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Dexrazoxane

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: V03AF02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Alopecia Alopecia 94% - 100% 97% - 98% x x x x x x
Nausea Nausea 51% - 82% 60% - 84% x x x x x x
Malaise Malaise 48% - 62% 55% - 58% x x x x
Discomfort Malaise 48% - 62% 55% - 58% x x x x
Feeling abnormal Malaise 48% - 62% 55% - 58% x x x x
Ill-defined disorder Malaise 48% - 62% 55% - 58% x x x x
Asthenia Fatigue 48% - 61% 55% - 58% x x x x x x
Fatigue Fatigue 48% - 61% 55% - 58% x x x x x x
Vomiting Vomiting 42% - 63% 49% - 72% x x x x x x
Decreased appetite Anorexia 27% - 50% 38% - 47% x x x x x
Decreased appetite x
Stomatitis Stomatitis 26% - 36% 28% - 41% x x x x x x
Body temperature increased Body temperature increased 18% - 35% 18% - 29% x x x x x x
Infection Infection 19% - 23% 18% - 21% x x x x x x
Diarrhoea Diarrhoea 7% - 22% 7% - 24% x x x x x x
Sepsis Sepsis 9% - 31% 9% - 14% x x x x
Neurotoxicity Neurotoxicity 5% - 17% 5% - 13% x x x x
Pain Pain 0% - 13% 0% - 3% x x x x x
Dysphagia Dysphagia 0% - 8% 5% - 10% x x x x
Phlebitis Phlebitis 3% - 6% 3% - 5% x x x x x
Oesophagitis Oesophagitis 3% - 6% 4% - 7% x x x x
Erythema Erythema 2% - 5% 2% - 4% x x x x
Extravasation Extravasation 1% - 3% 1% - 2% x x x
Haemorrhage Haemorrhage 1% - 3% 1% - 2% x x x x
Haemoglobin Haemorrhage 1% - 3% 1% - 2% x x x x
Urticaria Urticaria 0% - 4% 0% - 2% x x x x
Cardiac failure congestive Cardiac failure congestive 1% x
Abdominal pain Abdominal pain x
Gastrointestinal pain Abdominal pain x
Agranulocytosis Agranulocytosis x x x x x
Anaemia Anaemia x
Mental disorder Mental disorder x
Breast disorder Breast disorder x
Neoplasm malignant Neoplasm malignant x x x
Connective tissue disorder Connective tissue disorder x x
Constipation Constipation x
Cough Cough x
Depression Depression x
Dizziness Dizziness x x
Syncope x
Dyspnoea Dyspnoea x x
Gastrointestinal disorder Gastrointestinal disorder x x
Headache Headache x
Cardiac disorder Cardiac disorder x
Leukopenia Leukopenia x x x x
Mediastinal disorder Mediastinal disorder x x
Nervous system disorder Nervous system disorder x x
Neutropenia Neutropenia x x
Pneumonia Pneumonia x x
Pruritus Pruritus x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Thrombocytopenia Thrombocytopenia x x x x x x x
Tremor Tremor x
Angiopathy Angiopathy x x
Weight decreased Weight decreased x
Dry mouth Dry mouth x
Oedema peripheral Oedema peripheral x x
Blood creatinine increased Creatinine increased x
Injection site swelling Injection site swelling x
Injection site reaction Injection site reaction x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased 0% x
Injection site pain Injection site pain x x
Blood alkaline phosphatase increased Phosphatase alkaline increased 0% x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Haemoglobin decreased Haemoglobin decreased 0% x
Malnutrition Malnutrition x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Myalgia Myalgia x
Musculoskeletal discomfort Myalgia x
Disease progression Disease progression x x
Sensory loss Sensory loss x
Blood bilirubin increased Blood bilirubin increased 0% x
Platelet count decreased Platelet count decreased 0% x
Post procedural infection Postoperative infection x x
Injection site induration Injection site induration x
Injection site phlebitis Injection site phlebitis x x
Hypercalcaemia Ca++ increased x
Febrile neutropenia Febrile neutropenia x x
White blood cell count decreased White blood cell count decreased x
Infestation Infestation NOS x x
Injection site erythema Injection site erythema x
Venous thrombosis limb Venous thrombosis limb x
Pancytopenia Myelosuppression x x
Hyponatraemia Sodium decreased x
Cardiotoxicity Cardiotoxicity x x
Infusion site pain Infusion site burning x
Insomnia Insomnia x
Wound complication Wound complication x
Neutropenic infection Neutropenic infection x
Thrombophlebitis superficial Thrombophlebitis superficial x
Somnolence Somnolence x
Vaginal haemorrhage Vaginal haemorrhage x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

dexrazoxane for injection / Zinecard

Side effects:5
Source:FDA

Dexrazoxane

Side effects:23
Source:BC Cancer

dexrazoxane / ZINECARD

Side effects:24
Source:FDA

DEXRAZOXANE

Side effects:26
Source:FDA Structured Product Label

DEXRAZOXANE

Side effects:26
Source:FDA Structured Product Label

dexrazoxane / dexrazoxane hydrochloride

Side effects:46
Source:EMA

DEXRAZOXANE HYDROCHLORIDE / TOTECT

Side effects:49
Source:FDA

Color scheme:

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