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BCNU

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01AD01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Urinary tract infection Urinary tract infection 8.33% - 21% 10.8% - 17% x x x
Convulsion Convulsion 1-10% - 37% 20% - 37.5% x x x
Hemiplegia Hemiplegia 1-10% - 40.8% 44.2% x x x
Body temperature increased Body temperature increased 17.5% 17.5% x x x
Depression Depression 15.8% - 16% 10% x x x
Wound Wound 14% - 16% 5% - 12% x
Nausea Nausea 8.18% - 21.7% 16.7% x x x x x x x x
Impaired healing Impaired healing 13.6% - 15.8% 11.7% x x
Headache Headache 1-10% - 27.5% 36.7% x x x x x x x
Vomiting Vomiting 2% - 21% 15.8% - 16% x x x x x x x x
Brain oedema Edema cerebral 4% - 23% 1% - 19% x
Brain oedema 3.64% - 22.5% 19.2% x x x
Speech disorder Speech disorder 10.8% 8.33% x x
Somnolence Somnolence 1- 10% - 13.6% 15% x x x
Confusional state Confusional state 1- 10% - 23.3% 20.8% x x x
Feeling abnormal Confusional state 1- 10% - 23.3% 20.8% x x x
Phlebitis Phlebitis 10% x
Thrombophlebitis Thrombophlebitis 10% 9.17% x x x
Aphasia Aphasia 1-10% - 17.5% 18.3% x x x
Intracranial pressure increased Intracranial pressure increased 3.64% - 9.17% 1.67% - 2% x x x
Personality disorder Personality disorder 8.33% 7.5% x x
Pneumonia Pneumonia 8.33% 7.5% x x x
Pulmonary embolism Pulmonary embolism 8.33% 8.33% x x x x
Abdominal pain Abdominal pain 8% - 8.33% 1.67% - 2% x x x
Gastrointestinal pain Abdominal pain 8% - 8.33% 1.67% - 2% x x x
Alopecia Alopecia 1-10% - 10% 11.7% x x x
Pain Pain 4% - 13.3% 15% x x x x x x
Anxiety Anxiety 6.67% 4.17% x x
VIIth nerve paralysis Facial paralysis 6.67% 4.17% x x
Haemorrhage Haemorrhage 6.67% 5.83% x x x
Haemoglobin Haemorrhage 6.67% 5.83% x x x
Conjunctival oedema Conjunctival oedema 6.67% 6.67% x x
Neuropathy peripheral Neuropathy 6.67% 10% x x
Brain abscess Brain abscess 6% 4% x x x
Cerebral haemorrhage Cerebral haemorrhage 6% 4% x x x
Stupor Stupor 1-10% - 6.36% x x x
Depressed level of consciousness Stupor 1-10% - 6.36% x x x
Hypoaesthesia Hypoaesthesia 5.83% 5% x x
Paraesthesia Paraesthesia 5.83% 8.33% x x
Face oedema Face oedema 5.83% 5% x x
Visual impairment Abnormal vision 5.83% 5.83% x x
Anaemia Anaemia 1-10% x x x x x
Decreased appetite Anorexia 1-10% x
Stomatitis Stomatitis 1-10% x
Abscess Abscess 3.64% - 1-10% 2.5% x x x
Diabetes mellitus Diabetes mellitus 5% 4.17% x x x
Grand mal convulsion Grand mal convulsion 5% 4.17% x x
Tonic-clonic seizures x x
Hallucination Hallucination 5% 3.33% x x
Tremor Tremor 5% 6.67% x x
Gait disturbance Gait disturbance 5% 5% x x
Muscular weakness Myasthenia 4.17% 5% x x
Hydrocephalus Hydrocephalus 3% - 1-10% 2% x x x x
Back pain Back pain 1% - 7% 3% - 3.33% x x x
Ataxia Ataxia 2% - 5.83% 4.17% x x x
Constipation Constipation 1% - 19.2% 11.7% - 12% x x x x
Dermatitis Rash 2% - 11.7% 10.8% x x x
Dermatitis x
Rash Rash 2% - 11.7% 10.8% x x x
Meningitis Meningitis 3.64% x x x x
Diarrhoea Diarrhoea 2% - 1-10% 4.17% x x x
Dizziness Dizziness 2% - 1-10% 9.17% x x x
Insomnia Insomnia 2% - 1-10% 5.83% x x x
Dyspnoea Dyspnoea 3.33% 6.67% x x
Amnesia Amnesia 1% - 9.17% 10% x x x
Cushing's syndrome Cushing's syndrome 3% - 3.33% 5% x x x
Candida infection Oral candidiasis 3% x
Oral candidiasis Oral candidiasis 3% x
Hyperglycaemia Hyperglycaemia 2% - 3% x x x
Hypertension Hypertension 3% x x x
Hyponatraemia Hyponatraemia 3% x x x
Eye disorder Eye disorder 2.5% 5% x x
Thinking abnormal Thinking abnormal 2% - 5.83% 8.33% x x x
Mental disability Thinking abnormal 2% - 5.83% 8.33% x x x
Coordination abnormal Coordination abnormal 2.5% 6.67% x x
Neck pain Neck pain 2% x x
Infection Infection 1% - 18.3% 20% x x x
Scotoma Scotoma 2% - 5% 6.67% x x
Tachycardia Tachycardia 2% x x x x x
Urinary incontinence Urinary incontinence 2% - 7.5% 7.5% x x x
Monoplegia Monoplegia 2% x x x
Oedema peripheral Oedema peripheral 2% - 9.17% 9.17% x x
Injury Accidental injury 1% - 5% 6.67% x x x
Hypokinesia Hypokinesia 1.67% 6.67% x x
Asthenia Asthenia 1% - 22% 15% x x x x
Chest pain Chest pain 1% - 5% 0% x x x x x x x x
Coma Coma 1% - 4.17% 5% x x
Dysphagia Dysphagia 1% x x x
Diplopia Diplopia 0.833% - 1-10% 5% x x x
Faecal incontinence Faecal incontinence 1% x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 1% x x
Hypersensitivity Hypersensitivity 1% - 1.67% 5% x x x x x x x
Hypokalaemia Hypokalaemia 1% x x x
Hypotension Hypotension 1% - 3% x x x x x x x
Leukocytosis Leukocytosis 1% x x
Pneumonia aspiration Pneumonia aspiration 1% x x
Thrombocytopenia Thrombocytopenia 1% x x x x x x x
Eye pain Eye pain 1% x x
Paranoia Paranoid reaction 1% x x
Sepsis Sepsis 1% x x x
Liver function test abnormal Liver function test abnormal 0.833% 5% x x
Gynaecomastia Gynaecomastia 1% x x
Myalgia Myalgia 1% x x
Musculoskeletal discomfort Myalgia 1% x x
Arrhythmia Arrhythmia x
Mental disorder Mental disorder x
Brain neoplasm Brain neoplasm x
Cerebral infarction Cerebral infarction x x
Connective tissue disorder Connective tissue disorder x
Cyst Cyst x
Oedema Oedema x x
Effusion Effusion x x
Extravasation Extravasation x x x
Fibrosis Fibrosis x x x
Flushing Flushing x x x x x
Gastrointestinal disorder Gastrointestinal disorder x
Hyperaemia Hyperaemia x x
Infertility Infertility x
Cerebrospinal fluid leakage Cerebrospinal fluid leakage x x x
Leukopenia Leukopenia x x x x x
Necrosis Necrosis x x
Neoplasm Neoplasm x x x x
Neutropenia Neutropenia x x
Pulmonary fibrosis Pulmonary fibrosis x x x x
Renal failure Renal failure x x x x
Retinal haemorrhage Retinal haemorrhage x
Swelling Swelling x x
Thrombosis Thrombosis x x x x x
Erythema Erythema x x
Meningitis bacterial Meningitis bacterial x
Encephalopathy Encephalopathy x x
Vasospasm Vasospasm x
Burning sensation Burning sensation x x
Agitation Agitation x x
Acute leukaemia Acute leukaemia x x x x x
Injection site reaction Injection site reaction x
Skin necrosis Skin necrosis x x
Skin exfoliation Skin necrosis x x
Adverse reaction Reaction aggravation x x x
Malnutrition Malnutrition x x
Skin hyperpigmentation Skin hyperpigmentation x x x x x
Teratogenicity Teratogenicity x
Hepatotoxicity Hepatotoxicity x x x
Lung infiltration Lung infiltration x x x x
Interstitial lung disease Lung fibrosis interstitial x
Azotaemia Azotaemia x x x x
Disease progression Disease progression x
Wound dehiscence Wound dehiscence x x
Pulmonary hypoplasia Pulmonary hypoplasia x x
Dysplasia Dysplasia x x x x x
Anaplastic astrocytoma Anaplastic astrocytoma x
Vision blurred Vision blurred x
Meningitis chemical Meningitis chemical x
Transaminases increased Transaminases increased x
Neoplasm recurrence Neoplasm recurrence x x x
Injection site pain Injection site burning x
Cerebral haematoma Cerebral haematoma x
Nephropathy toxic Nephropathy toxic x
Nephrotoxicity x x
Drug interaction Drug interaction x x
Febrile neutropenia Febrile neutropenia x
Pancytopenia Myelosuppression x x x x x
Pulmonary toxicity Pulmonary toxicity x x x x x
Venoocclusive disease Venoocclusive disease x
Gastrointestinal toxicity Gastrointestinal toxicity x x
Ocular toxicity Ocular toxicity x
Idiopathic pneumonia syndrome Idiopathic pneumonia syndrome x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

carmustine

Side effects:30
Source:FDA Structured Product Label

CARMUSTINE / BICNU

Side effects:29
Source:Health Canada

APPROVED NAME / BiCNU (Carmustine)

Side effects:31
Source:medicines.org.au

carmustine for injection / BiCNU

Side effects:26
Source:FDA

CARMUSTINE

Side effects:35
Source:FDA Structured Product Label

Carmustine

Side effects:83
Source:BC Cancer

CARMUSTINE

Side effects:94
Source:FDA Structured Product Label

CARMUSTINE / GLIADEL

Side effects:94
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label