Atazanavir
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
Cough
|
Cough
|
21%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cough increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Amylase increased
|
Amylase increased
|
19%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Body temperature increased
|
Body temperature increased
|
postmarketing — 18% - 19%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis
|
Rash
|
postmarketing — 9% - 14%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Rash
|
Rash
|
postmarketing — 9% - 14%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eruption
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
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|
Ocular icterus
|
Scleral icterus
|
postmarketing, 7% - 15%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Ocular icterus
|
common
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Neutropenia
|
Neutropenia
|
9% - 12%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Diarrhoea
|
Diarrhoea
|
postmarketing — 1% - 11%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Vomiting
|
Vomiting
|
common, 3% - 12%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Headache
|
Headache
|
common, 1% - 11%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Jaundice
|
Jaundice
|
postmarketing — 7% - 13%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Oedema peripheral
|
Oedema peripheral
|
7%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
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Nasal congestion
|
Nasal congestion
|
6%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
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|
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Pain in extremity
|
Pain in extremity
|
6%
|
|
|
|
|
|
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|
|
|
|
|
x
|
x
|
x
|
x
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|
|
x
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Wheezing
|
Wheezing
|
6%
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|
|
|
|
x
|
x
|
x
|
x
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|
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|
Nasopharyngitis
|
Rhinorrhoea
|
6%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Rhinorrhoea
|
Rhinorrhoea
|
6%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Oropharyngeal pain
|
Oropharyngeal pain
|
6%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Abdominal pain
|
Abdominal pain
|
common, 4% - 11%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal pain
|
Abdominal pain
|
common, 4% - 11%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
Fatigue
|
common
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Asthenia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Fatigue
|
Fatigue
|
common
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Lipodystrophy acquired
|
Lipodystrophy
|
common
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypoglycaemia
|
Hypoglycaemia
|
4%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Lipase increased
|
Lipase increased
|
3% - 5%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
|
Nausea
|
Nausea
|
postmarketing — 2% - 24%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Haemoglobin decreased
|
Haemoglobin decreased
|
3%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Insomnia
|
Insomnia
|
uncommon, 1% - 5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
Dizziness
|
uncommon, 1% - 8%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Depression
|
Depression
|
postmarketing, 1% - 5%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Abdominal distension
|
Abdominal distension
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Enlargement abdomen
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Amnesia
|
Amnesia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Decreased appetite
|
Anorexia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Anxiety
|
Anxiety
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Chest pain
|
Chest pain
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Retrosternal pain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Drug eruption
|
Drug eruption
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Dysgeusia
|
Dysgeusia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dyspnoea
|
Dyspnoea
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eosinophilia
|
Eosinophilia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Flatulence
|
Flatulence
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Gastritis
|
Gastritis
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Gynaecomastia
|
Gynaecomastia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Haematuria
|
Haematuria
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hepatitis
|
Hepatitis
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypersensitivity
|
Hypersensitivity
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypertension
|
Hypertension
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Muscle atrophy
|
Muscle atrophy
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Neuropathy peripheral
|
Neuropathy peripheral
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Proteinuria
|
Proteinuria
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Protein urine present
|
Proteinuria
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Aphthous stomatitis
|
Aphthous stomatitis
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Shock
|
Syncope
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Syncope
|
Syncope
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Loss of consciousness
|
Syncope
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Pollakiuria
|
Pollakiuria
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Urticaria
|
Urticaria
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Weight increased
|
Weight increased
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Weight decreased
|
Weight decreased
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dry mouth
|
Dry mouth
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Malaise
|
Malaise
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Discomfort
|
Malaise
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Feeling abnormal
|
Malaise
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Confusional state
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Ill-defined disorder
|
Malaise
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Increased appetite
|
Increased appetite
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Disorientation
|
Disorientation
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Sleep disorder
|
Sleep disorder
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Somnolence
|
Somnolence
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Alopecia
|
Alopecia
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Angioedema
|
Angioedema
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
x
|
Arthralgia
|
Arthralgia
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal discomfort
|
Arthralgia
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
postmarketing, uncommon
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cholecystitis
|
Cholecystitis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cholelithiasis
|
Cholelithiasis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cholestasis
|
Cholestasis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Diabetes mellitus
|
Diabetes mellitus
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eczema
|
Eczema
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Oedema
|
Oedema
|
postmarketing, rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Fasting
|
Fasting
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
|
|
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hepatosplenomegaly
|
Hepatosplenomegaly
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hyperglycaemia
|
Hyperglycaemia
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bundle branch block left
|
Bundle branch block left
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Myopathy
|
Myopathy
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Tubulointerstitial nephritis
|
Nephritis interstitial
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
|
|
|
Palpitations
|
Palpitations
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Pancreatitis
|
Pancreatitis
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pruritus
|
Pruritus
|
postmarketing, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Torsade de pointes
|
Torsade de pointes
|
postmarketing, uncommon
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Urethral disorder
|
Urinary tract disorder
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Urinary tract disorder
|
Urinary tract disorder
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Angiopathy
|
Angiopathy
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Atrioventricular block complete
|
Atrioventricular block complete
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Rash pustular
|
Vesiculobullous rash
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dermatitis bullous
|
Vesiculobullous rash
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Malnutrition
|
Malnutrition
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
Myalgia
|
postmarketing, uncommon
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyslipidaemia
|
Dyslipidaemia
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Atrioventricular block second degree
|
Atrioventricular block second degree
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hepatobiliary disease
|
Hepatobiliary disease
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nephrolithiasis
|
Nephrolithiasis
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Calculus of kidney
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Rash maculo-papular
|
Rash maculo-papular
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Renal pain
|
Renal pain
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Gait disturbance
|
Gait disturbance
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Electrocardiogram QT prolonged
|
Electrocardiogram QT corrected interval prolonged
|
postmarketing
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Lactic acidosis
|
Lactic acidosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Amenorrhoea
|
Amenorrhoea
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Atrioventricular block
|
Atrioventricular block
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Block heart
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Autoimmune disorder
|
Autoimmune disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Back pain
|
Back pain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mental disorder
|
Mental disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Breast disorder
|
Breast disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Cellulitis
|
Cellulitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Colitis
|
Colitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Infection
|
Infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Confusional state
|
Confusional state
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Connective tissue disorder
|
Connective tissue disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Constipation
|
Constipation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Libido decreased
|
Libido decreased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Disturbance in sexual arousal
|
Libido decreased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dehydration
|
Dehydration
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dermatophytosis
|
Dermatophytosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dyspepsia
|
Dyspepsia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Ecchymosis
|
Ecchymosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Erythema multiforme
|
Erythema multiforme
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Stevens-Johnson syndrome
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Oesophagitis
|
Oesophagitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Eye disorder
|
Eye disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Gastroenteritis
|
Gastroenteritis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Gout
|
Gout
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Basedow's disease
|
Basedow's disease
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hallucination
|
Hallucination
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Cardiac arrest
|
Cardiac arrest
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hepatitis C
|
Hepatitis C
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Hepatomegaly
|
Hepatomegaly
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hiccups
|
Hiccups
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hostility
|
Hostility
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperbilirubinaemia
|
Hyperbilirubinaemia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hypercholesterolaemia
|
Hypercholesterolaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hypertriglyceridaemia
|
Hypertriglyceridaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Blood triglycerides increased
|
Hypertriglyceridaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Breast enlargement
|
Hypertrophy of breast
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hypoaesthesia
|
Hypoaesthesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Immune system disorder
|
Immune system disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Inflammation
|
Inflammation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Insulin resistance
|
Insulin resistance
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Mediastinal disorder
|
Mediastinal disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Menstrual disorder
|
Menstrual disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Myocarditis
|
Myocarditis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Nail disorder
|
Nail disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Nervous system disorder
|
Nervous system disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Nervousness
|
Nervousness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Tension
|
Nervousness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Obesity
|
Obesity
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Oliguria
|
Oliguria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Opportunistic infection
|
Opportunistic infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Ear infection
|
Otitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Pain
|
Pain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Pallor
|
Pallor
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Pelvic pain
|
Pelvic pain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Peptic ulcer
|
Peptic ulcer
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Polyuria
|
Polyuria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Urine output increased
|
Polyuria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Psychotic disorder
|
Psychotic disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Purpura
|
Purpura
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Vascular purpura
|
Purpura
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Renal failure
|
Renal failure
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Seborrhoeic dermatitis
|
Seborrhoeic dermatitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Convulsion
|
Convulsion
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Staphylococcal scalded skin syndrome
|
Staphylococcal scalded skin syndrome
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Stevens-Johnson syndrome
|
Stevens-Johnson syndrome
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Suicide attempt
|
Suicide attempt
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperhidrosis
|
Sweating
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Tinnitus
|
Tinnitus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Toothache
|
Toothache
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Urinary tract infection
|
Urinary tract infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hepatitis viral
|
Hepatitis viral
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Burning sensation
|
Burning sensation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Agitation
|
Agitation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperkinesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mood swings
|
Mood swings
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Affect lability
|
Mood swings
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Stomatitis
|
Mouth ulceration
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mouth ulceration
|
Mouth ulceration
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Crystalluria
|
Crystalluria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Generalised oedema
|
Generalised oedema
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Fluid retention
|
Generalised oedema
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Infertility male
|
Fertility male decreased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hepatocellular injury
|
Hepatocellular injury
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Liver injury
|
Hepatocellular injury
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hepatic steatosis
|
Liver fatty deposition
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Bone pain
|
Bone pain
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperreflexia
|
Hyperreflexia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Aspartate aminotransferase increased
|
Aspartate aminotransferase increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Alanine aminotransferase increased
|
Alanine aminotransferase increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
|
Dry skin
|
Dry skin
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Oesophageal ulcer
|
Oesophageal ulcer
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Temperature intolerance
|
Heat intolerance
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Muscle twitching
|
Muscle twitching
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Neurological symptom
|
Neurological symptom
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Urine abnormality
|
Urine abnormality
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Urine analysis abnormal
|
Urine abnormality
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Erectile dysfunction
|
Erectile dysfunction
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Blood bilirubin increased
|
Blood bilirubin increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Bilirubin total increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Atrophy
|
Atrophy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dysplasia
|
Dysplasia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Photosensitivity reaction
|
Photosensitivity
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperkinesia
|
Hyperkinesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Lipohypertrophy
|
Buffalo hump
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Lipohypertrophy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Chronic hepatitis B
|
Chronic hepatitis B
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Drug interaction
|
Drug interaction
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Hyperlactacidaemia
|
Hyperlactacidaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Muscular weakness
|
Myasthenia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Deficiency of bile secretion
|
Acholia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 11 |
Source: | FDA |
---|
Side effects: | 17 |
Source: | FDA |
---|
Side effects: | 17 |
Source: | FDA |
---|
Side effects: | 27 |
Source: | FDA |
---|
Side effects: | 27 |
Source: | FDA |
---|
Side effects: | 28 |
Source: | FDA |
---|
Side effects: | 34 |
Source: | FDA |
---|
Side effects: | 35 |
Source: | FDA |
---|
Side effects: | 38 |
Source: | FDA |
---|
Side effects: | 38 |
Source: | FDA |
---|
Side effects: | 44 |
Source: | FDA Structured Product Label |
---|
Side effects: | 44 |
Source: | FDA Structured Product Label |
---|
Side effects: | 47 |
Source: | FDA Structured Product Label |
---|
Side effects: | 50 |
Source: | FDA Structured Product Label |
---|
Side effects: | 81 |
Source: | Health Canada |
---|
Side effects: | 97 |
Source: | EMA |
---|
Side effects: | 135 |
Source: | FDA |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|