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Vemurafenib

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
VIIth nerve paralysis VIIth nerve paralysis common x x
Dermatitis Rash postmarketing, 0% - 52% x x x
Rash Rash postmarketing, 0% - 52% x x x
Asthenia Fatigue postmarketing, 2% - 54% x x x
Asthenia postmarketing, 0% - 11% x x x
Fatigue Fatigue postmarketing, 2% - 54% x x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased 0% - 15% x x
Arthralgia Arthralgia postmarketing, 1% - 67% x x x
Musculoskeletal discomfort Arthralgia postmarketing, 1% - 67% x x x
Myalgia postmarketing, 0% - 24% x x x
Photosensitivity reaction Photosensitivity reaction postmarketing, 0% - 49% x x x
Photosensitivity postmarketing x x x
Sunburn postmarketing, 0% - 14% x x x
Dizziness Dizziness postmarketing, common x x
Erythema nodosum Erythema nodosum postmarketing, common x x x
Nervous system disorder Nervous system disorder postmarketing, common x x x
Keratosis pilaris Keratosis pilaris postmarketing, common x x x
Body temperature increased Body temperature increased postmarketing, 1% - 19% x x x
Nausea Nausea postmarketing, 2% - 43% x x x
Pain in extremity Pain in extremity postmarketing, 0% - 18% x x x
Vomiting Vomiting postmarketing, 1% - 26% x x x
Rash maculo-papular Rash maculo-papular postmarketing, 0% - 21% x x x
Pruritus Pruritus postmarketing, 0% - 30% x x x
Alopecia Alopecia postmarketing, 0% - 45% x x x
Back pain Back pain postmarketing, 1% - 11% x x x
Constipation Constipation postmarketing, 0% - 24% x x x
Diarrhoea Diarrhoea postmarketing, 1% - 29% x x x
Headache Headache postmarketing, 0% - 27% x x x
Seborrhoeic keratosis Seborrhoeic keratosis postmarketing, 0% - 14% x x x
Actinic keratosis postmarketing, 0% - 17% x x x
Musculoskeletal pain Musculoskeletal pain postmarketing, 0% - 11% x x x
Oedema peripheral Oedema peripheral postmarketing, 0% - 23% x x x
Myalgia Myalgia postmarketing, 0% - 24% x x x
Hyperkeratosis Hyperkeratosis postmarketing, 0% - 28% x x x
Keratosis postmarketing x x
Decreased appetite Decreased appetite postmarketing, 0% - 21% x x x
Anaphylactic shock Anaphylactic shock postmarketing x
Arthritis Arthritis postmarketing x x x
Basal cell carcinoma Basal cell carcinoma postmarketing x x x
Infection Infection postmarketing x x x
Connective tissue disorder Connective tissue disorder postmarketing x x
Cough Cough postmarketing, 0% - 12% x x x
Cyst Cyst postmarketing x x x
Dysgeusia Dysgeusia postmarketing, 0% - 14% x x x
Eosinophilia Eosinophilia postmarketing x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis postmarketing, common x x x
Eye disorder Eye disorder postmarketing x x x
Folliculitis Folliculitis postmarketing x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x
Cardiac disorder Cardiac disorder postmarketing x x x
Hypersensitivity Hypersensitivity postmarketing x x x
Hypotension Hypotension postmarketing x x
Keratoacanthoma Keratoacanthoma postmarketing x x
Actinic keratosis Actinic keratosis postmarketing, 0% - 17% x x x
Chronic myelomonocytic leukaemia Chronic myelomonocytic leukaemia postmarketing x x x
Mediastinal disorder Mediastinal disorder postmarketing x x x
Malignant melanoma Malignant melanoma postmarketing x
Neoplasm Neoplasm postmarketing x x x
Neuropathy peripheral Neuropathy peripheral postmarketing x x x
Polyp Polyp postmarketing x x x
Retinal vein occlusion Retinal vein occlusion postmarketing x x x
Erythema multiforme Stevens-Johnson syndrome postmarketing, common x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing, common x x x
Erythema Erythema postmarketing, 0% - 14% x x
Uveitis Uveitis postmarketing x x
Angiopathy Angiopathy postmarketing x x x
Vasculitis Vasculitis postmarketing x x x
Skin papilloma Common wart postmarketing x x
Skin papilloma postmarketing, 0% - 30% x x x
Weight decreased Weight decreased postmarketing x x
Dry skin Dry skin postmarketing, 0% - 19% x x x
Malnutrition Malnutrition postmarketing x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue postmarketing, common x x x
Paralysis Nerve paralysis postmarketing x
Metastatic malignant melanoma Metastatic melanoma postmarketing x
Rash generalised Rash generalised postmarketing x
Squamous cell carcinoma of skin Squamous cell carcinoma of skin postmarketing x x
Infestation Infestation NOS postmarketing x x x
Electrocardiogram QT prolonged Electrocardiogram QT corrected interval prolonged postmarketing x x
Rash papular Rash papular postmarketing, 0% - 13% x x x
Atrial fibrillation Atrial fibrillation x x
Neoplasm malignant Neoplasm malignant x
Squamous cell carcinoma Squamous cell carcinoma x
Palmar erythema Palmar erythema x
Sunburn Sunburn postmarketing, 0% - 14% x x x
Hepatotoxicity Hepatotoxicity x
Oropharyngeal squamous cell carcinoma Oropharyngeal squamous cell carcinoma x
Chills Rigors x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Vemurafenib

Side effects:64
Source:FDA Structured Product Label

Vemurafenib / ZELBORAF

Side effects:70
Source:medicines.org.au

vemurafenib / vemurafenib

Side effects:72
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label