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More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N02CC05

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2
Somnolence frequent, 1% - 5% 2% x x
Dizziness frequent, 3% - 4% 2% x x
Headache frequent, 1% - 2% 1% x x
Nausea 1% - 3% 0% - 1% x x
Paraesthesia 1% 0.5% - 1% x x
Dry mouth 1% 0.5% x x
Abdominal cramps infrequent x x
Anxiety infrequent x x
Asthenia infrequent x x
Back pain infrequent x x
Bronchitis infrequent x x
Neck pain infrequent x x
Chest pain infrequent x x
Diarrhoea infrequent x x
Dysmenorrhoea infrequent x x
Dyspepsia infrequent x x
Dyspnoea infrequent x x
Ear pain infrequent x x
Rash infrequent x x
Fatigue infrequent x x
Gastroenteritis infrequent x x
Hyperglycaemia infrequent x x
Laryngospasm infrequent x x
Pain infrequent x x
Palpitations infrequent x x
Pharyngitis infrequent x x
Pruritus infrequent x x
Rhinitis infrequent x x
Sinusitis infrequent x x
Tinnitus infrequent x x
Tremor infrequent x x
Vasodilation infrequent x x
Vomiting infrequent, 0% - 2% 1% x x
Chills infrequent x x
Increased thirst infrequent x x
Shakiness infrequent x x
Sweating increased infrequent x x
Hypoaesthesia postmarketing, infrequent x x
Tachycardia postmarketing, infrequent x x
Vertigo postmarketing, infrequent x x
Agitation postmarketing, infrequent x x
Myalgia postmarketing, infrequent x x
Abdominal pain postmarketing x x
Anaphylactic shock postmarketing x x
Angina pectoris postmarketing x x
Angioedema postmarketing x x
Arthralgia postmarketing, rare x x
Arthritis rare x x
Mental disorder postmarketing x x
Blepharospasm postmarketing x x
Bone disorder postmarketing x x
Breast disorder postmarketing x x
Colitis postmarketing, rare x x
Confusional state postmarketing x x
Conjunctivitis rare x x
Arteriospasm coronary postmarketing x x
Dermatitis rare x x
Diplopia rare x x
Dysgeusia rare x x
Epistaxis rare x x
Eye disorder postmarketing x x
Body temperature increased rare x x
Gastritis rare x x
Gastrooesophageal reflux disease rare x x
Gastrointestinal disorder postmarketing x x
Cardiac disorder postmarketing x x
Hemiplegia postmarketing x x
Hypercholesterolaemia rare x x
Hyperhidrosis postmarketing x x
Hypersensitivity postmarketing x
Hypertension rare x x
Hyperventilation rare x x
Immune system disorder postmarketing x x
Laryngitis rare x x
Breast pain postmarketing x x
Hypertonia rare x x
Myopathy rare x x
Nervous system disorder postmarketing x x
Nervousness rare x x
Nightmare rare x x
Nystagmus rare x x
Otitis media rare x x
Pain in extremity postmarketing x x
Hyperacusis rare x x
Scotoma rare x x
Convulsion postmarketing x x
Salivary hypersecretion rare x x
Sneezing rare x x
Syncope rare x x
Erythema postmarketing, rare x x
Depressive symptom rare x x
Muscular weakness rare x x
Eye pain rare x x
Hyperreflexia rare x x
Acute myocardial infarction postmarketing x x
Photosensitivity reaction rare x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x
Malaise postmarketing x x
Cold sweat postmarketing x x
Abdominal discomfort postmarketing x x
Abdominal pain upper postmarketing x x
Euphoric mood rare x x
Cerebration impaired rare x x
Eye irritation rare x x
Swollen tongue postmarketing x x
Peripheral coldness postmarketing x x
Dry eye rare x x
Vision blurred postmarketing x
Neuropathy rare x x
Coordination abnormal rare x x
Hypoaesthesia oral postmarketing x x
Ear and labyrinth disorders postmarketing x x
Insomnia rare x x
Parosmia rare x x
Visual impairment postmarketing x
Ischaemia x x
Myocardial infarction x x
Ventricular fibrillation x x
Ventricular tachycardia x x
Vasospasm x x
Myocardial ischaemia x x
Colitis ischaemic x x
Serotonin syndrome x x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:120
Source:FDA Structured Product Label


Side effects:123
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label