Mesalamine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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Side effect Data for drug Placebo Labels (show all 23)
1 2 3 4 5 6 7 8 9 10
Headache def postmarketing, 2.9% - 36% 0.559% - 12.5% x x x x x x x x
Eructation def postmarketing, 15% - 16% x x
Asthenia def 0.12% - 15% 3.12% x x x x x x x x
Pharyngitis def postmarketing, 9% - 11%
Oedema def postmarketing, 0.61% - 8.59% 8.59% x x x x x x x x
Oedema peripheral def 0.61% - 8.59% 8.59% x x x
Cramp muscle def postmarketing, 7.81% - 8.1% 7.81% x x x x x
Discomfort def postmarketing, 7.81% - 8.1% 7.81% x x x
Dizziness def postmarketing, 1.84% - 8% 2.34% x x x x x x x
Body temperature increased def postmarketing, 0% - 8% 0% x x x x x x x x x x
Tenderness def postmarketing, 0.61% - 7.03% 2.34% - 7.03% x x
Throat sore def postmarketing, 2.33% - 7.03% 7.03% x x
Back pain def 0.78% - 7% 0.78% - 0.781% x x x x x x
Flatulence def 0.7% - 7% 2.79% - 3.91% x x x x x x
Fatigue def postmarketing, 1% - 6.25% 6.25% x x x x x x
Malaise def postmarketing, 1% - 6.25% 6.25% x x x x
Gas def 3.91% - 6.13% 3.91% x x
Dyspepsia def 0.8% - 6% x x x
Rash def postmarketing, 1.2% - 6% 3.12% x x x x x x x x x
Arthralgia def postmarketing, 0.78% - 5% 0.78% - 0.781% x x x x x x x x x
Constipation def 0.98% - 5% 3.12% x x x x x
Hypertonia def 3% - 5%
Rhinitis def 5% x
Vomiting def postmarketing, 1.4% - 5% x x x x x x
Chest pain def postmarketing, 2% - 3% x x x
Dysmenorrhoea def 3%
Pruritus def postmarketing, 0% - 3% 0.78% - 1.12% x x x x x x x
Sweating def postmarketing, 1% - 3% x x
Chills def postmarketing, 2% - 3%
Myalgia def postmarketing, 1% - 3% x x x x
Proctalgia def 0% - 2.34% 0% - 2.34% x x x x
Insomnia def postmarketing, 0% - 2.34% 2.34% x x x x x
Liver function test abnormal 0.565% - 2.3% 1.12%
Arthritis def 0% - 2% x
Conjunctivitis def postmarketing, 0% - 2% x x
Cough def postmarketing, 0.3% - 2% x
Cough increased 1% - 2%
Acne def postmarketing, 1% - 2% x x x x x
Abdominal bloating def 1.47% - 1.56% 1.56% x x
Haemorrhoids def 0% - 1.35% 0% x x x
Abdominal distension def postmarketing, 1.3% x x x x x
Alopecia def postmarketing, 0% - 1.12% 0% x x x x x x x x x x
Hypertension def 1% x x
Agranulocytosis def postmarketing x x x x x x x
Albuminuria def postmarketing x x
Alveolitis allergic def postmarketing x x x
Anaemia def postmarketing x x x x x x
Aplastic anaemia def postmarketing x x x x x x
Angioedema def postmarketing x x
Anorexia def postmarketing x x x
Anxiety def postmarketing x
Bone disorder def postmarketing x
Candidiasis def postmarketing x x
Oral candidiasis def postmarketing x x
Cholecystitis def postmarketing x x
Dysphagia def postmarketing x x
Duodenal ulcer def postmarketing x x
Dyspnoea def postmarketing x x x x
Ecchymosis def postmarketing x x
Eczema def postmarketing x x
Effusion def postmarketing x x x
Eosinophilia def postmarketing x x x x
Erythema nodosum def postmarketing x x x x
Faecal incontinence def postmarketing x x
Gastritis def postmarketing x x
Gastroenteritis def postmarketing x x
Gastrointestinal haemorrhage def postmarketing x x x x
Cardiac disorder def postmarketing x
Haematochezia def postmarketing x
Haemorrhage def postmarketing x x x x x
Hepatitis def postmarketing x x x x x x x
Hirsutism def postmarketing
Hypersensitivity def postmarketing x x x x
Hypotension def postmarketing x x x
Orthostatic hypotension def postmarketing
Incontinence def postmarketing x x
Infection def postmarketing x x
Infertility def postmarketing x
Inflammatory bowel disease def postmarketing x x x x x x x
Unspecified disorder of intestine def postmarketing x x x x x x
Intestinal obstruction def postmarketing
Jaundice def postmarketing x x x x
Jaundice cholestatic def postmarketing x x x x
Nephropathy def postmarketing x x
Renal failure acute def postmarketing x x x
Renal failure chronic def postmarketing x x x
Cramps of lower extremities postmarketing x x
Leukocytosis def postmarketing x
Leukopenia def postmarketing x x x x
Hepatic cirrhosis def postmarketing x x
Systemic lupus erythematosus def postmarketing x x
Breast pain def postmarketing x x
Mediastinal disorder def postmarketing x x x
Melaena def postmarketing x
Menorrhagia def postmarketing x x x
Myelitis def postmarketing x x
Myelitis transverse def postmarketing x
Myocarditis def postmarketing x x x x x x
Nail disorder def postmarketing x x
Necrosis def postmarketing x x x x x
Nephritis def postmarketing x x x x x x
Nephritis interstitial def postmarketing x x x x x x
Nephrotic syndrome def postmarketing x x x
Nervous system disorder def postmarketing x x x
Neutropenia def postmarketing x x x
Obstruction def postmarketing
Oligospermia def postmarketing x x
Pancreatitis def postmarketing x x x x x x x x x x
Pancytopenia def postmarketing x x x x
Paraesthesia def postmarketing x x x
Peptic ulcer def postmarketing x x
Peptic ulcer perforation def postmarketing x x
Pericardial effusion def postmarketing x
Pericarditis def postmarketing x x x x x x x
Neuropathy peripheral def postmarketing x
Pneumonia def postmarketing x x x x x
Proteinuria def postmarketing
Psoriasis def postmarketing x x
Pulmonary eosinophilia def postmarketing
Pyoderma def postmarketing x x
Renal failure def postmarketing x x x x
Scotoma def postmarketing
Tachycardia def postmarketing x x x
Thirst def postmarketing x x
Thrombocytopenia def postmarketing x x x x x
Erythema def postmarketing x x x x x
Pollakiuria def postmarketing x x x
Urinary tract infection def postmarketing x
Micturition disorder def postmarketing
Urinary tract disorder def postmarketing x
Urticaria def postmarketing x x x x x x
Vaginal inflammation def postmarketing
Weight increased def postmarketing
Weight decreased def postmarketing x x
Hepatic failure def postmarketing x x x x
Pyoderma gangrenosum def postmarketing x x
Mouth ulceration def postmarketing x x x
Amylase increased postmarketing
Diarrhoea haemorrhagic postmarketing x
Gamma-glutamyltransferase increased def postmarketing x x x
Hepatocellular injury postmarketing x x x
Hepatic necrosis def postmarketing x x x x
Eye pain def postmarketing x
Skin discolouration def postmarketing x
Dry skin def postmarketing x x x
Oesophageal ulcer def postmarketing x x
Interstitial pneumonia postmarketing x x
Decreased appetite postmarketing
Abnormal dreams postmarketing
Rash erythematous postmarketing x
Lung infiltration postmarketing x x x
Hepatic enzyme increased postmarketing x x x x
Rectal haemorrhage def postmarketing x x x x x
Dry eye postmarketing
Photosensitivity def postmarketing x x
Lupus erythematosus def postmarketing x x x x x
Defaecation urgency def postmarketing x x
Neuropathy def postmarketing x x x
Urine colour abnormal def postmarketing
Discomfort rectal postmarketing
Alveolitis postmarketing x x x
Dissecting aortic aneurysm, thoracic postmarketing x x x
Thrombocytosis def postmarketing x x x
Local reaction postmarketing
Drug fever postmarketing x x
Somnolence def postmarketing x x x x x
Abdominal cramps def x
Pancreatitis acute def x x
Amblyopia def
Amenorrhoea def x x
Angina pectoris def x
Rheumatoid arthritis def
Asthma def x
Atrial fibrillation def x
Bronchospasm def x
Bronchiolitis def x x
Obliterative bronchiolitis def x x
Bronchitis def x
Vaginal moniliasis
Neck pain def x x
Cholelithiasis def x
Coma def x x
Confusional state def x
Connective tissue disorder def x x
Cystitis def
Deafness def
Libido decreased def
Delirium def x
Distention def x x x x
Dysgeusia def x x
Dysuria def x
Ear disorder def x
Ear pain def x x x
Eating disorder def x
Epididymitis def x
Epistaxis def
Oesophageal disorder def x x
Fibrosis def x x x
Cardiac flutter x
Gagging def x
Gastrointestinal disorder def x x x
Glossodynia def x
Gout def x
Haematuria def x x x x
Hyperaesthesia def x
Hyperhidrosis def x
Hypertrophy def x
Hypocalcaemia def x
Hypomenorrhoea x x
Arthropathy def x
Keratosis def x
Lacrimal disorder def
Lethargy def
Lichen unspecified def x x
Lichen planus def x x
Lung disorder def
Malabsorption def x
Metrorrhagia def x x
Musculoskeletal pain def x
Lipoid nephrosis def x
Nervousness def x
Palpitations def x x x
Pericarditis constrictive def x
Pleural disorder def x x
Pleural effusion def x x
Pleurisy def x
Pneumonia aspiration def x
Polyp def x x
Prostatic disorder def
Prurigo def x x
Pulmonary fibrosis def x x
Rectal disorder def x
Rectal polyp def x x
Respiratory tract infection def x
Skin disorder def x
Muscle spasms def x
Steatorrhoea def x
Stomatitis def
Sinus tachycardia def x
Thrombosis def x
Tinnitus def x x
Tremor def x x x x
Upper respiratory tract infection def x
Angiopathy def x
Vasodilation def x x x
Vertigo def x x
Dry mouth def x
Acute febrile neutrophilic dermatosis def x
Micturition urgency def x
Burning sensation def x
Mood swings x
Rash pustular def x
Alveolitis fibrosing x x
Hepatitis cholestatic x
Migraine def x
Blood urea increased x
Tongue discolouration x
Tongue oedema x
Kidney fibrosis x
Hypomagnesaemia def x
Lactic dehydrogenase activity increased x
Skin necrosis x
Phosphatase alkaline increased x x x
Aspartate aminotransferase increased def x
Alanine aminotransferase increased def x x
Rectal discharge x
Cardiac fibrillation x
Increased appetite x
Abdominal discomfort x
Abdominal pain lower x
Rectal tenesmus def x
Disorientation
Ache def
Faeces discoloured x
Urine abnormality
Back distress
Condition aggravated x
Dyschezia def x
Chronic interstitial nephritis x
Lung fibrosis interstitial x x
Hepatobiliary disease def x x
Blood bilirubin increased def x
Renal impairment def
Vision blurred def x x
Exacerbation of asthma x
Enlargement abdomen def x
Platelet count decreased x x
Lacrimation def
Gastrointestinal symptom NOS
Stiffness x
Transaminases increased x
Lymphadenopathy def x
Rash generalised x
Influenza like illness x
Chromaturia x
Face oedema def x x x
Anorectal disorder def x
Gastrointestinal pain def x
Aspiration x
Serum creatinine increased x
Bilirubin total increased x x
Haematocrit decreased x
Ear congestion
Infestation NOS x
Pharyngolaryngeal pain def x x x
Rectal cramps x
Anal discomfort x
Hepatic impairment
Neutrophilic dermatosis x
Rhinorrhoea def x
Lichenoid keratosis x
Death x
Parosmia def x
Eosinophilic pneumonia x x
Feeling hot x
Indication Labels
Acute ulcerative colitis x
Cancer in remission x x x x x x
Colitis def x x x x x x x x x
Colitis ulcerative def x x x x x x x x x
Elderly def x x
Generalized illness def x
Proctitis def x x
Proctitis ulcerative x
Proctosigmoiditis x
Ulcer def x x x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: A07EC02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. MESALAMINE / CANASA : 12 side effects (Drugs@FDA)
  2. MESALAMINE / LIALDA : 37 side effects (Drugs@FDA)
  3. MESALAZINE / SALOFALK (R) 5-ASA ENTERIC COATED TAB- 500MG : 40 side effects (Health Canada)
  4. MESALAMINE : 41 side effects (FDA XML label)
  5. MESALAMINE : 47 side effects (FDA XML label)
  6. MESALAZINE / MEZAVANT : 63 side effects (Health Canada)
  7. MESALAMINE : 102 side effects (FDA XML label)
  8. MESALAMINE : 104 side effects (FDA XML label)
  9. MESALAMINE : 105 side effects (FDA XML label)
  10. MESALAZINE / SALOFALK (R) 2GM/60GM RECTAL SUSPENSION : 127 side effects (Health Canada)