Rosiglitazone
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
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Placebo
|
Labels
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1
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2
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3
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4
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5
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6
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7
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8
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9
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Anaemia
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Anaemia
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common, 7.1%
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|
x
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x
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x
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x
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x
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x
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x
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x
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x
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Nasopharyngitis
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Nasopharyngitis
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6.3% - 6.9%
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|
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|
|
|
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x
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x
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x
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Upper respiratory tract infection
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Upper respiratory tract infection
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4.3% - 9.9%
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8.7%
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|
|
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x
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x
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x
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Hypertension
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Hypertension
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4.4% - 6.1%
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|
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|
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x
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x
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x
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x
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Headache
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Headache
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5.4% - 20%
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5%
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Thrombocytopenia
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Thrombocytopenia
|
common
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x
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|
|
|
|
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Back pain
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Back pain
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4% - 9%
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3.8%
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x
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x
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x
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x
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x
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x
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x
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x
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Arthralgia
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Arthralgia
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4.2% - 5%
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x
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x
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x
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Musculoskeletal discomfort
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Arthralgia
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4.2% - 5%
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x
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x
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x
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Myalgia
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|
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x
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|
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Hyperglycaemia
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Hyperglycaemia
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3.9% - 10%
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5.7%
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x
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x
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x
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x
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x
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x
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x
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x
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Asthenia
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Fatigue
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1.9% - 9%
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5%
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x
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x
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x
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x
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x
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x
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x
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x
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Fatigue
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Fatigue
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1.9% - 9%
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5%
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x
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x
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x
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x
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x
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x
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x
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x
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Sinusitis
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Sinusitis
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3% - 12%
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4.5%
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x
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x
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x
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x
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x
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x
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x
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x
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Diarrhoea
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Diarrhoea
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2.3% - 35%
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3.3%
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x
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x
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x
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x
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x
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x
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x
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x
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Hypoglycaemia
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Hypoglycaemia
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1% - 13%
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0.2%
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Anaphylactic shock
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Anaphylactic shock
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very rare, postmarketing
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x
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x
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x
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x
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x
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Angioedema
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Angioedema
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very rare, postmarketing
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x
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x
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x
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x
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x
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x
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Dermatitis
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Rash
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very rare, postmarketing
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x
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x
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x
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x
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x
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Rash
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Rash
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very rare, postmarketing
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x
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|
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x
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x
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x
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x
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Cardiac failure congestive
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Cardiac failure congestive
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postmarketing, rare
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x
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x
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x
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x
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x
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x
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x
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x
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Hepatitis
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Hepatitis
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postmarketing
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|
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x
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x
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x
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x
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x
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x
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x
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Pleural effusion
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Pleural effusion
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postmarketing
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x
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x
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x
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x
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x
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x
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x
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Pruritus
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Pruritus
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very rare, postmarketing
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x
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x
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x
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x
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x
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Pulmonary oedema
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Pulmonary oedema
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postmarketing, rare
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x
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x
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x
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x
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x
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x
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x
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x
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Erythema multiforme
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Stevens-Johnson syndrome
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postmarketing
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x
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x
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x
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Stevens-Johnson syndrome
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Stevens-Johnson syndrome
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postmarketing
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x
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x
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x
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Urticaria
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Urticaria
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very rare, postmarketing
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x
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x
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x
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x
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x
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x
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Hepatic failure
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Hepatic failure
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postmarketing
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|
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x
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x
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x
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x
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x
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x
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x
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x
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Hepatic function abnormal
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Hepatic function abnormal
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rare
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x
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Visual acuity reduced
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Visual acuity reduced
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postmarketing
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x
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x
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x
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x
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Macular oedema
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Macular oedema
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postmarketing, rare
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x
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x
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x
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x
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x
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Diabetes mellitus
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Worsening of diabetes
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postmarketing
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x
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x
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x
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Diabetes mellitus
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x
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Weight increased
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Weight increased
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very rare
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x
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x
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x
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Infection
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Infection
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x
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x
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x
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x
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x
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Connective tissue disorder
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Connective tissue disorder
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x
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Constipation
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Constipation
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x
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x
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Dizziness
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Dizziness
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x
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Oedema
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Oedema
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Eye disorder
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Eye disorder
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x
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Multiple fractures
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Fracture
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x
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x
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x
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x
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x
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Fracture
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Fracture
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x
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x
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x
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x
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x
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Gastrointestinal disorder
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Gastrointestinal disorder
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x
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Cardiac disorder
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Cardiac disorder
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x
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Cardiac failure
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Cardiac failure
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x
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x
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x
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x
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x
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x
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Hyperbilirubinaemia
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Hyperbilirubinaemia
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x
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x
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x
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x
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x
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x
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x
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x
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Hypercholesterolaemia
|
Hypercholesterolaemia
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x
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Hyperlipidaemia
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Hyperlipidaemia
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x
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Hypertriglyceridaemia
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Hypertriglyceridaemia
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x
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Blood triglycerides increased
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Hypertriglyceridaemia
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x
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Immune system disorder
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Immune system disorder
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x
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Ischaemia
|
Ischaemia
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x
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Leukopenia
|
Leukopenia
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x
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Myocardial infarction
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Myocardial infarction
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x
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x
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Acute coronary syndrome
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Myocardial infarction
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x
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x
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Nausea
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Nausea
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x
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x
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x
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Nervous system disorder
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Nervous system disorder
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x
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Ligament sprain
|
Sprain
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x
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Cerebrovascular accident
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Cerebrovascular accident
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|
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x
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Oedema peripheral
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Oedema peripheral
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x
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Myocardial ischaemia
|
Myocardial ischaemia
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x
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x
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Ketonuria
|
Ketonuria
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|
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x
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x
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x
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Malnutrition
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Malnutrition
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x
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Myalgia
|
Myalgia
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x
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Volume blood increased
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Volume plasma increased
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x
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x
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x
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x
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x
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x
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x
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x
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Increased appetite
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Increased appetite
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x
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x
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Hepatic enzyme increased
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Hepatic enzyme increased
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x
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Hepatobiliary disease
|
Hepatobiliary disease
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|
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x
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Fluid retention
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Fluid retention
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x
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Parotid gland enlargement
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Parotid gland enlargement
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x
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Anion gap increased
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Anion gap increased
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x
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x
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x
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Haematocrit decreased
|
Haematocrit decreased
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x
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Blood cholesterol increased
|
High cholesterol
|
|
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x
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x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 38 |
Source: | EMA |
---|
Side effects: | 13 |
Source: | FDA |
---|
Side effects: | 18 |
Source: | FDA |
---|
Side effects: | 18 |
Source: | FDA |
---|
Side effects: | 20 |
Source: | FDA |
---|
Side effects: | 34 |
Source: | FDA Structured Product Label |
---|
Side effects: | 34 |
Source: | FDA Structured Product Label |
---|
Side effects: | 39 |
Source: | FDA Structured Product Label |
---|
Side effects: | 40 |
Source: | Health Canada |
---|
Color scheme:
standard – alternative
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|
100%
|
|
|
75%
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50%
|
|
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10%
|
|
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frequent (1% to 100%)
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infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|