Side effects and indications
Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.)
Information about indications was extracted from the indications and usage sections of the labels.
Show MedDRA Preferred Terms
|
Side effect
|
Data for drug
|
Placebo
|
Labels
(show all 11)
|
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
|
Headache def
|
12% - 27%
|
7% - 23%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Akathisia def
|
2% - 25%
|
0% - 5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Somnolence def
|
4% - 23%
|
3% - 4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sedation
|
2% - 21%
|
1% - 4%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Extrapyramidal disorder def
|
0% - 20%
|
0% - 3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Insomnia def
|
2% - 18%
|
4% - 13%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anxiety def
|
4% - 17%
|
1% - 13%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Fatigue def
|
2% - 17%
|
1% - 4%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Nausea def
|
frequent, 8% - 15%
|
3% - 11%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vomiting def
|
frequent, 3% - 14%
|
0% - 7%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Constipation def
|
2% - 11%
|
2% - 7%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dizziness def
|
2% - 10%
|
1% - 7%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Tremor def
|
rare — 4% - 10%
|
0% - 6%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Drooling
|
infrequent, 4% - 9%
|
0%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Dyspepsia def
|
9%
|
7%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Body temperature increased def
|
infrequent — 5% - 9%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vision blurred def
|
1% - 8%
|
0% - 1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Increased appetite
|
infrequent, 2% - 7%
|
3%
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
|
Decreased appetite
|
frequent, 4% - 7%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Infection def
|
infrequent — 4% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nasopharyngitis def
|
3% - 6%
|
2% - 3%
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Respiratory tract infection def
|
frequent, 4% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Salivary hypersecretion def
|
frequent, 4% - 6%
|
0% - 2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Upper respiratory tract infection def
|
4% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Anaemia def
|
rare — frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anorexia def
|
infrequent, frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Asthenia def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Asthma def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Neck pain def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Chest pain def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Confusional state def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Conjunctivitis def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dehydration def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Delusion def
|
frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Diarrhoea def
|
frequent, 5%
|
3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyskinesia def
|
infrequent — 1%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspnoea def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ear pain def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ecchymosis def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oedema def
|
rare — frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hallucination def
|
infrequent, frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hostility def
|
infrequent, frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertension def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypotension def
|
infrequent, frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Incontinence def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Influenza def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Lethargy def
|
infrequent — 2% - 5%
|
0%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Cramp muscle def
|
rare, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Muscle rigidity def
|
rare — frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Musculoskeletal pain def
|
frequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Nervousness def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pain def
|
rare — 3% - 4%
|
2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pelvic pain def
|
rare — frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pneumonia def
|
rare — frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pruritus def
|
postmarketing — frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Salivation def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Schizoaffective disorder def
|
frequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Sinusitis def
|
frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Skin ulcer def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sweating def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tachycardia def
|
infrequent — 2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ulcer def
|
rare — frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urinary incontinence def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Weight decreased def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dry mouth def
|
rare — 1% - 5%
|
0% - 4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mood swings
|
infrequent, frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Oedema peripheral def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Depressive symptom
|
frequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Neck stiffness
|
frequent
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
Cogwheel rigidity
|
infrequent, frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Creatine phosphokinase increased def
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
|
Manic psychosis
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Paranoid reaction
|
frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Schizophrenic reaction
|
frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Dry skin def
|
infrequent, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Euphoric mood def
|
rare, frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Suicidal ideation def
|
frequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Bradycardia def
|
rare — frequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gait disturbance def
|
frequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Markedly reduced dietary intake
|
frequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Paranoia def
|
frequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Arthralgia def
|
infrequent, 1% - 4%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pain in extremity def
|
4%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Toothache def
|
4%
|
3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Stiffness
|
1% - 4%
|
0% - 3%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Abdominal pain def
|
infrequent, 3%
|
2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cough def
|
infrequent, 3%
|
2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastric disorder def
|
3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Weight increased def
|
2% - 3%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myalgia def
|
1% - 3%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Abdominal discomfort
|
3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Abdominal pain upper
|
3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Disturbance in attention
|
infrequent, 1% - 3%
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Discomfort def
|
3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Upset stomach
|
3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Feeling jittery
|
infrequent, 1% - 3%
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Pharyngolaryngeal pain def
|
infrequent, 3%
|
2%
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Dysmenorrhoea def
|
2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rash def
|
rare — 2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Muscle spasms def
|
postmarketing — 2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rhinorrhoea def
|
infrequent, 2%
|
1%
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Abdominal distension def
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Abscess def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Agoraphobia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Agranulocytosis def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Albuminuria def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Alopecia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Amenorrhoea def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Amnesia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypochromic anaemia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Anaemia macrocytic def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Anger def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Angina pectoris def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Arthritis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ataxia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Atrial fibrillation def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Atrioventricular block def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Blepharitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Blepharospasm def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blister def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blood pressure abnormal
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Bruxism def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Bundle branch block def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Bursitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Candidiasis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oral candidiasis def
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Vaginal moniliasis
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Cellulitis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Chest wall pain def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Cholecystitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cholelithiasis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Colitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cyanosis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cystitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cyst def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Deafness def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Libido decreased def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Decubitus ulcer def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dysphagia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Delirium def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dental caries def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Depersonalisation def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Reactive depression def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Dermatitis def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Diabetes mellitus def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dysarthria def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dysgeusia def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Dysuria def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eczema def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Enuresis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eosinophilia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Epistaxis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eructation def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eye haemorrhage def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eye infection def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Facial pain def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Faecal incontinence def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Faecalith def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Flatulence def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Flushing def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Folliculitis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastritis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastroenteritis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastrooesophageal reflux disease def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastrointestinal haemorrhage def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gingivitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gynaecomastia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cardiac arrest def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cardiac failure def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Haematochezia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Haematoma def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Haematuria def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemorrhage def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemorrhoids def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hiccups def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hoarseness def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hyperbilirubinaemia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hypercholesterolaemia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hyperaesthesia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperglycaemia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperhidrosis def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Hyperkalaemia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hyperlipidaemia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperplasia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypersensitivity def
|
postmarketing, infrequent
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hypoaesthesia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypoglycaemia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypokalaemia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyponatraemia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypothyroidism def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Libido increased def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Infarction def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Intestinal obstruction def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ischaemia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Arthropathy def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Calculus of kidney def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Laryngitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Leukocytosis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Leukopenia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Leukorrhea def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Chronic obstructive pulmonary disease def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Breast pain def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Menorrhagia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertonia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypotonia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myopathy def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Fungal infection def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Myocardial infarction def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myoclonus def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nasal congestion def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Neurodermatitis def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Neutropenia def
|
infrequent
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Night sweats def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Nightmare def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Nocturia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Obesity def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Obstruction def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Osteoarthritis def
|
rare, infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Otitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Otitis externa def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Otitis media def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ovarian cyst def
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Pallor def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Palpitations def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Panic reaction def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Panic disorder def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Paraesthesia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Peptic ulcer def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Abscess periodontal def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Phlebitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pneumonia aspiration def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Polyuria def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Premenstrual syndrome def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Prostatitis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pruritus genital
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Psoriasis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Psychotic disorder def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pyelonephritis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hyperacusis def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Renal failure def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Restless legs syndrome def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rhinitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Seborrhoeic dermatitis def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Stomatitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cerebrovascular accident def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Suicide def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Suicide attempt def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Swelling def
|
rare, infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Sinus tachycardia def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
|
|
|
Testicular pain def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Thirst def
|
infrequent, 1%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Thrombocytopenia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Thrombosis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Onychomycosis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tinnitus def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tooth impacted def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Loss of consciousness def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Deficiency anaemia
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Erythema def
|
rare, infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pollakiuria def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Urinary tract infection def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Uterine disorder def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Uterine haemorrhage def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Vaginal inflammation def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vasodilation def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Venous thrombosis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vertigo def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Wheezing def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Urinary retention def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Chills def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Polydipsia def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Micturition urgency def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Akinesia
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Burning sensation def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Stupor def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Apathy def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oculogyric crisis
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Rash pustular def
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hypokinesia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cataract def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Panic attack def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mouth ulceration def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Urosepsis
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Deep vein thrombosis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Migraine def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Blood urea increased
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Creatinine increased def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Swelling face
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tongue oedema
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Myocardial ischaemia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Lactic dehydrogenase activity increased
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Muscular weakness def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bone pain def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Eye pain def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Phosphatase alkaline increased
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Electrocardiogram QT prolonged def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Vesiculobullous rash
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hyperreflexia
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Aspartate aminotransferase increased def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Alanine aminotransferase increased def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Skin discolouration def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Sinus congestion
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Skin irritation def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Joint swelling
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Urinary hesitation
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Lacrimation increased def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Menstruation irregular def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Haemoglobin decreased def
|
rare, infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Iron deficiency anaemia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Photosensitivity reaction def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Scab
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sickness
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Blood urine
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Oral pain def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Vaginal discharge def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Malaise def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Muscle twitching def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Buttock pain def
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Cardiac fibrillation
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Chest tightness
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Cold sweat
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Abdominal pain lower
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Retching def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Disorientation
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Flat affect
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dysphoria
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bradykinesia
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bradypsychic response
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hallucination, auditory
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Hallucination, visual
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
Memory impairment def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Abnormal dreams
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Rash erythematous
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tremor limb
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Feeling cool
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Excitability
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cerebration impaired def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Dry throat
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eye irritation
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eye redness def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Condition aggravated
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hepatic enzyme increased
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Pain in jaw
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Panic disorder with agoraphobia
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Heart rate irregular
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Productive cough def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gingival pain def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Groin pain
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Iron deficiency
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Dermal cyst
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypomania def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pulmonary congestion
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Erectile dysfunction def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Throat sore def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Lymphoid interstitial pneumonia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Rectal haemorrhage def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Acute psychosis
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Walking difficulty
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blood bilirubin increased def
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Dry eye
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Redness def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Extrasystoles def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Photosensitivity def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Enlargement abdomen def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Nephrolithiasis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dystonia def
|
infrequent, 1%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vaginal infection def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eye discharge
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Lacrimation def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Rash maculo-papular def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperkinesia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Electrocardiogram ST segment
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Neuropathy def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Respiratory distress def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Lymphadenopathy def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dementia def
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Genital itching female
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sinus pain def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Face oedema def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Visual disturbance
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Depressed level of consciousness def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Blood pressure fluctuation
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Lip dry
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Balance disorder
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sensation of heaviness
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Blood glucose increased
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Blood glucose decreased
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blood cholesterol increased
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hot flush def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cardio-respiratory arrest def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
|
Stinging
|
infrequent
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Obsessive thoughts
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tardive dyskinesia def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Aspiration
|
rare, infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mobility decreased
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Acne def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperuricaemia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Taste altered
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Haematocrit decreased
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
White blood cell count increased def
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Completed suicide
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Blood alkaline phosphatase increased def
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Electrocardiogram QT corrected interval prolonged def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Mental status changes
|
infrequent
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Urea increased
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Glucose increased
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Potassium low
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tightness in jaw
|
infrequent
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
Hyperkeratosis def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Joint range of motion decreased def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Muscle tightness
|
infrequent
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Cerebral ischaemia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hypersomnia def
|
infrequent, 1%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sluggishness
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Myasthenia def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Abdominal bloating def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Benign prostatic hyperplasia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Glucose decreased
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Weakness def
|
infrequent
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rhinitis allergic def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Abnormal ejaculation
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Prostatic hyperplasia def
|
infrequent
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Vaginal haemorrhage def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Amblyopia def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Anaphylactic shock def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
x
|
x
|
|
|
x
|
|
Angioedema def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Apnoea def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Appendicitis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Rheumatoid arthritis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Asphyxia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Atrial flutter def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eyelid ptosis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Breast feeding def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Carpal tunnel syndrome def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cervicitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Cheilitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Coccydynia
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cognitive disorder def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Muscle contracture def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Joint contracture
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dermatitis exfoliative def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Diplopia def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Duodenal ulcer def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Embolism def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Epididymitis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Grand mal convulsion def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Oesophagitis def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Reflux oesophagitis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cardiac flutter
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gingival bleeding def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Glossodynia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Glossitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Glycosuria def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Goitre def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gout def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cardiomegaly def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cardiac murmur def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Haematemesis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemoptysis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatitis def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatomegaly def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Hernia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Inguinal hernia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypernatraemia def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperparathyroidism def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hyperthyroidism def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertriglyceridaemia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypertrophy def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Intestinal perforation def
|
rare
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
Irritable bowel syndrome def
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Jaundice def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
|
|
Laryngospasm def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Melaena def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oliguria def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Osteopenia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Osteoporosis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pancreatitis def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Periodontitis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Petechiae def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Tuberculin test positive
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Premature ejaculation def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Priapism def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ptosis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Proteinuria def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pulmonary oedema def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pulmonary embolism def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Purpura def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Rhabdomyolysis def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rhonchi def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Rosacea def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Seizures def
|
postmarketing
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
|
|
Shock def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Septic shock def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sleep apnoea syndrome def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sneezing def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastric ulcer def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Syncope def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tendonitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tenosynovitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Thrombophlebitis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tic def
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Costochondritis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Torticollis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Trismus def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Calculus urinary def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Urticaria def
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Varicose vein def
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Syncope vasovagal def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Idiopathic thrombocytopenic purpura def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Photophobia def
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Periorbital oedema def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Buccoglossal syndrome
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Glucose tolerance decreased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Haemorrhage intracranial def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Hyperchlorhydria
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hyporeflexia
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eyelid oedema
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Respiratory arrest
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Rash vesicular
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Nasal dryness
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Abdominal tenderness
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Blunted affect
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Affect lability
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Suspiciousness
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Logorrhoea
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Derealisation def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Anorgasmia def
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Tenderness def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Intention tremor
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Rash scaly
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Oropharyngeal spasm
|
postmarketing
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
|
|
Muscle contractions involuntary
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blood uric acid increased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Galactorrhoea
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Swollen tongue
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Throat tightness
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Glycosylated haemoglobin increased
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
|
Weight fluctuation
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypoxia def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Azotaemia def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Night cramps
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hypoglycemic reaction def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Tonsillar hypertrophy
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Faeces hard
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Ulcer haemorrhage
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastric ulcer haemorrhage
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Exhaustion
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Localized osteoarthritis
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Psychomotor retardation
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Chapped lips
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Red blood cell count decreased
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Transaminases increased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Urolithiasis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Homicidal ideation
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Pharyngeal erythema
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Coordination abnormal
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypoaesthesia oral
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Neck tightness
|
rare
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
Haemoglobin increased def
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
|
Bradyphrenia
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
White blood cells urine positive
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastrointestinal pain def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Neutrophil count increased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
White blood cell count decreased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Thrombocytosis def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Heaviness of head
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Blood lactate dehydrogenase increased
|
rare
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Neutrophil count decreased def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cells in urine
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cognitive deterioration
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eyelid function disorder def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Potassium increased
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Thrombocytopenic purpura def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cardiomyopathy def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dysphemia
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Bronchopneumopathy
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Muscle enzyme increased
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Respiratory failure def
|
rare
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urine output
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Exostosis def
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cardiopulmonary failure
|
rare
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Fear
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Aphasia def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Back pain def
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Breast disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Catatonia def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Transient ischaemic attack def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Connective tissue disorder def
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Convulsion def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Drug eruption def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Diabetic ketoacidosis def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Endocrine disorder def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Epilepsy def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Eye disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Facial paralysis def
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Fasting def
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Formication
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastrointestinal disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Cardiac disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Hemiparesis
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hirsutism def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Hyperinsulinism def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Orthostatic hypotension def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Body temperature decreased def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Immune system disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Inflammation def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Mediastinal disorder def
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Nervous system disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Neuralgia def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Neuroleptic malignant syndrome def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Pharyngitis def
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Sciatica def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Somnambulism def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Speech disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Subarachnoid haemorrhage def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Supraventricular tachycardia def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Urinary tract disorder def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Angiopathy def
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Ventricular tachycardia def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Choreoathetosis
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Photopsia
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Injection site reaction def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Injection site pain
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
Lightheadedness
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Ketoacidosis
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Rash papular
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Elastosis perforans
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Judgement impaired
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Extrapyramidal symptoms
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tongue spasm
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Dizziness exertional
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tongue paralysis
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Protrusion tongue
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Xerosis
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hepatobiliary disease def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
Glucose tolerance impaired def
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Eruption
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Masked facies
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tongue dry
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Movements involuntary def
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Parkinsonian gait
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Energy increased
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Blood pressure increased
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Paraesthesia oral
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Paralysis def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Inflammation localised
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Carbohydrate tolerance decreased
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Sleep talking
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
PRL increased
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Dissecting aortic aneurysm, thoracic
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Infestation NOS
|
|
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
Intentional self-injury
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Electrocardiogram change def
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Abasia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Ischaemic stroke
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Malignant syndrome NOS
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Dysphasia def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Mental disability
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hyperthermia def
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cerebral haemorrhage def
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Feeling hot
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Loss of libido
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Indication
|
Labels
|
|
Adjuvant therapy def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Aggression def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Agitation def
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
|
|
Autism def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Bipolar disorder def
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Bipolar I disorder
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Depressive disorder def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Irritability def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Major depression def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Mania def
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Mental disorder def
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Schizophrenia def
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Temper tantrum
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Tension def
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
|
|
Information
More information: STITCH, PubChem and possibly Wikipedia or Medpedia
ATC Code:
N05AX12
Legend
Color scheme:
standard – alternative
|
100%
|
|
|
|
75%
|
|
|
|
50%
|
|
|
|
10%
|
|
|
|
frequent (1% to 100%)
|
|
|
|
infrequent (0.1% to 1%)
|
|
|
|
rare (<0.1%)
|
|
|
|
postmarketing
|
|
|
|
0%
|
|
|
|
no frequency information
|
|
|
|
not found on label
|
|
|
Labels
Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.
- ARIPIPRAZOLE :
222 side effects
(FDA XML label)
- ARIPIPRAZOLE :
224 side effects
(FDA XML label)
- ARIPIPRAZOLE :
224 side effects
(FDA XML label)
- aripiprazole / Abilify :
314 side effects
(FDA CDER)
- aripiprazole / Abilify :
316 side effects
(FDA MedWatch)
- ARIPIPRAZOLE / ABILIFY :
331 side effects
(Drugs@FDA)
- ARIPIPRAZOLE / ABILIFY :
332 side effects
(Drugs@FDA)
- ARIPIPRAZOLE / ABILIFY :
358 side effects
(Drugs@FDA)
- ARIPIPRAZOLE / ABILIFY :
525 side effects
(Drugs@FDA)
- ARIPIPRAZOLE / ABILIFY :
544 side effects
(Drugs@FDA)
|