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More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: V08AB04

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Headache Headache 16.4% x x x
Nausea Nausea 1.2% - 7.3% x x x
Vomiting Vomiting 3.6% x x x
Pain Pain 2.8% x x x
Back pain Back pain 2.2% x x
Menopausal symptoms Hot flush 1.5% x x x
Hot flush Hot flush 1.5% x x x
Pain in extremity Leg pain 1.4% x x
Burning sensation Burning sensation 1.4% x x x
Neck pain Neck pain 1.1% x x
Hypotension Hypotension 1.1% x x x
Hypotensive x x x
Feeling hot Warmth 1.1% x
Sensation of warmth x x x
Abdominal pain Abdominal cramps x
Angina pectoris Angina pectoris x
Decreased appetite Anorexia x
Anuria Anuria x
Anxiety Anxiety x x
Apprehension x x
Aphasia Aphasia x x
Dysphasia x x
Apnoea Apnoea x x x
Arrhythmia Arrhythmia x
Asthenia Asthenia x x
Fatigue x
Asthma Asthma x x x
Ataxia Ataxia x x
Bronchospasm Bronchospasm x x
Cardiovascular disorder Cardiovascular disorder x x x
Transient ischaemic attack Transient ischaemic attack x
Chest pain Chest pain x x x
Choking Choking x x
Coma Coma x x x
Infection Infection x x x
Confusional state Confusional state x x x
Feeling abnormal Confusional state x x x
Malaise x x
Conjunctivitis Conjunctivitis x x x
Cyanosis Cyanosis x
Depersonalisation Depersonalisation x x
Diarrhoea Diarrhoea x x
Dizziness Dizziness x x x
Syncope x x x
Lightheadedness x x
Dysgeusia Dysgeusia x x
Dyspnoea Dyspnoea x x x
Echolalia Echolalia x x
Dermatitis Rash x x x
Rash Rash x x x
Extravasation Extravasation x x x
Facial neuralgia Facial neuralgia x x
Muscle contractions involuntary Fasciculation x x
Fatigue Fatigue x
Body temperature increased Body temperature increased x x
Fever chills x
Flushing Flushing x x x
Guillain-Barre syndrome Guillain-Barre syndrome x x
Hallucination Hallucination x x
Cardiac arrest Cardiac arrest x x x
Dyspepsia Heartburn x x
Haematoma Haematoma x x x
Haematuria Haematuria x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Hyperaesthesia Hyperaesthesia x
Hypertension Hypertension x x x
Infarction Infarction x
Irritability Irritability x x
Eye pruritus Eye pruritus x
Nephropathy Nephropathy x
Laryngeal oedema Laryngeal oedema x x x
Muscle spasms Cramps of lower extremities x x
Cramp muscle x x
Muscle spasms x
Malaise Malaise and fatigue x
Malaise x x
Meningism Meningism x x
Meningitis aseptic Meningitis aseptic x x
Hypotonia Muscle tone flaccid x x
Hypertonia Hypertonia x x
Muscle spasticity Muscle spasticity x x
Musculoskeletal pain Musculoskeletal pain x x
Myelitis Myelitis x x
Myelitis transverse Myelitis transverse x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Nasal congestion Nasal congestion x x x
Necrosis Necrosis x
Nephrotic syndrome Nephrosis x x x
Neutropenia Neutropenia x x x
Hypoaesthesia Numbness x x
Sensory loss Numbness x x
Oliguria Oliguria x
Pallor Pallor x x x
Paraesthesia Paraesthesia x x x
Tingling sensation x
Neuropathy peripheral Neuropathy peripheral x x
Petechiae Petechiae x x
Pruritus Pruritus x x x
Pulmonary oedema Pulmonary oedema x x x
Renal failure Renal failure x x x
Rhinitis Rhinitis x x x
Sciatica Sciatica x x
Convulsion Convulsion x x x
Convulsive seizure x x
Shock Shock x x x
Syncope x x x
Sneezing Sneezing x x x
Spinal cord injury Spinal cord injury x
Hyperhidrosis Sweating x x
Sweating increased x
Swelling Swelling x x x
Syncope Syncope x x x
Loss of consciousness Syncope x x x
Tachycardia Tachycardia x x x
Thrombophlebitis Thrombophlebitis x x x
Tinnitus Tinnitus x x
Tremor Tremor x x x
Urticaria Urticaria x x x
Vasodilation procedure Vasodilation x x x
Venous thrombosis Venous thrombosis x
Ventricular fibrillation Ventricular fibrillation x x
Wheezing Wheezing x x
Urinary retention Urinary retention x x x
Meningitis bacterial Meningitis bacterial x x
Chills Chills x x
Sinus bradycardia Sinus bradycardia x x
Arterial spasm Arterial spasm x
Stupor Stupor x x
Depressed level of consciousness Stupor x x
Agitation Agitation x x
Periorbital oedema Periorbital oedema x
Musculoskeletal stiffness Neck stiffness x x
Nuchal rigidity Neck stiffness x x
Ventricular extrasystoles Ventricular extrasystoles x
Ventricular bigeminy x
Retroperitoneal haemorrhage Retroperitoneal haemorrhage x
Myocardial ischaemia Myocardial ischaemia x
Muscular weakness Muscular weakness x x
Skin necrosis Skin necrosis x x x
Skin exfoliation Skin necrosis x x x
Injection site pain Injection site pain x x x
Hyperreflexia Hyperreflexia x x
Arterial thrombosis Arterial thrombosis x
Blindness cortical Blindness cortical x
Discomfort Malaise x x
Discomfort x
Ill-defined disorder Malaise x x
Myalgia Myalgia x x
Musculoskeletal discomfort Myalgia x x
Cardiac fibrillation Cardiac fibrillation x
Chest discomfort Chest tightness x
Retching Retching x x x
Asterixis Asterixis x x
Disorientation Disorientation x x
Amnesia Amnesia transient x
Areflexia Areflexia x x
Neurotoxicity Neurotoxicity x x
Eye irritation Eye irritation x x
Throat tightness Throat tightness x
Grimacing Grimacing x
Extrasystoles Ventricular bigeminy x
Conjunctival oedema Chemosis x x x
VIth nerve paralysis VIth nerve paralysis x x
Peripheral coldness Peripheral coldness x x
Anaphylactic shock Anaphylactoid reaction x
Anaphylactoid reaction Anaphylactoid reaction x
Cauda equina syndrome Cauda equina syndrome x x
Lacrimation increased Lacrimation x x x
Dyskinesia Movements involuntary x x
Bradycardia Bradycardia x
Electrocardiogram ST segment depression Electrocardiogram ST segment depression x
Electrocardiogram abnormal Electrocardiogram abnormal x x
Paralysis Paralysis x x x
Sinus arrest Sinus arrest x
Face oedema Face oedema x
Visual impairment Visual disturbance x x x
Cough Cough increased x x x
Cardio-respiratory arrest Cardio-respiratory arrest x
Contrast media reaction Contrast media reaction x x x
Electrocardiogram change Electrocardiogram change x
Electroencephalogram abnormal Wave slowing x x
Dysacusis Echoacousia x x
Deafness Hearing impaired x x
Hearing impaired Hearing impaired x x
Heart disease congenital Cyanotic heart disease x
Cardiac failure Decompensation cardiac x
Injury Injury x x x
Blindness Unspecified visual loss x x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:105
Source:FDA Structured Product Label


Side effects:120
Source:FDA Structured Product Label


Side effects:122
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label