Ambrisentan

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Anaemia def Anaemia def postmarketing x x
Angioedema def Angioedema def postmarketing x x
Dermatitis def Rash def postmarketing x x
Rash def Rash def postmarketing x x
Cardiac failure def Cardiac failure def postmarketing x
Hepatitis def Hepatitis def postmarketing x
Hypersensitivity def Hypersensitivity def postmarketing x x
Nausea def Nausea def postmarketing x x
Vomiting def Vomiting def postmarketing x
Hepatic failure def Hepatic failure def postmarketing x
Hepatic function abnormal Hepatic function abnormal postmarketing x
Fluid retention Fluid retention postmarketing x x
Abdominal pain def Abdominal pain def 0.758% x x
Gastrointestinal pain def Abdominal pain def 0.758% x x
Angina pectoris def Angina pectoris def x
Cardiac pain x
Decreased appetite Anorexia def x
Arthralgia def Arthralgia def x
Musculoskeletal discomfort Arthralgia def x
Myalgia def x
Mental disorder def Mental disorder def x
Breast disorder def Breast disorder def x
Chest pain def Chest pain def x
Chest discomfort x
Constipation def Constipation def 1.52% x x
Cough def Cough def x
Diarrhoea def Diarrhoea def x
Dizziness def Dizziness def x
Dyspnoea def Dyspnoea def 3.03% x x
Oedema def Oedema def 10.6% x x
Effusion def Effusion def x
Body temperature increased def Body temperature increased def x
Flushing def Flushing def 0.758% x x
Gastritis def Gastritis def x
Gastrointestinal disorder def Gastrointestinal disorder def x
Headache def Headache def 13.6% x x
Cardiac disorder def Cardiac disorder def x
Haemolysis def Haemolysis def x
Haemorrhage def Haemorrhage def x
Haemoglobin def Haemorrhage def x
Pulmonary hypertension def Pulmonary hypertension def x x
Hypokalaemia def Hypokalaemia def x
Immune system disorder def Immune system disorder def x
Infection def Infection def x
Influenza def Influenza def x
Mediastinal disorder def Mediastinal disorder def x
Muscle spasms def Cramp muscle def x
Nasal congestion def Nasal congestion def 1.52% x x
Nasopharyngitis def Nasopharyngitis def 0.758% x x
Nocturia def Nocturia def x
Pain def Pain def 0.758% x x
Palpitations def Palpitations def 2.27% x x
Pharyngitis def Pharyngitis def x
Pleural disorder def Pleural disorder def x
Pleural effusion def Pleural effusion def x
Pneumonia def Pneumonia def x
Pruritus def Pruritus def x
Rales Rales x
Respiratory tract infection def Respiratory tract infection def x
Rhinitis def Rhinitis def x
Sinusitis def Sinusitis def 0% x x
Skin ulcer def Skin ulcer def x
Tachycardia def Tachycardia def x
Ulcer def Ulcer def x
Upper respiratory tract infection def Upper respiratory tract infection def x
Urethral disorder def Urinary tract disorder def x
Urinary tract disorder def Urinary tract disorder def x
Wheezing def Wheezing def x
Oedema peripheral def Oedema peripheral def 10.6% x x
Haemoglobin decreased def Haemoglobin decreased def x
Myalgia def Myalgia def x
Discomfort def Discomfort def x
Chest discomfort Chest discomfort x
Lymphadenopathy def Lymphadenopathy def x
Aortic dissection def Dissecting aortic aneurysm, thoracic x
Haematocrit decreased Haematocrit decreased x
Ventricular failure Ventricular failure x
Infestation Infestation NOS x
Sleep disorder def Sleep disorder def x
Insomnia def Insomnia def x
Right ventricular failure def Right ventricular failure def x
Vaginal haemorrhage def Vaginal haemorrhage def x
Indication Labels
Connective tissue disorder def x x
Hypertension def x x
Primary pulmonary hypertension x
Pulmonary arterial hypertension x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: C02KX02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. ambrisentan : 24 side effects (FDA XML label)
  2. AMBRISENTAN / VOLIBRIS : 70 side effects (Health Canada)