Search results :


More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L04AA02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
Body temperature increased Body temperature increased postmarketing, 77% - 90% x
Chills Chills 43% - 59% x
Rigors 8% x
Bacterial infection Bacterial infection 47% x
Diarrhoea Diarrhoea 14% - 37% x
Nausea Nausea 19% - 32% x
Hypotension Hypotension 25% x
Vomiting Vomiting 19% - 25% x
Fungal infection Fungal infection 21% x
Headache Headache postmarketing, 11% - 44% x
Dyspnoea Dyspnoea 16% - 21% x
Tachycardia Tachycardia 10% - 26% x
Chest pain Chest pain 14% x
Dermatitis Rash 14% x
Rash Rash 14% x
Hypertension Hypertension 8% - 19% x
Tremor Tremor 13% - 14% x
Oedema Oedema 12% x
Asthenia Asthenia 10% x
Fatigue 9% x
Breath sounds abnormal Abnormal chest sounds NOS 10% x
Wheezing Wheezing 6% - 13% x
Fatigue Fatigue 9% x
Musculoskeletal stiffness Neck stiffness postmarketing, 14% x
Stiffness postmarketing x
Nuchal rigidity Neck stiffness postmarketing, 14% x
Arthralgia Arthralgia 7% x
Musculoskeletal discomfort Arthralgia 7% x
Myalgia 1% x
Hyperventilation Hyperventilation 7% x
Leukopenia Leukopenia 7% x
Pruritus Pruritus 7% x
Vasodilation procedure Vasodilation 7% x
Hyperhidrosis Sweating increased 7% x
Confusional state Confusional state 6% x
Feeling abnormal Confusional state 6% x
Malaise 5% x
Dizziness Dizziness 6% x
Lethargy Lethargy 6% x
Pain Pain postmarketing, 6% - 9% x
Ache postmarketing x
Nervousness Nervousness 5% x
Tension Nervousness 5% x
Malaise Malaise 5% x
Discomfort Malaise 5% x
Ill-defined disorder Malaise 5% x
Decreased appetite Anorexia 4% x
Arrhythmia Arrhythmia 4% x
Bradycardia Bradycardia 4% x
Depression Depression 3% x
Anaemia Anaemia 2% x
Pulmonary oedema Pulmonary oedema 2% x
Thrombocytopenia Thrombocytopenia 2% x
Rash erythematous Rash erythematous 2% x
Vascular occlusion Vascular occlusion 2% x
Somnolence Somnolence 2% x
Leukocytosis Leukocytosis 1% x
Meningitis Meningitis 1% x
Pneumonia Pneumonia 1% x
Tinnitus Tinnitus 1% x
Photophobia Photophobia postmarketing, 1% - 10% x
Myalgia Myalgia 1% x
Hypoxia Hypoxia 1% x
Convulsion Convulsion postmarketing, 1% x
Aplastic anaemia Aplastic anaemia postmarketing x
Aphasia Aphasia postmarketing x
Arthritis Arthritis postmarketing x
Brain oedema Edema cerebral postmarketing x
Neoplasm malignant Neoplasm malignant postmarketing x
Carcinoma x
Cardiovascular disorder Cardiovascular disorder postmarketing x
Central nervous system infection Central nervous system infection postmarketing x
Transient ischaemic attack Transient ischaemic attack postmarketing x
Deafness Deafness postmarketing x
Diplopia Diplopia postmarketing x
Disseminated intravascular coagulation Disseminated intravascular coagulation postmarketing x
Encephalitis Encephalitis postmarketing x
Cerebritis postmarketing x
Flushing Flushing postmarketing x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x
Hepatitis Hepatitis postmarketing x
Hepatitis B Hepatitis B postmarketing x
Hepatitis C Hepatitis C postmarketing x
Nephropathy Nephropathy postmarketing x
Lymphoma Lymphoma postmarketing x
Non-Hodgkin's lymphoma Lymphoma postmarketing x
Meningitis aseptic Meningitis aseptic postmarketing x
Musculoskeletal disorder Musculoskeletal disorder postmarketing x
Myoclonus Myoclonus postmarketing x
Neutropenia Neutropenia postmarketing x
Otitis media Otitis media postmarketing x
Pancytopenia Pancytopenia postmarketing x
Optic neuritis Papilloedema postmarketing x
Papilloedema Papilloedema postmarketing x
Paresis Paresis postmarketing x
Neuropathy peripheral Neuropathy peripheral postmarketing x
Renal failure Renal failure postmarketing x
Renal impairment postmarketing x
Acute respiratory distress syndrome Acute respiratory distress syndrome postmarketing x
Shock Shock postmarketing x
Splenomegaly Splenomegaly postmarketing x
Status epilepticus Status epilepticus postmarketing x
Erythema multiforme Stevens-Johnson syndrome postmarketing x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x
Cerebrovascular accident Cerebrovascular accident postmarketing x
Thrombosis Thrombosis postmarketing x
Erythema Erythema postmarketing x
Urticaria Urticaria postmarketing x
Vertigo Vertigo postmarketing x
Hepatitis viral Hepatitis viral postmarketing x
Viral infection Viral infection postmarketing x
Stupor Stupor postmarketing x
Depressed level of consciousness Stupor postmarketing x
Obnubilation postmarketing x
Agitation Agitation postmarketing x
Haemorrhage intracranial Haemorrhage intracranial postmarketing x
Hyperreflexia Hyperreflexia postmarketing x
Respiratory arrest Respiratory arrest postmarketing x
Microangiopathic haemolytic anaemia Microangiopathic haemolytic anaemia postmarketing x
Asterixis Asterixis postmarketing x
Skin exfoliation Skin exfoliation postmarketing x
Intestinal infarction Intestinal infarction postmarketing x
Azotaemia Azotaemia postmarketing x
Left ventricular dysfunction Left ventricular dysfunction postmarketing x
Quadriparesis Quadriparesis postmarketing x
VIth nerve paralysis VIth nerve paralysis postmarketing x
Cognitive disorder Cognitive impairment postmarketing x
Vision blurred Vision blurred postmarketing x
Dyskinesia Movements involuntary postmarketing x
Blindness Blindness postmarketing x
Paralysis Paralysis postmarketing x
Brain herniation Brain herniation postmarketing x
Cytokine release syndrome Cytokine release syndrome postmarketing x
Haemodynamic instability Haemodynamic instability postmarketing x
Respiratory failure Respiratory failure postmarketing x
Renal impairment Renal impairment postmarketing x
Adenocarcinoma Adenocarcinoma x
Obstructive airways disorder Airway obstruction NOS x
Anaphylactic shock Anaphylactic shock x
Angina pectoris Angina pectoris x
Angioedema Angioedema x
Anuria Anuria x
Apnoea Apnoea x
Mental disorder Mental disorder x
Coagulopathy Coagulopathy x
Renal cell carcinoma Renal cell carcinoma x
Coma Coma x
Conjunctivitis Conjunctivitis x
Cytomegalovirus infection Cytomegalovirus infection x
Eosinophilia Eosinophilia x
Epilepsy Epilepsy x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Glomerulonephritis Glomerulonephritis x
Hallucination Hallucination x
Cardiac arrest Cardiac arrest x
Cardiac failure Cardiac failure x
Herpes virus infection Herpes NOS x
Herpes simplex Herpes simplex x
Hyperplasia Hyperplasia x
Hypersensitivity Hypersensitivity x
Keratoacanthoma Keratoacanthoma x
Laryngospasm Laryngospasm x
Leukaemia Leukaemia x
Lymphopenia Lymphopenia x
Lymphoproliferative disorder Lymphoproliferative disorder x
X-linked lymphoproliferative syndrome Lymphoproliferative disorder x
Malignant melanoma Malignant melanoma x
Plasma cell myeloma Plasma cell myeloma x
Plasmacytoma Plasma cell myeloma x
Hypotonia Hypotonia x
Muscle relaxant therapy Hypotonia x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Tubulointerstitial nephritis Nephritis interstitial x
Oliguria Oliguria x
Psychotic disorder Psychotic disorder x
Paranoia x
Serum sickness Serum sickness x
Vasculitis Vasculitis x
B-cell lymphoma B-cell lymphoma x
Encephalopathy Encephalopathy x
Mood swings Mood swings x
Affect lability Mood swings x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Malnutrition Malnutrition x
Cholangiocarcinoma Cholangiocarcinoma x
Lip swelling Lip swelling x
Sepsis Sepsis x
Lymphadenopathy Lymphadenopathy x
Fluid overload Fluid overload x
Breast cancer Carcinoma breast x
Herpes zoster Varicella zoster x
Autonomic neuropathy Unspecified disorder of autonomic nervous system x
Paranoia Paranoia x
Hepatic cancer Hepatocellular carcinoma x
Hepatocellular carcinoma Hepatocellular carcinoma x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:175
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label