Options: Show MedDRA Preferred Terms, display all 40 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Neoplasm malignant aggravated | 17% - 20% | 20% | x | x | x | x | x | x | x | x | x | |||||||||||
Anaemia | postmarketing — 4.4% - 22% | 3.6% - 5.2% | x | x | x | x | x | |||||||||||||||
Urinary tract infection | 12% - 15% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Insomnia | 10% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Pain in extremity | 3.9% - 16% | 4.8% - 9.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Confusional state | rare, 11% - 13% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Cough | uncommon, 10% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Hypokalaemia | uncommon, 10% - 16% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Agitation | 8% - 11% | x | x | x | x | x | x | x | x | x | x | |||||||||||
Headache | postmarketing — 3.9% - 20.4% | 2.5% - 11.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Anxiety | uncommon, 8% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Osteoarthritis | 5.7% - 9.1% | 4.5% - 9.7% | x | x | ||||||||||||||||||
Candida infection | 4% - 12% | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hypophosphataemia | common — 1% - 51% | 0.2% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hypertension | uncommon — 5.1% - 12.7% | 5.4% - 12.4% | x | x | x | x | x | x | x | x | ||||||||||||
Influenza | 5% - 7% | x | x | x | x | x | x | |||||||||||||||
Constipation | uncommon — 5% - 23% | 6.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Diarrhoea | postmarketing — 5.2% - 17% | 4.7% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Nausea | postmarketing — 4.5% - 28% | 4.5% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Non-cardiac chest pain | 3.5% - 7.7% | 3% | x | x | x | |||||||||||||||||
Back pain | 1.7% - 18.2% | 11.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Arthralgia | postmarketing — 3% - 27.3% | 18.3% - 20.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Dyspnoea | uncommon — 1% - 20% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Oesophagitis | common | x | x | |||||||||||||||||||
Flushing | common | x | x | x | x | x | x | x | ||||||||||||||
Nasopharyngitis | common | x | x | x | x | x | ||||||||||||||||
Pain | uncommon — 1.5% - 24.2% | 0.5% - 3.5% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Tachycardia | common | x | x | |||||||||||||||||||
Thirst | common | x | x | |||||||||||||||||||
Blood urea increased | common | x | x | x | ||||||||||||||||||
Bone pain | postmarketing — 3.2% - 12% | 1% - 2.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Rigors | common, 1% - 8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Stiffness | common | |||||||||||||||||||||
Musculoskeletal chest pain | common | x | x | x | ||||||||||||||||||
Renal impairment | postmarketing, common | x | x | x | ||||||||||||||||||
Neck pain | 1.4% - 6.6% | 1.1% - 5% | x | x | x | x | ||||||||||||||||
Breast cancer | 4.3% | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Joint stiffness | common, 1.1% - 3.5% | 2% | x | x | x | x | ||||||||||||||||
Infection | postmarketing, 4% - 12% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dizziness | uncommon, 2% - 9% | 3.5% - 6.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dyspepsia | uncommon — 1.7% - 7.1% | 1.6% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Shoulder pain | 0% - 6.9% | 0% - 5.6% | x | x | x | x | ||||||||||||||||
Lethargy | common, 1% - 5% | x | x | x | x | x | x | |||||||||||||||
Muscle spasms | 1.5% - 5.6% | 1.7% - 5% | x | x | x | x | ||||||||||||||||
Neoplasm | 3.2% | x | x | x | ||||||||||||||||||
Prostate cancer | 3.1% | x | x | x | ||||||||||||||||||
Oedema peripheral | uncommon — 1% - 5.6% | 3.5% - 5.3% | x | x | x | x | x | x | x | x | x | x | ||||||||||
C-reactive protein increased | 1.4% - 4.6% | x | x | x | ||||||||||||||||||
Pain in jaw | 2% - 3.9% | 2.5% | x | |||||||||||||||||||
Hyperhidrosis | common, 2% - 2.6% | x | x | x | x | |||||||||||||||||
Atrial fibrillation | uncommon, 2% - 3.3% | 1.9% - 2.6% | x | x | ||||||||||||||||||
Fatigue | postmarketing — 2.1% - 17.6% | 1.2% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Creatinine renal clearance decreased | 2% - 2.1% | 1.7% - 2.4% | x | |||||||||||||||||||
Myalgia | postmarketing — 4% - 22.7% | 2.7% - 6.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Abdominal pain | uncommon — 2% - 14% | 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Anorexia | common, 0.6% - 14% | 0% - 1.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Rash | uncommon, 2% - 3% | 2.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Body temperature increased | postmarketing — 0.3% - 38% | 0.1% - 4.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypotension | uncommon, 2% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Vomiting | postmarketing — 2% - 17% | 3.2% - 4.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Vertigo | 1.3% - 4.3% | 1% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Abdominal discomfort | 1.1% - 2% | 0.5% | x | |||||||||||||||||||
Abdominal distension | 0.6% - 2% | 0% | x | x | x | |||||||||||||||||
Abdominal pain upper | 0.9% - 4.6% | 1.5% - 3.1% | x | x | x | x | x | x | ||||||||||||||
Musculoskeletal stiffness | 0% - 4.6% | x | x | x | x | x | ||||||||||||||||
Blood creatinine increased | 0.7% - 2% | x | x | x | x | |||||||||||||||||
Flank pain | 0.6% - 2% | 0% | x | |||||||||||||||||||
Chest pain | uncommon, 1.3% - 2.4% | 1.1% - 1.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Palpitations | 0% - 2.6% | x | x | x | ||||||||||||||||||
Hypermagnesaemia | 1% - 2% | 0.5% - 2% | x | x | x | x | x | x | x | x | ||||||||||||
Asthenia | postmarketing — 1% - 6.1% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Eye pain | 0% - 2% | x | x | x | ||||||||||||||||||
Hypoaesthesia | uncommon, 2.2% - 5.6% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Leukopenia | uncommon | x | x | x | x | |||||||||||||||||
Paraesthesia | uncommon — 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Pruritus | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Sleep disturbance | uncommon | x | x | x | ||||||||||||||||||
Stomatitis | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Swelling | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Syncope | uncommon | x | x | x | x | x | ||||||||||||||||
Thrombocytopenia | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Injection site reaction | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Rash macular | uncommon | x | x | x | x | |||||||||||||||||
Induration | uncommon | x | x | x | x | |||||||||||||||||
Redness | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Somnolence | uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Hypocalcaemia | very rare — 1% - 3% | 0.2% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypomagnesaemia | uncommon, 1% - 9% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Acute phase reaction | postmarketing — 0% - 3.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Anaphylactic shock | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Angioedema | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Arthritis | postmarketing — 2.2% - 4% | 1.5% | x | x | x | x | x | x | x | x | x | |||||||||||
Coagulopathy | postmarketing | x | x | x | x | x | ||||||||||||||||
Bronchospasm | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Neoplasm malignant | postmarketing, 14% - 21% | x | x | x | x | x | x | x | x | |||||||||||||
Conjunctivitis | postmarketing, common | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dehydration | postmarketing, 0.6% - 2.5% | 0.6% - 2.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Dysgeusia | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Oedema | postmarketing | x | x | |||||||||||||||||||
Episcleritis | very rare, postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Femur fracture | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Haematuria | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hyperaesthesia | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hyperkalaemia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hypernatraemia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Hypersensitivity | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Inflammation | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Iridocyclitis | postmarketing | x | x | |||||||||||||||||||
Iritis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Renal failure acute | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Oral disorder | postmarketing | x | x | x | ||||||||||||||||||
Plasma cell myeloma | postmarketing, 3.2% | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Cramp muscle | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Musculoskeletal pain | postmarketing — 0.4% - 12.4% | 0.3% - 7.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Osteonecrosis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Pancytopenia | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Proteinuria | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Scleritis | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Shock | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Tremor | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Urticaria | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | ||||||||||||
Uveitis | very rare — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Weight increased | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Dry mouth | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Bronchoconstriction | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Chills | postmarketing, 1.5% - 18.2% | 0.5% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Joint swelling | postmarketing — 0.6% - 3% | 0% | x | x | x | x | x | x | x | x | x | |||||||||||
Interstitial lung disease | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Fatal outcomes | postmarketing | x | ||||||||||||||||||||
Malaise | postmarketing — 0.7% - 7.2% | 0.5% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Vision blurred | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Exacerbation of asthma | postmarketing | x | x | |||||||||||||||||||
Influenza-like symptoms | postmarketing, 6.7% - 8% | x | x | x | x | x | ||||||||||||||||
Orbital oedema | postmarketing | x | x | x | x | x | x | x | ||||||||||||||
Bradycardia | rare | x | x | x | x | |||||||||||||||||
Influenza like illness | postmarketing, 0.8% - 11% | 0.4% - 2.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Sweating increased | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Osteonecrosis of jaw | postmarketing, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Advanced breast cancer | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Arrhythmia | very rare | x | x | x | ||||||||||||||||||
Numbness | very rare | x | x | x | ||||||||||||||||||
Convulsion | very rare | x | x | x | ||||||||||||||||||
Tetany | very rare | x | x | x | ||||||||||||||||||
Agranulocytosis | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Alopecia | x | x | x | x | x | x | x | x | x | |||||||||||||
Atrial flutter | x | |||||||||||||||||||||
Mental disorder | x | x | x | x | x | x | ||||||||||||||||
Bone disorder | x | x | x | x | x | |||||||||||||||||
Connective tissue disorder | x | x | x | x | x | x | x | |||||||||||||||
Dysphagia | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Depression | x | x | x | x | x | x | x | x | ||||||||||||||
Dermatitis | x | x | x | x | x | x | x | x | x | |||||||||||||
Endophthalmitis | x | |||||||||||||||||||||
Eye disorder | x | x | x | x | x | x | x | |||||||||||||||
Gastritis | x | x | ||||||||||||||||||||
Gastrooesophageal reflux disease | x | x | ||||||||||||||||||||
Gastrointestinal disorder | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Cardiac disorder | x | x | x | x | x | x | x | x | ||||||||||||||
Hypogonadism | x | |||||||||||||||||||||
Immune system disorder | x | x | x | x | x | x | ||||||||||||||||
Insomnia NEC | ||||||||||||||||||||||
Renal failure chronic | x | |||||||||||||||||||||
Mediastinal disorder | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Musculoskeletal disorder | ||||||||||||||||||||||
Necrosis ischaemic | x | |||||||||||||||||||||
Metastasis | x | x | ||||||||||||||||||||
Nervous system disorder | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Neutropenia | x | x | x | x | x | x | x | x | ||||||||||||||
Night sweats | ||||||||||||||||||||||
Osteomyelitis | x | x | x | x | x | |||||||||||||||||
Osteopenia | x | |||||||||||||||||||||
Pleural effusion | x | x | ||||||||||||||||||||
Renal failure | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Toothache | x | x | ||||||||||||||||||||
Erythema | x | x | ||||||||||||||||||||
Upper respiratory tract infection | x | x | x | x | x | x | x | x | x | |||||||||||||
Pollakiuria | x | x | ||||||||||||||||||||
Urinary tract disorder | x | x | x | x | x | x | x | |||||||||||||||
Angiopathy | x | x | x | x | x | |||||||||||||||||
Weight decreased | x | x | x | x | x | x | x | x | x | |||||||||||||
Spinal fracture | ||||||||||||||||||||||
Cataract | x | |||||||||||||||||||||
Electrolyte abnormality | x | x | ||||||||||||||||||||
Muscular weakness | x | x | ||||||||||||||||||||
Ocular hyperaemia | x | x | ||||||||||||||||||||
Malnutrition | x | x | x | x | x | x | ||||||||||||||||
Unspecified disorder of skin and subcutaneous tissue | x | x | x | x | x | x | x | x | x | |||||||||||||
Cardiac fibrillation | x | |||||||||||||||||||||
Decreased appetite | x | x | x | x | x | x | x | x | x | x | x | |||||||||||
Abdominal pain lower | x | |||||||||||||||||||||
Leg edema | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Creatinine low | x | |||||||||||||||||||||
Edema of lower extremities | x | x | x | x | x | x | x | x | x | |||||||||||||
Throat sore | x | x | x | x | x | x | x | x | ||||||||||||||
Azotaemia | x | |||||||||||||||||||||
Mucosal inflammation | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Anxiety depression | x | |||||||||||||||||||||
Serum creatinine abnormal | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Reaction gastrointestinal | x | x | x | |||||||||||||||||||
Nephropathy toxic | x | x | x | x | x | x | x | x | x | |||||||||||||
Renal cancer | x | x | x | x | x | x | x | x | ||||||||||||||
Infestation NOS | x | x | x | x | x | x | ||||||||||||||||
Blood and lymphatic system disorders | x | x | x | x | x | x | ||||||||||||||||
Ear and labyrinth disorders | x | x | x | x | ||||||||||||||||||
Sleep disorder | x | |||||||||||||||||||||
Paraesthesia NEC | ||||||||||||||||||||||
Anxiety NEC | ||||||||||||||||||||||
Local reaction | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Infusion related reaction | ||||||||||||||||||||||
Infusion site reaction | x | x | ||||||||||||||||||||
Bone mass decreased | x | |||||||||||||||||||||
Atypical femur fracture | x | x | x | x | ||||||||||||||||||
Blood calcium decreased | x | x |
Information about indications was extracted from the indications and usage sections of the labels.
Indication | Labels | |||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Anaemia | x | |||||||||||||||||||||
Asthma | x | |||||||||||||||||||||
Asthma aspirin-sensitive | x | |||||||||||||||||||||
Atrial fibrillation | x | |||||||||||||||||||||
Bone cancer metastatic | x | x | x | x | x | x | x | x | x | |||||||||||||
Cardiac failure | x | x | ||||||||||||||||||||
Fracture | x | x | ||||||||||||||||||||
Hip fracture | x | x | x | |||||||||||||||||||
Hydraemia | x | x | ||||||||||||||||||||
Hypercalcaemia | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Hypercalcaemia of malignancy | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Hyperparathyroidism | x | x | x | x | x | x | x | x | x | x | ||||||||||||
Hypovolaemia | x | x | ||||||||||||||||||||
Menopause | x | x | ||||||||||||||||||||
Neoplasm | x | x | x | x | x | x | x | |||||||||||||||
Neoplasm malignant | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Osteitis deformans | x | x | x | x | x | x | ||||||||||||||||
Osteoporosis | x | x | x | x | ||||||||||||||||||
Osteoporosis postmenopausal | x | x | x | x | x | x | x | |||||||||||||||
Plasma cell myeloma | x | x | x | x | x | x | x | x | x | |||||||||||||
Prostate cancer | x | x | x | x | x | x | x | x | x | |||||||||||||
Serum creatinine increased | x | |||||||||||||||||||||
Solid tumour | x | x | x | x | x | x | x | x | x | |||||||||||||
Spinal cord compression | x | |||||||||||||||||||||
Spinal fracture | x | |||||||||||||||||||||
Trauma | x | |||||||||||||||||||||
Urine output | x | x |
standard – alternative
100% | ||
75% | ||
50% | ||
10% | ||
frequent (1% to 100%) | ||
infrequent (0.1% to 1%) | ||
rare (<0.1%) | ||
postmarketing | ||
0% | ||
no frequency information | ||
not found on label |