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ATC Code: C08CA07

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Headache Headache 22% 15% x x
Oedema peripheral Oedema peripheral 7% - 27% 10% x x
Dizziness Dizziness 3% - 7% 4% x x
Syncope x x
Pharyngitis Pharyngitis 5% 4% x x
Vasodilation procedure Vasodilation 4% 2% x x
Palpitations Palpitations 3% 1% x x
Sinusitis Sinusitis 3% 2% x x
Chest pain Chest pain 2% 1% x x
Dermatitis Rash 2% 1% x x
Rash Rash 2% 1% x x
Nausea Nausea 2% 1% x x
Alopecia Alopecia x x
Amblyopia Amblyopia x x
Amnesia Amnesia x x
Anaemia Anaemia x x
Angioedema Angioedema x x
Decreased appetite Anorexia x x
Anxiety Anxiety x x
Arthralgia Arthralgia x x
Musculoskeletal discomfort Arthralgia x x
Myalgia x x
Arthritis Arthritis x x
Asthma Asthma x x
Ataxia Ataxia x x
Atrial fibrillation Atrial fibrillation x x
Blepharitis Blepharitis x x
Cellulitis Cellulitis x x
Colitis Colitis x x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Malaise x x
Conjunctivitis Conjunctivitis x x
Libido decreased Libido decreased x x
Disturbance in sexual arousal Libido decreased x x
Dysphagia Dysphagia x x
Dermatitis exfoliative Dermatitis exfoliative x x
Fungal skin infection Fungal skin infection x x
Diabetes mellitus Diabetes mellitus x x
Diarrhoea Diarrhoea x x
Dysgeusia Dysgeusia x x
Dyspepsia Dyspepsia x x
Dyspnoea Dyspnoea x x
Dysuria Dysuria x x
Ear pain Ear pain x x
Ecchymosis Ecchymosis x x
Oedema Oedema x
Epistaxis Epistaxis x x
Body temperature increased Body temperature increased x x
Flatulence Flatulence x x
Vitreous floaters Vitreous floaters x x
Gastritis Gastritis x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x
Gingival hyperplasia Gingival hyperplasia x x
Glaucoma Glaucoma x x
Glossitis Glossitis x x
Gout Gout x x
Gynaecomastia Gynaecomastia x x
Cardiac failure congestive Cardiac failure congestive x x
Haematuria Haematuria x x
Hepatomegaly Hepatomegaly x x
Herpes simplex Herpes simplex x x
Herpes zoster Herpes zoster x x
Hypersensitivity Hypersensitivity x x
Hypoaesthesia Hypoaesthesia x x
Hypokalaemia Hypokalaemia x x
Hypotension Hypotension x x
Orthostatic hypotension Orthostatic hypotension x x
Influenza Influenza x x
Eye pruritus Eye pruritus x x
Keratitis Keratoconjunctivitis x x
Laryngitis Laryngitis x x
Muscle spasms Cramps of lower extremities x x
Leukopenia Leukopenia x x
Melaena Melaena x x
Hypertonia Hypertonia x x
Myocardial infarction Myocardial infarction x x
Acute coronary syndrome Myocardial infarction x x
Myositis Myositis x x
Nervousness Nervousness x x
Tension Nervousness x x
Nocturia Nocturia x x
Otitis media Otitis media x x
Paraesthesia Paraesthesia x x
Petechiae Petechiae x x
Pleural effusion Pleural effusion x x
Pruritus Pruritus x x
Rales Rales x x
Retinal detachment Retinal detachment x x
Rhinitis Rhinitis x x
Skin ulcer Skin ulcer x x
Cerebrovascular accident Cerebrovascular accident x x
Hyperhidrosis Sweating x x
Shock Syncope x x
Syncope Syncope x x
Loss of consciousness Syncope x x
Tachycardia Tachycardia x x
Supraventricular tachycardia Supraventricular tachycardia x x
Tenosynovitis Tenosynovitis x x
Thyroiditis Thyroiditis x x
Tinnitus Tinnitus x x
Tremor Tremor x x
Pollakiuria Pollakiuria x x
Urticaria Urticaria x x
Vaginal inflammation Vaginal inflammation x x
Vaginal infection Vaginal inflammation x x
Venous insufficiency Venous insufficiency x x
Vertigo Vertigo x x
Weight increased Weight increased x x
Weight decreased Weight decreased x x
Dry mouth Dry mouth x x
Chills Chills x x
Atrioventricular block first degree Atrioventricular block first degree x x
Rash pustular Rash pustular x x
Stomatitis Mouth ulceration x x
Mouth ulceration Mouth ulceration x x
Migraine Migraine x x
Blood urea increased Blood urea increased x x
Ventricular extrasystoles Ventricular extrasystoles x x
Liver function test abnormal Liver function test abnormal x x
Skin discolouration Skin discolouration x x
Dry skin Dry skin x x
Malaise Malaise x x
Discomfort Malaise x x
Ill-defined disorder Malaise x x
Myalgia Myalgia x x
Wheezing Wheezing inspiratory x x
Chest discomfort Chest tightness x x
Increased appetite Increased appetite x x
Thinking abnormal Thinking abnormal x x
Mental disability Thinking abnormal x x
Abnormal dreams Abnormal dreams x x
Erectile dysfunction Erectile dysfunction x
Rash maculo-papular Rash maculo-papular x x
Face oedema Face oedema x x
Cough Cough increased x x
Cardiac murmur Systolic ejection murmur x x
Blindness unilateral Unilateral vision loss x x
Cerebral ischaemia Cerebral ischaemia x x
Insomnia Insomnia x x
Muscular weakness Myasthenia x x
Somnolence Somnolence x x
Vaginal haemorrhage Vaginal haemorrhage x x
Lacrimation increased Tearing eyes x x
Visual impairment Abnormal vision x x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:127
Source:FDA Structured Product Label


Side effects:129
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label