Search results :

Busulfan

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01AB01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12
Nausea Nausea 98% x x x x x x x x x x x x
Stomatitis Stomatitis 85% - 97% x x x x x x x x x x
Mucosal inflammation Mucosal inflammation 97% x x x x x x x x x x x
Vomiting Vomiting 72% - 95% x x x x x x x x x x x x
Decreased appetite Anorexia 85% x x x x x x x x x x x x
Diarrhoea Diarrhoea 58% - 84% x x x x x x x x x x x
Insomnia Insomnia 80% - 84% x x x x x x x x x
Body temperature increased Body temperature increased 80% - 83% x x x x x x x x x x
Fever chills x
Hypomagnesaemia Hypomagnesaemia 77% x x x x x x x x x x
Anxiety Anxiety 65% - 75% x x x x x x x x
Abdominal pain Abdominal pain 72% x x x x x x x x x x
Gastrointestinal pain Abdominal pain 72% x x x x x x x x x x
Headache Headache 69% x x x x x x x x x
Hyperglycaemia Hyperglycaemia 66% x x x x x x x x x x
Hypokalaemia Hypokalaemia 64% x x x x x x x x x x
Dermatitis Rash 50% - 67% x x x x x x x x x x x
Rash Rash 50% - 67% x x x x x x x x x x x
Asthenia Asthenia 51% x x x x x x x x x x x
Fatigue x x
Hyperbilirubinaemia Hyperbilirubinaemia 49% x x x x x x x x x x
Hypocalcaemia Hypocalcaemia 49% x x x x x x x x x
Chills Chills 46% x x x x x x x x x
Dyspepsia Dyspepsia 44% x x x x x x x x x
Pain Pain 44% x x x x x x x x x x
Rhinitis Rhinitis 44% x x x x x x x x x
Tachycardia Tachycardia 44% x x x x x x x x x x
Constipation Constipation 38% x x x x x x x x x x
Oedema Oedema 28% - 79% x x x x x x x x x
Hypertension Hypertension 36% x x x x x x x x x x
Lung disorder Lung disorder 34% x x x x x x x x
Breath sounds abnormal Breath sounds abnormal 34% x x
Thrombosis Thrombosis 27% - 33% x x x x x x x x x x
Infection Infection 31% x x x x x x x x x x x x
Dizziness Dizziness 26% - 30% x x x x x x x x x x
Cough Cough 28% x x x x x x x x x
Dry cough x
Pruritus Pruritus 28% - 29% x x x x x x x x x
Chest pain Chest pain 26% x x x x x x x x x
Hypersensitivity Hypersensitivity 26% x x x x x x x x x x
Dry mouth Dry mouth 26% x x x x x x x x
Dyspnoea Dyspnoea 25% x x x x x x x x x x
Epistaxis Epistaxis 25% x x x x x x x x x
Inflammation Inflammation 25% x x x x x x
Anorectal disorder Rectal disorder 25% x x x x x x x x
Vasodilation procedure Vasodilation 25% x x x x x x x x
Injection site inflammation Injection site inflammation 25% x x x x x x x x x
Back pain Back pain 23% x x x x x x x x x x
Depression Depression 23% x x x x x x x x
Anxiety depression x
Abdominal distension Enlargement abdomen 23% x x x x x x x
Blood creatinine increased Creatinine increased 21% x x x x x x x x
Hiccups Hiccups 17% - 18% x x x x x x x x x
Pharyngitis Pharyngitis 18% - 27% x x x x x x x x x
Asthma Asthma 7% - 8% x x x x x x x x x
Weight increased Weight increased 8% x x x x x x x x x
Skin hyperpigmentation Skin hyperpigmentation 5-10% x x x
Arrhythmia Arrhythmia 3% - 5% x x x x x x x x x
Cardiomegaly Cardiomegaly 5% x x x x x x x x x
Haemoptysis Haemoptysis 3% x x x x x x x
Pleural effusion Pleural effusion 3% x x x x x x x x x
Sinusitis Sinusitis 3% x x x x x x x
Atelectasis Atelectasis 2% - 3% x x x x x x x x x
Pneumothorax Atelectasis 2% - 3% x x x x x x x x x
Atrial fibrillation Atrial fibrillation 2% x x x x x x x x
Cardiac tamponade Cardiac tamponade 2% x x x x
Confusional state Confusional state 2% x x x x x x x x x
Feeling abnormal Confusional state 2% x x x x x x x x x
Delirium Delirium 1% - 2% x x x x x x x x x
Pericardial effusion Pericardial effusion 2% x x x x x x x x x
Encephalopathy Encephalopathy 1% - 2% x x x x x x x x x
Agitation Agitation 1% - 2% x x x x x x x x x
Atrioventricular block complete Atrioventricular block complete 2% x x x x
Ventricular extrasystoles Ventricular extrasystoles 1% - 2% x x x x x x x x x
Hallucination Hallucination 1% x x x x x x x x x
Nervousness Nervousness 1% x x
Tension Nervousness 1% x x
Bradycardia Bradycardia 1% x x
Graft versus host disease Graft versus host disease postmarketing x x x x x x x x x
Chronic myeloid leukaemia Chronic phase chronic myeloid leukemia postmarketing x x x x x x x
Fungal infection Fungal infection postmarketing x
Pulmonary fibrosis Pulmonary fibrosis postmarketing x x x x
Convulsion Convulsion postmarketing x x x x x x x x x x x x
Tumour lysis syndrome Tumour lysis syndrome postmarketing x
Cystitis haemorrhagic Cystitis haemorrhagic postmarketing x x x x x x x x x
Interstitial lung disease Interstitial pneumonia postmarketing x x x x x x x
Lung fibrosis interstitial x x x x x x x x x x
Sepsis Sepsis postmarketing x x
Haematological malignancy Haematological malignancy postmarketing x x x x x x x
Febrile neutropenia Febrile neutropenia postmarketing x x
Chronic graft versus host disease Chronic graft versus host disease postmarketing x x x x x x x x x
Cytomegalovirus viraemia Cytomegalovirus viraemia postmarketing x
Thrombotic microangiopathy Thrombotic microangiopathy postmarketing x
Addison's disease Addison's disease x
Adrenal insufficiency Adrenal insufficiency x x
Agranulocytosis Agranulocytosis x x x x x x x x
Alopecia Alopecia x x x x x x x x x x x x
Amenorrhoea Amenorrhoea x x
Anaemia Anaemia x x x x x x x x x x
Aplastic anaemia Aplastic anaemia x x x
Anhidrosis Anhidrosis x x
Arthralgia Arthralgia x x x x x x x x x x
Musculoskeletal discomfort Arthralgia x x x x x x x x x x
Myalgia x x x x x x x x x x
Ascites Ascites x
Mental disorder Mental disorder x
Neoplasm malignant Neoplasm malignant x x x x x x x x
Coma Coma x x x x x x x x
Connective tissue disorder Connective tissue disorder x
Cystitis Cystitis x
Bladder pain Cystitis x
Cystitis noninfective Cystitis x
Pancytopenia Cytopenia x
Pancytopenia x x x x
Bone marrow depression x
Myelosuppression x x x x x x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative x x x x x x x
Dysuria Dysuria x x x x x x x x x x
Ear disorder Ear disorder x x x x x x x
Endocrine disorder Endocrine disorder x
Erythema multiforme Erythema multiforme x
Erythema nodosum Erythema nodosum x x x x x x x x x
Varices oesophageal Varices oesophageal x x x
Oesophagitis Oesophagitis x x x x x x x x x
Extravasation Extravasation x
Eye disorder Eye disorder x
Fatigue Fatigue x x
Fibrosis Fibrosis x x x x x x
Flushing Flushing x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x
Glossitis Glossitis x
Gynaecomastia Gynaecomastia x x x
Cardiac disorder Cardiac disorder x
Haematemesis Haematemesis x x x x x x x x x
Haematuria Haematuria x x x x x x x x x x
Haemorrhage Haemorrhage x x x x x x x x x x
Haemoglobin Haemorrhage x x x x x x x x x x
Hepatomegaly Hepatomegaly x x x x x x x x x
Hyperventilation Hyperventilation x x x x x x x x x
Hypogonadism Hypogonadism x
Hyponatraemia Hyponatraemia x x x x x x x x x
Hypotension Hypotension x x x x x x x x x
Immune system disorder Immune system disorder x
Infertility Infertility x x
Jaundice Jaundice x x x x x x x x x x x
Jaundice cholestatic Jaundice cholestatic x x
Left ventricular failure Left ventricular failure x x x x x x x
Pulmonary oedema Left ventricular failure x x x x x x x
Lethargy Lethargy x x x x x x x
Leukopenia Leukopenia x x x x
Lymphoma Lymphoma x
Non-Hodgkin's lymphoma Lymphoma x
Mediastinal disorder Mediastinal disorder x
Menopause Menopause x
Multi-organ failure Multi-organ failure x x x x x x x
Myasthenia gravis Myasthenia gravis x x
Necrosis Necrosis x
Neoplasm Neoplasm x
Nervous system disorder Nervous system disorder x
Neutropenia Neutropenia x
Oliguria Oliguria x x x x x x x x x
Opportunistic infection Opportunistic infection x
Pancreatitis Pancreatitis x x x x x x x
Pericarditis Pericarditis x x
Pneumonia Pneumonia x x x x x x x x x x
Delayed puberty Delayed puberty x
Pulmonary valve incompetence Pulmonary valve incompetence x
Rales Rales x
Acute respiratory distress syndrome Acute respiratory distress syndrome x
Serum sickness Serum sickness x
Thrombocytopenia Thrombocytopenia x x x x x x x x x x x
Erythema Erythema x x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x x
Angiopathy Angiopathy x
Weight decreased Weight decreased x x
Arrhythmia supraventricular Atrial arrhythmia x
Acute leukaemia Acute leukaemia x
Hypophosphataemia Hypophosphataemia x x x x x x x x x x
Cataract Cataract x x x x
Hepatitis cholestatic Hepatitis cholestatic x
Blood urea increased Blood urea increased x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Hepatic necrosis Hepatic necrosis x
Injection site pain Injection site pain x x x x x x x x
Prothrombin level increased Prothrombin level increased x x x x x x x
Rash pustular Vesiculobullous rash x x x x x x x
Dermatitis bullous Vesiculobullous rash x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Skin discolouration Skin discolouration x x x x x x x
Pigmentation disorder x
Malnutrition Malnutrition x
Porphyria non-acute Porphyria cutanea tarda x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Rash vesicular Rash vesicular x x x x x x x x
Cheilosis Cheilosis x x
Melanoderma Melanoderma x x
Myalgia Myalgia x x x x x x x x x x
Cardiac fibrillation Cardiac fibrillation x
Neurological symptom Neurological symptom x x x x x x x
Peripheral artery thrombosis Femoral artery thrombosis x x
Menopausal symptoms Menopausal symptoms x
Hot flush x x x x x x x
Skin exfoliation Skin exfoliation x
Hypoxia Hypoxia x
Erectile dysfunction Erectile dysfunction x
Aplasia Aplasia x
Pulmonary ossification Pulmonary ossification x
Hepatobiliary disease Hepatobiliary disease x
Blood bilirubin increased Blood bilirubin increased x
Dystrophic calcification Dystrophic calcification x
Atrophy Atrophy x x
Dysplasia Dysplasia x
Capillary leak syndrome Capillary leak syndrome x x
Organ failure Organ failure x
Rash maculo-papular Rash maculo-papular x x x x x x x x
Transaminases increased Transaminases increased x
Anorectal discomfort Discomfort rectal x x x x x x x x
Anal discomfort x
Fluid overload Fluid overload x x x x x x x x
Pigmentation disorder Pigmentation disorder x
Restrictive cardiomyopathy Endocardial fibrosis x x x
Endocardial fibrosis Endocardial fibrosis x x x
Hot flush Hot flush x x x x x x x
Drug interaction Drug interaction x x
Blood uric acid increased Hyperuricaemia x x x
Hyperuricaemia Hyperuricaemia x x x
Ejection fraction decreased Ejection fraction decreased x
Infestation Infestation NOS x
Acute graft versus host disease Acute graft versus host disease x x
Pulmonary toxicity Pulmonary toxicity x
Venoocclusive disease Venoocclusive disease x x x x x x x x
Hyperuricosuria Hyperuricosuria x x
Corneal thinning Corneal thinning x x x
Respiratory failure Respiratory failure x x x x x x x x x
Ileus Ileus x x x x x x x x x
Death Death x
Renal failure Renal impairment x x
Renal impairment Renal impairment x x
Somnolence Somnolence x x x x x x x
Cerebral haemorrhage Cerebral haemorrhage x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

busulfan / Myleran

Side effects:43
Source:FDA

BUSULFAN / MYLERAN

Side effects:49
Source:Health Canada

Busulfan

Side effects:63
Source:BC Cancer

BUSULFAN / BUSULFEX

Side effects:107
Source:Health Canada

Busulfan

Side effects:117
Source:FDA Structured Product Label

BUSULFAN / BUSULFEX

Side effects:116
Source:FDA

busulfan / BUSULFEX

Side effects:116
Source:FDA

busulfan / BUSULFEX

Side effects:117
Source:FDA

BUSULFAN / BUSULFEX

Side effects:118
Source:FDA

BUSULFAN / BUSULFEX

Side effects:121
Source:FDA

Busulfan

Side effects:122
Source:FDA Structured Product Label

busulfan / busulfan

Side effects:126
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label