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Anthracycline

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01DB02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4
Opportunistic infection Opportunistic infection 27% - 40% x
Malaise Sickness 27% - 40% x
Malaise 1% - 11% x
Asthenia Fatigue 6% - 44% x
Fatigue Fatigue 6% - 44% x
Nausea Nausea 3% - 51% x x x x
Neutropenia Neutropenia 5% - 36% x
Body temperature increased Body temperature increased 5% - 49% x x x
Vomiting Vomiting 2% - 85% x x x x
Arrhythmia Arrhythmia 6-30% x
Diarrhoea Diarrhoea 4% - 34% x x x x
Headache Headache 2% - 23% x
Neuropathy peripheral Neuropathy 1% - 41% x x
Abdominal pain Abdominal pain 3% - 23% x x x
Gastrointestinal pain Abdominal pain 3% - 23% x x x
Decreased appetite Anorexia 2% - 26% x
Hypersensitivity Hypersensitivity 2% - 21% x x x
Cough Cough 0% - 26% x
Dyspnoea Dyspnoea 3% - 23% x
Chills Rigors 0% - 23% x
Chills x x
Alopecia Alopecia 0% - 36% x x
Alopecia reversible x x
Hyperhidrosis Sweating increased 0% - 12% x
Oedema Oedema 1% - 9% x x
Discomfort Malaise 1% - 11% x
Feeling abnormal Malaise 1% - 11% x
Confusional state x
Ill-defined disorder Malaise 1% - 11% x
Depression Depression 0% - 7% x
Stomatitis Stomatitis 0% - 9% x x x
Back pain Back pain 0% - 16% x
Chest pain Chest pain 0% - 9% x
Dizziness Dizziness 0% - 9% x
Syncope x
Constipation Constipation 0% - 18% x
Pruritus Pruritus 0% - 14% x x x
Myalgia Myalgia 0% - 12% x
Musculoskeletal discomfort Myalgia 0% - 12% x
Arthralgia 0% - 7% x
Sinusitis Sinusitis 0% - 8% x
Arthralgia Arthralgia 0% - 7% x
Rhinitis Rhinitis 0% - 12% x
Insomnia Insomnia 0% - 14% x
Influenza like illness Influenza-like symptoms 0% - 5% x
Visual impairment Abnormal vision 0% - 3% x
Proctalgia Rectal tenesmus 0% - 4% x
Rectal tenesmus Rectal tenesmus 0% - 4% x
Anorectal discomfort Rectal tenesmus 0% - 4% x
Amnesia Amnesia x
Anaemia Anaemia x
Angina pectoris Angina pectoris x
Anxiety Anxiety x
Ataxia Ataxia x
Atrial fibrillation Atrial fibrillation x
Atrioventricular block Atrioventricular block x
Bundle branch block Bundle branch block x
Cardiac tamponade Cardiac tamponade x
Cellulitis Cellulitis x x
Infection Infection x
Secondary infection x
Confusional state Confusional state x
Conjunctivitis Conjunctivitis x
Deafness Deafness x
Dysphagia Dysphagia x
Dehydration Dehydration x
Dental caries Dental caries x
Dermatitis contact Dermatitis contact x x
Dysgeusia Dysgeusia x
Dysuria Dysuria x
Ear pain Ear pain x
Oesophagitis Oesophagitis x
Dermatitis Rash x x x
Rash Rash x x x
Extravasation Extravasation x x x x
Flushing Flushing x x
Folliculitis Folliculitis x
Gastritis Gastritis x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Gingival bleeding Gingival bleeding x
Hallucination Hallucination x
Cardiac arrest Cardiac arrest x
Cardiac disorder Cardiac disorder x
Cardiac failure Cardiac failure x
Cardiac failure congestive Cardiac failure congestive x x x
Haemoptysis Haemoptysis x
Haemorrhoids Haemorrhoids x
Hepatomegaly Hepatomegaly x
Hiccups Hiccups x
Hypertension Hypertension x
Pulmonary hypertension Pulmonary hypertension x
Leukopenia Leukopenia x
Melaena Melaena x
Meningitis Meningitis x
Hypertonia Hypertonia x
Myelodysplastic syndrome Myelodysplastic syndrome x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Myocarditis Myocarditis x
Necrosis Necrosis x x x x
Nocturia Nocturia x
Pain Pain x
Palpitations Palpitations x
Pericardial effusion Pericardial effusion x x
Pericarditis Pericarditis x
Polyuria Polyuria x
Urine output increased Polyuria x
Renal failure Renal failure x
Renal impairment x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Convulsion Convulsion x
Splenomegaly Splenomegaly x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Tachycardia Tachycardia x
Sinus tachycardia Sinus tachycardia x
Supraventricular tachycardia Supraventricular tachycardia x
Thirst Thirst x
Thrombocytopenia Thrombocytopenia x
Thrombophlebitis Thrombophlebitis x x
Tinnitus Tinnitus x
Tremor Tremor x
Ulcer Ulcer x x
Erythema Erythema x
Urticaria Urticaria x x
Welts x
Viral infection Viral infection x
Dry mouth Dry mouth x
Mood swings Mood swings x
Affect lability Mood swings x
Hepatic function abnormal Hepatic function abnormal x
Ventricular extrasystoles Ventricular extrasystoles x
Injection site inflammation Injection site inflammation x
Pancytopenia Bone marrow depression x
Myelosuppression x x x x
Eye pain Eye pain x
Dry skin Dry skin x
Skin hyperpigmentation Skin hyperpigmentation x x
Chest discomfort Chest tightness x
Increased appetite Increased appetite x
Thinking abnormal Thinking abnormal x
Mental disability Thinking abnormal x
Nail disorder Nail changes x
Lung infiltration Lung infiltration x
Induration Induration x x
Mucosal inflammation Mucosal inflammation x
Anaphylactic shock Anaphylactoid reaction x
Anaphylactoid reaction Anaphylactoid reaction x
Hyperpyrexia Hyperpyrexia x
Agitation Hyperkinesia x
Hyperkinesia Hyperkinesia x
Lymphadenopathy Lymphadenopathy x
Electrocardiogram abnormal Electrocardiogram abnormal x
Gait disturbance Gait disturbance x
Menopausal symptoms Hot flush x
Hot flush Hot flush x
Blood uric acid increased Hyperuricaemia x x
Hyperuricaemia Hyperuricaemia x x
Febrile neutropenia Febrile neutropenia x
Local reaction Local reaction x
Electrocardiogram change Electrocardiogram change x
Rash macular Red blotches x
Cardiotoxicity Cardiotoxicity x x x
Acute cardiac toxicity x
Cardiomyopathy Cardiomyopathy x x x
Liver disorder Hepatic impairment x
Renal impairment Renal impairment x
Recall phenomenon Radiation recall reaction (dermatologic) x
Somnolence Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Daunorubicin

Side effects:36
Source:BC Cancer

DAUNORUBICIN

Side effects:20
Source:FDA Structured Product Label

Daunorubicin hydrochloride / DAUNORUBICIN INJECTION

Side effects:40
Source:medicines.org.au

DAUNORUBICIN

Side effects:102
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label