Cyproterone acetate
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
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Data for drug
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Placebo
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Labels
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1
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2
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3
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4
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5
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Asthenia
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Fatigue
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very rare — very common
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x
|
x
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x
|
x
|
x
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Asthenia
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|
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|
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x
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Fatigue
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Fatigue
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very rare — very common
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|
x
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x
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x
|
x
|
x
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Lassitude
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common
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|
x
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|
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x
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Weight increased
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Weight increased
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very rare — very common
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x
|
x
|
x
|
x
|
x
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Gynaecomastia
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Gynaecomastia
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very rare, common
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|
x
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x
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x
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x
|
x
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Headache
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Headache
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very rare, common
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|
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x
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x
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x
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x
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Breast pain
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Breast pain
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very rare, common
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|
|
x
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x
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x
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|
Nausea
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Nausea
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very rare, common
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x
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x
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x
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x
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Hyperhidrosis
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Sweating
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common
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|
x
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|
x
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x
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Sweating increased
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x
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Agitation
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Agitation
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common
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|
x
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x
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x
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Tenderness
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Tenderness
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common
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x
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x
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x
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x
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Breast tenderness
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Breast tenderness
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very rare, common
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x
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x
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x
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x
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Fluid retention
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Fluid retention
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common
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x
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|
|
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Menstruation irregular
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Menstruation irregular
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very rare — common
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x
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x
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x
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Dysmenorrhoea
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Dysmenorrhoea
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uncommon
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|
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x
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x
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x
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Libido increased
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Libido increased
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very rare, uncommon
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x
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x
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x
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x
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Disturbance in sexual arousal
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Libido increased
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very rare, uncommon
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x
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x
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x
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x
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Libido decreased
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x
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x
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x
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Osteoporosis
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Osteoporosis
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uncommon
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x
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x
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x
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x
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x
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Sleep disorder
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Sleep disturbance
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very rare, uncommon
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x
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x
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x
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Tachycardia
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Tachycardia
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very rare, uncommon
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x
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x
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x
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x
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Skin discolouration
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Skin discolouration
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uncommon
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|
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x
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x
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x
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x
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Skin striae
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Skin striae
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uncommon
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|
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x
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x
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x
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Vaginal discharge
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Vaginal discharge
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uncommon
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x
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x
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x
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Menopausal symptoms
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Hot flush
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very rare — common
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x
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x
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x
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x
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Hot flush
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Hot flush
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very rare — common
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x
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x
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x
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x
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Hypersensitivity
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Hypersensitivity
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very rare — uncommon
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x
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x
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x
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x
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x
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Galactorrhoea
|
Galactorrhoea
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very rare — uncommon
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x
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x
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x
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x
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x
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Dyspnoea
|
Dyspnoea
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rare
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x
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x
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x
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Dermatitis
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Rash
|
very rare — uncommon
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x
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x
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x
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x
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x
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Rash
|
Rash
|
very rare — uncommon
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x
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x
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x
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x
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x
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Hepatitis
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Hepatitis
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very rare — common
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x
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x
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x
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x
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x
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Jaundice
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Jaundice
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rare, common
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x
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x
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x
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x
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x
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Nodule
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Nodule
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rare
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x
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Hepatic failure
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Hepatic failure
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very rare — common
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x
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x
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x
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x
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x
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Rash generalised
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Rash generalised
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rare
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x
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Hepatic neoplasm
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Hepatic neoplasm
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very rare
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x
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x
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x
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Intra-abdominal haemorrhage
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Intra-abdominal haemorrhage
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very rare
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x
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x
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x
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Acne
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Acne vulgaris
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x
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Alopecia
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Alopecia
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x
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Anaemia
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Anaemia
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x
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x
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x
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x
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Haemolytic anaemia
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Haemolytic anaemia
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x
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Hypochromic anaemia
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Hypochromic anaemia
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x
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x
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Decreased appetite
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Anorexia
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x
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Aphasia
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Aphasia
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x
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Ascites
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Ascites
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x
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Asthma
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Asthma
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x
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Azoospermia
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Azoospermia
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|
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x
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Mental disorder
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Mental disorder
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x
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x
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x
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Breast disorder
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Breast disorder
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x
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x
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Cardiovascular disorder
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Cardiovascular disorder
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x
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x
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x
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Coma
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Coma
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x
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Connective tissue disorder
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Connective tissue disorder
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|
|
x
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|
x
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x
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Constipation
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Constipation
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x
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Cyst
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Cyst
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x
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Libido decreased
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Libido decreased
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x
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|
x
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x
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Dermatitis exfoliative
|
Dermatitis exfoliative
|
|
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x
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Scleroderma
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Scleroderma
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|
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x
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Diabetes mellitus
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Diabetes mellitus
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x
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Diarrhoea
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Diarrhoea
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x
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Dizziness
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Dizziness
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x
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Syncope
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|
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x
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Dyspepsia
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Dyspepsia
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x
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Ear disorder
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Ear disorder
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|
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x
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Eczema
|
Eczema
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|
|
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x
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Oedema
|
Oedema
|
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|
|
|
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x
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Endocrine disorder
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Endocrine disorder
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|
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x
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Erythema nodosum
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Erythema nodosum
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|
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x
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Body temperature increased
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Body temperature increased
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x
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Gastrointestinal disorder
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Gastrointestinal disorder
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|
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x
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x
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Glossitis
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Glossitis
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x
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Cardiac failure
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Cardiac failure
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|
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x
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Haematuria
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Haematuria
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x
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Hemiplegia
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Hemiplegia
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|
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x
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Haemorrhage
|
Haemorrhage
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x
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Haemoglobin
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Haemorrhage
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x
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Coma hepatic
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Coma hepatic
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x
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Hepatomegaly
|
Hepatomegaly
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|
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x
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Hernia
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Hernia
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|
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x
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Hirsutism
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Hirsutism
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|
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x
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Hypercalcaemia
|
Hypercalcaemia
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|
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x
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Hyperglycaemia
|
Hyperglycaemia
|
|
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|
x
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Hypernatraemia
|
Hypernatraemia
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|
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x
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Nodular regenerative hyperplasia
|
Nodular regenerative hyperplasia
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|
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x
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Hyperventilation
|
Hyperventilation
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x
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Hypotension
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Hypotension
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x
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Immune system disorder
|
Immune system disorder
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|
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x
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x
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x
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Infertility
|
Infertility
|
|
|
x
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x
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|
x
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Jaundice cholestatic
|
Jaundice cholestatic
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|
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x
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Leukocytosis
|
Leukocytosis
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|
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|
|
|
x
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Leukopenia
|
Leukopenia
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x
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Hepatic cirrhosis
|
Hepatic cirrhosis
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|
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|
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x
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Mediastinal disorder
|
Mediastinal disorder
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|
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x
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|
x
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x
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Meningioma
|
Meningioma
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|
|
x
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|
x
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x
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Myocardial infarction
|
Myocardial infarction
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|
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|
|
|
|
x
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Acute coronary syndrome
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Myocardial infarction
|
|
|
|
|
|
|
x
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Neoplasm
|
Neoplasm
|
|
|
x
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|
x
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x
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Optic atrophy
|
Optic atrophy
|
|
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|
|
|
|
x
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Optic neuritis
|
Optic neuritis
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|
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|
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|
x
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Pancreatitis
|
Pancreatitis
|
|
|
|
|
|
|
x
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Personality disorder
|
Personality disorder
|
|
|
|
|
|
|
x
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Phlebitis
|
Phlebitis
|
|
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|
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|
|
x
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Polyp
|
Polyp
|
|
|
x
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|
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Pruritus
|
Pruritus
|
|
|
|
|
|
|
x
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Pulmonary embolism
|
Pulmonary embolism
|
|
|
|
|
|
|
x
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Pulmonary fibrosis
|
Pulmonary fibrosis
|
|
|
|
|
|
|
x
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Renal failure
|
Renal failure
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|
|
|
|
|
|
x
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Retinal disorder
|
Retinal disorder
|
|
|
|
|
|
|
x
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Shock
|
Shock
|
|
|
|
|
|
|
x
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Syncope
|
|
|
|
|
|
|
x
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Cerebrovascular accident
|
Cerebrovascular accident
|
|
|
|
|
|
|
x
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Syncope
|
Syncope
|
|
|
|
|
|
|
x
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Loss of consciousness
|
Syncope
|
|
|
|
|
|
|
x
|
Thrombocytopenia
|
Thrombocytopenia
|
|
|
|
|
|
|
x
|
Thrombophlebitis
|
Thrombophlebitis
|
|
|
|
|
|
|
x
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Thrombosis
|
Thrombosis
|
|
|
|
|
|
|
x
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Pollakiuria
|
Pollakiuria
|
|
|
|
|
|
|
x
|
Urticaria
|
Urticaria
|
|
|
|
|
|
|
x
|
Uterine haemorrhage
|
Uterine haemorrhage
|
|
|
|
|
|
|
x
|
Angiopathy
|
Angiopathy
|
|
|
x
|
|
|
|
|
Vascular headache
|
Vascular headache
|
|
|
|
|
|
|
x
|
Vomiting
|
Vomiting
|
|
|
|
|
|
|
x
|
Weight decreased
|
Weight decreased
|
|
|
|
|
x
|
x
|
x
|
Normochromic normocytic anaemia
|
Normocytic anemia
|
|
|
|
|
|
|
x
|
Encephalopathy
|
Encephalopathy
|
|
|
|
|
|
|
x
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Chills
|
Chills
|
|
|
|
|
|
|
x
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Blood creatinine increased
|
Creatinine increased
|
|
|
|
|
|
|
x
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Crystalluria
|
Urate crystalluria
|
|
|
|
|
|
|
x
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Injection site reaction
|
Injection site reaction
|
|
|
|
|
|
|
x
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Liver function test abnormal
|
Liver function test abnormal
|
|
|
|
|
|
|
x
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Hepatic necrosis
|
Hepatic necrosis
|
|
|
|
|
|
|
x
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Aspartate aminotransferase increased
|
Aspartate aminotransferase increased
|
|
|
|
|
|
|
x
|
Alanine aminotransferase increased
|
Alanine aminotransferase increased
|
|
|
|
|
|
|
x
|
Uterine leiomyoma
|
Uterine fibroids enlarged
|
|
|
|
|
|
|
x
|
Accommodation disorder
|
Accommodation disorder
|
|
|
|
|
|
|
x
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Retinal vascular disorder
|
Retinal vascular disorder
|
|
|
|
|
|
|
x
|
Malnutrition
|
Malnutrition
|
|
|
x
|
|
x
|
x
|
|
Photosensitivity reaction
|
Photosensitivity reaction
|
|
|
|
|
|
|
x
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
|
|
x
|
x
|
|
Malaise
|
Malaise
|
|
|
|
|
|
|
x
|
Discomfort
|
Malaise
|
|
|
|
|
|
|
x
|
Feeling abnormal
|
Malaise
|
|
|
|
|
|
|
x
|
Ill-defined disorder
|
Malaise
|
|
|
|
|
|
|
x
|
Tension
|
Tension
|
|
|
x
|
x
|
|
x
|
|
Urine abnormality
|
Urine abnormality
|
|
|
|
|
|
|
x
|
Urine analysis abnormal
|
Urine abnormality
|
|
|
|
|
|
|
x
|
Erectile dysfunction
|
Erectile dysfunction
|
|
|
x
|
|
x
|
x
|
x
|
Hepatobiliary disease
|
Hepatobiliary disease
|
|
|
x
|
|
x
|
x
|
|
Major depression
|
Psychotic depression
|
|
|
|
|
|
|
x
|
Atrophy
|
Atrophy
|
|
|
x
|
|
|
|
|
Depressed mood
|
Depressed mood
|
|
|
|
|
x
|
x
|
|
Rash maculo-papular
|
Rash maculo-papular
|
|
|
|
|
|
|
x
|
Blindness
|
Blindness
|
|
|
|
|
|
|
x
|
Spermatozoa abnormal
|
Spermatozoa abnormal
|
|
|
|
|
|
|
x
|
Cough
|
Cough increased
|
|
|
|
|
|
|
x
|
Gait disturbance
|
Gait disturbance
|
|
|
|
|
|
|
x
|
Bladder cancer
|
Bladder carcinoma
|
|
|
|
|
|
|
x
|
Nitrogen balance negative
|
Nitrogen balance negative
|
|
|
|
|
|
|
x
|
Embolism
|
Thromboembolic event
|
|
|
x
|
|
x
|
x
|
|
Embolus
|
|
|
|
|
|
|
x
|
Muscular weakness
|
Myasthenia
|
|
|
|
|
|
|
x
|
Retinal vein thrombosis
|
Retinal vein thrombosis
|
|
|
|
|
|
|
x
|
Foetal chromosome abnormality
|
Foetal chromosome abnormality
|
|
|
|
|
|
|
x
|
Breast enlargement
|
Breast enlargement
|
|
|
|
|
|
|
x
|
Hepatic cancer
|
Hepatocellular carcinoma
|
|
|
|
|
|
|
x
|
Hepatocellular carcinoma
|
Hepatocellular carcinoma
|
|
|
|
|
|
|
x
|
Anovulatory cycle
|
Ovulation inhibited
|
|
|
|
|
|
x
|
|
Visual impairment
|
Abnormal vision
|
|
|
|
|
|
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 40 |
Source: | Medsafe |
---|
Side effects: | 27 |
Source: | medicines.org.au |
---|
Side effects: | 48 |
Source: | medicines.org.au |
---|
Side effects: | 52 |
Source: | medicines.org.au |
---|
Side effects: | 116 |
Source: | Health Canada |
---|
Color scheme:
standard – alternative
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|
100%
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75%
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50%
|
|
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10%
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|
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frequent (1% to 100%)
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|
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infrequent (0.1% to 1%)
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|
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rare (<0.1%)
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|
|
postmarketing
|
|
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0%
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|
|
no frequency information
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|
|
not found on label
|