Phenytoin

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 13)
1 2 3 4 5 6 7 8 9 10
Acidosis def x x
Ageusia def x x
Agranulocytosis def x x x x x x x x
Albuminuria def x x
Alkalosis def x x
Amblyopia def x
Amnesia def x x
Anaphylactic shock def x x
Anaemia def x x x x x x x x x x
Hypochromic anaemia def x x
Anaemia megaloblastic def x x x x x x x x
Anorexia def x x
Aphasia def x x
Apnoea def x x
Arthralgia def x x x x x x
Asthenia def x
Asthma def x x
Ataxia def x x x x x x x x x
Atelectasis def x x
Atrial flutter def x x
Back pain def x
Bronchitis def x x
Bundle branch block def x x
Cachexia def x x
Candidiasis def x x
Vaginal moniliasis x x
Cerebral infarction def x x
Chorea def x x x x x x x x
Coma def x x x
Confusional state def x x x x x x x x x x
Conjunctivitis def x x
Constipation def x x x x x x x x x x
Convulsion def x x
Cough def x x
Cryptococcosis def x
Cyanosis def x x
Deafness def x x
Dysphagia def x x
Dehydration def x x
Delirium def x x
Depersonalisation def x x
Dermatitis def x x x x x x x x
Dermatitis contact def x x
Diabetes insipidus def x x
Diabetes mellitus def x x
Diarrhoea def x x
Diplopia def x
Dizziness def x x x x x x x x x
Dysarthria def x x x
Dysgeusia def x x x
Dyskinesia def x x x x x x x x
Dyspepsia def x x
Dyspnoea def x x
Dysuria def x x
Ear pain def x x
Ecchymosis def x
Oedema def x x
Encephalitis def x x
Eosinophilia def x x x x
Toxic epidermal necrolysis def x x x x x
Epilepsy def x x
Epistaxis def x x
Rash def x x x x x x x x x x
Extrapyramidal disorder def x x
Extravasation def x x x
Body temperature increased def x x x x x x x x x x
Flatulence def x x
Cardiac flutter x x
Gastritis def x x
Gastrointestinal haemorrhage def x
Gingival hyperplasia def x x x x x x x x
Headache def x x x x x x x x x
Cardiac arrest def x x
Cardiomegaly def x x
Cardiac failure def x x
Cardiac failure congestive def x x
Haematoma def x x
Subdural haematoma def x x
Hemiplegia def x x
Haemoptysis def x x
Haemorrhage def x x
Hepatitis def x x x x x x x x
Hostility def x x
Hyperaesthesia def x x
Hyperglycaemia def x x
Hyperkalaemia def x x
Hyperplasia def x x x x x x x x
Hypersensitivity def x x x x x
Hypertension def x x
Hypertrichosis def x x x x x x x x
Hypertrophy def x x x x x x x x
Hyperventilation def x x
Hypoaesthesia def x x
Hypocalcaemia def x
Hypokalaemia def x x
Hypotension def x x x x x
Orthostatic hypotension def x x
Incontinence def x x
Infarction def x x
Infection def x x
Inflammation def x x x x x
Influenza def x x
Ketosis def x x
Cramps of lower extremities x x
Lethargy def x
Leukocytosis def x x
Leukopenia def x x x x x x x x x x
Systemic lupus erythematosus def x x x x x x x x
Lymphoma def x x x x x x x x
Meningitis def x x
Cramp muscle def x x
Hypotonia def x x
Myopathy def x x
Mydriasis def x x
Myoclonus def x x
Nausea def x x x x x x x x x
Necrosis def x x x
Nervousness def x x x x x x x x x x
Neurosis def x x
Nodule def x x
Nystagmus def x x x x x x x x x
Oliguria def x x
Osteomalacia def x
Osteoporosis def x
Pain def x x
Palpitations def x x
Pancytopenia def x x x x x x x x
Paraesthesia def x x x x
Pelvic pain def x
Polyarteritis nodosa def x x x x x x x
Personality disorder def x x
Petechiae def x x
Pharyngitis def x x
Pneumonia def x x
Pneumonia aspiration def x
Pneumothorax def x x
Polyuria def x x
Pruritus def x
Psychotic disorder def x x
Pulmonary embolism def x x
Hyperacusis def x x
Extensor plantar response def x x
Renal failure def x x
Rhinitis def x x
Salivation def x x
Scotoma def x x
Shock def x x x x x
Salivary hypersecretion def x x
Sinusitis def x x
Skin nodule def x x
Speech disorder def x x
Sweating def x x
Syncope def x x
Tachycardia def x
Thrombocytopenia def x x x x x x x x x x
Thrombophlebitis def x x
Tinnitus def x
Tongue disorder x
Tremor def x x x x x x x x x
Urinary incontinence def x x
Urticaria def x x
Vaginal inflammation def x x
Vasodilation def x
Ventricular fibrillation def x x x
Vertigo def x
Vomiting def x x x x x x x x x
Dry mouth def x
Urinary retention def x x
Encephalopathy def x x
Chills def x x
Sinus bradycardia def x x
Stupor def x
Agitation def x
Mood swings x x
Photophobia def x x
Rash pustular def x x
Hypophosphataemia def x x x
Hypokinesia def x x
Hepatic function abnormal x x x x
Migraine def x x
CNS depression NOS x x x x x
Generalised oedema x x
Oedema genital def x
Tongue oedema x x
Necrolysis epidermal x x x x x
Ventricular extrasystoles def x x
Intracranial pressure increased def x x
Hepatocellular injury x x x x x x x x
Liver function test abnormal x x
Eye pain def x x
Urethral pain def x x
Circumoral paresthesia x x
Hyporeflexia x
Hyperreflexia x x
Skin discolouration def x
Polyneuropathy def x x x x x x x x
Photosensitivity reaction def x x
Pseudolymphoma def x x x x x x x x
Malaise def x x
Myalgia def x x
Muscle twitching def x x
Cardiac fibrillation x x x
Rectal tenesmus def x x
Asterixis def x x x x x x x x
Thinking abnormal x x
Discomfort def x
Tenderness def x x x
Slurred speech x x x x x x x x
Rash morbilliform x x x x x x
Sputum increased x x
Taste metallic x
Hypoxia def x x
Sepsis def x x
Extrasystoles def x x
Anaphylactoid reaction x
Photosensitivity def x x
Akathisia def x x
Dystonia def x x x x x x x x
Lupus erythematosus def x x x x x x x x
Rash maculo-papular def x x
Hyperkinesia def x x
Bradycardia def x x
Lymphadenopathy def x x x x x x x x x x
Coordination abnormal x
Paralysis def x x
Face oedema def x x
Hypersensitive syndrome x x x x
Cough increased x x
Macrocytosis x x x x x x x x
Aspiration x x
Intoxication x
Taste altered x
Hypotensive x
Insomnia def x x x x x x x x x x
Myasthenia def x x
Ileus def x x
Death x
Parosmia def x x
Brain oedema def x x
Embolus def x x
Tingling sensation def x
Somnolence def x x x
Cerebral haemorrhage def x
Indication Labels
Grand mal convulsion def x x x x x x x
Seizures def x x x x x x x x x x
Status epilepticus def x x x x x
Status epilepticus grand mal x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N03AB02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. PHENYTOIN : 43 side effects (FDA XML label)
  2. Phenytoin : 47 side effects (FDA XML label)
  3. Phenytoin : 48 side effects (FDA XML label)
  4. Phenytoin : 49 side effects (FDA XML label)
  5. Phenytoin : 50 side effects (FDA XML label)
  6. PHENYTOIN : 51 side effects (FDA XML label)
  7. PHENYTOIN : 53 side effects (FDA XML label)
  8. PHENYTOIN : 54 side effects (FDA XML label)
  9. PHENYTOIN : 167 side effects (FDA XML label)
  10. PHENYTOIN : 196 side effects (FDA XML label)