Options: Show MedDRA Preferred Terms, display all 96 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Neuropathy peripheral | 46.1% | 24.2% | x | x | x | x | x | |||||||||||||||
Connective tissue disorder | 33% - 34% | 35% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Insomnia | 0.3% - 32% | 8% - 37% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Infestation NOS | 2% - 25% | 1% - 26% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Mental disorder | postmarketing, 0% - 40% | 0% - 41% | x | |||||||||||||||||||
Immune system disorder | postmarketing, 21% - 22% | 23% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Extrapyramidal symptoms | 1.4% - 34% | 0% - 16% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Enuresis | 1.1% - 16% | 5.2% - 10% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Urinary tract disorder | postmarketing, 16% - 43% | 10% - 44% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Nervous system disorder | postmarketing, 14% - 37% | 8% - 38% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Extrapyramidal disorder | 7% - 19.6% | 6.11% - 7% | x | x | x | x | x | x | ||||||||||||||
Abdominal pain upper | 0.7% - 16% | 0% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Drooling | 0% - 16% | 0% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Headache | 3% - 22.4% | 7.33% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Rhinorrhoea | 1.5% - 16% | 0.8% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Ear and labyrinth disorders | 9% - 10% | 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Constipation | 1% - 21% | 1% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Respiratory tract infection | 8% | 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Rhinitis | 1% - 36% | 1.22% - 23% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Akathisia | 0% - 16% | 0% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Oedema peripheral | 1% - 18% | 1% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Anxiety | frequent, 0% - 20% | 0% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Automatism | 7% | 1% | x | |||||||||||||||||||
Thirst | infrequent, 7% | 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Increased appetite | infrequent, 3.2% - 49% | 0% - 19% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Amenorrhoea | infrequent — 1% - 6.41% | 1% - 7.14% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Erectile dysfunction | infrequent — 1% - 10% | 1% - 7.14% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dizziness | 0.2% - 16% | 0% - 9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dyspepsia | 1% - 16% | 0% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Nasal congestion | 2% - 13% | 1.3% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Tremor | 0% - 24% | 0% - 16% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Malnutrition | postmarketing, 4% - 44% | 2% - 32% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Infection | 2% - 25% | 1% - 26% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Delusion | frequent | x | ||||||||||||||||||||
Menorrhagia | frequent | x | x | x | ||||||||||||||||||
Nausea | frequent, 0% - 16% | 0% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Polyuria | frequent | x | x | x | ||||||||||||||||||
Salivation | frequent | x | x | x | ||||||||||||||||||
Vomiting | frequent, 0% - 25% | 0% - 21% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Polydipsia | frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Injection site pain | frequent | x | ||||||||||||||||||||
Paranoid reaction | frequent | x | ||||||||||||||||||||
Vaginal dryness | frequent | x | ||||||||||||||||||||
Photosensitivity | frequent | x | ||||||||||||||||||||
Pharyngolaryngeal pain | 2.1% - 10% | 1.7% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Hypersomnia | frequent, 0.6% - 1.1% | 0.9% | x | x | x | x | x | x | x | |||||||||||||
Feeling abnormal | 0% - 5% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Somnolence | 0% - 67% | 0% - 23% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Rash | frequent, 0% - 11% | 0.9% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Nasopharyngitis | 1% - 21% | 1% - 10% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Erythema | 4% | 4.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Dry mouth | 0% - 15% | 1% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hypertonia | frequent, 3.69% | 0.978% | x | x | x | x | x | |||||||||||||||
Unspecified disorder of skin and subcutaneous tissue | postmarketing, 0% - 52% | 2% - 53% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Blood and lymphatic system disorders | 3% - 4% | 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Cardiovascular disorder | 3.23% | 2.93% | x | x | x | x | x | |||||||||||||||
Arthralgia | frequent, 1.5% - 4% | 0% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Cough | 0% - 24% | 0% - 18% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Diarrhoea | infrequent, 0.5% - 8% | 1% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Fatigue | frequent, 0% - 42% | 0% - 19% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Mediastinal disorder | postmarketing, 3% - 49% | 5% - 50% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Pharyngitis | 0% - 6% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Upper respiratory tract infection | 0% - 34% | 1% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Vision blurred | 1% - 7% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Hyperkinesia | 0.6% - 8.53% | 0% - 2.44% | x | x | x | x | x | |||||||||||||||
Manic psychosis | infrequent, 3% - 8% | 2.69% - 6% | x | x | x | |||||||||||||||||
Parkinsonism | 0% - 28% | 0% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Confusional state | infrequent, 0% - 5% | 0% - 0.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Conjunctivitis | 2.7% | 1.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Disorder sight | 2.53% | 1.47% | x | x | x | x | x | |||||||||||||||
Dry skin | 0% - 4% | 0% - 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Hypertension | postmarketing — 1% - 3% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Back pain | frequent, 0% - 4% | 1% - 1.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Chest pain | frequent, 0.8% - 3% | 0.4% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Epistaxis | infrequent, 0.5% - 6% | 0% - 1.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Eye disorder | postmarketing, 0.4% - 13% | 0% - 14% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Body temperature increased | 0% - 20% | 0% - 19% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Lethargy | 0% - 7.6% | 0% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Muscle rigidity | 1% - 11% | 2% | x | x | x | x | ||||||||||||||||
Salivary hypersecretion | 0% - 22% | 0% - 6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Tooth disorder | 0% - 4% | 0% | x | |||||||||||||||||||
Urinary tract infection | 0.5% - 12.9% | 0% - 10.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Viral infection | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Weight increased | infrequent, 1% - 8% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Agitation | frequent, 0% - 26% | 0% - 20% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Creatine phosphokinase increased | 1% - 2% | 1% | x | |||||||||||||||||||
Bone pain | rare — 1% - 2% | 1% | x | x | ||||||||||||||||||
Upset stomach | 0% - 6% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Blood prolactin increased | 0% - 3.8% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Pain | 1% - 10% | 0% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Myalgia | infrequent, 0% - 5% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Abnormal vision | 0% - 7% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Posture abnormal | 0% - 1.8% | 0.8% | x | x | x | x | x | x | x | x | ||||||||||||
Cardiac disorder | postmarketing, 1% - 7% | 0% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Suicide attempt | 1% - 2% | 1% - 3% | x | x | x | x | ||||||||||||||||
Angiopathy | postmarketing, 1% - 55% | 0% - 56% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Joint swelling | 1.5% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Visual acuity reduced | 0% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Pitting edema | 1.5% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Blood creatine phosphokinase increased | 0.4% - 2% | 0.1% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Sinusitis | 0% - 4% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Tachycardia | frequent, 0% - 7% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Depressed level of consciousness | 1.3% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Galactorrhoea | infrequent, 0.6% - 5% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Muscle contractions involuntary | infrequent, 1.15% | 0.244% | x | x | x | x | x | x | ||||||||||||||
Cellulitis | postmarketing, 1.1% | 1.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Apathy | infrequent — 0.9% - 1.1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Disturbance in attention | 0.9% - 4% | 0% - 0.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Abdominal pain | frequent, 0% - 18% | 0% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Anorexia | infrequent — 0% - 8% | 0% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Arrhythmia | 0% - 1% | 0% | x | x | x | |||||||||||||||||
Asthenia | frequent, 0% - 4% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Ataxia | infrequent, 1% | x | x | x | x | x | ||||||||||||||||
Dyskinesia | infrequent, 1% - 7% | 0% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dyspnoea | frequent, 0% - 5% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Ear pain | 0.1% - 1% | 0% - 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Oedema | postmarketing — 1% - 1.15% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gynaecomastia | postmarketing, 0% - 2.56% | 1% - 7.14% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Hypotension | infrequent — 0% - 5% | 0% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Leg pain | 1% - 4% | 1% | x | x | ||||||||||||||||||
Nervousness | frequent, 0.4% - 2% | 0.1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Pain in extremity | 1% - 6% | 1% - 2.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Palpitations | infrequent, 0.6% - 2.1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Psychotic disorder | postmarketing — 1% | 0% | x | x | ||||||||||||||||||
Syncope | 0% - 2% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Toothache | 0% - 4% | 0% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Urinary incontinence | postmarketing — 0% - 22% | 0% - 20% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Weight decreased | infrequent, 1% - 4% | 1% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Bundle branch block right | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Oculogyric crisis | infrequent, 1% | 1% | x | x | x | x | ||||||||||||||||
Hypokinesia | infrequent, 1% - 7% | 0% - 1% | x | x | x | x | x | x | ||||||||||||||
Joint stiffness | 1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Dandruff | 0.2% - 1% | 0% | x | x | x | x | x | |||||||||||||||
Decreased appetite | 0% - 6% | 1% - 1.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Abdominal discomfort | 1% - 3% | 0.9% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Sexual dysfunction | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Balance disorder | 0.9% - 1.1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Acne | 0% - 2% | 0% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Aggressive reaction | 1% - 3% | 1% - 3% | x | x | x | |||||||||||||||||
Sluggishness | 0.9% - 1.1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Influenza | 0% - 1.7% | 1.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Middle insomnia | 0% - 1.7% | 0.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Sinus congestion | 0% - 2% | 0% - 0.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Neck pain | 0.3% - 1.1% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Chest discomfort | 0.3% - 1.1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Pulmonary congestion | 0.3% - 1.1% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Amnesia | infrequent | x | x | |||||||||||||||||||
Anaemia | infrequent, 0.1% - 1% | 0% - 0.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hypochromic anaemia | infrequent | x | ||||||||||||||||||||
Apraxia | infrequent | x | ||||||||||||||||||||
Arthritis | rare, infrequent | x | x | |||||||||||||||||||
Atrioventricular block | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Bronchospasm | infrequent | x | ||||||||||||||||||||
Bundle branch block | infrequent | x | x | |||||||||||||||||||
Choking | infrequent | x | ||||||||||||||||||||
Colitis | infrequent | x | ||||||||||||||||||||
Libido decreased | infrequent, 1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dysphagia | infrequent, 1.5% | 1.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Delirium | rare, infrequent | x | x | |||||||||||||||||||
Depersonalisation | infrequent | x | ||||||||||||||||||||
Dermatitis | infrequent | x | ||||||||||||||||||||
Dysarthria | infrequent, 1.1% - 1.5% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Dysmenorrhoea | infrequent | x | x | |||||||||||||||||||
Dysuria | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Eczema | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Faecal incontinence | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Flatulence | infrequent | x | x | x | x | |||||||||||||||||
Gastritis | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Gastrooesophageal reflux disease | rare, infrequent | x | x | |||||||||||||||||||
Gingivitis | rare, infrequent | x | x | |||||||||||||||||||
Haematuria | infrequent | x | x | |||||||||||||||||||
Haemoptysis | infrequent | x | ||||||||||||||||||||
Haemorrhoids | infrequent | x | x | |||||||||||||||||||
Hepatomegaly | infrequent | x | ||||||||||||||||||||
Hyperventilation | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hyponatraemia | infrequent | x | x | |||||||||||||||||||
Libido increased | infrequent | x | x | x | ||||||||||||||||||
Irritable bowel syndrome | infrequent | x | ||||||||||||||||||||
Arthropathy | rare, infrequent | x | x | |||||||||||||||||||
Cramps of lower extremities | rare, infrequent | x | x | x | ||||||||||||||||||
Leukorrhea | infrequent | x | x | x | ||||||||||||||||||
Mastitis | infrequent | x | ||||||||||||||||||||
Breast pain | infrequent | x | ||||||||||||||||||||
Melaena | infrequent | x | x | |||||||||||||||||||
Metrorrhagia | infrequent | x | ||||||||||||||||||||
Myocardial infarction | infrequent | x | x | |||||||||||||||||||
Nightmare | rare, infrequent | x | x | x | ||||||||||||||||||
Paraesthesia | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Phlebitis | infrequent | x | ||||||||||||||||||||
Pneumonia | infrequent, 3.1% | 2.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Pruritus | infrequent, 0% - 2% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Purpura | infrequent | x | x | x | x | x | ||||||||||||||||
Seborrhoeic dermatitis | infrequent, 0% - 2% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Convulsion | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Gastric ulcer | infrequent | x | ||||||||||||||||||||
Stomatitis | infrequent | x | x | |||||||||||||||||||
Ulcerative stomatitis | infrequent | x | ||||||||||||||||||||
Stridor | infrequent | x | x | |||||||||||||||||||
Tendonitis | infrequent | x | ||||||||||||||||||||
Tetany | infrequent | x | x | |||||||||||||||||||
Torticollis | rare, infrequent | x | x | x | x | |||||||||||||||||
Pollakiuria | infrequent, 1.1% - 1.5% | 0.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Vaginal inflammation | infrequent | x | ||||||||||||||||||||
Vertigo | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Xerophthalmia | infrequent | x | x | |||||||||||||||||||
Stupor | infrequent | x | x | |||||||||||||||||||
Mood swings | rare, infrequent | x | x | x | ||||||||||||||||||
Migraine | rare, infrequent | x | x | |||||||||||||||||||
Injection site reaction | postmarketing, infrequent | x | x | x | ||||||||||||||||||
Muscular weakness | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Accommodation disorder | infrequent | x | x | |||||||||||||||||||
Photosensitivity reaction | infrequent | x | ||||||||||||||||||||
Malaise | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Bradykinesia | infrequent, 0% - 3% | x | x | x | ||||||||||||||||||
Rash erythematous | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Euphoric mood | infrequent | x | x | |||||||||||||||||||
Cerebration impaired | infrequent, 0% - 2% | 0% - 1% | x | x | x | x | x | |||||||||||||||
Lymphadenopathy cervical | infrequent | x | ||||||||||||||||||||
Skin exfoliation | infrequent | x | x | |||||||||||||||||||
Perineal pain | infrequent | x | ||||||||||||||||||||
Rectal haemorrhage | infrequent | x | ||||||||||||||||||||
Psychotic depression | infrequent | x | ||||||||||||||||||||
Ejaculation failure | infrequent, 0.4% - 1% | 0% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Influenza-like symptoms | infrequent | x | x | |||||||||||||||||||
Rigors | infrequent | x | x | |||||||||||||||||||
Bradycardia | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Lymphadenopathy | rare, infrequent | x | x | |||||||||||||||||||
Breast pain female | infrequent | x | ||||||||||||||||||||
Sweating decreased | infrequent | x | ||||||||||||||||||||
Renal pain | infrequent | x | ||||||||||||||||||||
Gait disturbance | infrequent, 0% - 4% | 1.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Sweating increased | infrequent | x | x | |||||||||||||||||||
Hyperkeratosis | infrequent, 0% - 1% | 0.3% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Vaginal haemorrhage | infrequent | x | ||||||||||||||||||||
Catatonic reaction | infrequent | x | ||||||||||||||||||||
Electrocardiogram QT prolonged | postmarketing, 1% | x | ||||||||||||||||||||
Hypersensitivity | postmarketing — 0.1% - 1% | 0% - 0.1% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Orthostatic hypotension | infrequent, 0% - 3% | 0% - 0.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Menstrual disorder | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Muscle twitching | 0% - 1% | x | ||||||||||||||||||||
Aspartate aminotransferase increased | rare — 0.2% - 1.15% | 0.2% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Alanine aminotransferase increased | infrequent, 0.2% | 0.2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Abscess | postmarketing | x | ||||||||||||||||||||
Agranulocytosis | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Alopecia | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Anaphylactic shock | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Angina pectoris | rare | x | x | |||||||||||||||||||
Angioedema | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Aphasia | rare | x | ||||||||||||||||||||
Apnoea | postmarketing | x | x | x | x | |||||||||||||||||
Ascites | rare | x | ||||||||||||||||||||
Asthma | rare | x | ||||||||||||||||||||
Atrial fibrillation | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Bipolar disorder | postmarketing | |||||||||||||||||||||
Blepharitis | rare | x | ||||||||||||||||||||
Breast disorder | postmarketing, 45% - 46% | 47% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Bursitis | rare | x | ||||||||||||||||||||
Cachexia | rare | x | ||||||||||||||||||||
Transient ischaemic attack | postmarketing, 1.6% | 0.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Cerebrovascular disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Cholecystitis | rare | x | ||||||||||||||||||||
Cholelithiasis | rare | x | ||||||||||||||||||||
Coma | rare | x | x | |||||||||||||||||||
Cystitis | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Sudden death | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dehydration | rare | x | x | |||||||||||||||||||
Diabetes mellitus | postmarketing, infrequent | x | x | x | x | x | x | |||||||||||||||
Diabetic ketoacidosis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Diplopia | rare | x | ||||||||||||||||||||
Diverticulitis | rare | x | ||||||||||||||||||||
Dysgeusia | postmarketing | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Endocrine disorder | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Eructation | rare | x | ||||||||||||||||||||
Oesophagitis | rare | x | ||||||||||||||||||||
Liver fatty | rare | x | ||||||||||||||||||||
Flushing | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Foramen ovale patent | postmarketing | x | ||||||||||||||||||||
Furunculosis | rare | x | ||||||||||||||||||||
Gastroenteritis | rare | x | x | x | x | x | x | x | x | |||||||||||||
Gastrointestinal disorder | postmarketing, 0% - 16% | 2% - 17% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Gastrointestinal haemorrhage | rare | x | ||||||||||||||||||||
Cardiac arrest | postmarketing | |||||||||||||||||||||
Haematemesis | rare | x | ||||||||||||||||||||
Blood disorder | postmarketing | x | x | x | ||||||||||||||||||
Haematoma | postmarketing, rare | x | ||||||||||||||||||||
Haemorrhage | rare | x | x | x | ||||||||||||||||||
Hepatitis | rare | x | x | |||||||||||||||||||
Hereditary angioedema | postmarketing | |||||||||||||||||||||
Hyperbilirubinaemia | rare | x | ||||||||||||||||||||
Hyperglycaemia | postmarketing, 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hypertrichosis | rare | x | ||||||||||||||||||||
Hypertriglyceridaemia | rare | x | ||||||||||||||||||||
Hypoaesthesia | rare, 0% - 2% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Hypoglycaemia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Hypokalaemia | rare | x | x | |||||||||||||||||||
Hypoproteinaemia | rare | x | ||||||||||||||||||||
Body temperature decreased | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Inappropriate antidiuretic hormone secretion | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Intermittent claudication | rare | x | ||||||||||||||||||||
Intestinal obstruction | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Jaundice | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Laryngeal oedema | postmarketing | |||||||||||||||||||||
Leukocytosis | rare | x | x | |||||||||||||||||||
Leukopenia | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Long QT syndrome | postmarketing | |||||||||||||||||||||
Lymphopenia | rare | x | ||||||||||||||||||||
Hypotonia | rare | x | ||||||||||||||||||||
Myocarditis | rare | x | ||||||||||||||||||||
Necrosis | postmarketing | |||||||||||||||||||||
Drug withdrawal syndrome neonatal | postmarketing | x | x | x | x | |||||||||||||||||
Neuroleptic malignant syndrome | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Neutropenia | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Nodule | postmarketing | |||||||||||||||||||||
Pallor | rare | x | ||||||||||||||||||||
Pancreatitis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Pituitary adenoma | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Pregnancy | postmarketing | x | ||||||||||||||||||||
Supraventricular extrasystoles | rare | x | ||||||||||||||||||||
Priapism | postmarketing | x | x | x | x | x |