More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia
ATC Code: N06AB08
Options: Show MedDRA Preferred Terms, display all 24 labels
Side effect | Data for drug | Placebo | Labels | |||||||||||||||||||
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1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | |||
Insomnia | common — 4% - 35% | 1% - 20% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Asthenia | common — 2% - 28.8% | 1% - 10% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Dry mouth | common — 1% - 25.7% | 1% - 23.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Nervousness | common — 1% - 15.6% | 1% - 9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Diarrhoea | common — 1% - 18% | 0% - 8.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dizziness | common — 2% - 15% | 0% - 13.5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Nausea | frequent, 6% - 40% | 0% - 14% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Somnolence | common — 4% - 27% | 0% - 11% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Constipation | common — 1% - 18% | 1% - 8.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Dyspepsia | common — 1% - 13.8% | 0% - 9.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Upper respiratory tract infection | 9% | 5% | x | x | x | x | x | x | ||||||||||||||
Abnormal ejaculation | infrequent, 0% - 11% | 0% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Sweating | common, 1% - 7% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Anorexia | common — 1% - 14.9% | 0% - 6.3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Pharyngitis | infrequent, 1% - 6.3% | 1% - 5% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Sweating increased | frequent, 6.9% - 11.2% | 1.9% - 12.5% | x | x | x | x | x | x | ||||||||||||||
Infection | infrequent, 11.3% | 9.4% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Pain | infrequent, 4.4% - 10% | 1.3% - 8% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Abdominal pain | common — 1% - 5.6% | 0% - 8.1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Amnesia | infrequent, frequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Anxiety | common — 1% - 9.4% | 1% - 6.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Oedema | rare, frequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Headache | common — 2% - 35% | 1% - 31% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hypotension | infrequent — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Myoclonus | rare, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Syncope | infrequent, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Tremor | common — 0% - 10.8% | 0% - 4.7% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Vomiting | frequent, 2% - 6% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Weight increased | postmarketing, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Weight decreased | postmarketing — 1% - 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypokinesia | infrequent — 8.1% | 3.6% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Accidental injury | infrequent — 3% - 5% | 3% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Manic psychosis | infrequent, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Malaise | infrequent — frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Hyperkinesia | infrequent — 6.7% | 8.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Flatulence | infrequent, 4% | 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Amblyopia | infrequent, 1% - 3% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Dysgeusia | postmarketing, 1% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Influenza | infrequent, 3% - 5% | 2% - 3.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Palpitations | common — 3% | 1% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Tooth disorder | rare, 1% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Pollakiuria | infrequent, 2.2% - 5% | 1.3% - 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Apathy | infrequent — 0% - 3% | 0% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Thinking abnormal | frequent, 1% - 6.9% | 1% - 3.8% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Sinusitis | rare, frequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Cough increased | rare, frequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Libido decreased | infrequent, 2% - 7.5% | 1% - 4% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Dysphagia | postmarketing — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Depression | 1% - 6.3% | 0% - 4.4% | x | x | x | x | x | x | x | |||||||||||||
Dyspnoea | infrequent, 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Hypertension | infrequent — 1% - 2% | 1% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Hypertonia | infrequent, 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Viral infection | 1% - 2% | 1% | x | x | x | |||||||||||||||||
Yawning | rare, 0% - 5% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Chills | rare — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Agitation | common — 1% - 15.7% | 0% - 8.9% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Anorgasmia | postmarketing — 0% - 5% | 0% - 1% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Erectile dysfunction | postmarketing — 2% | 1% - 3% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Sexual dysfunction | 1% - 3% | 1% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Chest pain | infrequent, 3% | 1% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Rhinitis | infrequent, 1.3% - 5.6% | 1.9% - 2.6% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Myalgia | infrequent — 2% - 5% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |
Liver function test abnormal | rare, 2% | 1% | x | x | x | x | x | x | x | x | x | |||||||||||
Urinary retention | postmarketing — 1% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Agoraphobia | infrequent | x | x | x | x | |||||||||||||||||
Alopecia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Anaemia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Angina pectoris | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Anuria | infrequent | x | x | x | x | x | ||||||||||||||||
Arthralgia | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Arthritis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Ataxia | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Back pain | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Bronchitis | rare — 2% | 1% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Bursitis | infrequent | x | x | x | x | |||||||||||||||||
Cardiovascular disorder | infrequent | x | x | x | x | |||||||||||||||||
Neck pain | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Colitis | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Confusional state | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Conjunctivitis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Cystitis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Dehydration | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Delirium | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Delusion | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Depersonalisation | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Dermatitis exfoliative | infrequent | x | x | x | x | x | ||||||||||||||||
Diplopia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Dyskinesia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Dysuria | infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Ecchymosis | postmarketing — 2% - 4% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Eczema | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Epistaxis | rare — 0% - 2% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Eructation | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Oesophagitis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Rash | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Extrapyramidal disorder | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Furunculosis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Gastritis | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Gastroenteritis | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Gastrointestinal haemorrhage | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Gingivitis | rare — 0% - 2% | 0% | x | x | x | x | x | x | x | x | x | x | ||||||||||
Glossitis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hallucination | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Cardiac failure | infrequent | x | x | |||||||||||||||||||
Haematuria | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hemiplegia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Haemorrhoids | infrequent | x | x | x | x | |||||||||||||||||
Hoarseness | infrequent | x | x | x | x | |||||||||||||||||
Hostility | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hypercholesterolaemia | infrequent | x | x | x | x | |||||||||||||||||
Hypersensitivity | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hypoaesthesia | infrequent | x | x | x | x | x | x | |||||||||||||||
Hypochondriasis | infrequent | x | x | x | x | |||||||||||||||||
Orthostatic hypotension | infrequent | x | x | x | x | x | x | x | ||||||||||||||
Hypothyroidism | infrequent | x | x | x | x | |||||||||||||||||
Hysteria | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Libido increased | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Leukocytosis | infrequent | x | x | x | x | |||||||||||||||||
Breast pain | rare, infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Melaena | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Menopause | infrequent | x | x | |||||||||||||||||||
Menorrhagia | postmarketing — 0% - 3% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x |
Hypotonia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Mydriasis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Myocardial infarction | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Neurosis | infrequent, 1% - 2% | 1% | x | x | x | x | x | x | x | x | x | |||||||||||
Nocturia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Otitis media | infrequent | x | x | x | x | |||||||||||||||||
Pallor | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Polyuria | rare — 1% - 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Premenstrual syndrome | infrequent | x | x | |||||||||||||||||||
Pruritus | infrequent, uncommon | x | x | x | x | x | x | x | x | x | x | |||||||||||
Psychotic disorder | rare — frequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hyperacusis | infrequent | x | x | x | x | x | x | |||||||||||||||
Scotoma | infrequent | x | x | x | x | |||||||||||||||||
Seborrhoeic dermatitis | infrequent | x | x | x | x | x | ||||||||||||||||
Convulsion | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Salivary hypersecretion | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Muscle spasms | infrequent | x | x | x | x | |||||||||||||||||
Stomatitis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Suicide attempt | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Tachycardia | postmarketing — frequent | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Tenosynovitis | infrequent | x | x | |||||||||||||||||||
Tetany | infrequent | x | x | x | x | x | x | |||||||||||||||
Thirst | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Thrombocytopenia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Urinary incontinence | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Urinary tract infection | rare — 2% | 1% | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Urticaria | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Vertigo | infrequent, frequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Micturition urgency | rare, infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Stupor | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Mood swings | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Photophobia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Oedema peripheral | infrequent | x | x | x | x | x | x | |||||||||||||||
Migraine | infrequent | x | x | x | x | x | x | x | ||||||||||||||
Neck stiffness | rare, infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
CNS depression NOS | infrequent | x | x | x | x | |||||||||||||||||
Eye pain | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Paranoid reaction | rare, infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Skin discolouration | infrequent | x | x | x | x | x | ||||||||||||||||
Dry skin | rare, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Accommodation disorder | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Tendinous contracture | infrequent | x | x | |||||||||||||||||||
Photosensitivity reaction | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Urination impaired | infrequent | x | x | x | x | x | ||||||||||||||||
Muscle twitching | infrequent, 0% - 2% | 0% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||
Unsteady gait | infrequent | x | x | x | x | |||||||||||||||||
Increased appetite | infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Extrapyramidal symptoms | uncommon | x | x | |||||||||||||||||||
Abnormal dreams | infrequent, 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Euphoric mood | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Suicidal tendency | infrequent | x | x | |||||||||||||||||||
Gastrointestinal ulcer | infrequent | x | x | x | x | |||||||||||||||||
Menstruation delayed | infrequent | x | x | |||||||||||||||||||
Rectal haemorrhage | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Psychotic depression | infrequent | x | x | x | x | x | x | |||||||||||||||
Peripheral coldness | infrequent | x | x | x | x | |||||||||||||||||
Dry eye | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Phobia | infrequent | x | x | x | ||||||||||||||||||
Akathisia | infrequent | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Pulse irregular | infrequent | x | x | x | x | |||||||||||||||||
Bradycardia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Electrocardiogram ST segment | infrequent | x | x | x | x | |||||||||||||||||
Lymphadenopathy | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Coordination abnormal | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Paralysis | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Sleep disorder | infrequent | x | x | x | x | |||||||||||||||||
Cardiomyopathy | infrequent | x | x | x | x | |||||||||||||||||
Hypersomnia | infrequent | x | x | x | x | |||||||||||||||||
Myasthenia | infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Parosmia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Ageusia | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Vaginal haemorrhage | infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Abnormal vision | infrequent | x | x | x | x | x | x | |||||||||||||||
Asthma | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Deafness | rare, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Ear pain | rare, infrequent | x | x | x | x | x | x | x | x | x | ||||||||||||
Hyperventilation | rare, infrequent | x | x | x | x | x | x | x | x | x | x | |||||||||||
Arthropathy | rare, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Metrorrhagia | postmarketing, infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Neuralgia | rare, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Paraesthesia | postmarketing — 3% | 2% | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Gait disturbance | postmarketing, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Aggression | postmarketing | x | x | |||||||||||||||||||
Agranulocytosis | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Amenorrhoea | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||
Anaphylactic shock | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Aplastic anaemia | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Anger | postmarketing | x | x | |||||||||||||||||||
Angioedema | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Apnoea | rare | x | x | x | x | |||||||||||||||||
Arrhythmia | postmarketing, rare | x | x | x | x | x | x | x | x | |||||||||||||
Rheumatoid arthritis | rare | x | x | x | x | x | x | |||||||||||||||
Atrioventricular block | rare | x | x | x | x | |||||||||||||||||
Blepharitis | rare | x | x | x | x | x | x | |||||||||||||||
Breast disorder | postmarketing | x | x | x | ||||||||||||||||||
Bruxism | postmarketing | x | x | |||||||||||||||||||
Cholecystitis | rare | x | x | x | x | |||||||||||||||||
Cholelithiasis | rare | x | x | x | x | |||||||||||||||||
Coma | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Ulcerative keratitis | rare | x | x | x | x | |||||||||||||||||
Cyanosis | rare | x | x | x | x | x | x | |||||||||||||||
Sudden death | rare | x | x | x | x | |||||||||||||||||
Diabetes mellitus | rare | x | x | x | x | |||||||||||||||||
Dysarthria | postmarketing, rare | x | x | x | x | x | x | x | x | |||||||||||||
Dysmenorrhoea | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||
Toxic epidermal necrolysis | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Fatigue | postmarketing | x | x | x | x | x | ||||||||||||||||
Faecal incontinence | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Body temperature increased | postmarketing — infrequent | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Gastrooesophageal reflux disease | postmarketing | x | x | |||||||||||||||||||
Glossodynia | postmarketing | x | x | |||||||||||||||||||
Goitre | rare | x | x | x | x | |||||||||||||||||
Breath odour | rare | x | x | x | x | x | x | |||||||||||||||
Cardiac arrest | postmarketing | x | x | |||||||||||||||||||
Haematemesis | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||
Haemoptysis | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Haemorrhage | postmarketing, rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Hepatitis | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Hernia | rare | x | x | x | x | x | x | |||||||||||||||
Herpes simplex | rare | x | x | x | x | x | x | x | x | |||||||||||||
Herpes zoster | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Hiccups | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Hyperaesthesia | rare | x | x | x | x | x | x | |||||||||||||||
Hyperglycaemia | rare | x | x | x | x | |||||||||||||||||
Hyperlipidaemia | rare | x | x | x | x | |||||||||||||||||
Hyperprolactinaemia | postmarketing | x | x | x | ||||||||||||||||||
Hypoglycaemia | rare | x | x | x | x | x | ||||||||||||||||
Hypokalaemia | rare | x | x | x | x | |||||||||||||||||
Hypomenorrhoea | postmarketing | x | x | x | ||||||||||||||||||
Hyponatraemia | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | |||||||||
Inappropriate antidiuretic hormone secretion | postmarketing | x | x | x | x | x | x | x | x | x | ||||||||||||
Intestinal obstruction | rare | x | x | x | x | |||||||||||||||||
Irritability | postmarketing | x | x | |||||||||||||||||||
Jaundice | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Calculus of kidney | rare | x | x | x | x | |||||||||||||||||
Renal failure acute | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Lacrimal disorder | rare | x | x | x | x | x | x | |||||||||||||||
Laryngospasm | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||
Laryngitis | rare, 0% - 3% | 0% | x | x | x | x | x | x | x | x | x | |||||||||||
Cramps of lower extremities | rare | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Lethargy | postmarketing | x | x | |||||||||||||||||||
Leukopenia | rare | x | x | x | x | |||||||||||||||||
Leukorrhea | rare | x | x | x | x | x | x | |||||||||||||||
Menstrual disorder | postmarketing | x | x | x | ||||||||||||||||||
Myopathy | rare | x | x | x | x | |||||||||||||||||
Mutism | rare | x | x | x | x | |||||||||||||||||
Obesity | rare | x | x | x | x | x | x | |||||||||||||||
Oliguria | rare | x | x | x | x | x | ||||||||||||||||
Pancreatitis | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Pelvic pain | rare | x | x | x | x | x | x | x | ||||||||||||||
Pericarditis | rare | x | x | x | x | |||||||||||||||||
Phlebitis | rare | x | x | x | x | |||||||||||||||||
Pneumonia | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Porphyrin metabolism disorder | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Supraventricular extrasystoles | rare | x | x | x | x | |||||||||||||||||
Priapism | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Prostatic disorder | rare | x | x | x | x | x | x | |||||||||||||||
Psoriasis | rare | x | x | x | x | x | x | |||||||||||||||
Pulmonary infarction | rare | x | x | x | x | |||||||||||||||||
Purpura | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | x | x | x | |||||||
Henoch-Schonlein purpura | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Retinal detachment | rare | x | x | |||||||||||||||||||
Rhabdomyolysis | postmarketing | x | x | |||||||||||||||||||
Shock | postmarketing, rare | x | x | x | x | x | x | x | x | |||||||||||||
Stevens-Johnson syndrome | postmarketing | x | x | x | x | x | x | x | x | x | x | x | x | x | ||||||||
Cerebrovascular accident | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Withdrawal syndrome | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Torsade de pointes | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Torticollis | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Trismus | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Loss of consciousness | postmarketing | x | x | |||||||||||||||||||
Vaginal inflammation | rare, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Vasculitis | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Ventricular tachycardia | postmarketing | x | x | x | x | x | x | x | x | x | x | |||||||||||
Peripheral vascular disorder | rare | x | x | x | x | x | x | |||||||||||||||
Central nervous system neoplasm | rare | x | x | x | x | x | x | |||||||||||||||
Self injurious behaviour | postmarketing | x | x | |||||||||||||||||||
Akinesia | postmarketing, rare | x | x | x | x | x | x | x | x | x | x | x | ||||||||||
Haematospermia | rare | x | x | x | x | x | x | x | ||||||||||||||
Mouth ulceration | rare | x | x | x | x | x | x | |||||||||||||||
Alcohol intolerance | rare | x | x | x | x | x | x | |||||||||||||||
Gastrointestinal carcinoma | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Tongue discolouration | rare | x | x | x | x | x | x | |||||||||||||||
Tongue oedema | rare | x | x | x | x | x | x | |||||||||||||||
Lactation female | rare, infrequent | x | x | x | x | x | x | x | x | |||||||||||||
Lactic dehydrogenase activity increased | rare | x | x | x | x | |||||||||||||||||
Muscular weakness | postmarketing | x | x | |||||||||||||||||||
Biliary colic | rare | x | x | x | x | x | x | x | x | x | x | |||||||||||
Bone pain | rare | x | x | x | x | x | x | |||||||||||||||
Electrocardiogram QT prolonged | postmarketing | x | x | |||||||||||||||||||
Hyporeflexia | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Schizophrenic reaction | rare | x | x | x | x | x | ||||||||||||||||
Syndrome screaming | rare | x | x | x | x | x | ||||||||||||||||
Interstitial lung disease | postmarketing | x | x | |||||||||||||||||||
Hangover | rare | x | x | x | x | x | x | |||||||||||||||
Cardiac fibrillation | rare | x | x | x | x | |||||||||||||||||
Rectal tenesmus | rare | x | x | x | x | x | x | |||||||||||||||
Obsessive rumination | rare | x | x | x | ||||||||||||||||||
Slurred speech | rare | x | x | x | x | |||||||||||||||||
Galactorrhoea | rare | x | x | x | x | x | x | x | x | x | ||||||||||||
Somnolence neonatal | postmarketing | x | x | |||||||||||||||||||
Bullous eruption | postmarketing | x | x | x | x | x | x | x | x | |||||||||||||
Parkinsonism | postmarketing | x | x | |||||||||||||||||||
Mania | rare | x | x | x |