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Olanzapine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N05AH03

Side effects

Options: Show MedDRA Preferred Terms,   display all 53 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Somnolence very common, 3% - 39.1% 3% - 16.2% x x x x x x x x x x x x x x x x x x x x
Headache 13% - 18% 6% - 17% x x x x x x x x x x x x x x x
Increased appetite common — 1% - 29% 0% - 9% x x x x x x x x x x x x x x x x x x x
Nervousness 16% 14% x x
Hallucination very common, 0% - 3% 2% x x x x x x
Lethargy very common x x x x x x x x
PRL increased very common, 47.4% x x
Hypersomnia very common x x x x x x x x
Bilirubin total decreased very common, 22.1% x x x x x x x x x x x x x x x x x
Bilirubin total low very common, 22.1% x x x x x x x x x x x x x x x x x
Hostility 15% 14% x x
Weight increased common — 1% - 43.5% 1% - 9% x x x x x x x x x x x x x x x x x x x x
Accidental injury 12% 8% x x x x x x x x x x x x x x x
Parkinsonism 0% - 20% 0% - 15% x x x x x x x x x x x x x x x x x x x
Insomnia postmarketing, 12% - 20% 11% - 19% x x x x x x x x x x x x x x x x x x
Asthenia common, 2% - 27% 1% - 23% x x x x x x x x x x x x x x x x x x
Pain 0% - 10% 0% - 9% x x x
Anxiety postmarketing, 9% 8% x x x x x
Constipation common, 4% - 14.5% 0% - 9% x x x x x x x x x x x x x x x x x x x
Dizziness common, 1% - 18% 2% - 11% x x x x x x x x x x x x x x x x x x x x
Personality disorder 8% 4% - 8% x x x x x x x x x x x x x x x x x
Alanine aminotransferase increased 8% 3% x x x x x x x x x x x x x x x x x
Dyspepsia 3% - 11% 1% - 5% x x x x x x x x x x x x x x x
Rhinitis 7% - 10% 6% x x x x x x x x x x x x x x x
Fatigue common, 1.5% - 14% 2% - 6% x x x x x x x x x x x x x x x x x x
Gamma-glutamyltransferase increased very common, 2% - 10.1% 1% x x
Abdominal pain infrequent, 3% - 6% 2% - 7% x x x x x x x x x x x x x x x x
Dry mouth common, 2% - 22% 0% - 7% x x x x x x x x x x x x x x x x x x x
Cough increased 5% - 6% 3% x x x x x x x x x x x x x x x
Gait disturbance infrequent — 6% 1% x x x x x x x x x x x x x x x x x x
Back pain 3% - 5% 2% - 4% x x x x x x x x x x x x x x x x
Conjunctivitis frequent x x
Cough 3% - 9% 5% x
Delusion frequent x
Dyspnoea frequent x x x x x x x x x x x x x x x x
Ecchymosis 5% 3% x x x x x x x x x x x x x x x
Eosinophilia common x x x
Body temperature increased rare — 0% - 6% 0% - 3% x x x x x x x x x x x x x x x x x x
Flatulence frequent, 1% - 2% 0% x x
Orthostatic hypotension common — 1% - 5% 0% - 5% x x x x x x x x x x x x x x x x x x x x
Influenza frequent x
Pain in extremity 5% - 6% 0% - 3% x x x x x x x x x x x x x x x
Paraesthesia frequent x x x x x x x x x x x x x x x
Pneumonia common x x x x
Salivary hypersecretion frequent x x x x x x x x x x x x x x x
Thirst frequent x x x x x x x x x x x x x x
Toothache frequent, 3% - 4% 0% x x
Vaginal inflammation frequent x x x x x x x x x x x x x x x
Mood swings infrequent, frequent x x
Manic psychosis frequent x
Injection site pain frequent, 2% - 3% 0% x x x
Schizophrenic reaction frequent x x
Joint stiffness frequent x
Akathisia infrequent, 0% - 27% 0% - 23% x x x x x x x x x x x x x x x x x x x x
Nasopharyngitis 1% - 6% 2% x x x x x x x x x x x x x
Pharyngitis 1.6% - 10.1% 1.5% - 3% x x x x x x x x x x x x x x x
Speech disorder 4% 1% x x x x x x x x x x x x x x x x x x
Tremor postmarketing, 0% - 7% 0% - 3% x x x x x x x x x x x x x x x x x x x x
Vaginal discharge 0% - 4% 0% x
Amblyopia 3% - 5% 2% - 4% x x x x x x x x x x x x x x x
Arthralgia uncommon — 2% - 5% 0% - 3% x x x x x x x x x x x x x x x
Chest pain 3% - 4% 1% - 2% x x x x x x x x x x x x x x x
Diarrhoea infrequent, 2% - 7% 0% - 4% x x x x x x x x x x x x x x x
Hypertonia 3% - 4% 2% - 3% x x x x x x x x x x x x x x x x
Respiratory tract infection 3% 2% x x x x x x x x x x x x x x
Sinusitis 3% 0% x x x x x x x x x x x x
Tachycardia 3% - 4% 1% x x x x x x x x x x x x x x x x x
Upper respiratory tract infection 1% - 4% 2% x x x x
Agitation 1% - 23% 2% - 17% x x x x x x x x x x x
Hepatic enzyme increased 1% - 4% 1% x
Pharyngolaryngeal pain 2% - 3% 2% x
Amnesia uncommon — 2% 0% x x x x x x x x x x x x x x x
Phonological disorder infrequent, 2% 1% x x x x x x x x x x x x x x
Blepharitis infrequent, 2% 1% x x
Fungal skin infection 2% 0% x
Oedema 2% 0% x x x x x x x x x x x x x x x x
Eye disorder 2% 1% x
Hypertension 0% - 3% 0% - 1% x x x x x x x x x x x x x x x x
Hypotension common — 2% 0% - 1% x x x x x
Arthropathy infrequent, 2% 1% x x
Menstrual disorder 2% 0% x
Nasal congestion 1% - 7% 3% x
Muscle spasms 1% - 3% 0% x x x x x x x x x x x x x x
Urinary incontinence very rare — 2% 1% x x x x x x x x x x x x x x x x x x
Urinary tract infection 2% 1% x x x x x x x x x x x x x x
Oedema peripheral common, 1% - 3% 0% - 1% x x x x x x x x x x x x x x x x x x
Neck stiffness infrequent, 2% 1% x x x x x x
Vesiculobullous rash infrequent, 2% 1% x x
Aspartate aminotransferase increased very common, 2% - 27.6% 0% x x x x x x x x x x x x x x x x
Muscle twitching infrequent — 2% 1% x x x x x x
Euphoric mood frequent, 2% 0% x x x x x x x x x x x x x x x
Acne 0% - 2% 0% x x x x x x x x x x x x x x x
Musculoskeletal stiffness 1% - 4% 0% - 1% x x x x x x x x x x x x x
Drug dependence 2% 0% x
Abnormal dreams frequent, 0% - 4.3% 0% x x x
Neurosis 1% 0% x
Corneal lesion rare, 1% 0% x x
Intentional injury infrequent, 1% 0% x x
Abdominal distension uncommon
Acidosis infrequent x
Alopecia very rare — infrequent x x x x x x x x x x x x x x x x x x
Amenorrhoea infrequent x x x x x x x x x
Anaemia infrequent x
Apnoea infrequent x
Arthritis infrequent x
Asthma infrequent x
Ataxia infrequent x x x x x x x x x x x x x x x
Atrial fibrillation infrequent x
Atrioventricular block infrequent
Candida infection infrequent x
Oral candidiasis infrequent x
Neck pain infrequent x
Confusional state infrequent x x x x x x x x x x x x x x x
Cyanosis infrequent x
Cystitis infrequent x
Deafness infrequent x
Libido decreased infrequent x x x x x x x x x x x x x x x x x
Dysphagia infrequent x x x x x x x x x x x x x x x
Dehydration infrequent x
Delirium infrequent x
Dental caries infrequent x x
Depersonalisation infrequent x
Dermatitis contact infrequent x
Diabetes mellitus very rare — infrequent x x x x x
Diplopia infrequent x
Dysarthria infrequent, 0% - 2% 0% x x x x x x x x x x x x x x x
Dysgeusia infrequent x
Dysuria infrequent x
Ear pain infrequent, 1% - 4% 2% x x
Eczema infrequent x
Endophthalmitis infrequent x
Epistaxis infrequent — 3% 0% x x x x x x x x x x x x x x x
Oesophagitis infrequent x
Eye haemorrhage infrequent x
Facial paralysis infrequent x
Faecal incontinence infrequent x
Faecalith infrequent x
Gastritis infrequent x
Gastroenteritis infrequent x
Gingivitis infrequent x
Glycosuria infrequent, common x x x x
Gynaecomastia infrequent x x x x
Cardiac arrest infrequent x x
Block heart infrequent
Cardiac failure congestive infrequent x
Haematuria infrequent x
Haemoptysis infrequent x
Haemorrhage infrequent x
Hyperbilirubinaemia infrequent x x x x x x x x x x x x x x x
Hypercholesterolaemia postmarketing — common x x x x x
Hyperlipidaemia infrequent x x
Hyperventilation infrequent x
Hypoaesthesia infrequent x
Hypoglycaemia infrequent x
Hypokalaemia infrequent x
Hyponatraemia infrequent x
Hypoproteinaemia rare, infrequent x x x x x x x x x x x x x x x
Libido increased infrequent x x
Laryngitis infrequent x
Cramps of lower extremities infrequent x
Leukocytosis infrequent x
Leukopenia postmarketing — 1% 0% x x x x x x x x x x x x x x x x x x x
Breast pain infrequent x x x x x x x x x x x x x x x
Melaena infrequent x
Menorrhagia infrequent x x x x x x x
Metrorrhagia infrequent x x x x x x x
Hypotonia infrequent x
Nausea postmarketing — 0% - 9% 2% - 9% x x x x x x x x x x x x x x x x x x x
Pallor infrequent x
Palpitations infrequent x
Pelvic pain infrequent x
Abscess periodontal infrequent x
Polyuria infrequent x x x x x x x
Premenstrual syndrome infrequent x
Pyuria infrequent x
Seborrhoeic dermatitis infrequent x
Skin ulcer infrequent x
Stomatitis infrequent x
Cerebrovascular accident infrequent x x x x x x x x x x x x x x x
Stuttering infrequent x
Withdrawal syndrome infrequent x
Suicide infrequent x x x x x x x
Suicide attempt infrequent x x x x x x x x
Sweating postmarketing — frequent x x x x x x x x x x x x x x x x x x
Syncope infrequent x x
Thrombocytopenia very rare — infrequent x x x x x x x x x x x x x x x x x x
Tinnitus infrequent x
Pollakiuria infrequent x x x x x x x x x x x x x x x
Vertigo infrequent x
Vomiting postmarketing — 1% - 6% 2% - 3% x x x x x x x x x x x x x x x x x x x x
Urinary retention very rare, infrequent x x x x x x x x x x x x x x x x x
Micturition urgency infrequent x x x x x x x x x x x x x x x
Akinesia infrequent x x x x x x
Stupor infrequent x x x x x x x x x x x x x x x
Hypokinesia infrequent x x x x x x
Cataract infrequent x
Mouth ulceration infrequent x
Migraine infrequent x
Cogwheel rigidity infrequent x x x x x x
Creatine phosphokinase increased very rare — 1% 0% x x x x
Tongue oedema infrequent x x x x x x x x x x x x x x x
Ventricular extrasystoles infrequent x
Lactation female infrequent x
Eye pain infrequent x
Phosphatase alkaline increased very rare — infrequent x x x x x x x x x x x x x x x x x x
Skin discolouration infrequent x
Dry skin infrequent x x x x x x x x x x x x x x
Uterine fibroids enlarged infrequent x
Accommodation disorder infrequent x x x x x x x x x x x x x x x
Photosensitivity reaction infrequent, uncommon x x x x x x x x x x x x x x x x x x x
Malaise infrequent x
Urination impaired infrequent x x x x x x x x x x x x x x x
Antisocial behaviour infrequent x
Edema of lower extremities infrequent x
Erectile dysfunction infrequent x x x x x x x x x
Rectal haemorrhage infrequent x
Dry eye infrequent x x x x x x x x x x x x x x x
Phobia infrequent x
Enlargement abdomen infrequent x
Rash maculo-papular infrequent x x
Bradycardia infrequent, uncommon x x x x x x x
Lymphadenopathy infrequent x
Dementia infrequent x
Coordination abnormal infrequent x x x x x x x x x x x x x x
Upper limb oedema infrequent x
Face oedema infrequent x x x x x x x x x x x x x x x
Tardive dyskinesia infrequent x x x x x x x x x
Hyperuricaemia infrequent x
Myasthenia infrequent x
Abnormal ejaculation infrequent x
Vaginal haemorrhage infrequent x
Chills rare, infrequent x x x x x x x x x x x x x x x
Albuminuria rare x
Angioedema postmarketing x x x x x x x x x x x x x x x x x x
Arteritis rare x
Rheumatoid arthritis rare x
Atelectasis rare x
Bursitis rare x
Coma rare x x x x x x x x x x x x x x x x
Sudden death rare x x x x x x x x x
Diabetic ketoacidosis very rare — rare x x x x x x x x x x x x x x x x x x
Enteritis rare x
Eructation rare x
Rash postmarketing — 2% 1% x x x x x x x x x x x x x x x x x x x
Glaucoma rare x
Glossitis rare x
Goitre rare x
Gout rare x
Cardiac failure rare x
Hepatitis postmarketing — infrequent x x x x x x x x x x x x x x x x x x x
Hiccups rare x
Hirsutism rare x
Hyperglycaemia postmarketing — infrequent x x x x
Hyperkalaemia rare, infrequent x
Hypernatraemia rare x
Hypersensitivity very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Hypertriglyceridaemia postmarketing x x x
Intestinal obstruction rare x x x x x x x x x x x x x x x
Jaundice very rare, postmarketing x x x x x x x x x x x x x x x x
Keratoconjunctivitis rare x
Ketosis rare x
Mastitis rare x
Miosis rare x
Myopathy rare x
Mydriasis rare x x x x x x x x x x x x x x x
Neuralgia rare x
Neutropenia postmarketing — common x x x x x x x x x x x x x x x x x
Nystagmus rare x
Oliguria rare x
Osteoporosis rare x x x x x x x x x x x x x x x
Pancreatitis very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Priapism very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Pruritus postmarketing, infrequent x x x x x x x x x x x x x x x x x x
Pulmonary oedema rare x x x x x x x x x x x x x x x
Pulmonary embolism very rare — rare x x x x x x x x x x x x x x x x x x x
Rhabdomyolysis very rare, postmarketing x x x x x x x x x x x x x x x x x x
Convulsion postmarketing, rare x x x
Aphthous stomatitis rare x
Stridor rare x
Subarachnoid haemorrhage rare x
Urticaria postmarketing, infrequent x x x x x x x x x x x x x x x x x x
Water intoxication rare x
Normocytic anemia rare x
Encephalopathy rare x
Rash pustular rare x
Deep vein thrombosis very rare, postmarketing x x x x x x x x x x x x x x x x x
Tongue discolouration rare x
Lenticular pigmentation rare x
Liver fatty deposition rare x x x x x x x x x x x x x x x
Bone pain rare x
Circumoral paresthesia rare x
Oesophageal ulcer rare x
Urinary hesitation very rare, postmarketing x x x
Leukoderma rare x
Hangover rare x x x x x x x x x x x x x x x
Hepatobiliary disease postmarketing x x x
Anaphylactoid reaction postmarketing x x x x x x x x x x x x x x x x x x
Neuropathy rare x
Paralysis rare x
Sweating increased postmarketing x x x x x x x x x x x x x x x
Thrombocytosis rare x
Thromboembolic event postmarketing x x x x x x x x x x x x x x
Ileus rare x x x x x x x x x x x x x x x
Diabetic coma very rare, postmarketing x x x x x x x x x x x x x x x x x x
Breast enlargement rare x x x x
Hypoventilation rare x
Neuroleptic malignant syndrome very rare, postmarketing x x
Bilirubin total increased very rare, postmarketing x x x
Venous thromboembolism very rare, postmarketing x x x
Dementia Alzheimer's type x x x x x x x x x x x x x x x
Anorexia x x
Mental disorder x
Breast disorder x x
Infection x x x
Connective tissue disorder x x
Depression x x x x x x x x x x x x
Dyskinesia x x x x x x x x x
Dysmenorrhoea x x x x x x x x x x x x x x x
Embolism
Extrapyramidal disorder x x x x x x x x x
Fasting x
Gastrointestinal disorder x x
Cardiac disorder x
Body temperature decreased x
Immune system disorder x
Mediastinal disorder x
Muscle rigidity
Myoclonus x x x x x x
Drug withdrawal syndrome neonatal x
Nervous system disorder x x
Obesity x
Parkinson's disease x x x x
Pregnancy x
Sneezing 0% - 2% 0% x
Thromboembolism x
Torsade de pointes x
Torticollis x x x x x x
Unintended pregnancy x
Erythema x
Urinary tract disorder x
Angiopathy x x
Ventricular tachycardia x
Viral infection 0% - 2% 0% x
Weight decreased x x
Choreoathetosis x x x x x x
Hepatic failure x x x x x x x x x x x x x x
Ventricular arrhythmia x
Apathy x x x x x x x x x x x x x x x
Oculogyric crisis x x x x x x
Lower respiratory tract infection x x x
Buccoglossal syndrome x x x x x x
Injection site reaction x
Injection site mass x
Opisthotonus x x x x x x
Paranoid reaction x x
Generalised spasm x x x x x x
Haemoglobin decreased x
Malnutrition x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x x
Ketoacidosis x
Myalgia x x
Buttock pain x
Cardiac fibrillation x
Abdominal pain upper x x x x x
Abdominal pain lower x x x x x
Psychiatric symptom x x x x x x x x x x x x x x x
Thinking abnormal 0% - 3% 1% x x x
Hallucination, visual x
Galactorrhoea x x x
Tolerance development
Throat tightness x x x x x x