Imiquimod

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 15)
1 2 3 4 5 6 7 8 9 10
Erythema def postmarketing, 0% - 100% 0% - 97.2% x x x x x x x x x x
Skin exfoliation 0% - 93% 0% - 90.5% x x x x x x x x x
Induration def 0% - 84% 0% - 53% x x x x x x x x x
Scab 0% - 83% 0% - 41.8% x x x x x x x x x x
Oedema def postmarketing, 0% - 78% 0% - 36% x x x x x x x x x x
Ulcer def 0% - 48% 0% - 9.09% x x x x x x x x x x
Application site reaction 28% - 33% 2.79% - 14.5% x x x x x x x x
Pruritus def 2.75% - 32.5% 0.559% - 20.4% x x x x x x x x x x
Tearfulness 0% - 22% 0% - 1.36% x x x x x x x
Infection def postmarketing, 1% - 15.3% 0% - 12.2% x x x x x x x x x x
Upper respiratory tract infection def 3% - 15.3% 1% - 12.2% x x x x x x x
Fungal infection def 1% - 11.1% 0.633% - 2.91% x x x x x x x x
Headache def 1.5% - 8% 0.495% - 3.17% x x x x x x x x x x
Pain def postmarketing, 1% - 8% 0% - 1.94% x x x x x x x x x x
Sinusitis def 2% - 7.44% 0.559% - 6.33% x x x x x x x x
Fatigue def 1% - 4.38% 0.905% - 1.12% x x x x x x x x x x
Back pain def 1% - 4% 0.559% - 1% x x x x x x x x
Squamous cell carcinoma def 3.72% - 4% 2% - 2.26% x x x x x x x x
Influenza def 0% - 3.75% 0% - 1.94% x x x x x x x x x x
Nausea def 0.625% - 3.75% 0% - 1.26% x x x x x
Sickness 0.625% - 3.75% x
Influenza like illness 0.625% - 3.75% x
Haemorrhage def 2% - 3.26% 0% - 1% x x x x x x x x x x
Body temperature increased def 0% - 3.12% 0% x x x x x x x x x x
Diarrhoea def 1.25% - 3% 0.905% - 1% x x x x x x x x x x
Rhinitis def 2.7% - 3% 0.559% - 1% x x x x
Tenderness def 0% - 3% 0% - 1.36% x x x x x x x x x
Lymphadenopathy def 1.88% - 3% 0.559% - 1% x x x x
Stinging 2.79% - 3% 0.905% - 1% x x x x x x x x x
Anorexia def 0% - 2.5% x
Arthralgia def postmarketing, 1.25% - 2.5% x x x x x x x
Dizziness def 0.625% - 2.5% 0.452% - 1% x x x x x x x x
Herpes NOS def postmarketing, 0% - 2.5% 0.629% x x x x x x x
Herpes simplex def postmarketing, 0% - 2.5% 0.629% x x x x x x x
Oral herpes 0% - 2.5% x
Cough def 1.62% - 2% 0.559% - 1% x x x x
Dyspepsia def 1.62% - 2% 1% - 1.12% x x x x
Eczema def 1.86% - 2% 1% - 1.36% x x x x x x x
Papule def 1.62% - 2% 0% x x x
Cheilitis def 0% - 1.88% x
Vaginal inflammation def 1.5% 0.99% x
Vaginitis bacterial def 1.5% 0.99% x
Alopecia def 1% - 1.4% 0% x x x x x x x
Atrial fibrillation def postmarketing, 1% - 1.4% 0.905% - 1% x x x x x x x x x
Urinary tract infection def 1% - 1.4% 0.452% - 1% x x x x x x x
Vomiting def 1% - 1.4% 0.452% - 1% x x x x x x x x
Cardiac fibrillation postmarketing, 1% - 1.4% 0.905% - 1% x x x x x x x x x
Rigors 1% - 1.4% 0% x x x x x x x
Myalgia def 0% - 1.28% 0% - 0.633% x x x x x x x x x x
Anxiety def 1% - 1.08% 0.559% - 1% x x x
Chest pain def postmarketing, 1% - 1.08% 0% x x x x x x x x x
Pharyngitis def 1% - 1.08% 0.559% - 1% x x x x
Abdominal pain def postmarketing x x x x x x
Angioedema def postmarketing x x x x x x x
Arrhythmia def postmarketing x x x x x x x
Convulsion def postmarketing x x x x x x x
Febrile convulsion def postmarketing x x x x x x x
Dermatitis def postmarketing x x x x x x x x x
Dermatitis exfoliative def postmarketing x x x x x x x
Dyspnoea def postmarketing x x x x x x x
Dysuria def postmarketing x x x x x
Erythema multiforme def postmarketing x x x x x x
Cardiac failure def postmarketing x x x x x x x
Hypertrophy def postmarketing x x x x x
Infarction def postmarketing x x x x x x x
Ischaemia def postmarketing x x x x x x x
Lymphoma def postmarketing x x x x x x x
Multiple sclerosis def postmarketing x x x x x x x
Myocardial infarction def postmarketing x x x x x x x
Palpitations def postmarketing x x x x x x x
Paresis def postmarketing x x x x x x x
Proteinuria def postmarketing x x x x x x x
Pulmonary oedema def postmarketing x x x x x x x
Purpura def postmarketing x x x x x x x
Cerebrovascular accident def postmarketing x x x x x x x
Suicide def postmarketing x x x x x x x
Syncope def postmarketing x x x x x x x
Tachycardia def postmarketing x x x x x x x
Supraventricular tachycardia def postmarketing x
Thyroiditis def postmarketing x x x x x x x
Urinary tract disorder def postmarketing x x x x x x x x
Idiopathic thrombocytopenic purpura def postmarketing x x x x x x x
Urinary retention def postmarketing x x x x x
Agitation def postmarketing x x x x x x x
Hepatic function abnormal postmarketing x x x x x x x
Hypertrophic scar def postmarketing x x x x
Skin hyperpigmentation def postmarketing x x x x x x x
Leukoderma def postmarketing x x x x x x x x x x
Osteoarthropathy def postmarketing x x x x x x x x x x
Capillary leak syndrome def postmarketing x x x x x x x
Infestation NOS postmarketing x x x x x
Thrombocytopenic purpura def postmarketing x x x x x x x
Cardiomyopathy def postmarketing x x x x x x x
Insomnia def postmarketing x x x x x x x
Scar def postmarketing x x x x x x x
Tingling sensation def postmarketing x x x x x x
Arthritis def x x
Mental disorder def x
Bronchitis def x x
Cardiovascular disorder def x x
Cellulitis def x
Conjunctivitis def x x
Cyst def x x
Rash def x x x x x x x x x x
Congenital eye disorder def x x
Eye infection def x x
Gastrooesophageal reflux disease def x x
Gout def x
Hernia def x x
Herpes zoster def x
Hypercholesterolaemia def x x
Hypersensitivity def x
Hypertension def x x
Unspecified disorder of intestine def x
Lethargy def x
Nervous system disorder def x x x x x x x x x
Pancytopenia def x
Neuropathy peripheral def x x x x x x x x x
Respiratory disorder def x x
Skin disorder def x x
Swelling def x
Tinea infection def x x x x x x x x x
Tooth disorder def x
Chills def x
Scrotal oedema x
Bone pain def x x
Photosensitivity reaction def x x
Allergy aggravated x
Scrotal pain def x
Scrotal erythema x
Pulmonary congestion x x
Scrotal ulcer x
Photosensitivity def x x
Influenza-like symptoms def
Local reaction x x x x x x x x
Hyperkeratosis def x x
Hepatic lymphoma
Sensitisation def x x x x x x x x
Tinea cruris x x x x x x x x x
Phototoxicity def x x
Indication Labels
Actinic keratosis def x x x x x x x x x
Anogenital warts def x x x x x x x x x x
Basal cell carcinoma def x x x x x
Basal cell naevus syndrome def x x x x x x
Carcinoma def x x x x x
Common wart def x x x x x x x x x x
Condyloma x x x x x x x x x x
Keratosis def x x x x x x x x x
Molluscum contagiosum def x x x x x x x
Neoplasm def x x x x
Nevus def x x x x x x
Nevus cell nevus x x x x x x
Papilloma def x
Perianal warts x x x x x x x x x x
Superficial basal cell carcinoma x x x x x
Viral infection def x
Xeroderma def x x x x x x x
Xeroderma pigmentosum def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: D06BB10

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. imiquimod / Aldara : 25 side effects (FDA CDER)
  2. imiquimod / Aldara : 72 side effects (FDA MedWatch)
  3. IMIQUIMOD : 75 side effects (FDA XML label)
  4. imiquimod : 77 side effects (FDA XML label)
  5. IMIQUIMOD / ALDARA : 83 side effects (Drugs@FDA)
  6. Imiquimod : 85 side effects (FDA XML label)
  7. IMIQUIMOD : 87 side effects (FDA XML label)
  8. Imiquimod : 87 side effects (FDA XML label)
  9. imiquimod : 90 side effects (FDA XML label)
  10. IMIQUIMOD : 92 side effects (FDA XML label)