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Niacin

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: C04AC01, C10AD02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Diarrhoea Diarrhoea 10% - 14% 13% x x x x x x x x x x x
Nausea Nausea 4% - 11% 7% x x x x x x x x x x
Dermatitis Rash 0% - 5% 1% x x x x x x x x x x
Rash Rash 0% - 5% 1% x x x x x x x x x x
Vomiting Vomiting 2% - 9% 4% x x x x x x x x x x x
Cough Cough 2% - 8% 6% x x x x x x
Cough increased x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x
Angioedema Angioedema postmarketing x x x x x x x
Arrhythmia Arrhythmia postmarketing x x x x x x x x x x x
Asthenia Asthenia postmarketing 3% x x x x x x x x
Atrial fibrillation Atrial fibrillation postmarketing x x x x x x x x x x x
Dizziness Dizziness postmarketing x x x x x x x x
Syncope postmarketing x x x x x x x x
Dyspnoea Dyspnoea postmarketing x x x x x x x x
Eructation Eructation postmarketing 1% x x x x x x x
Flatulence Flatulence postmarketing x x x x x x x x
Flushing Flushing postmarketing, 55% - 69% x x x x x x x x x x
Generalized flushing x
Gout Gout postmarketing x x x x x x x x x
Hepatitis Hepatitis postmarketing x x x x x
Hypersensitivity Hypersensitivity postmarketing x x x x x x x
Hypotension Hypotension postmarketing x x x x x x x x x x x
Orthostatic hypotension Orthostatic hypotension postmarketing x x x x x
Jaundice Jaundice postmarketing x x x x x x x x x x
Laryngeal oedema Laryngeal oedema postmarketing x x x x x x x
Laryngospasm Laryngospasm postmarketing x x x x x x x
Myopathy Myopathy postmarketing x x x x x x
Nervousness Nervousness postmarketing x x x x x x x x
Tension Nervousness postmarketing x x x x x x x x
Palpitations Palpitations postmarketing 1% x x x x x x x x
Paraesthesia Paraesthesia postmarketing x x x x x x x
Tingling sensation x x x x x x x x x
Peptic ulcer Peptic ulcer postmarketing x x x x x x x x x x
Hyperhidrosis Sweating postmarketing 1% x x x x x x x x
Shock Syncope postmarketing x x x x x x x x
Shock x
Syncope Syncope postmarketing x x x x x x x x
Loss of consciousness Syncope postmarketing x x x x x x x x
Tachycardia Tachycardia postmarketing 0% x x x x x x x x
Urticaria Urticaria postmarketing 1% x x x x x x x x x
Burning sensation Burning sensation postmarketing x x x x x
Oedema peripheral Oedema peripheral postmarketing x x x x x x x
Migraine Migraine postmarketing 1% x x x x x x x
Tongue disorder Tongue oedema postmarketing x x x x x x x
Tongue disorder x
Tongue oedema Tongue oedema postmarketing x x x x x x x
Glucose tolerance decreased Glucose tolerance decreased postmarketing x x x x x x x x x
Rash pustular Vesiculobullous rash postmarketing x x x x x x x
Dermatitis bullous Vesiculobullous rash postmarketing x x x x x x x
Skin discolouration Skin discolouration postmarketing 1% x x x x x x
Dry skin Dry skin postmarketing x x x x x x x x x x
Myalgia Myalgia postmarketing x x x x x x x x
Musculoskeletal discomfort Myalgia postmarketing x x x x x x x x
Arthralgia 0% x
Skin burning sensation Skin burning sensation postmarketing x x x x x
Macular oedema Macular oedema postmarketing x x x x x
Vision blurred Vision blurred postmarketing x x x x x
Rash maculo-papular Rash maculo-papular postmarketing x x x x x x x x
Face oedema Face oedema postmarketing x x x x x x x
Insomnia Insomnia postmarketing x x x x x x x x
Abdominal pain Abdominal pain x
Gastrointestinal pain Abdominal pain x
Acanthosis nigricans Acanthosis nigricans x x x x
Alopecia Alopecia x
Amblyopia Amblyopia x x x x x
Angina pectoris Angina pectoris x
Decreased appetite Anorexia x
Arthralgia Arthralgia 0% x
Arthritis Arthritis 2% x
Ascites Ascites x
Bone disorder Bone disorder x
Bronchitis Bronchitis x
Bursitis Bursitis x
Cholelithiasis Cholelithiasis x
Cholestasis Cholestasis x
Dysphagia Dysphagia x
Dermatitis contact Dermatitis contact x
Fungal skin infection Fungal skin infection x
Diabetes mellitus Diabetes mellitus x x x x
Dyspepsia Dyspepsia 12% x x x x
Heartburn x
Eczema Eczema x
Oedema Oedema 0% - 1% x x x x x x x x
Oesophagitis Oesophagitis x
Eye disorder Eye disorder x
Faecal incontinence Faecal incontinence x
Body temperature increased Body temperature increased 3% x
Fibrosis Fibrosis x
Furuncle Furunculosis x
Gastrointestinal disorder Gastrointestinal disorder x x x x x
Gastrointestinal symptom NOS x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Glaucoma Glaucoma x
Headache Headache x x x x x
Haemoptysis Haemoptysis x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Hepatomegaly Hepatomegaly x
Hernia Hernia x
Herpes zoster Herpes zoster x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hyperinsulinism Hyperinsulinism x
Blood insulin increased Hyperinsulinism x
Hyperventilation Hyperventilation x
Hypoaesthesia Hypoaesthesia x
Hypothyroidism Hypothyroidism x
Libido increased Libido increased x
Disturbance in sexual arousal Libido increased x
Influenza Influenza 5% x
Jaundice cholestatic Jaundice cholestatic x
Hyperkeratosis Keratosis x
Hyperkeratosis x
Laryngitis Laryngitis x
Muscle spasms Cramps of lower extremities x x
Leukopenia Leukopenia x
Lung disorder Lung disorder x
Cystoid macular oedema Cystoid macular oedema x x x x
Breast pain Breast pain x
Hypertonia Hypertonia x
Necrosis Necrosis x
Pain Pain 2% - 7% x x x
Polyuria Polyuria x
Urine output increased Polyuria x
Prostatic disorder Prostatic disorder x
Pruritus Pruritus 0% - 3% 2% x x x x x x x x x x x
Rhabdomyolysis Rhabdomyolysis x x x x x
Rhinitis Rhinitis 31% x x x
Neoplasm skin Neoplasm skin x
Skin ulcer Skin ulcer x
Stomatitis Stomatitis x
Tinnitus Tinnitus 1% x
Vaginal inflammation Vaginal inflammation x
Vaginal infection Vaginal inflammation x
Angiopathy Angiopathy x x x x x
Vertigo Vertigo x
Dry mouth Dry mouth 0% x
Urinary retention Urinary retention x
Chills Chills 1% x x x x x x x x
Hypokinesia Hypokinesia x
Hepatic function abnormal Hepatic function abnormal x x
Application site reaction Application site reaction x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
High density lipoprotein decreased High density lipoprotein decreased x x x x
Liver function test abnormal Liver function test abnormal x
Raised liver function tests x
Mucous membrane disorder Mucous membrane disorder x
Malnutrition Malnutrition x
Skin hyperpigmentation Skin hyperpigmentation x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x
Muscle twitching Muscle twitching x
Feeling hot Sensation of heat x
Warmth x x x x x x x x
Sensation of warmth x
Hepatotoxicity Hepatotoxicity x
Skin exfoliation Skin exfoliation x
Erectile dysfunction Erectile dysfunction x
Xanthoma Xanthoma x
Erythema Redness x x x x x x x x
Abdominal distension Enlargement abdomen x
Metabolic syndrome Metabolic syndrome x x x x
Blood glucose increased Blood glucose increased x x x x
Blood uric acid increased Hyperuricaemia x x
Hyperuricaemia Hyperuricaemia x x
Muscular weakness Myasthenia x x
Arterial thrombosis Atherothrombosis x x x x
Somnolence Somnolence 1% x
Visual impairment Abnormal vision x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Nicotinic acid BP. Structural formula: / Nicotinic Acid

Side effects:30
Source:medicines.org.au

niacin

Side effects:20
Source:FDA Structured Product Label

niacin extended-release / Niaspan

Side effects:40
Source:FDA

NIACIN

Side effects:57
Source:FDA Structured Product Label

NIACIN

Side effects:61
Source:FDA Structured Product Label

NIACIN

Side effects:63
Source:FDA Structured Product Label

NIACIN

Side effects:63
Source:FDA Structured Product Label

NIACIN

Side effects:63
Source:FDA Structured Product Label

NICOTINIC ACID / NIASPAN 500MG

Side effects:114
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label