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Dasatinib

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XE06

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Thrombocytopenia Thrombocytopenia postmarketing, 5% - 85% x x x x x x x
Neutropenia Neutropenia 20% - 80% x x x x x x x
Anaemia Anaemia 3% - 75% x x x x x x x
Hypophosphataemia Hypophosphataemia 5% - 28% x x x x x x
Fluid retention Fluid retention very common, 1% - 50% x x x x x x x
Generalised oedema common, 0% - 7% x x x x x x x
Asthenia Fatigue very common, 0% - 26% x x x x x x x
Asthenia common, 1% - 6% x x x x x x x
Fatigue Fatigue very common, 0% - 26% x x x x x x x
Pleural effusion Pleural effusion 0% - 24% x x x x x x
Febrile neutropenia Febrile neutropenia 1% - 20% x x x x x x x
Dermatitis Rash 0% - 21% x x x x x x x
Dermatitis x x x x x x x
Rash Rash 0% - 21% x x x x x x x
Hypocalcaemia Hypocalcaemia 1% - 20% x x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 0% - 14% x x x x x x x
Headache Headache very common, 0% - 33% x x x x x x x
Pneumonia Pneumonia 3% - 11% x x x x x x x
Infection Infection postmarketing, 0% - 15% x x x x x x x
Diarrhoea Diarrhoea 0% - 31% x x x x x x x
Body temperature increased Body temperature increased very common, 0% - 18% x x x x x x x
Flushing Flushing common x x x x x x x
Palpitations Palpitations common x x x x x x x
Muscle spasms Muscle spasms common, 0% - 21% x x x
Tachycardia Tachycardia common x x x x x
Tinnitus Tinnitus common x x x x x x x
Muscular weakness Muscular weakness common x x x x x x x
Musculoskeletal stiffness Musculoskeletal stiffness common x x x x x x x
Hypokalaemia Hypokalaemia 0% - 15% x x x
Dyspnoea Dyspnoea 2% - 24% x x x x x x x
Nausea Nausea 0% - 24% x x x x x x x
Pain Pain common, 1% - 10% x x x x x x x
Musculoskeletal pain Musculoskeletal pain 0% - 22% x x x x x x x
Abdominal pain Abdominal pain 0% - 12% x x x x x x x
Gastrointestinal pain Abdominal pain 0% - 12% x x x x x x x
Chest pain Chest pain common, 0% - 13% x x x x x x x
Localised oedema Localised oedema 0% - 37% x x x x x
Cardiac failure Cardiac failure 3% x x x x x
Oedema Oedema 0% - 36% x x x x x x x
Pitting edema x x
Alanine aminotransferase increased Alanine aminotransferase increased 0% - 11% x x x x x
Myositis Myositis uncommon, 0% - 19% x x x x x x x
Decreased appetite Anorexia 1% - 3% x x x x x x x
Arrhythmia Arrhythmia common, 1% - 11% x x x x x x x
Colitis Colitis 2% x x x x x x x
Haemorrhage Haemorrhage 0% - 26% x x x x x x x
Haemoglobin Haemorrhage 0% - 26% x x x x x x x
Vomiting Vomiting 0% - 16% x x x x x x x
Myalgia Myalgia common, 0% - 13% x x x x x x x
Musculoskeletal discomfort Myalgia common, 0% - 13% x x x x x x x
Arthralgia common, 0% - 12% x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased 0% - 8% x x x x x
Arthralgia Arthralgia common, 0% - 12% x x x x x x x
Ascites Ascites 0% - 2% x x x x x x x
Inflammation Inflammation 1% - 5% x x x x x x x
Pericardial effusion Pericardial effusion common, 0% - 4% x x x x x x x
Neuropathy peripheral Neuropathy peripheral 0% - 13% x x x x x x x
Neuropathy 0% - 13% x x x x x x x
Weight increased Weight increased 1% - 11% x x x x x x x
Weight decreased Weight decreased 0% - 14% x x x x x x x
Blood creatinine increased Creatinine increased 0% - 8% x x x x x
Generalised oedema Generalised oedema common, 0% - 7% x x x x x x x
Blood bilirubin increased Blood bilirubin increased 0% - 8% x x x x x
Amnesia Amnesia uncommon x x x x x x x
Asthma Asthma uncommon x x x x x x x
Mental disorder Mental disorder uncommon x x x x x x x
Breast disorder Breast disorder uncommon x x x x x x x
Bronchospasm Bronchospasm uncommon x x x x x x x
Cholecystitis Cholecystitis uncommon x x x x x x x
Cholestasis Cholestasis uncommon x x x x x x x
Gynaecomastia Gynaecomastia uncommon x x x x x x x
Hepatitis Hepatitis uncommon x x x x x x x
Hypotension Hypotension uncommon x x x x x x x
Rhabdomyolysis Rhabdomyolysis uncommon x x x x x x x
Dizziness Syncope uncommon x x x x x x x
Dizziness 0% - 14% x x x x x x x
Shock Syncope uncommon x x x x x x x
Syncope Syncope uncommon x x x x x x x
Loss of consciousness Syncope uncommon x x x x x x x
Tendonitis Tendonitis uncommon x x x x x x x
Thrombophlebitis Thrombophlebitis uncommon x x x x x
Tremor Tremor uncommon x x x x x x x
Vertigo Vertigo uncommon x x x x x x x
Menstruation irregular Menstruation irregular uncommon x x x x x
Malaise Malaise uncommon x x x x x x x
Discomfort Malaise uncommon x x x x x x x
Feeling abnormal Malaise uncommon x x x x x x x
Confusional state x x x x x x x
Ill-defined disorder Malaise uncommon x x x x x x x
Blood creatine phosphokinase increased Blood creatine phosphokinase increased uncommon x x x x x x x
Temperature intolerance Temperature intolerance uncommon x x x x x x x
Constipation Constipation 0% - 14% x x x x x x x
Cough Cough 0% - 1% x x x x x x x
Hypertension Hypertension postmarketing — 0% - 2% x x x x x x x
Cardiac failure congestive Cardiac failure congestive common, 0% - 4% x x x x x x x
Atrial fibrillation Atrial fibrillation postmarketing x x x x
Atrial flutter Atrial flutter postmarketing x x x
Neoplasm malignant Neoplasm malignant postmarketing x x
Cardiovascular disorder Cardiovascular disorder postmarketing x
Embolism Embolism postmarketing x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing, rare x x x x x x x
Cardiac disorder Cardiac disorder postmarketing x x x
Mediastinal disorder Mediastinal disorder postmarketing x x x x x x x
Nervous system disorder Nervous system disorder rare x x x x x x x
Pulmonary embolism Pulmonary embolism postmarketing x x x x
Aplasia pure red cell Aplasia pure red cell rare x x x x x x x
Acute respiratory distress syndrome Acute respiratory distress syndrome rare x x x x x x x
Thrombosis Thrombosis postmarketing x x x x
Angiopathy Angiopathy postmarketing x x x x x x x
Livedo reticularis Livedo reticularis rare x x x x x x x
Deep vein thrombosis Deep vein thrombosis postmarketing x x x x
Interstitial lung disease Interstitial lung disease postmarketing x x x x
Sepsis Sepsis postmarketing, 1% x x x x x x x
Abdominal distension Abdominal distension 0% - 11% x x x x x x x
Alopecia Alopecia x x x x x x x
Angina pectoris Angina pectoris x x x x x x x
Anxiety Anxiety x x x x x x x
Coagulopathy Coagulopathy x x
Congestive cardiomyopathy Congestive cardiomyopathy x x x
Transient ischaemic attack Transient ischaemic attack x x x x x x x
Confusional state Confusional state x x x x x x x
Conjunctival haemorrhage Conjunctival haemorrhage x
Conjunctivitis Conjunctivitis x x x x x x x
Connective tissue disorder Connective tissue disorder x x x x x x x
Contusion Contusion x x x x x x x
Cyst Cyst x x
Pancytopenia Cytopenia x x
Pancytopenia x x x x x x x
Myelosuppression x x x x x x x
Libido decreased Libido decreased x x x x x x x
Disturbance in sexual arousal Libido decreased x x x x x x x
Dysphagia Dysphagia x x x x x x x
Drug eruption Drug eruption x x x x
Dysgeusia Dysgeusia x x x x x x x
Dyspepsia Dyspepsia x x x x x x x
Ecchymosis Ecchymosis x
Eczema Eczema x x x x x x x
Epistaxis Epistaxis x x
Erythema multiforme Erythema multiforme x x x
Erythema nodosum Erythema nodosum x x x x x
Oesophagitis Oesophagitis x x x x x x x
Eye disorder Eye disorder x x x x x x x
Eye haemorrhage Eye haemorrhage x
Anal fissure Anal fissure x x x x x x x
Gastritis Gastritis x x x x x x x
Gingival bleeding Gingival bleeding x
Cardiomegaly Cardiomegaly x x x x x x x
Haematoma Haematoma x
Subdural haematoma Subdural haematoma x x
Haematuria Haematuria x
Haemoptysis Haemoptysis x
Herpes virus infection Herpes virus infection x x x x x x x
Hyperhidrosis Hyperhidrosis x x x x x x x
Hypersensitivity Hypersensitivity x x x x x x x
Pulmonary hypertension Pulmonary hypertension 0% - 2% x x x x x
Immune system disorder Immune system disorder x x x x x x x
Left ventricular failure Left ventricular failure x x
Pulmonary oedema Left ventricular failure x x
Pulmonary oedema 0% - 4% x x x x x x x
Chronic myeloid leukaemia Chronic myeloid leukaemia x
Myocardial infarction Myocardial infarction x x x x x x x
Acute coronary syndrome Myocardial infarction x x x x x x x
Acute coronary syndrome x x x x x x x
Myocarditis Myocarditis x x x x x x x
Nail disorder Nail disorder x x x x x x x
Neoplasm Neoplasm x x x x x x x
Oligomenorrhoea Oligomenorrhoea x x
Optic neuritis Optic neuritis x x x x
Pancreatitis Pancreatitis x x x x x x x
Panniculitis Panniculitis x x x x x
Pericarditis Pericarditis x x x x x x x
Petechiae Petechiae x x
Polyp Polyp x x
Proteinuria Proteinuria x x x x x x x
Protein urine present Proteinuria x x x x x x x
Prurigo Prurigo x x x x x
Pruritus Pruritus 0% - 11% x x x x x x x
Cor pulmonale Cor pulmonale x x x x
Renal failure Renal failure x x x x x x x
Convulsion Convulsion x x x x x x x
Skin ulcer Skin ulcer x x x x x x x
Stomatitis Stomatitis x x x x x x x
Cerebrovascular accident Cerebrovascular accident x x x x x x x
Subarachnoid haemorrhage Subarachnoid haemorrhage x x
Tumour lysis syndrome Tumour lysis syndrome x x x x x x x
Erythema Erythema x x x x x
Upper respiratory tract infection Upper respiratory tract infection x x x x x
Pollakiuria Pollakiuria x x x x x x x
Urethral disorder Urinary tract disorder x x x x x x x
Urinary tract disorder Urinary tract disorder x x x x x x x
Urticaria Urticaria x x x x x x x
Uterine haemorrhage Uterine haemorrhage x
Ventricular tachycardia Ventricular tachycardia x x x x x x x
Visual impairment Disorder sight x x x x x
Visual disturbance x x x x
Visual impairment x x x
Acute febrile neutrophilic dermatosis Acute febrile neutrophilic dermatosis x x x x x x x
Chills Chills common, 0% - 11% x x x x x x x
Ventricular arrhythmia Ventricular arrhythmia x x x x x
Rash pustular Rash pustular x x x x x
Oedema peripheral Oedema peripheral x x
Periorbital oedema Periorbital oedema x x
Conjunctival oedema Conjunctival oedema x x
Swelling face Swelling face x x
Oedema genital Oedema genital x x
Scrotal oedema Scrotal oedema x x
Tongue disorder Tongue oedema x x
Tongue oedema Tongue oedema x x
Haemorrhage intracranial Haemorrhage intracranial x x
Electrocardiogram QT prolonged Electrocardiogram QT prolonged x x
Electrocardiogram QT corrected interval prolonged x x
Dry skin Dry skin x x x x x x x
Skin irritation Skin irritation x x x
Penile oedema Penile oedema x x
Eyelid oedema Eyelid oedema x x
Miliaria Miliaria rubra x x x
Malnutrition Malnutrition x x x x x x x
Photosensitivity reaction Photosensitivity reaction x x
Photosensitivity x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x x x x
Rash macular Rash macular x x x x x
Rash vesicular Rash vesicular x x x x x
Affect lability Affect lability x x x x x x x
Visual acuity reduced Visual acuity reduced x x x x
Rash erythematous Rash erythematous x x x x
Rash follicular Rash follicular x x x x x
Urticaria vesiculosa Urticaria vesiculosa x x x x x
Gravitational oedema Gravitational oedema x x
Lung infiltration Lung infiltration x x x x x x x
Oedema mouth Oedema mouth x x
Skin exfoliation Skin exfoliation x x x x x
Gastrointestinal ulcer Gastrointestinal ulcer x x x x x x x
Epidural haemorrhage Epidural haemorrhage x x
Genital rash Genital rash x x
Hypoalbuminaemia Hypoalbuminaemia x x x x x x
Left ventricular dysfunction Left ventricular dysfunction x x x x
Ventricular dysfunction Ventricular dysfunction x x x x
Cardiac failure acute Cardiac failure acute x
Oral disorder Oral soft tissue disorder NOS x x x x x x x
Hepatobiliary disease Hepatobiliary disease x x x x x x x
Eye swelling Eye swelling x x
Macular oedema Macular oedema x x
Ear haemorrhage Ear haemorrhage x
Skin swelling Skin swelling x x
Protein-losing gastroenteropathy Protein-losing gastroenteropathy x x x x
Dry eye Dry eye x x x x x x x
Mucosal inflammation Mucosal inflammation x x x x x x x
Vision blurred Vision blurred x x x x
Milia Milia x x x x x
Lipoedema Lipoedema x x
Neutropenic colitis Neutropenic colitis x x x x x
Rash maculo-papular Rash maculo-papular x x x x x
Orbital oedema Orbital oedema x x
Intra-abdominal haematoma Intra-abdominal haematoma x
Rash generalised Rash generalised x x x x x
Diastolic dysfunction Diastolic dysfunction x x x
Systemic lupus erythematosus rash Systemic lupus erythematosus rash x x x
Platelet aggregation abnormal Platelet aggregation abnormal x x
Lip oedema Lip oedema x x
Cerebral haematoma Cerebral haematoma x x
Face oedema Face oedema x x
Auricular swelling Auricular swelling x x
Skin discolouration Pigmentation disorder x x x x x x x
Pigmentation disorder Pigmentation disorder x x x x x x x
Haemorrhagic stroke Haemorrhagic stroke x x
Cerebral haemorrhage Haemorrhagic stroke x x
Cerebral haemorrhage x x
Blood uric acid increased Hyperuricaemia x x x x x x x
Hyperuricaemia Hyperuricaemia x x x x x x x
Ejection fraction decreased Ejection fraction decreased x x x x x
Eye oedema Eye oedema x x
Scleral haemorrhage Scleral haemorrhage x
Generalised erythema Generalised erythema x x x x x
Ventricular failure Ventricular failure x x x
Infestation Infestation NOS x x x x x x x
Blood calcium decreased Calcium low x
Cardiomyopathy Cardiomyopathy x x x x x
Insomnia Insomnia x x x x x x x
VIIth nerve paralysis VIIth nerve paralysis x x x
Erythrosis Erythrosis x x
Troponin increased Troponin increased x x
Enterocolitis infectious Enterocolitis infectious x x x x x x x
Ileus Ileus x x x x x
Rash papular Rash papular x x x x x
Exfoliative rash Exfoliative rash x x x x x
Incision site oedema Incision site oedema x x
Genital swelling Genital swelling x x
Somnolence Somnolence x x x x x x x
Vaginal haemorrhage Vaginal haemorrhage x
Posterior reversible encephalopathy syndrome Posterior reversible encephalopathy syndrome x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

dasatinib

Side effects:177
Source:FDA Structured Product Label

dasatinib anhydrous

Side effects:183
Source:FDA Structured Product Label

DASATINIB / SPRYCEL

Side effects:178
Source:FDA

DASATINIB / SPRYCEL

Side effects:178
Source:FDA

DASATINIB / SPRYCEL

Side effects:185
Source:FDA

dasatinib / dasatinib

Side effects:241
Source:EMA

SPRYCEL (Dasatinib) / General

Side effects:252
Source:medicines.org.au

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label