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| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Constipation | Constipation | postmarketing, 9% - 12% |  | x |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Somnolence | Drowsiness | 9% |  |  |  |  |  | x |  | x |  |  |  | x | x |  |  |  |  |  |  | x | x | 
| Somnolence | postmarketing, 3% |  |  |  |  |  |  | x |  |  | x | x | x |  |  | x | x | x | x | x |  | x | 
| Nausea | Nausea | postmarketing, 7% - 9% |  | x |  |  | x | x | x | x | x | x |  | x | x | x | x | x | x | x | x | x | x | 
| Anxiety | Anxiety | 5% - 6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Apprehension |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Dizziness | Dizziness | postmarketing, 6% |  |  |  | x |  | x |  | x | x | x |  | x | x | x | x | x | x |  | x | x | x | 
| Syncope |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Lightheadedness |  |  |  |  |  |  |  |  | x | x |  |  | x |  | x | x | x | x |  |  |  | x | 
| Abdominal pain | Abdominal pain | 3% |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | x | x | 
| Abdominal colic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Gastrointestinal pain | Abdominal pain | 3% |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | x | x | 
| Decreased appetite | Anorexia | 3% |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x |  | x | x | x | x | 
| Appetite absent |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Diarrhoea | Diarrhoea | 3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dyspnoea | Dyspnoea | 3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Oedema peripheral | Oedema peripheral | 3% |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | x | x | 
| Disease progression | Disease progression | 3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Anaemia | Anaemia | 2% |  |  |  |  |  |  | x |  |  | x |  |  |  |  | x | x | x | x |  | x |  | 
| Chest pain | Chest pain | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Body temperature increased | Body temperature increased | 2% |  |  |  |  |  |  |  |  |  | x |  |  | x |  |  |  |  | x |  | x | x | 
| Leukopenia | Leukopenia | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Tremor | Tremor | 2% |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | 
| Tremor muscle |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Injury | Accidental injury | 2% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  | 
| Hyperhidrosis | Sweating increased | 2% |  |  |  |  |  |  |  |  |  | x |  |  |  | x |  |  |  |  |  | x |  | 
| Hyperhidrosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sweating |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x |  | x | 
| Dermatitis | Rash | postmarketing, 3% |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  |  |  | x | x | x | x | 
| Rash | Rash | postmarketing, 3% |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  |  |  | x | x | x | x | 
| Pain | Pain | postmarketing, 3% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ache |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Pain worsened |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Dry mouth | Dry mouth | postmarketing, 3% |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | 
| Vomiting | Vomiting | postmarketing, 2% |  | x |  |  | x | x | x | x | x | x |  | x | x | x | x | x | x | x | x | x | x | 
| Amenorrhoea | Amenorrhoea | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x |  | x | x | x | 
| Anaphylactic shock | Anaphylactic shock | postmarketing |  |  |  |  |  |  | x |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Anaphylactoid reaction |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  |  |  |  | x | 
| Asthenia | Asthenia | postmarketing, 2% |  |  |  |  |  |  |  | x | x |  | x | x | x | x |  |  |  | x | x | x | x | 
| Fatigue | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x | 
| Back pain | Back pain | postmarketing |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  | x |  | 
| Bronchospasm | Bronchospasm | postmarketing |  |  |  |  |  |  | x |  |  |  | x |  |  |  |  |  |  |  | x |  | x | 
| Confusional state | Confusional state | postmarketing, 4% |  |  |  |  |  |  | x |  |  | x | x | x |  |  | x | x | x | x | x | x | x | 
| Feeling abnormal | Confusional state | postmarketing, 4% |  |  |  |  |  |  | x |  |  | x | x | x |  |  | x | x | x | x | x | x | x | 
| Malaise | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Feeling abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Drug hypersensitivity | Drug hypersensitivity | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Fatigue | Fatigue | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x | 
| Headache | Headache | postmarketing |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hyperpathia | Hyperpathia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hyperaesthesia | Hyperpathia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Intestinal obstruction | Intestinal obstruction | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Lethargy | Lethargy | postmarketing |  |  |  |  |  | x |  |  |  | x |  | x |  |  | x | x | x | x | x | x |  | 
| Hypertonia | Hypertonia | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  | x | 
| Neuralgia | Neuralgia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Osteoarthritis | Osteoarthritis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pruritus | Pruritus | postmarketing |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x | 
| Pulmonary oedema | Pulmonary oedema | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Vertigo | Vertigo | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Malaise | Malaise | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Discomfort | Malaise | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Ill-defined disorder | Malaise | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Thinking abnormal | Thinking abnormal | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | 
| Mental disability | Thinking abnormal | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | 
| Ileus | Ileus | postmarketing |  |  |  |  |  |  |  |  |  |  | x |  |  | x |  |  |  |  | x |  |  | 
| Abdominal distension | Abdominal distension |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Addison's disease | Addison's disease |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Alcoholism | Alcoholism |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Alcohol abuse | Alcoholism |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Amblyopia | Amblyopia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Amnesia | Amnesia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Haemolytic anaemia | Haemolytic anaemia |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Apnoea | Apnoea |  |  |  | x |  |  |  |  |  |  | x |  | x |  | x | x | x | x | x |  |  | x | 
| Arthralgia | Arthralgia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Musculoskeletal discomfort | Arthralgia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Ataxia | Ataxia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Atelectasis | Atelectasis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Pneumothorax | Atelectasis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Atrial fibrillation | Atrial fibrillation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Mental disorder | Mental disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Blister | Blister |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dermatitis bullous | Blister |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Brain neoplasm | Brain neoplasm |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Breast disorder | Breast disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Breast feeding | Breast feeding |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cachexia | Cachexia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cardiovascular disorder | Cardiovascular disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Cheyne-Stokes respiration | Cheyne-Stokes respiration |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Coma | Coma |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x |  |  | x | 
| Infection | Infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Conjunctivitis | Conjunctivitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Connective tissue disorder | Connective tissue disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Cough | Cough |  |  |  |  | x | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Cyanosis | Cyanosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Libido decreased | Libido decreased |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | 
| Disturbance in sexual arousal | Libido decreased |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | x | x | 
| Decubitus ulcer | Decubitus ulcer |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Dysphagia | Dysphagia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Dehydration | Dehydration |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Delirium | Delirium |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x |  |  |  | 
| Dermatitis contact | Dermatitis contact |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Diplopia | Diplopia |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | 
| Drug abuse | Drug abuse |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Opioid abuse |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug tolerance | Drug tolerance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dysgeusia | Dysgeusia |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x |  |  | 
| Taste metallic |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dyskinesia | Dyskinesia |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dyspepsia | Dyspepsia |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | 
| Dysuria | Dysuria |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Oedema | Oedema |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Eosinophilia | Eosinophilia |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Eye disorder | Eye disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Faecalith | Faecalith |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Faecaloma | Faecalith |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Flatulence | Flatulence |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Flushing | Flushing |  |  |  |  |  |  | x |  | x | x |  | x | x |  | x |  |  |  |  | x | x | x | 
| Gastroenteritis | Gastroenteritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Gastrooesophageal reflux disease | Gastrooesophageal reflux disease |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Gastrointestinal disorder | Gastrointestinal disorder |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  | x | 
| Gynaecomastia | Gynaecomastia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hallucination | Hallucination |  |  |  |  |  |  |  | x |  | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Head injury | Head injury |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cardiac arrest | Cardiac arrest |  |  |  | x |  |  | x |  | x | x | x |  | x | x | x | x | x | x | x |  |  | x | 
| Hepatitis | Hepatitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hiccups | Hiccups |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Hypercapnia | Hypercapnia |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  | 
| Carbon dioxide increased | Hypercapnia |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  | 
| Hyperglycaemia | Hyperglycaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypersensitivity | Hypersensitivity |  |  |  |  |  |  | x | x |  | x |  | x |  |  |  |  |  |  |  |  |  | x | 
| Hypertension | Hypertension |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x |  | 
| Hypoaesthesia | Hypoaesthesia |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  | 
| Hypogonadism | Hypogonadism |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  |  |  | 
| Hypokalaemia | Hypokalaemia |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Hyponatraemia | Hyponatraemia |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Hypotension | Hypotension |  |  |  |  |  |  |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | 
| Hypotensive |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Orthostatic hypotension | Orthostatic hypotension |  |  |  |  |  |  | x | x |  | x |  |  |  | x |  |  |  |  |  |  | x | x | 
| Hypovolaemic shock | Hypovolaemic shock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Inappropriate antidiuretic hormone secretion | Inappropriate antidiuretic hormone secretion |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Influenza | Influenza |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  | 
| Laryngospasm | Laryngospasm |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Lung disorder | Lung disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Mediastinal disorder | Mediastinal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Miosis | Miosis |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x |  |  |  |  | x | x | x | 
| Pupils pinpoint |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | x | 
| Muscle spasms | Cramp muscle |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  | x | 
| Muscle spasms |  |  |  |  |  |  | x |  | x | x |  |  | x | x | x |  |  |  |  |  |  | x | 
| Hypotonia | Muscle tone flaccid |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Muscle rigidity | Muscle rigidity |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  |  | 
| Mydriasis | Mydriasis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Myoclonus | Myoclonus |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Nervous system disorder | Nervous system disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Nervousness | Nervousness |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  |  | x | 
| Tension | Nervousness |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  |  | x | 
| Nodule | Nodule |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Nystagmus | Nystagmus |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | 
| Oliguria | Oliguria |  |  |  |  | x | x |  |  |  | x | x |  | x |  |  | x | x | x | x |  |  |  | 
| Pallor | Pallor |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Palpitations | Palpitations |  |  |  |  |  |  |  |  | x | x |  |  | x | x | x | x | x | x | x | x | x | x | 
| Ileus paralytic | Ileus paralytic |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Paraesthesia | Paraesthesia |  |  |  |  |  |  |  |  |  |  | x | x |  |  | x |  |  |  | x | x | x | x | 
| Phlebitis | Phlebitis |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Piloerection | Piloerection |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Cutis anserina |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Post herpetic neuralgia | Post herpetic neuralgia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Psychotic disorder | Psychotic disorder |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Pulmonary embolism | Pulmonary embolism |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Anorectal disorder | Rectal disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Renal failure | Renal failure |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Renal impairment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Respiratory failure | Respiratory insufficiency |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Respiratory failure aggravated |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Hypoventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Rhabdomyolysis | Rhabdomyolysis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Rhinitis | Rhinitis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Convulsion | Convulsion |  |  |  |  | x | x | x |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | 
| Chills | Shivering |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Chills |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x |  |  |  |  | x | x | x | 
| Rigors |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Shock | Shock |  |  |  | x |  |  | x |  | x | x |  |  | x | x | x | x | x | x | x |  |  | x | 
| Syncope |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Sleep disorder | Sleep disturbance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Sneezing | Sneezing |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Stomatitis | Stomatitis |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Withdrawal syndrome | Withdrawal syndrome |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | 
| Swelling | Swelling |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Syncope | Syncope |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Loss of consciousness | Syncope |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Tachycardia | Tachycardia |  |  |  |  |  |  | x |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | 
| Supraventricular tachycardia | Supraventricular tachycardia |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Thirst | Thirst |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Thrombocytopenia | Thrombocytopenia |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x |  | x |  | 
| Ventricular tachycardia | VT |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Ulcer | Ulcer |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Erythema | Erythema |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Urethral stenosis | Urethral stenosis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Urinary tract infection | Urinary tract infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Urethral disorder | Urinary tract disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Urinary tract disorder | Urinary tract disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Urticaria | Urticaria |  |  | x |  | x | x |  |  | x | x |  | x | x | x | x | x | x | x | x | x |  | x | 
| Welts |  |  |  |  | x | x |  |  |  | x |  |  | x |  |  |  |  |  |  |  |  |  | 
| Angiopathy | Angiopathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Vasodilation procedure | Vasodilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  | x |  | 
| Weight decreased | Weight decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Wheezing | Wheezing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Yawning | Yawning |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Urinary retention | Urinary retention |  |  |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Stupor | Stupor |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| Depressed level of consciousness | Stupor |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | x | 
| CNS depression NOS |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Agitation | Agitation |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Hyperkinesia |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Apathy | Apathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Flat affect | Apathy |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Mood swings | Mood swings |  |  |  |  |  |  | x |  |  |  |  | x | x |  |  |  |  |  |  | x |  | x | 
| Affect lability | Mood swings |  |  |  |  |  |  | x |  |  |  |  | x | x |  |  |  |  |  |  | x |  | x | 
| Peroneal nerve palsy | Footdrop |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Drug withdrawal syndrome | Withdrawal symptom |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Drug withdrawal syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cough decreased | Cough decreased |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x | 
| Intracranial pressure increased | Intracranial pressure increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x |  |  | 
| Liver function test abnormal | Liver function test abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  |  |  | 
| Accidental overdose | Accidental overdose |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Biliary colic | Biliary colic |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | x |  | 
| Spasm biliary |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bone pain | Bone pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Eye pain | Eye pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Injection site pain | Injection site pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Dry skin | Dry skin |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Gastric atony | Gastric atony |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Impaired gastric emptying | Gastric atony |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Delayed gastric emptying |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Urinary hesitation | Urinary hesitation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | 
| Prolonged labour | Prolonged labour |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Lacrimation increased | Lacrimation increased |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Menstruation irregular | Menstruation irregular |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Respiratory arrest | Respiratory arrest |  |  |  | x |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x |  |  | x | 
| Malnutrition | Malnutrition |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x |  |  | 
| Skin disorder | Unspecified disorder of skin and subcutaneous tissue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Muscle twitching | Muscle twitching |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Chest discomfort | Chest tightness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Renal impairment | Function kidney decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Renal impairment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Disorientation | Disorientation |  |  |  |  |  |  |  |  | x | x |  |  | x |  | x |  |  |  |  | x |  |  | 
| Dysphoria | Dysphoria |  |  |  |  |  |  | x |  | x | x |  | x | x | x | x |  |  |  |  | x |  | x | 
| Hallucination, visual | Hallucination, visual |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tenderness | Tenderness |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abnormal dreams | Abnormal dreams |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x |  | 
| Dysarthria | Slurred speech |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
| Respiratory depression | Respiratory depression |  |  |  | x | x | x | x |  | x | x | x | x |  | x | x |  |  | x | x | x |  | x | 
| Pulmonary function test decreased | Respiratory depression |  |  |  | x | x | x | x |  | x | x | x | x |  | x | x |  |  | x | x | x |  | x | 
| Muscle contractions involuntary | Muscle contractions involuntary |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x | 
| Euphoric mood | Euphoric mood |  |  |  |  | x |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | x | x | 
| Sedation | Tranquillisation excessive |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Heart rate irregular | Heart rate irregular |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Erectile dysfunction | Erectile dysfunction |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x |  |  |  | 
| Sepsis | Sepsis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | 
| Hepatobiliary disease | Hepatobiliary disease |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Drug dependence | Dependence psychological |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Drug dependence |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Dependence | Dependence physiological |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Dependence |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypersexuality | Hypersexuality |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Induration | Induration |  |  |  |  |  |  |  | x |  | x |  |  |  |  |  |  |  |  |  |  |  |  | 
| Anaphylactoid reaction | Anaphylactoid reaction |  |  |  |  |  |  |  |  |  | x |  | x | x |  |  |  |  |  |  |  |  | x | 
| Vision blurred | Vision blurred |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | 
| Abdominal pain upper | Stomach cramps |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Cold sweat | Sticky skin |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Sticky skin | Sticky skin |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hyperkinesia | Hyperkinesia |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bladder pain | Bladder spasm |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Bladder spasm | Bladder spasm |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Balance disorder | Unsteadiness |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  | x | x | 
| Bradycardia | Bradycardia |  |  |  |  |  |  |  |  | x | x | x |  | x |  | x | x | x | x | x | x | x | x | 
| Coordination abnormal | Coordination abnormal |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x |  |  |  |  | x |  |  | 
| Visual impairment | Visual disturbance |  |  |  |  |  |  |  |  | x | x |  |  | x | x | x |  |  |  |  |  |  |  | 
| Visual impairment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Gait disturbance | Gait disturbance |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Compulsions | Compulsions |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drug interaction | Drug interaction |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x |  | 
| Presyncope | Presyncope |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | 
| Substance abuse | Substance abuse |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematocrit decreased | Haematocrit decreased |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Oxygen saturation decreased | Oxygen saturation decreased |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  | 
| Spontaneous penile erection | Spontaneous penile erection |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Insomnia | Insomnia |  |  |  |  |  |  |  |  | x |  | x |  | x | x | x |  |  |  | x | x | x | x | 
| Ureteral spasm | Ureteral spasm |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Polyuria | Diuretic effect |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | x |  |  |  |  | 
| Breakthrough pain | Breakthrough pain |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Haemorrhagic urticaria | Haemorrhagic urticaria |  |  |  |  |  |  |  |  | x |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Nasopharyngitis | Rhinorrhoea |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Rhinorrhoea | Rhinorrhoea |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  |  | x | 
| Respiratory disorder | Respiration abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Respiration abnormal | Respiration abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cardiovascular insufficiency | Circulatory depression |  |  |  | x |  |  | x |  | x | x |  |  | x | x | x | x | x | x | x |  |  | x | 
| Genital swelling | Genital swelling |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Stereotypy | Punding |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ejaculation disorder | Abnormal ejaculation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Loss of libido | Loss of libido |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypoxia | Hypoventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Hypoventilation | Hypoventilation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  |  | 
| Non-cardiogenic pulmonary oedema | Non-cardiogenic pulmonary oedema |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 5 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 6 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 11 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 15 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 25 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 30 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 36 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 37 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 38 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 43 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 53 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 58 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
	  
		| Side effects: | 58 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 69 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 70 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 70 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 78 | 
|---|
		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 85 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 93 | 
|---|
		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 110 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |