Options: Show MedDRA Preferred Terms, display all 40 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Neoplasm malignant aggravated | 17% - 20% | 20% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Anaemia | postmarketing — 4.4% - 22% | 3.6% - 5.2% | x | x | x | x | x | x | x | |||||||||||||
Urinary tract infection | 12% - 15% | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Insomnia | 10% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Pain in extremity | 3.9% - 16% | 4.8% - 9.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Confusional state | rare, 11% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Cough | uncommon, 10% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hypokalaemia | uncommon, 10% - 16% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Agitation | 8% - 11% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Headache | postmarketing — 3.9% - 20.4% | 2.5% - 11.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Anxiety | uncommon, 8% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Osteoarthritis | 5.7% - 9.1% | 4.5% - 9.7% | x | x | ||||||||||||||||||
Candida infection | 4% - 12% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Hypophosphataemia | common — 1% - 51% | 0.2% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Hypertension | uncommon — 5.1% - 12.7% | 5.4% - 12.4% | x | x | x | x | x | x | ||||||||||||||
Influenza | 5% - 7% | x | x | x | x | x | x | x | ||||||||||||||
Constipation | uncommon — 5% - 23% | 6.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Diarrhoea | postmarketing — 5.2% - 17% | 4.7% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Nausea | postmarketing — 4.5% - 28% | 4.5% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Non-cardiac chest pain | 3.5% - 7.7% | 3% | x | x | x | |||||||||||||||||
Back pain | 1.7% - 18.2% | 11.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Arthralgia | postmarketing — 3% - 27.3% | 18.3% - 20.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Dyspnoea | uncommon — 1% - 20% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Oesophagitis | common | x | x | |||||||||||||||||||
Flushing | common | x | x | x | x | x | ||||||||||||||||
Nasopharyngitis | common | x | x | x | ||||||||||||||||||
Pain | uncommon — 1.5% - 24.2% | 0.5% - 3.5% | x | x | x | x | x | x | x | x | x | |||||||||||
Tachycardia | common | |||||||||||||||||||||
Thirst | common | x | x | |||||||||||||||||||
Blood urea increased | common | x | ||||||||||||||||||||
Bone pain | postmarketing — 3.2% - 12% | 1% - 2.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Rigors | common, 1% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Stiffness | common | x | ||||||||||||||||||||
Musculoskeletal chest pain | common | x | x | x | ||||||||||||||||||
Renal impairment | postmarketing, common | x | ||||||||||||||||||||
Neck pain | 1.4% - 6.6% | 1.1% - 5% | x | x | x | x | ||||||||||||||||
Breast cancer | 4.3% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Joint stiffness | common, 1.1% - 3.5% | 2% | x | x | x | x | ||||||||||||||||
Infection | postmarketing, 4% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dizziness | uncommon, 2% - 9% | 3.5% - 6.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dyspepsia | uncommon — 1.7% - 7.1% | 1.6% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Shoulder pain | 0% - 6.9% | 0% - 5.6% | x | x | x | x | ||||||||||||||||
Lethargy | common, 1% - 5% | x | x | x | x | x | x | x | ||||||||||||||
Muscle spasms | 1.5% - 5.6% | 1.7% - 5% | x | x | x | x | ||||||||||||||||
Neoplasm | 3.2% | x | ||||||||||||||||||||
Prostate cancer | 3.1% | x | x | |||||||||||||||||||
Oedema peripheral | uncommon — 1% - 5.6% | 3.5% - 5.3% | x | x | x | x | x | x | x | x | x | |||||||||||
C-reactive protein increased | 1.4% - 4.6% | x | x | x | ||||||||||||||||||
Pain in jaw | 2% - 3.9% | 2.5% | x | x | ||||||||||||||||||
Hyperhidrosis | common, 2% - 2.6% | x | x | x | x | |||||||||||||||||
Atrial fibrillation | uncommon, 2% - 3.3% | 1.9% - 2.6% | x | |||||||||||||||||||
Fatigue | postmarketing — 2.1% - 17.6% | 1.2% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Creatinine renal clearance decreased | 2% - 2.1% | 1.7% - 2.4% | x | |||||||||||||||||||
Myalgia | postmarketing — 4% - 22.7% | 2.7% - 6.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Abdominal pain | uncommon — 2% - 14% | 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Anorexia | common, 0.6% - 14% | 0% - 1.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Rash | uncommon, 2% - 3% | 2.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Body temperature increased | postmarketing — 0.3% - 38% | 0.1% - 4.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypotension | uncommon, 2% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Vomiting | postmarketing — 2% - 17% | 3.2% - 4.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Vertigo | 1.3% - 4.3% | 1% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Abdominal discomfort | 1.1% - 2% | 0.5% | x | |||||||||||||||||||
Abdominal distension | 0.6% - 2% | 0% | x | x | x | x | ||||||||||||||||
Abdominal pain upper | 0.9% - 4.6% | 1.5% - 3.1% | x | x | x | x | x | x | x | |||||||||||||
Musculoskeletal stiffness | 0% - 4.6% | x | x | x | x | x | x | |||||||||||||||
Blood creatinine increased | 0.7% - 2% | x | x | x | x | |||||||||||||||||
Flank pain | 0.6% - 2% | 0% | x | x | ||||||||||||||||||
Chest pain | uncommon, 1.3% - 2.4% | 1.1% - 1.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Palpitations | 0% - 2.6% | x | x | x | ||||||||||||||||||
Hypermagnesaemia | 1% - 2% | 0.5% - 2% | x | x | x | x | x | x | x | x | x | |||||||||||
Asthenia | postmarketing — 1% - 6.1% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Eye pain | 0% - 2% | x | x | x | ||||||||||||||||||
Hypoaesthesia | uncommon, 2.2% - 5.6% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Leukopenia | uncommon | x | x | |||||||||||||||||||
Paraesthesia | uncommon — 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Pruritus | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Sleep disturbance | uncommon | x | ||||||||||||||||||||
Stomatitis | uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Swelling | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Syncope | uncommon | x | x | x | ||||||||||||||||||
Thrombocytopenia | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Injection site reaction | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Rash macular | uncommon | x | x | |||||||||||||||||||
Induration | uncommon | x | x | |||||||||||||||||||
Redness | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Somnolence | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hypocalcaemia | very rare — 1% - 3% | 0.2% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypomagnesaemia | uncommon, 1% - 9% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Acute phase reaction | postmarketing — 0% - 3.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Anaphylactic shock | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Angioedema | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Arthritis | postmarketing — 2.2% - 4% | 1.5% | x | x | x | x | x | x | x | |||||||||||||
Coagulopathy | postmarketing | x | x | x | x | |||||||||||||||||
Bronchospasm | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Neoplasm malignant | postmarketing, 14% - 21% | x | x | x | x | x | x | x | x | x | ||||||||||||
Conjunctivitis | postmarketing, common | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dehydration | postmarketing, 0.6% - 2.5% | 0.6% - 2.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dysgeusia | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Oedema | postmarketing | x | x | x | ||||||||||||||||||
Episcleritis | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Femur fracture | postmarketing | x | x | x | x | x | x | x | x | x | ||||||||||||
Haematuria | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hyperaesthesia | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hyperkalaemia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hypernatraemia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hypersensitivity | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Inflammation | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Iridocyclitis | postmarketing | x | x | x | ||||||||||||||||||
Iritis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Renal failure acute | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | ||||||||||||
Oral disorder | postmarketing | x | x | |||||||||||||||||||
Plasma cell myeloma | postmarketing, 3.2% | x | x | x | x | x | x | x | x | x | ||||||||||||
Cramp muscle | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Musculoskeletal pain | postmarketing — 0.4% - 12.4% | 0.3% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Osteonecrosis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Pancytopenia | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Proteinuria | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Scleritis | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Shock | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Tremor | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Urticaria | postmarketing, uncommon | x | x | x | x | x | x | x | x | |||||||||||||
Uveitis | very rare — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Weight increased | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Dry mouth | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Bronchoconstriction | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Chills | postmarketing, 1.5% - 18.2% | 0.5% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Joint swelling | postmarketing — 0.6% - 3% | 0% | x | x | x | x | x | x | x | |||||||||||||
Interstitial lung disease | postmarketing, rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Fatal outcomes | postmarketing | x | x | |||||||||||||||||||
Malaise | postmarketing — 0.7% - 7.2% | 0.5% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Vision blurred | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Exacerbation of asthma | postmarketing | x | x | x | ||||||||||||||||||
Influenza-like symptoms | postmarketing, 6.7% - 8% | x | x | x | x | x | x | |||||||||||||||
Orbital oedema | postmarketing | x | x | x | x | x | x | x | ||||||||||||||
Bradycardia | rare | x | x | |||||||||||||||||||
Influenza like illness | postmarketing, 0.8% - 11% | 0.4% - 2.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Sweating increased | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | ||||||||||||
Osteonecrosis of jaw | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Advanced breast cancer | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Arrhythmia | very rare | x | ||||||||||||||||||||
Numbness | very rare | x | ||||||||||||||||||||
Convulsion | very rare | x | ||||||||||||||||||||
Tetany | very rare | x | ||||||||||||||||||||
Agranulocytosis | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Alopecia | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Atrial flutter | x | |||||||||||||||||||||
Mental disorder | x | x | x | x | ||||||||||||||||||
Bone disorder | x | x | x | x | x | x | ||||||||||||||||
Connective tissue disorder | x | x | x | x | x | |||||||||||||||||
Dysphagia | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Depression | x | x | x | x | x | x | x | x | ||||||||||||||
Dermatitis | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Endophthalmitis | x | x | ||||||||||||||||||||
Eye disorder | x | x | x | x | x | |||||||||||||||||
Gastritis | x | x | ||||||||||||||||||||
Gastrooesophageal reflux disease | x | x | ||||||||||||||||||||
Gastrointestinal disorder | x | x | x | x | x | x | x | x | x | |||||||||||||
Cardiac disorder | x | x | x | x | x | |||||||||||||||||
Hypogonadism | x | x | ||||||||||||||||||||
Immune system disorder | x | x | x | |||||||||||||||||||
Insomnia NEC | ||||||||||||||||||||||
Renal failure chronic | x | |||||||||||||||||||||
Mediastinal disorder | x | x | x | x | x | x | x | x | x | |||||||||||||
Musculoskeletal disorder | x | |||||||||||||||||||||
Necrosis ischaemic | x | |||||||||||||||||||||
Metastasis | x | x | x | |||||||||||||||||||
Nervous system disorder | x | x | x | x | x | x | x | x | x | |||||||||||||
Neutropenia | x | x | x | x | x | x | x | x | x | |||||||||||||
Night sweats | x | |||||||||||||||||||||
Osteomyelitis | x | x | x | |||||||||||||||||||
Osteopenia | x | x | ||||||||||||||||||||
Pleural effusion | x | x | x | |||||||||||||||||||
Renal failure | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Toothache | x | x | ||||||||||||||||||||
Erythema | x | x | ||||||||||||||||||||
Upper respiratory tract infection | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Pollakiuria | x | x | ||||||||||||||||||||
Urinary tract disorder | x | x | x | x | x | |||||||||||||||||
Angiopathy | x | x | x | x | x | |||||||||||||||||
Weight decreased | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Spinal fracture | ||||||||||||||||||||||
Cataract | x | |||||||||||||||||||||
Electrolyte abnormality | x | x | x | |||||||||||||||||||
Muscular weakness | x | x | ||||||||||||||||||||
Ocular hyperaemia | x | x | ||||||||||||||||||||
Malnutrition | x | x | x | x | x | x | x | |||||||||||||||
Unspecified disorder of skin and subcutaneous tissue | x | x | x | x | x | x | x | x | ||||||||||||||
Cardiac fibrillation | x | |||||||||||||||||||||
Decreased appetite | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Abdominal pain lower | x | |||||||||||||||||||||
Leg edema | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Creatinine low | x | |||||||||||||||||||||
Edema of lower extremities | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Throat sore | x | x | x | x | x | x | x | x | x | |||||||||||||
Azotaemia | x | |||||||||||||||||||||
Mucosal inflammation | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Anxiety depression | x | x | ||||||||||||||||||||
Serum creatinine abnormal | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Reaction gastrointestinal | x | x | x | x | ||||||||||||||||||
Nephropathy toxic | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Renal cancer | x | x | x | x | x | x | x | x | ||||||||||||||
Infestation NOS | x | x | x | x | x | x | x | |||||||||||||||
Blood and lymphatic system disorders | x | x | x | x | ||||||||||||||||||
Ear and labyrinth disorders | x | x | x | x | ||||||||||||||||||
Sleep disorder | x | |||||||||||||||||||||
Paraesthesia NEC | ||||||||||||||||||||||
Anxiety NEC | ||||||||||||||||||||||
Local reaction | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Infusion related reaction | x | |||||||||||||||||||||
Infusion site reaction | x | x | ||||||||||||||||||||
Bone mass decreased | x | |||||||||||||||||||||
Atypical femur fracture | x | |||||||||||||||||||||
Blood calcium decreased | x |
Information about indications was extracted from the indications and usage sections of the labels.
Indication | Labels | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Asthma | x | |||||||||||||||||||||
Asthma aspirin-sensitive | x | |||||||||||||||||||||
Atrial fibrillation | x | |||||||||||||||||||||
Bone cancer metastatic | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Cardiac failure | x | x | x | |||||||||||||||||||
Fracture | x | x | x | |||||||||||||||||||
Hip fracture | x | x | x | |||||||||||||||||||
Hydraemia | x | x | x | |||||||||||||||||||
Hypercalcaemia | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Hypercalcaemia of malignancy | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hyperparathyroidism | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Hypovolaemia | x | x | x | |||||||||||||||||||
Menopause | x | |||||||||||||||||||||
Neoplasm | x | x | x | x | x | x | ||||||||||||||||
Neoplasm malignant | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Osteitis deformans | x | x | x | x | x | x | ||||||||||||||||
Osteoporosis | x | x | x | x | ||||||||||||||||||
Osteoporosis postmenopausal | x | x | x | x | x | |||||||||||||||||
Plasma cell myeloma | x | x | x | x | x | x | x | x | x | |||||||||||||
Prostate cancer | x | x | x | x | x | x | x | x | x | |||||||||||||
Serum creatinine increased | x | |||||||||||||||||||||
Solid tumour | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Spinal cord compression | x | |||||||||||||||||||||
Spinal fracture | x | |||||||||||||||||||||
Trauma | x | |||||||||||||||||||||
Urine output | x | x | x |
standard – alternative
100% | ||
75% | ||
50% | ||
10% | ||
frequent (1% to 100%) | ||
infrequent (0.1% to 1%) | ||
rare (<0.1%) | ||
postmarketing | ||
0% | ||
no frequency information | ||
not found on label |