% x x
Infection Infection 1.1% 0% x x
Eye disorder Eye disorder 1.1% 0% x x
Speech disorder Speech disorder 1.1% 1.6% x x
Abscess Abscess infrequent x x
Adenoma benign Adenoma benign infrequent x x
Alopecia Alopecia infrequent x x
Anaemia megaloblastic Anaemia megaloblastic infrequent x x
Angina pectoris Angina pectoris infrequent x x
Apnoea Apnoea infrequent x x
Arthritis Arthritis infrequent x x
Asthma Asthma infrequent x x
Ataxia Ataxia infrequent x x
Atrial fibrillation Atrial fibrillation infrequent x x
Atrioventricular block Atrioventricular block infrequent x x
Block heart rare x x
Bronchitis Bronchitis infrequent x x
Candida infection Candida infection infrequent x x
Cellulitis Cellulitis infrequent x x
Cholelithiasis Cholelithiasis infrequent x x
Coma Coma infrequent x x
Conjunctivitis Conjunctivitis infrequent x x
Cyanosis Cyanosis infrequent x x
Cystitis Cystitis infrequent x x
Bladder pain Cystitis infrequent x x
Cystitis noninfective Cystitis infrequent x x
Deafness Deafness infrequent x x
Libido decreased Libido decreased infrequent x x
Disturbance in sexual arousal Libido decreased infrequent x x
Libido increased infrequent x x
Dehydration Dehydration infrequent x x
Delirium Delirium infrequent x x
Delusion Delusion infrequent x x
Dental caries Dental caries infrequent x x
Fungal skin infection Fungal skin infection infrequent x x
Diabetes mellitus Diabetes mellitus infrequent x x
Dysgeusia Dysgeusia infrequent, 1.6% 0% x x
Dysuria Dysuria infrequent x x
Ear pain Ear pain infrequent x x
Eczema Eczema infrequent x x
Epistaxis Epistaxis infrequent, 1.6% 1% x x
Eructation Eructation infrequent x x
Oesophagitis Oesophagitis infrequent x x
Eye haemorrhage Eye haemorrhage infrequent x x
Fibrocystic breast disease Fibrocystic breast disease infrequent x x
Flatulence Flatulence infrequent x x
Gastritis Gastritis infrequent x x
Gastroenteritis Gastroenteritis infrequent x x
Gingivitis Gingivitis infrequent x x
Glaucoma Glaucoma infrequent x x
Gout Gout infrequent x x
Cardiac arrest Cardiac arrest infrequent x x
Haematemesis Haematemesis infrequent x x
Haemoptysis Haemoptysis infrequent x x
Hepatitis Hepatitis infrequent x x
Hepatomegaly Hepatomegaly infrequent x x
Hernia Hernia infrequent x x
Herpes simplex Herpes simplex infrequent x x
Herpes zoster Herpes zoster infrequent x x
Hiccups Hiccups infrequent, 1.1% 0% x x
Hirsutism Hirsutism infrequent x x
Hostility Hostility infrequent x x
Hypercholesterolaemia Hypercholesterolaemia infrequent x x
Hyperglycaemia Hyperglycaemia infrequent x x
Salivary gland enlargement Salivary gland enlargement infrequent x x
Hyperventilation Hyperventilation infrequent x x
Hypoglycaemia Hypoglycaemia infrequent x x
Hypokalaemia Hypokalaemia infrequent x x
Body temperature decreased Body temperature decreased infrequent x x
Hypothermia Body temperature decreased infrequent x x
Hypothyroidism Hypothyroidism infrequent x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion infrequent x x
Libido increased Libido increased infrequent x x
Intestinal obstruction Intestinal obstruction infrequent x x
Nephrolithiasis Calculus of kidney infrequent x x
Laryngitis Laryngitis infrequent x x
Leukocytosis Leukocytosis infrequent x x
Leukopenia Leukopenia infrequent x x
Breast pain Breast pain infrequent x x
Melaena Melaena infrequent x x
Meningitis Meningitis infrequent x x
Menopause Menopause infrequent x x
Menorrhagia Menorrhagia infrequent x x
Metrorrhagia Metrorrhagia infrequent x x
Hypertonia Hypertonia infrequent, 1.1% 0% x x
Hypotonia Hypotonia infrequent x x
Muscle relaxant therapy Hypotonia infrequent x x
Myocardial infarction Myocardial infarction infrequent, 1.1% 1% x x
Acute coronary syndrome Myocardial infarction infrequent, 1.1% 1% x x
Myoclonus Myoclonus infrequent x x
Myositis Myositis infrequent x x
Neoplasm Neoplasm infrequent x x
Neuralgia Neuralgia infrequent, 1.1% 1% x x
Neurosis Neurosis infrequent x x
Otitis media Otitis media infrequent x x
Pelvic pain Pelvic pain infrequent x x
Tooth abscess Abscess periodontal infrequent x x
Petechiae Petechiae infrequent x x
Pleural effusion Pleural effusion infrequent x x
Priapism Priapism infrequent x x
Pruritus Pruritus infrequent x x
Pulmonary oedema Pulmonary oedema infrequent x x
Pulmonary embolism Pulmonary embolism infrequent x x
Emphysema Emphysema infrequent x x
Pyuria Pyuria infrequent x x
Renal failure Renal failure infrequent x x
Salpingitis Salpingitis infrequent x x
Scotoma Scotoma infrequent x x
Seborrhoeic dermatitis Seborrhoeic dermatitis infrequent x x
Convulsion Convulsion infrequent x x
Sinusitis Sinusitis infrequent x x
Skin ulcer Skin ulcer infrequent x x
Gastric ulcer Gastric ulcer infrequent x x
Cerebrovascular accident Cerebrovascular accident infrequent x x
Tachycardia Tachycardia infrequent x x
Tenosynovitis Tenosynovitis infrequent x x
Thirst Thirst infrequent x x
Thrombocytopenia Thrombocytopenia infrequent x x
Thrombophlebitis Thrombophlebitis infrequent x x
Tinnitus Tinnitus infrequent x x
Torticollis Torticollis infrequent x x
Uterine haemorrhage Uterine haemorrhage infrequent x x
Vaginal inflammation Vaginal inflammation infrequent x x
Vaginal infection Vaginal inflammation infrequent x x
Varicose vein Varicose vein infrequent x x
Ventricular tachycardia Ventricular tachycardia infrequent x x
Vertigo Vertigo infrequent x x
Urinary retention Urinary retention infrequent x x
Chills Chills infrequent, 1.1% 0% x x
Agitation Agitation infrequent x x
Hyperkinesia infrequent x x
Apathy Apathy infrequent x x
Flat affect Apathy infrequent x x
Mood swings Mood swings infrequent x x
Affect lability Mood swings infrequent x x
Photophobia Photophobia infrequent x x
Hypokinesia Hypokinesia infrequent x x
Ventricular extrasystoles Ventricular extrasystoles infrequent x x
Liver function test abnormal Liver function test abnormal infrequent x x
Mania Manic psychosis infrequent x x
Bone pain Bone pain infrequent x x
Eye pain Eye pain infrequent x x
Skin discolouration Skin discolouration infrequent x x
Dry skin Dry skin infrequent x x
Iron deficiency anaemia Iron deficiency anaemia infrequent x x
Malaise Malaise infrequent x x
Discomfort Malaise infrequent x x
Ill-defined disorder Malaise infrequent x x
Increased appetite Increased appetite infrequent x x
Euphoric mood Euphoric mood infrequent x x
Pain in jaw Pain in jaw infrequent x x
Erectile dysfunction Erectile dysfunction infrequent x x
Sepsis Sepsis infrequent x x
Cervix carcinoma Cervix carcinoma infrequent x x
Abdominal distension Enlargement abdomen infrequent x x
Akathisia Akathisia infrequent, 1.6% 0% x x
Hyperkinesia Hyperkinesia infrequent x x
Bradycardia Bradycardia infrequent x x
Neuropathy peripheral Neuropathy infrequent x x
Neuritis rare x x
Calculus urinary Urolithiasis infrequent x x
Lymphadenopathy Lymphadenopathy infrequent x x
Electrocardiogram abnormal Electrocardiogram abnormal infrequent x x
Paralysis Paralysis infrequent x x
Face oedema Face oedema infrequent, 1.1% 0% x x
Breast cancer Carcinoma breast infrequent x x
Skin cancer Skin carcinoma infrequent x x
Cerebral ischaemia Cerebral ischaemia infrequent x x
Bone sarcoma Bone sarcoma infrequent x x
Vaginal haemorrhage Vaginal haemorrhage infrequent x x
Acute abdomen Acute abdomen rare x x
Acidosis Acidosis rare x x
Amenorrhoea Amenorrhoea rare x x
Benign neoplasm of skin Benign neoplasm of skin rare x x
Cachexia Cachexia rare x x
Cholecystitis Cholecystitis rare x x
Colitis Colitis rare x x
Duodenitis Duodenitis rare x x
Endocrine disorder Endocrine disorder rare x x
Eosinophilia Eosinophilia rare x x
Epididymitis Epididymitis rare x x
VIIth nerve paralysis Facial paralysis rare x x
Faecal incontinence Faecal incontinence rare x x
Glossitis Glossitis rare x x
Hemiplegia Hemiplegia rare x x
Haemothorax Haemothorax rare x x
Pulmonary hypertension Pulmonary hypertension rare x x
Hypogonadism Hypogonadism rare x x
Jaundice Jaundice rare x x
Laryngeal oedema Laryngeal oedema rare x x
Acute lymphocytic leukaemia Acute lymphocytic leukaemia rare x x
Vaginal discharge Leukorrhea rare x x
Systemic lupus erythematosus Systemic lupus erythematosus rare x x
Lymphocytosis Lymphocytosis rare x x
Muscle atrophy Muscle atrophy rare x x
Myelitis Myelitis rare x x
Nephrotic syndrome Nephrosis rare x x
Neuritis Neuritis rare x x
Osteomyelitis Osteomyelitis rare x x
Osteoporosis Osteoporosis rare x x
Pancreatitis Pancreatitis rare x x
Peptic ulcer Peptic ulcer rare x x
Pericarditis Pericarditis rare x x
Pneumothorax Pneumothorax rare x x
Polycythaemia Polycythaemia rare x x
Pulmonary fibrosis Pulmonary fibrosis rare x x
Purpura Purpura rare x x
Vascular purpura Purpura rare x x
Pyelonephritis Pyelonephritis rare x x
Retinal detachment Retinal detachment rare x x
Sialoadenitis Sialoadenitis rare x x
Skin mass Skin nodule rare x x
Subcutaneous nodule rare x x
Splenomegaly Splenomegaly rare x x
Aphthous stomatitis Aphthous stomatitis rare x x
Vasculitis Vasculitis rare x x
Stupor Stupor rare x x
Depressed level of consciousness Stupor rare x x
Breast engorgement Breast engorgement rare x x
Cataract Cataract rare x x
Migraine Migraine rare x x
Thyroid adenoma Thyroid adenoma rare x x
Intracranial pressure increased Intracranial pressure increased rare x x
Urethral pain Urethral pain rare x x
Rash pustular Vesiculobullous rash rare x x
Dermatitis bullous Vesiculobullous rash rare x x
Oesophageal ulcer Oesophageal ulcer rare x x
Withdrawal bleed Withdrawal bleed rare x x
Retinal vascular disorder Retinal vascular disorder rare x x
Lichenoid keratosis Eruption lichenoid rare x x
Hyperuricosuria Uricaciduria rare x x
Electrolyte imbalance Electrolyte imbalance rare x x
Blindness Blindness rare x x
Lung neoplasm malignant Carcinoma of lung rare x x
Bladder cancer Bladder carcinoma rare x x
Blood uric acid increased Hyperuricaemia rare x x
Hyperuricaemia Hyperuricaemia rare x x
Thrombocytosis Thrombocytosis rare x x
Brain oedema Brain oedema rare x x
Cerebral haemorrhage Cerebral haemorrhage rare x x
Hypoxia Hypoventilation rare x x
Respiratory failure Hypoventilation rare x x
Hypoventilation Hypoventilation rare x x
Neuroleptic malignant syndrome Neuroleptic malignant syndrome x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

pergolide

Side effects:294
Source:FDA Structured Product Label

PERGOLIDE MESYLATE / PERMAX

Side effects:294
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label