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Olanzapine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N05AH03

Side effects

Options: Show MedDRA Preferred Terms,   display all 53 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Somnolence very common, 3% - 39.1% 3% - 16.2% x x x x x x x x x x x x x x x x x x x x
Headache 13% - 18% 6% - 17% x x x x x x x x x x x x x x x
Increased appetite common — 1% - 29% 0% - 9% x x x x x x x x x x x x x x x x x x x
Nervousness 16% 14% x x x
Hallucination very common, 0% - 3% 2% x x x x x x x
Lethargy very common x x x x x x x
PRL increased very common, 47.4% x
Hypersomnia very common x x x x x x x
Bilirubin total decreased very common, 22.1% x x x x x x x x x x x x x x x x
Bilirubin total low very common, 22.1% x x x x x x x x x x x x x x x x
Hostility 15% 14% x x x
Weight increased common — 1% - 43.5% 1% - 9% x x x x x x x x x x x x x x x x x x x x
Accidental injury 12% 8% x x x x x x x x x x x x x x x
Parkinsonism 0% - 20% 0% - 15% x x x x x x x x x x x x x x x x x x x
Insomnia postmarketing, 12% - 20% 11% - 19% x x x x x x x x x x x x x x x x x x
Asthenia common, 2% - 27% 1% - 23% x x x x x x x x x x x x x x x x x x
Pain 0% - 10% 0% - 9% x x x x
Anxiety postmarketing, 9% 8% x x x x x x
Constipation common, 4% - 14.5% 0% - 9% x x x x x x x x x x x x x x x x x x x
Dizziness common, 1% - 18% 2% - 11% x x x x x x x x x x x x x x x x x x x x
Personality disorder 8% 4% - 8% x x x x x x x x x x x x x x x x x
Alanine aminotransferase increased 8% 3% x x x x x x x x x x x x x x x x x
Dyspepsia 3% - 11% 1% - 5% x x x x x x x x x x x x x x x
Rhinitis 7% - 10% 6% x x x x x x x x x x x x x x x
Fatigue common, 1.5% - 14% 2% - 6% x x x x x x x x x x x x x x x x x
Gamma-glutamyltransferase increased very common, 2% - 10.1% 1% x x x
Abdominal pain infrequent, 3% - 6% 2% - 7% x x x x x x x x x x x x x x x x
Dry mouth common, 2% - 22% 0% - 7% x x x x x x x x x x x x x x x x x x x
Cough increased 5% - 6% 3% x x x x x x x x x x x x x x x
Gait disturbance infrequent — 6% 1% x x x x x x x x x x x x x x x x x x
Back pain 3% - 5% 2% - 4% x x x x x x x x x x x x x x x x
Conjunctivitis frequent x x x
Cough 3% - 9% 5% x
Delusion frequent x x
Dyspnoea frequent x x x x x x x x x x x x x x x x
Ecchymosis 5% 3% x x x x x x x x x x x x x x x
Eosinophilia common x x x
Body temperature increased rare — 0% - 6% 0% - 3% x x x x x x x x x x x x x x x x x x x
Flatulence frequent, 1% - 2% 0% x x x
Orthostatic hypotension common — 1% - 5% 0% - 5% x x x x x x x x x x x x x x x x x x x x
Influenza frequent x x
Pain in extremity 5% - 6% 0% - 3% x x x x x x x x x x x x x x x
Paraesthesia frequent x x x x x x x x x x x x x x x
Pneumonia common x x x x
Salivary hypersecretion frequent x x x x x x x x x x x x x x x
Thirst frequent x x x x x x x x x x x x x x
Toothache frequent, 3% - 4% 0% x x x
Vaginal inflammation frequent x x x x x x x x x x x x x x x
Mood swings infrequent, frequent x x x
Manic psychosis frequent x x
Injection site pain frequent, 2% - 3% 0% x x x x x
Schizophrenic reaction frequent x x x
Joint stiffness frequent x x
Akathisia infrequent, 0% - 27% 0% - 23% x x x x x x x x x x x x x x x x x x x x
Nasopharyngitis 1% - 6% 2% x x x x x x x x x x x x
Pharyngitis 1.6% - 10.1% 1.5% - 3% x x x x x x x x x x x x x x x
Speech disorder 4% 1% x x x x x x x x x x x x x x x x x x
Tremor postmarketing, 0% - 7% 0% - 3% x x x x x x x x x x x x x x x x x x x x
Vaginal discharge 0% - 4% 0% x
Amblyopia 3% - 5% 2% - 4% x x x x x x x x x x x x x x x
Arthralgia uncommon — 2% - 5% 0% - 3% x x x x x x x x x x x x x x x x
Chest pain 3% - 4% 1% - 2% x x x x x x x x x x x x x x x
Diarrhoea infrequent, 2% - 7% 0% - 4% x x x x x x x x x x x x x x x
Hypertonia 3% - 4% 2% - 3% x x x x x x x x x x x x x x x x
Respiratory tract infection 3% 2% x x x x x x x x x x x x x
Sinusitis 3% 0% x x x x x x x x x x x
Tachycardia 3% - 4% 1% x x x x x x x x x x x x x x x x x
Upper respiratory tract infection 1% - 4% 2% x x x
Agitation 1% - 23% 2% - 17% x x x x x x x x x x
Hepatic enzyme increased 1% - 4% 1% x
Pharyngolaryngeal pain 2% - 3% 2% x
Amnesia uncommon — 2% 0% x x x x x x x x x x x x x x x
Phonological disorder infrequent, 2% 1% x x x x x x x x x x x x x x
Blepharitis infrequent, 2% 1% x x x
Fungal skin infection 2% 0% x
Oedema 2% 0% x x x x x x x x x x x x x x x x x
Eye disorder 2% 1% x
Hypertension 0% - 3% 0% - 1% x x x x x x x x x x x x x x x x
Hypotension common — 2% 0% - 1% x x x x x x x
Arthropathy infrequent, 2% 1% x x x
Menstrual disorder 2% 0% x
Nasal congestion 1% - 7% 3% x
Muscle spasms 1% - 3% 0% x x x x x x x x x x x x x
Urinary incontinence very rare — 2% 1% x x x x x x x x x x x x x x x x x x
Urinary tract infection 2% 1% x x x x x x x x x x x x x x
Oedema peripheral common, 1% - 3% 0% - 1% x x x x x x x x x x x x x x x x x
Neck stiffness infrequent, 2% 1% x x x x x x
Vesiculobullous rash infrequent, 2% 1% x x x
Aspartate aminotransferase increased very common, 2% - 27.6% 0% x x x x x x x x x x x x x x
Muscle twitching infrequent — 2% 1% x x x x x x
Euphoric mood frequent, 2% 0% x x x x x x x x x x x x x x x
Acne 0% - 2% 0% x x x x x x x x x x x x x x x
Musculoskeletal stiffness 1% - 4% 0% - 1% x x x x x x x x x x x x
Drug dependence 2% 0% x
Abnormal dreams frequent, 0% - 4.3% 0% x x x x
Neurosis 1% 0% x
Corneal lesion rare, 1% 0% x x x
Intentional injury infrequent, 1% 0% x x x
Abdominal distension uncommon x
Acidosis infrequent x x
Alopecia very rare — infrequent x x x x x x x x x x x x x x x x x x
Amenorrhoea infrequent x x x x x x x x x x
Anaemia infrequent x x
Apnoea infrequent x x
Arthritis infrequent x x
Asthma infrequent x x
Ataxia infrequent x x x x x x x x x x x x x x x
Atrial fibrillation infrequent x x
Atrioventricular block infrequent x
Candida infection infrequent x x
Oral candidiasis infrequent x x
Neck pain infrequent x x
Confusional state infrequent x x x x x x x x x x x x x x x
Cyanosis infrequent x x
Cystitis infrequent x x
Deafness infrequent x x
Libido decreased infrequent x x x x x x x x x x x x x x x x x
Dysphagia infrequent x x x x x x x x x x x x x x x
Dehydration infrequent x x
Delirium infrequent x x
Dental caries infrequent x x x
Depersonalisation infrequent x x
Dermatitis contact infrequent x x
Diabetes mellitus very rare — infrequent x x x x x x
Diplopia infrequent x x
Dysarthria infrequent, 0% - 2% 0% x x x x x x x x x x x x x x x
Dysgeusia infrequent x x
Dysuria infrequent x x
Ear pain infrequent, 1% - 4% 2% x x x
Eczema infrequent x x
Endophthalmitis infrequent x x
Epistaxis infrequent — 3% 0% x x x x x x x x x x x x x x x x
Oesophagitis infrequent x x
Eye haemorrhage infrequent x x
Facial paralysis infrequent x x
Faecal incontinence infrequent x x
Faecalith infrequent x x
Gastritis infrequent x x
Gastroenteritis infrequent x x
Gingivitis infrequent x x
Glycosuria infrequent, common x x x x x
Gynaecomastia infrequent x x x x
Cardiac arrest infrequent x x
Block heart infrequent x
Cardiac failure congestive infrequent x x
Haematuria infrequent x x
Haemoptysis infrequent x x
Haemorrhage infrequent x x
Hyperbilirubinaemia infrequent x x x x x x x x x x x x x x x
Hypercholesterolaemia postmarketing — common x x x x x x
Hyperlipidaemia infrequent x x x
Hyperventilation infrequent x x
Hypoaesthesia infrequent x x
Hypoglycaemia infrequent x x
Hypokalaemia infrequent x x
Hyponatraemia infrequent x x
Hypoproteinaemia rare, infrequent x x x x x x x x x x x x x x x
Libido increased infrequent x x x
Laryngitis infrequent x x
Cramps of lower extremities infrequent x x
Leukocytosis infrequent x x
Leukopenia postmarketing — 1% 0% x x x x x x x x x x x x x x x x x x x
Breast pain infrequent x x x x x x x x x x x x x x x
Melaena infrequent x x
Menorrhagia infrequent x x x x x x x x
Metrorrhagia infrequent x x x x x x x x
Hypotonia infrequent x x
Nausea postmarketing — 0% - 9% 2% - 9% x x x x x x x x x x x x x x x x x x x
Pallor infrequent x x
Palpitations infrequent x x
Pelvic pain infrequent x x
Abscess periodontal infrequent x x
Polyuria infrequent x x x x x x x x
Premenstrual syndrome infrequent x x
Pyuria infrequent x x
Seborrhoeic dermatitis infrequent x x
Skin ulcer infrequent x x
Stomatitis infrequent x x
Cerebrovascular accident infrequent x x x x x x x x x x x x x x x
Stuttering infrequent x x
Withdrawal syndrome infrequent x x
Suicide infrequent x x x x x x
Suicide attempt infrequent x x x x x x x x x
Sweating postmarketing — frequent x x x x x x x x x x x x x x x x x x
Syncope infrequent x x x x
Thrombocytopenia very rare — infrequent x x x x x x x x x x x x x x x x x
Tinnitus infrequent x x
Pollakiuria infrequent x x x x x x x x x x x x x x x
Vertigo infrequent x x
Vomiting postmarketing — 1% - 6% 2% - 3% x x x x x x x x x x x x x x x x x x x x
Urinary retention very rare, infrequent x x x x x x x x x x x x x x x x x
Micturition urgency infrequent x x x x x x x x x x x x x x x
Akinesia infrequent x x x x x x
Stupor infrequent x x x x x x x x x x x x x x x
Hypokinesia infrequent x x x x x x
Cataract infrequent x x
Mouth ulceration infrequent x x
Migraine infrequent x x
Cogwheel rigidity infrequent x x x x x x
Creatine phosphokinase increased very rare — 1% 0% x x x x x
Tongue oedema infrequent x x x x x x x x x x x x x x x
Ventricular extrasystoles infrequent x x
Lactation female infrequent x x
Eye pain infrequent x x
Phosphatase alkaline increased very rare — infrequent x x x x x x x x x x x x x x x x x x
Skin discolouration infrequent x x
Dry skin infrequent x x x x x x x x x x x x x x
Uterine fibroids enlarged infrequent x x
Accommodation disorder infrequent x x x x x x x x x x x x x x x
Photosensitivity reaction infrequent, uncommon x x x x x x x x x x x x x x x x x x x
Malaise infrequent x x
Urination impaired infrequent x x x x x x x x x x x x x x x
Antisocial behaviour infrequent x x
Edema of lower extremities infrequent x x
Erectile dysfunction infrequent x x x x x x x x x x
Rectal haemorrhage infrequent x x
Dry eye infrequent x x x x x x x x x x x x x x x
Phobia infrequent x x
Enlargement abdomen infrequent x x
Rash maculo-papular infrequent x x x
Bradycardia infrequent, uncommon x x x x x x x x x
Lymphadenopathy infrequent x x
Dementia infrequent x x
Coordination abnormal infrequent x x x x x x x x x x x x x x
Upper limb oedema infrequent x x
Face oedema infrequent x x x x x x x x x x x x x x x
Tardive dyskinesia infrequent x x x x x x x x x
Hyperuricaemia infrequent x x
Myasthenia infrequent x x
Abnormal ejaculation infrequent x x
Vaginal haemorrhage infrequent x x
Chills rare, infrequent x x x x x x x x x x x x x x x
Albuminuria rare x x
Angioedema postmarketing x x x x x x x x x x x x x x x x x
Arteritis rare x x
Rheumatoid arthritis rare x x
Atelectasis rare x x
Bursitis rare x x
Coma rare x x x x x x x x x x x x x x x x x
Sudden death rare x x x x x x x x x x x
Diabetic ketoacidosis very rare — rare x x x x x x x x x x x x x x x x x
Enteritis rare x x
Eructation rare x x
Rash postmarketing — 2% 1% x x x x x x x x x x x x x x x x x x x
Glaucoma rare x x
Glossitis rare x x
Goitre rare x x
Gout rare x x
Cardiac failure rare x x
Hepatitis postmarketing — infrequent x x x x x x x x x x x x x x x x x x x
Hiccups rare x x
Hirsutism rare x x
Hyperglycaemia postmarketing — infrequent x x x x
Hyperkalaemia rare, infrequent x x
Hypernatraemia rare x x
Hypersensitivity very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Hypertriglyceridaemia postmarketing x x
Intestinal obstruction rare x x x x x x x x x x x x x x x
Jaundice very rare, postmarketing x x x x x x x x x x x x x x
Keratoconjunctivitis rare x x
Ketosis rare x x
Mastitis rare x x
Miosis rare x x
Myopathy rare x x
Mydriasis rare x x x x x x x x x x x x x x x
Neuralgia rare x x
Neutropenia postmarketing — common x x x x x x x x x x x x x x x x
Nystagmus rare x x
Oliguria rare x x
Osteoporosis rare x x x x x x x x x x x x x x x
Pancreatitis very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Priapism very rare, postmarketing x x x x x x x x x x x x x x x x x x x
Pruritus postmarketing, infrequent x x x x x x x x x x x x x x x x x
Pulmonary oedema rare x x x x x x x x x x x x x x x
Pulmonary embolism very rare — rare x x x x x x x x x x x x x x x x x x x
Rhabdomyolysis very rare, postmarketing x x x x x x x x x x x x x x x x x x
Convulsion postmarketing, rare x x
Aphthous stomatitis rare x x
Stridor rare x x
Subarachnoid haemorrhage rare x x
Urticaria postmarketing, infrequent x x x x x x x x x x x x x x x x x
Water intoxication rare x x
Normocytic anemia rare x x
Encephalopathy rare x x
Rash pustular rare x x
Deep vein thrombosis very rare, postmarketing x x x x x x x x x x x x x x x x x
Tongue discolouration rare x x
Lenticular pigmentation rare x x
Liver fatty deposition rare x x x x x x x x x x x x x x x
Bone pain rare x x
Circumoral paresthesia rare x x
Oesophageal ulcer rare x x
Urinary hesitation very rare, postmarketing x x x
Leukoderma rare x x
Hangover rare x x x x x x x x x x x x x x x
Hepatobiliary disease postmarketing x x x
Anaphylactoid reaction postmarketing x x x x x x x x x x x x x x x x x
Neuropathy rare x x
Paralysis rare x x
Sweating increased postmarketing x x x x x x x x x x x x x x
Thrombocytosis rare x x
Thromboembolic event postmarketing x x x x x x x x x x x x x x
Ileus rare x x x x x x x x x x x x x x x
Diabetic coma very rare, postmarketing x x x x x x x x x x x x x x x x x
Breast enlargement rare x x x x x
Hypoventilation rare x x
Neuroleptic malignant syndrome very rare, postmarketing x x
Bilirubin total increased very rare, postmarketing x x x
Venous thromboembolism very rare, postmarketing x x
Dementia Alzheimer's type x x x x x x x x x x x x x x x
Anorexia x x x
Mental disorder x
Breast disorder x x x
Infection x x x
Connective tissue disorder x x x
Depression x x x x x x x x x x x
Dyskinesia x x x x x x x x x
Dysmenorrhoea x x x x x x x x x x x x x x
Embolism
Extrapyramidal disorder x x x x x x x x x
Fasting x
Gastrointestinal disorder x x x
Cardiac disorder x x
Body temperature decreased x x
Immune system disorder x x
Mediastinal disorder x x
Muscle rigidity
Myoclonus x x x x x x
Drug withdrawal syndrome neonatal x x
Nervous system disorder x x x
Obesity
Parkinson's disease x x x x
Pregnancy x x
Sneezing 0% - 2% 0% x
Thromboembolism x x
Torsade de pointes
Torticollis x x x x x x
Unintended pregnancy x
Erythema x x
Urinary tract disorder x x
Angiopathy x x x
Ventricular tachycardia x x
Viral infection 0% - 2% 0% x
Weight decreased x x
Choreoathetosis x x x x x x
Hepatic failure x x x x x x x x x x x x x
Ventricular arrhythmia
Apathy x x x x x x x x x x x x x x x
Oculogyric crisis x x x x x x
Lower respiratory tract infection x x
Buccoglossal syndrome x x x x x x
Injection site reaction x
Injection site mass x
Opisthotonus x x x x x x
Paranoid reaction x x x
Generalised spasm x x x x x x
Haemoglobin decreased x
Malnutrition x x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x x x
Ketoacidosis x x