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Axitinib

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Diarrhoea Diarrhoea 7% - 55% x x
Hypertension Hypertension 11% - 40% x x
Asthenia Fatigue 5% - 39% x x
Asthenia 3% - 21% x
Fatigue Fatigue 5% - 39% x x
Blood creatinine increased Creatinine increased 0% - 55% x x
Hypocalcaemia Hypocalcaemia 1% - 59% x
Haemoglobin decreased Haemoglobin decreased 1% - 52% x
Decreased appetite Decreased appetite 4% - 34% x x
Blood alkaline phosphatase increased Phosphatase alkaline increased 1% - 34% x x
Lipase increased Lipase increased 3% - 46% x x
Hypophosphataemia Hypophosphataemia 2% - 49% x
Amylase increased Amylase increased 2% - 33% x x
Hyperglycaemia Hyperglycaemia 2% - 28% x
Nausea Nausea 1% - 32% x x
Alanine aminotransferase increased Alanine aminotransferase increased 1% - 22% x x
Weight decreased Weight decreased 1% - 25% x x
Constipation Constipation 1% - 20% x x
Aspartate aminotransferase increased Aspartate aminotransferase increased 1% - 25% x x
Vomiting Vomiting 1% - 24% x x
Dizziness Dizziness 9% x x
Dermatitis Rash 1% - 32% x x
Rash Rash 1% - 32% x x
Cough Cough 1% - 17% x x
Abdominal pain upper Abdominal pain upper 8% x x
Hypoalbuminaemia Hypoalbuminaemia 1% - 18% x
Dyspnoea Dyspnoea 3% - 15% x x
Hyponatraemia Hyponatraemia 2% - 13% x
Platelet count decreased Platelet count decreased 0% - 15% x
Hypernatraemia Hypernatraemia 1% - 17% x
Pain in extremity Pain in extremity 1% - 14% x x
Myalgia Myalgia 7% x x
Musculoskeletal discomfort Myalgia 7% x x
Arthralgia 1% - 15% x x
Dysphonia Dysphonia 0% - 31% x x
Abdominal pain Abdominal pain 1% - 14% x x
Gastrointestinal pain Abdominal pain 1% - 14% x x
Arthralgia Arthralgia 1% - 15% x x
Hyperkalaemia Hyperkalaemia 3% - 15% x x
Stomatitis Stomatitis 1% - 15% x x
Mucosal inflammation Mucosal inflammation 1% - 15% x x
Dehydration Dehydration 6% x x
Epistaxis Epistaxis 6% - 7.8% x x
Headache Headache 0% - 14% x x
White blood cell count decreased White blood cell count decreased 0% - 16% x
Proteinuria Proteinuria 2% - 11% x x
Protein urine present Proteinuria 2% - 11% x x
Dry skin Dry skin 0% - 11% x x
Hypoglycaemia Hypoglycaemia 1% - 11% x
Hypothyroidism Hypothyroidism 0% - 19% x x
Anaemia Anaemia 4% x x
Dysgeusia Dysgeusia 0% - 11% x x
Haemorrhoids Haemorrhoids 4% x x
Pruritus Pruritus 0% - 12% x x
Glossodynia Glossodynia 3% x x
Haematuria Haematuria 3% - 3.6% x x
Tinnitus Tinnitus 3% x x
Alopecia Alopecia 0% - 32% x x
Haemoptysis Haemoptysis 2% - 2.5% x x
Pulmonary embolism Pulmonary embolism 2% - 2.2% x x
Rectal haemorrhage Rectal haemorrhage 2% - 2.2% x x
Myocardial infarction Myocardial infarction 1.4% x
Acute coronary syndrome Myocardial infarction 1.4% x
Erythema Erythema 0% - 10% x x
Gingival bleeding Gingival bleeding 1.1% x
Transient ischaemic attack Transient ischaemic attack 0.8% - 1% x x
Dyspepsia Dyspepsia 0% - 10% x x
Polycythaemia Polycythaemia 1% x x
Thrombosis Thrombosis 0.6% - 1% x x
Deep vein thrombosis Deep vein thrombosis 0.6% - 1% x x
Cerebrovascular accident Cerebrovascular accident 0.6% x
Anal fistula Anal fistula 0.6% x
Gastric haemorrhage Gastric haemorrhage 0.6% x
Fistula Fistula 0.3% x x
Lower gastrointestinal haemorrhage Lower gastrointestinal haemorrhage 0.3% x
Gastrointestinal perforation Gastrointestinal perforation 0.3% x x
Cerebral haemorrhage Cerebral haemorrhage 0.3% x
Neoplasm malignant Neoplasm malignant x
Connective tissue disorder Connective tissue disorder x
Endocrine disorder Endocrine disorder x
Flatulence Flatulence x
Gastrointestinal disorder Gastrointestinal disorder x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Cardiac failure Cardiac failure x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hypercalcaemia Hypercalcaemia x x
Hypertensive crisis Hypertensive crisis x
Hyperthyroidism Hyperthyroidism x
Renal failure acute Renal failure acute x
Leukopenia Leukopenia x
Mediastinal disorder Mediastinal disorder x
Nervous system disorder Nervous system disorder x
Neutropenia Neutropenia x
Renal failure Renal failure x
Retinal vein occlusion Retinal vein occlusion x x
Thrombocytopenia Thrombocytopenia x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x
Acute myocardial infarction Acute myocardial infarction x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Brain cancer metastatic Brain cancer metastatic x
Metastases to central nervous system Brain cancer metastatic x
Hepatobiliary disease Hepatobiliary disease x
Thyroid disorder Dysfunction thyroid x x
Haemoglobin increased Haemoglobin increased x
Blood thyroid stimulating hormone increased Thyrotropin high x
Embolism Thromboembolic event x
Liver disorder Hepatic impairment x
Oropharyngeal pain Oropharyngeal pain x
Posterior reversible encephalopathy syndrome Posterior reversible encephalopathy syndrome x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

AXITINIB

Side effects:71
Source:FDA Structured Product Label

axitinib / axitinib

Side effects:91
Source:EMA

Color scheme:

standard – alternative

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