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Palonosetron

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: A04AA05

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Headache Headache 3.27% - 16.5% 3.79% x x x x x x
Constipation Constipation 1.95% - 6.19% 2.98% x x x x x x
Bradycardia Bradycardia 3.87% 4.34% x x x x x
Dizziness Dizziness 1.26% - 2.2% x x x x x
Diarrhoea Diarrhoea 1.26% - 2.06% x x x x x
Asthenia Fatigue 0.474% - 2.06% x x x x x x
Asthenia x x x x x
Fatigue Fatigue 0.474% - 2.06% x x x x x x
Insomnia Insomnia 0.158% - 1.55% x x x x x x
Abdominal pain Abdominal pain 0.158% - 1.55% x x x x x
Gastrointestinal pain Abdominal pain 0.158% - 1.55% x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x
Anaphylactoid reaction x
Hypersensitivity Hypersensitivity postmarketing x x x x x
Nausea Nausea postmarketing x x
Pain Pain postmarketing x x x x
Vomiting Vomiting postmarketing x x
Injection site reaction Injection site reaction postmarketing x x x x
Discomfort Discomfort postmarketing x x x x
Induration Induration postmarketing x x x x
Alopecia Alopecia x
Amblyopia Amblyopia x x x x x
Anaemia Anaemia x
Decreased appetite Anorexia x x x x x x
Decreased appetite x x x x x
Anxiety Anxiety x x x x x
Arrhythmia Arrhythmia x x x
Sinus arrhythmia Sinus arrhythmia x x x x x
Arthralgia Arthralgia x x x x x
Musculoskeletal discomfort Arthralgia x x x x x
Myalgia x
Mental disorder Mental disorder x
Infection Infection x
Connective tissue disorder Connective tissue disorder x
Cyanosis Cyanosis x x
Dermatitis atopic Dermatitis atopic x x x x x
Abdominal distension Distention x x x x
Dysgeusia Dysgeusia x
Dyskinesia Dyskinesia x
Dyspepsia Dyspepsia x x x x x
Dyspnoea Dyspnoea x
Gasping x x
Epistaxis Epistaxis x
Dermatitis Rash x x x x
Rash Rash x x x x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x x x x x x
Flatulence Flatulence x x x x x
Gastritis Gastritis x
Gastrointestinal disorder Gastrointestinal disorder x
Glycosuria Glycosuria x x x x x
Cardiac disorder Cardiac disorder x
Hiccups Hiccups x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hyperglycaemia Hyperglycaemia x x x x x
Hyperkalaemia Hyperkalaemia x x x x x
Hypertension Hypertension x x x x x x
Hypocalcaemia Hypocalcaemia x
Hypokalaemia Hypokalaemia x x x
Hypotension Hypotension x x x x x
Immune system disorder Immune system disorder x
Laryngospasm Laryngospasm x x
Mediastinal disorder Mediastinal disorder x
Metabolic disorder Metabolic disorder x
Motion sickness Motion sickness x x x x x x
Nervous system disorder Nervous system disorder x
Pain in extremity Pain in extremity x
Pallor Pallor x x
Paraesthesia Paraesthesia x x x x x
Supraventricular extrasystoles Supraventricular extrasystoles x x x x x
Prurigo Prurigo x
Pruritus Pruritus x x
Convulsion Convulsion x x
Shock Shock x
Salivary hypersecretion Salivary hypersecretion x x
Sinusitis Sinusitis x
Skin disorder Skin disorder x
Unspecified disorder of skin and subcutaneous tissue x
Tachycardia Tachycardia x x x x x
Sinus tachycardia Sinus tachycardia x x x x x
Tinnitus Tinnitus x x x x x
Erythema Erythema x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x
Dry mouth Dry mouth x x x x x
Urinary retention Urinary retention x x x x x
Chills Chills x x x
Sinus bradycardia Sinus bradycardia x x
Atrioventricular block first degree Atrioventricular block first degree x
Peripheral sensory neuropathy Peripheral sensory neuropathy x
Generalised oedema Generalised oedema x x
Fluid retention Generalised oedema x x
Ventricular extrasystoles Ventricular extrasystoles x x
Myocardial ischaemia Myocardial ischaemia x x x x x
Electrocardiogram QT prolonged Electrocardiogram QT prolonged x
Electrocardiogram QT corrected interval prolonged x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x x x
Joint stiffness Joint stiffness x
Malnutrition Malnutrition x
Metabolic acidosis Metabolic acidosis x x x x
Myalgia Myalgia x
Abdominal pain upper Abdominal pain upper x x x
Dizziness postural Dizziness postural x
Euphoric mood Euphoric mood x x x x x
Eye irritation Eye irritation x x x x x
Hepatic enzyme increased Hepatic enzyme increased x x
Atrioventricular block second degree Atrioventricular block second degree x
Hepatobiliary disease Hepatobiliary disease x
Eye swelling Eye swelling x
Extrasystoles Extrasystoles x x x x x
Anaphylactoid reaction Anaphylactoid reaction x
Platelet count decreased Platelet count decreased x x
Electrocardiogram T wave amplitude decreased Electrocardiogram T wave amplitude decreased x x
Pruritus generalised Pruritus generalised x
Influenza like illness Influenza like illness x
Vein discolouration Vein discolouration x x x x x
Menopausal symptoms Hot flush x x x x
Hot flush Hot flush x x x x
Hypersomnia Hypersomnia x x x x x
Gastrointestinal hypomotility Intestinal hypomotility x x
Infusion site pain Infusion site pain x
Vasodilatation Vein distended x
Somnolence Somnolence x x x x x
Feeling hot Feeling hot x
Hypoxia Hypoventilation x x
Respiratory failure Hypoventilation x x
Hypoventilation Hypoventilation x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

palonosetron

Side effects:29
Source:FDA Structured Product Label

PALONOSETRON HYDROCHLORIDE / ALOXI

Side effects:49
Source:FDA

PALONOSETRON HYDROCHLORIDE / ALOXI

Side effects:54
Source:FDA

palonosetron

Side effects:68
Source:FDA Structured Product Label

PALONOSETRON

Side effects:72
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label