Addison's disease

Definition: An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.

Synonyms (terms occurring on more labels are shown first): Addison's disease, Primary adrenal insufficiency, hypocortisolism, Addisons disease

More information: PubMed search and possibly Wikipedia