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Actinomycin D

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01DA01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Diarrhoea Diarrhoea 30% x x x
Stomatitis Stomatitis 30% x
Abdominal pain Abdominal pain x x
Gastrointestinal pain Abdominal pain x x
Agranulocytosis Agranulocytosis x x
Alopecia Alopecia x x x
Anaemia Anaemia x x
Aplastic anaemia Aplastic anaemia x x
Decreased appetite Anorexia x x x
Ascites Ascites x x x
Coagulopathy Coagulopathy x x
Cheilitis Cheilitis x x
Infection Infection x x
Muscle contracture Muscle contracture x x
Dysphagia Dysphagia x x
Oedema Oedema x
Toxic epidermal necrolysis Toxic epidermal necrolysis x
Erythema multiforme Erythema multiforme x
Stevens-Johnson syndrome x
Oesophagitis Oesophagitis x x
Extravasation Extravasation x x x
Asthenia Fatigue x x
Fatigue Fatigue x x
Body temperature increased Body temperature increased x x x
Flushing Flushing x
Folliculitis Folliculitis x
Venoocclusive liver disease Venoocclusive liver disease x x
Hepatitis Hepatitis x x
Hepatomegaly Hepatomegaly x x x
Hypersensitivity Hypersensitivity x
Hypocalcaemia Hypocalcaemia x x x
Lethargy Lethargy x x
Leukopenia Leukopenia x x
Multi-organ failure Multi-organ failure x x
Nausea Nausea x x x
Necrosis Necrosis x
Neutropenia Neutropenia x x
Pain Pain x
Pancytopenia Pancytopenia x x
Myelosuppression x
Pharyngitis Pharyngitis x x
Phlebitis Phlebitis x
Pneumonia Pneumonia x
Proctitis Proctitis x x
Radiation injury Radiation injury x
Stevens-Johnson syndrome Stevens-Johnson syndrome x
Mouth ulceration Ulcerative stomatitis x x
Thrombocytopenia Thrombocytopenia x x x
Ulcer Ulcer x x
Erythema Erythema x x
Vomiting Vomiting x x x
Chills Chills x
Hepatic failure Hepatic failure x x
Growth retardation Growth retardation x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Malaise Malaise x x
Discomfort Malaise x x
Feeling abnormal Malaise x x
Ill-defined disorder Malaise x x
Myalgia Myalgia x x
Musculoskeletal discomfort Myalgia x x
Hepatotoxicity Hepatotoxicity x
Sepsis Sepsis x
Rash Eruption x x
Epidermolysis Epidermolysis x
Febrile neutropenia Febrile neutropenia x x
Reticulocytopenia Reticulocytopenia x
Neutropenic sepsis Neutropenic sepsis x
Liver function test abnormal Raised liver function tests x
Venoocclusive disease Venoocclusive disease x
Recall phenomenon Radiation recall reaction (dermatologic) x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Dactinomycin

Side effects:25
Source:BC Cancer

DACTINOMYCIN / COSMEGEN

Side effects:41
Source:Health Canada

DACTINOMYCIN

Side effects:51
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label