Lorazepam
  
Side effects 
	
		
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| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 
| Dizziness | Dizziness | 6.9% |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Asthenia | Asthenia | infrequent, 4.2% |  | x | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Fatigue |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  | 
| Somnolence | Somnolence | 1.54% - 3.75% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Drowsiness |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  | 
| Balance disorder | Unsteadiness | 3.4% |  | x | x | x | x | x |  | x | x | x | x | x | x | x | x | x | 
| Respiratory failure | Respiratory failure | 1.25% - 2.35% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hypoventilation | infrequent, 0.769% - 2.5% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Apnoea | Apnoea | postmarketing — 1.18% - 1.25% |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Headache | Headache | infrequent, 1.18% - 1.25% |  |  | x | x | x | x | x | x | x |  | x | x | x | x | x | x | 
| Hypoxia | Hypoventilation | infrequent, 0.769% - 2.5% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hypoventilation | Hypoventilation | infrequent, 0.769% - 2.5% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hypochromic anaemia | Hypochromic anaemia | 0% - 1.25% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Leukocytosis | Leukocytosis | 0% - 1.25% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Thrombocytosis | Thrombocytosis | 0% - 1.25% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Acidosis | Acidosis | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Ataxia | Ataxia | infrequent |  |  |  |  |  |  | x | x | x |  | x | x | x | x | x | x | 
| Coma | Coma | postmarketing — 0.769% - 1.25% |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Infection | Infection | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Confusional state | Confusional state | infrequent |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Feeling abnormal | Confusional state | infrequent |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Cystitis | Cystitis | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Bladder pain | Cystitis | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cystitis noninfective | Cystitis | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hallucination | Hallucination | infrequent |  | x |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Hyperventilation | Hyperventilation | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Myoclonus | Myoclonus | infrequent |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Nausea | Nausea | infrequent, 0.769% |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Convulsion | Convulsion | postmarketing — 0.769% |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Salivary hypersecretion | Salivary hypersecretion | infrequent |  |  |  |  | x | x |  |  |  |  | x | x | x | x | x | x | 
| Tremor | Tremor | infrequent |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | 
| Vomiting | Vomiting | infrequent, 0.769% |  |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | 
| Chills | Chills | infrequent |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Stupor | Stupor | infrequent, 0% - 1.18% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Depressed level of consciousness | Stupor | infrequent, 0% - 1.18% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| CNS depression NOS |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Agitation | Agitation | infrequent |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Excitement |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Excitability |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Injection site reaction | Injection site reaction | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Liver function test abnormal | Liver function test abnormal | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Blood alkaline phosphatase increased | Phosphatase alkaline increased | infrequent |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Thinking abnormal | Thinking abnormal | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Mental disability | Thinking abnormal | infrequent, 0.769% |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Brain oedema | Brain oedema | postmarketing — 0.769% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hypertension | Hypertension | 0.1% |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hypotension | Hypotension | 0% - 2.35% |  | x |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Amnesia | Amnesia | postmarketing |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Amnesia transient |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  |  |  | 
| Arrhythmia | Arrhythmia | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Coagulopathy | Coagulopathy | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Delirium | Delirium | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Gastrointestinal haemorrhage | Gastrointestinal haemorrhage | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Cardiac arrest | Cardiac arrest | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Atrioventricular block | Block heart | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pulmonary hypertension | Pulmonary hypertension | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Nervousness | Nervousness | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Tension | Nervousness | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Neuroleptic malignant syndrome | Neuroleptic malignant syndrome | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pericardial effusion | Pericardial effusion | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pneumothorax | Pneumothorax | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pulmonary oedema | Pulmonary oedema | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Tachycardia | Tachycardia | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Thrombocytopenia | Thrombocytopenia | postmarketing |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Urinary incontinence | Urinary incontinence | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Ventricular arrhythmia | Ventricular arrhythmia | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pulmonary haemorrhage | Pulmonary haemorrhage | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hepatocellular injury | Hepatocellular injury | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Liver injury | Hepatocellular injury | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Respiratory arrest | Respiratory arrest | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Bradycardia | Bradycardia | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Sleep apnoea syndrome | Obstructive sleep apnea syndrome | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Sleep apnoea syndrome |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Paralysis | Paralysis | postmarketing |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Aggression | Aggression |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Agranulocytosis | Agranulocytosis |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Obstructive airways disorder | Airway obstruction NOS |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Obstructive airways disorder |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Alopecia | Alopecia |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Constipation | Constipation |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Diplopia | Diplopia |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Dysarthria | Dysarthria |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Slurred speech |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  | 
| Osteoarthritis | Dysarthria |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Dermatitis | Rash |  |  |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | 
| Rash | Rash |  |  |  |  |  | x | x | x |  |  | x | x | x | x | x | x | x | 
| Fatigue | Fatigue |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  | 
| Gangrene | Gangrene |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Hostility | Hostility |  |  | x |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Hypersensitivity | Hypersensitivity |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Hyponatraemia | Hyponatraemia |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Body temperature decreased | Body temperature decreased |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Hypothermia | Body temperature decreased |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Inappropriate antidiuretic hormone secretion | Inappropriate antidiuretic hormone secretion |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Irritability | Irritability |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | 
| Jaundice | Jaundice |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Lethargy | Lethargy |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Pain | Pain |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pancytopenia | Pancytopenia |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Psychotic disorder | Psychotic disorder |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Sleep disorder | Sleep disturbance |  |  | x | x | x | x | x | x | x | x |  |  |  |  |  |  |  | 
| Vertigo | Vertigo |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Dry mouth | Dry mouth |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Arterial spasm | Arterial spasm |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Injection site pain | Injection site pain |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Disorientation | Disorientation |  |  |  | x | x | x | x | x | x | x |  |  |  |  |  |  |  | 
| Memory impairment | Memory impairment |  |  |  | x | x |  |  |  | x | x |  |  |  |  |  |  |  | 
| Anterograde amnesia | Anterograde amnesia |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  |  |  | 
| Extrapyramidal disorder | Extrapyramidal symptoms |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Respiratory depression | Respiratory depression |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Pulmonary function test decreased | Respiratory depression |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | x | x | 
| Euphoric mood | Euphoric mood |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Erectile dysfunction | Erectile dysfunction |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Erythema | Redness |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Mania | Mania |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Vision blurred | Vision blurred |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | x | x | 
| Suicidal ideation | Suicidal ideation |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Disinhibition | Disinhibition |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Gastrointestinal disorder | Gastrointestinal symptom NOS |  |  |  | x | x |  |  |  | x | x |  |  |  |  |  |  |  | 
| Application site pain | Application site pain |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Instillation site pain | Application site pain |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Sedation | Oversedation |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Visual impairment | Visual disturbance |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  | 
| Hypersomnia | Hypersomnia |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 10 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 11 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 11 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 14 | 
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		| Source: | medicines.org.au | 
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		| Side effects: | 14 | 
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		| Source: | Medsafe | 
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		| Side effects: | 23 | 
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		| Source: | Health Canada | 
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		| Side effects: | 47 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 47 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 57 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 76 | 
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		| Source: | FDA Structured Product Label | 
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	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |