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Rivastigmine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: N06DA03

Side effects

Options: Show MedDRA Preferred Terms,   display all 23 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Appetite absent very common x x x x
Nausea very rare — 1% - 47% 0% - 12% x x x x x x x x x x x x x x x x x x
Diarrhoea common — 1% - 19% 1% - 11% x x x x x x x x x x x
Tremor common — 1% - 23% 1% - 4% x x x x x x x x x x x x x x x x x x x x
Application site erythema common, 1% - 13% x x x x
Anaemia frequent x x x x x x x x
Angina pectoris frequent x x x x x x x x x x x x x x x x x x x x
Arthralgia infrequent, frequent x x x x x x x x x
Arthritis frequent x x x x x x
Ataxia frequent x x x x x x x
Atrial fibrillation postmarketing — frequent x x x x x x x x x x x x x x x x x x x x
Back pain frequent x x x x x x x x
Bronchitis frequent x x x x x x x
Basal cell carcinoma frequent x
Transient ischaemic attack frequent x x x x x x
Cerebrovascular disorder frequent x
Chest pain rare — frequent x x x x x x x x x x x
Infection frequent x x x x x x x x x x x x x x x x x x
Confusional state uncommon — 8% 7% x x x x x x x x x x x x x x x x x x x x
Constipation frequent, 5% 4% x x x x x x x x x x x
Dehydration postmarketing — 1% - 2% 1% x x x x x x x x x x x x x x x x x x x x
Depression common, 2% - 6% 1% - 4% x x x x x x x x x x x x x x x x x
Dyskinesia common — 3% 1% x x x x x x x x x x x x
Dyspepsia common — 8% - 9% 4% x x x x x x x x x x x x x x x x x x
Dyspnoea infrequent — 2% 1% x x x x x x x x x
Eczema infrequent, frequent x x x x x x x x x x
Oedema infrequent — frequent x x x x x x x x x x
Epistaxis frequent x x x x x x
Rash postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Extrapyramidal disorder frequent 0% x
Faecal incontinence frequent x x x x x x
Body temperature increased frequent x x x x x x x x x x x
Fracture frequent x x x x x x x
Gastritis infrequent, frequent x x x x x x x x x x
Cardiac failure frequent x x x x x x x x x
Haematuria infrequent, frequent x x x x x x x x x
Hypersensitivity infrequent, frequent x x x x x x x
Hypokalaemia infrequent, frequent x x x x x x x x x x
Hypotension infrequent — frequent x x x x x x x x x x x x x x
Orthostatic hypotension frequent x x x x x x x
Cramps of lower extremities frequent x x x x x x
Leg pain frequent x
Myocardial infarction frequent x x x x x x x x x x x x x x
Nasopharyngitis frequent x x
Nightmare frequent x
Palpitations frequent x x x x x x x
Paraesthesia frequent x x x x x x x
Pharyngitis frequent x x x x x x x
Pneumonia frequent x x x
Prostatic disorder frequent x
Convulsion postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Sinusitis frequent x
Skin disorder frequent x
Tinnitus infrequent, frequent x x x x x x x x x x
Tooth disorder frequent x
Upper respiratory tract infection frequent x x x x x x x
Urinary tract infection very rare — 1% - 10% 1% - 6% x x x x x x x x x x x x x x x x x x x x
Vertigo frequent, 0% - 2% 1% x x x x x x x x x x
Viral infection frequent x
Vomiting very rare — 0.4% - 31% 0% - 6% x x x x x x x x x x x x x x x x x x
Trauma frequent, 10% 9% x x x x x x x
Agitation postmarketing — 1% - 14% 2% x x x x x x x x x x x x x x x x x x x x
Oedema peripheral frequent x x x x x x x x x
Cataract frequent x x x x x x x x x
Paranoid reaction frequent x x x x x x x
Malaise uncommon — 4% - 5% 2% x x x x x x x x x x x x x x x x x
Myalgia infrequent, frequent x x x x x x x x
Decreased appetite frequent, 1% - 9% 1% - 5% x x x
Hallucination, visual frequent x
Trembling common x x
Rigors frequent 0% x x x x x x x x x x x
Bradycardia infrequent — frequent x x x x x x x x x x x x x x x x x x x x
Gait disturbance frequent, 4% 0% x x x x x x x x x x x x x
Hot flush frequent x x x x x x x
Somnolence uncommon — 1% - 6% 1% - 3% x x x x x x x x x x x x x x x x x x
Abdominal pain common, 1% - 13% 1% - 6% x x x x x x x x x x x x x x x x x x x x
Anxiety common, 1% - 5% 1% - 3% x x x x x x x x x x x x x x x x x x x x
Fatigue common, 0% - 9% 0% - 5% x x x x x x x x x x x x x x x x x x x x
Flatulence frequent, 4% 2% x x x x x x x x
Hallucination very rare — 2% - 5% 3% x x x x x x x x x x x x x x x x x x x
Headache common, 1% - 17% 2% - 12% x x x x x x x x x x x x x x x x x x x x
Nervousness 4% 3% x x x x x x x
Rhinitis 4% 3% x x x x x x x
Abdominal pain upper 1% - 4% 1% - 2% x x x x x x x x x
Sweating increased common — 2% - 4% 1% x x x x x x x x x x x
Anorexia 1% - 17% 0% - 3% x x x x x x x x x x x x x x x x x x x
Cardiovascular disorder 3% 2% x x x x x x x x
Dizziness common, 0% - 21% 0% - 11% x x x x x x x x x x x x x x x x x x x x
Hypertension very rare — 1% - 3% 2% x x x x x x x x x x x x x x x x x x x x
Parkinson's disease postmarketing — 3% 1% x x x x x x
Syncope uncommon — 3% 2% x x x x x x x x x x x x x x x x x x x x
Weight decreased common — 1% - 8% 0% - 1% x x x x x x x x x x x x x x x x x x x x
Cogwheel rigidity common, 3% 0% x x x x x x
Bradykinesia common — 2% - 4% 2% x x x x x x x x x x x x
Influenza-like symptoms frequent, 3% 2% x x x x x x x
Insomnia infrequent — 1% - 9% 2% - 7% x x x x x x x x x x x x x x x x x x x x
Aggressive reaction 3% 2% x x x x x x x x
Conjunctivitis infrequent, frequent x x x x x
Pain infrequent, frequent x x x x x x x x x x
Application site pruritus common, 1% - 4% x x x x x
Asthenia common, 0% - 6% 0% - 2% x x x x x x x x x x x x x x x x x x x x
Eructation 2% 1% x x x x x x x
Hyperhidrosis uncommon — 2% 1% x x x x x x x x x x
Pruritus postmarketing — 1.7% - 2% 1% x x x x x x x x x x x x x x
Pollakiuria infrequent, 2% 1% x x x
Parkinsonism 2% 1% x x x x x x x x x x x x x
Abnormal vision 2% 1% x
Urinary incontinence infrequent — 1% - 3% 2% x x x x x x x x x x x x x x x x
Aggression postmarketing — 0.4% - 3% x x x x x x x x x x x x
Abscess infrequent x
Adams-Stokes syndrome infrequent x x x x x
Adenocarcinoma infrequent x
Albuminuria infrequent x x x x x x
Alopecia infrequent x x x x x x
Amnesia infrequent x x x x x x
Hypochromic anaemia infrequent x x x x x x
Aneurysm infrequent x x x x x x
Aphasia infrequent x x x x x x
Apnoea infrequent x x x x x x
Apraxia infrequent x x x x x x
Arrhythmia very rare — uncommon x x x x x x x x x x x x x
Rheumatoid arthritis infrequent x
Atrioventricular block postmarketing — uncommon x x x x x x x x x x x x x x x x x x x x
Bacterial infection infrequent x
Bladder disorder infrequent x
Neurogenic bladder infrequent x x x x x
Blepharitis infrequent x x x x x x
Blepharospasm infrequent x x x x x
Bone disorder infrequent x
Brain disorder NOS uncommon x
Breast cancer infrequent x
Bronchospasm infrequent x x x x x x x x x x
Bundle branch block infrequent x x x x x x
Bursitis infrequent x
Cachexia infrequent x x x x x x
Candida infection infrequent x
Carcinoma infrequent x
Skin cancer infrequent x
Cellulitis infrequent x x x x x x
Cholecystitis infrequent x x x x x x x x
Cholelithiasis infrequent x
Colitis infrequent x x x x x x
Coma infrequent x
Conjunctival haemorrhage infrequent x x x x x x
Cough infrequent, frequent x x x x x x x x
Cystitis infrequent x x x x x x
Deafness infrequent x
Libido decreased infrequent x x x x x x
Dysphagia infrequent x x x x x x x
Delirium infrequent, uncommon x x x x x x x x x x x x x x x x
Delusion infrequent, frequent x x x x x x x x x
Dental caries infrequent x
Depersonalisation infrequent x x x x x x
Dermatitis infrequent x x x x
Dermatitis contact infrequent, uncommon x x x x x x x x x
Diabetes mellitus infrequent x x x x x x
Diplopia infrequent x x x x x x x
Diverticulitis infrequent x x x x x x x
Drowsiness uncommon x
Duodenal ulcer rare, infrequent x x x x x x x x x x x x x x x x x x x
Dysgeusia infrequent x x x x x x
Dysuria infrequent x x x x x x x
Ear disorder infrequent x
Ear pain infrequent x
Epilepsy infrequent x x x x x x x
Oesophagitis infrequent x x x x x x
Congenital eye disorder infrequent x
Eyelid disorder infrequent x
Flushing infrequent x x x x x x
Furunculosis infrequent x
Gastroenteritis infrequent x x x x x x
Gastrooesophageal reflux disease infrequent x x x x x x x x x x
Gastrointestinal haemorrhage very rare — uncommon x x x x x x x x x x x x x x x x x x
Gingivitis infrequent x x x x x x
Glaucoma infrequent x x x x x x x x x
Glossitis infrequent x x x x x x
Goitre infrequent x x x x x x
Gout infrequent x x x x x x
Breath odour infrequent x x x x x x
Cardiac arrest infrequent x x x x x x
Haematemesis infrequent x x x x x x x x x x
Haematochezia infrequent x x x
Haematoma infrequent, frequent x x x x x x
Subdural haematoma infrequent x x
Hemiparesis infrequent x x x x x
Haemorrhage infrequent x x x x x x
Haemorrhoids infrequent x x x x x x
Hernia infrequent x x x x x x x
Herpes simplex infrequent x x x x x x x
Herpes zoster infrequent x
Hiccups infrequent x
Hip fracture infrequent x x x
Hypercholesterolaemia infrequent x x x x x x
Hyperglycaemia infrequent x x x x x x
Hyperlipidaemia infrequent x x x x x x x
Hyperventilation infrequent x
Hypoaesthesia infrequent x x x x x x x
Hypoglycaemia infrequent x x x x x x
Hyponatraemia infrequent x x x x x x x x x x
Body temperature decreased infrequent x x x x x x
Hypothyroidism infrequent x x x x x x
Libido increased infrequent x x x x x x x
Inflammation infrequent x
Intestinal obstruction infrequent x x x x x x
Arthropathy infrequent x
Calculus of kidney infrequent x x x x x x
Renal failure acute infrequent x x x x x x x
Laryngitis infrequent x x x x x x
Leukocytosis infrequent x x x x x x
Lung disorder infrequent x
Mastitis infrequent x x x x x
Breast pain infrequent x x x x x x x
Melaena infrequent x x x x x x x
Meniere's disease infrequent x x x x x
Metrorrhagia infrequent x
Cramp muscle infrequent x x x x x x
Hypertonia infrequent x x x x x x
Fungal infection infrequent x
Myoclonus infrequent x x x x x
Nail disorder infrequent x
Neoplasm infrequent x
Neuralgia infrequent x x x x x x
Neurosis infrequent x x x x x x
Nocturia infrequent x x x x x x x x
Nystagmus infrequent x x x x x x x
Oliguria infrequent x x x x x
Osteoporosis infrequent x
Otitis externa infrequent x
Otitis media infrequent x x x x x x x
Pallor infrequent x
Pancreatitis very rare — infrequent x x x x x x x x x x x x x x x x x x x x
Paresis infrequent x x x x x x
Peptic ulcer infrequent x x x
Neuropathy peripheral infrequent x x x x x x
Peritonitis infrequent x x x x x
Personality disorder infrequent x x x x x
Phlebitis infrequent x
Pleural effusion infrequent x
Polyuria infrequent x x x x x x
Supraventricular extrasystoles infrequent x x x x x
Pruritus genital infrequent x
Psychotic disorder infrequent x x x x x x
Pulmonary oedema infrequent x
Pulmonary embolism infrequent x x x x x x
Emphysema infrequent x
Purpura infrequent, frequent x x x x x x
Pyuria infrequent x
Rectal disorder infrequent x
Renal failure infrequent x x
Respiratory insufficiency infrequent x
Restless legs syndrome infrequent x x x x x
Retinal disorder infrequent x x x x x
Seborrhoeic dermatitis infrequent x
Salivary hypersecretion infrequent — 2% 0% x x x x x x x x x x x x x x x
Sick sinus syndrome postmarketing, infrequent x x x x x x x x x x x x x x x x x
Skin ulcer infrequent, frequent x x x x x x x x x
Muscle spasms infrequent x x
Speech disorder infrequent x
Gastric ulcer infrequent, uncommon x x x x x x x x x x x
Ulcerative stomatitis infrequent x x x x x x
Cerebrovascular accident infrequent, uncommon x x x x x x
Suicide attempt infrequent x x x x x x
Sunburn infrequent x
Sweating uncommon x
Tachycardia postmarketing, infrequent x x x x x x x x x x x x x x x x x x x x
Supraventricular tachycardia infrequent x x x x x x x
Tendonitis infrequent x
Thirst infrequent x x x x x x
Thrombocytopenia infrequent, frequent x x x x x x
Thrombophlebitis infrequent x x x x x x
Thrombosis infrequent x x x x x x
Onychomycosis infrequent x
Erythema postmarketing — 1.1% x x x x x x x x x x
Urethral disorder infrequent x
Micturition disorder infrequent x
Urticaria postmarketing, infrequent x x x x x x x x x x x x x x x
Uterine disorder infrequent x
Vaginal inflammation infrequent x
Varicose vein infrequent x
Angiopathy infrequent x x x x x x x x x x x
Vasculitis infrequent x x x x x
Syncope vasovagal infrequent x x x x x
Vestibular disorder infrequent x
Common wart infrequent x
Weight increased infrequent x
Dry mouth infrequent x x x x x x
Urinary retention infrequent x x x x x x
Sudden cardiac death infrequent x x x x x
Micturition urgency infrequent x x x x x x
Apathy infrequent x x x x x x x
Mood swings infrequent x x x x x x
Hypokinesia infrequent — 2% - 4% 0% x x x x x x x x x x x x x
Migraine infrequent x x x x x x x x x x
Periorbital oedema infrequent x x x x x x
Generalised oedema infrequent x
Haemorrhage intracranial infrequent x x x x x x
Skin hypertrophy infrequent x
Myocardial ischaemia infrequent x
Kidney function abnormal infrequent x
Muscular weakness infrequent x x x x x x x
Bone pain infrequent x
Retrosternal pain infrequent x
Eye pain infrequent x x x x x x
Phosphatase alkaline increased infrequent x x x x x
Electrocardiogram QT prolonged infrequent x x x
Hyporeflexia infrequent x
Hyperreflexia infrequent x x x x x x
Skin discolouration infrequent x
Dry skin infrequent x
Tendon disorder infrequent x
Spine malformation infrequent x
Abnormal chest sounds NOS infrequent x
Muscle stiffness infrequent x x x x x x
Vaginitis atrophic infrequent x x x x x x
Increased appetite infrequent x
Rectal tenesmus infrequent x x x x x x
Rash erythematous infrequent x x x x
Muscle contractions involuntary infrequent x
Cerebration impaired infrequent x x x x x x
Peripheral ischaemia infrequent x x x x x x x
Bullous eruption infrequent x
Skin cold clammy infrequent x x x x x x
Lacrimation abnormal NOS infrequent x
Skin exfoliation infrequent x
Dermal cyst infrequent x
Erectile dysfunction infrequent x x x x x x
Sepsis infrequent x
Rectal haemorrhage infrequent x x x x x x x
Extrasystoles infrequent x x x x x x x
Vision blurred infrequent x x x x x x x x x
Rash maculo-papular infrequent x
Suicidal ideation infrequent x x x x x x x
Hyperkinesia infrequent x x x x x x
Stiffness infrequent x
Neuropathy infrequent x
Lymphadenopathy infrequent x x x x x x x
Dementia infrequent x x x x x
Prostatic adenoma infrequent x x x x x
Coordination abnormal infrequent x
Congenital joint malformation infrequent x
Electrocardiogram abnormal infrequent x
Face oedema infrequent x
Lipase increased infrequent x x x
Heart sounds abnormal infrequent x
Carcinoma colon infrequent x
Bladder carcinoma infrequent x
Unspecified circulatory system disorder infrequent x
Infection parasitic infrequent x
Increased prolactin level infrequent x x x x x
Sleep disorder infrequent x
Blood amylase increased infrequent x x x
Blood creatine phosphokinase increased infrequent x x x
Unwell uncommon x
Endometrial hypertrophy infrequent x x x x x
Hyperkeratosis infrequent x
Large intestine polyp infrequent x
Freezing phenomenon infrequent x x x x x
Dysphonia infrequent x x x x x x x
Coronary artery disease infrequent x
Anaemia vitamin B12 deficiency infrequent x
Renal cyst infrequent x
Ageusia infrequent x x x x x x
Vaginal haemorrhage infrequent x
Mental disorder postmarketing x x x x x x x x x x x x x x x x x x x x
Blister postmarketing x x x x x
Dermatitis atopic postmarketing x x x x x x x x
Cardiac disorder postmarketing x x x x x x x x x x x x
Hepatitis postmarketing x x x x x x x x x x x
Stevens-Johnson syndrome postmarketing x x x x x x x
Liver function test abnormal postmarketing x x x
Malnutrition postmarketing x x x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x x x x x x x x x
Hepatobiliary disease postmarketing x x x x x x x x