Levonorgestrel

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Abdominal pain def postmarketing x x x x x
Alopecia def postmarketing x x x x
Amenorrhoea def postmarketing x x x x
Angioedema def postmarketing x x
Arrhythmia def postmarketing x
Asthma def postmarketing x x
Back pain def postmarketing x x x x
Mental disorder def postmarketing x
Breast cancer def postmarketing x
Breast disorder def postmarketing x x
Breast feeding def postmarketing x x
Bronchitis def postmarketing x x
Neoplasm malignant def postmarketing x
Candidiasis def postmarketing x
Cervicitis def postmarketing x x x x
Connective tissue disorder def postmarketing x
Cystitis def postmarketing x x
Cyst def postmarketing x x x x x
Libido decreased def postmarketing x x x x
Diarrhoea def postmarketing x x x x
Dizziness def postmarketing x x x x x
Dysmenorrhoea def postmarketing x x x x x
Dysuria def postmarketing x
Eczema def postmarketing x x x
Oedema def postmarketing x x x
Endocrine disorder def postmarketing x
Endometriosis def postmarketing x
Endometritis def postmarketing x
Rash def postmarketing x x x x x
Fatigue def postmarketing x x x x x
Body temperature increased def postmarketing x
Gastrointestinal disorder def postmarketing x x
Headache def postmarketing x x x x x x x
Cardiac disorder def postmarketing x
Haemorrhage def postmarketing x x x x x x
Haemorrhoids def postmarketing x
Hirsutism def postmarketing x x x
Hypersensitivity def postmarketing x
Hypertension def postmarketing x x x x
Hypertrichosis def postmarketing x x
Immune system disorder def postmarketing x
Incontinence def postmarketing x
Influenza def postmarketing x x x
Leg pain postmarketing x
Mastitis def postmarketing x
Breast pain def postmarketing x x x x
Mediastinal disorder def postmarketing x
Chloasma postmarketing x
Menstrual disorder def postmarketing x
Metrorrhagia def postmarketing x x x x x
Musculoskeletal pain def postmarketing x
Nausea def postmarketing x x x x x x x
Neoplasm def postmarketing x x
Nervous system disorder def postmarketing x x
Nervousness def postmarketing x x x x
Oligomenorrhoea def postmarketing x x x x x
Otitis def postmarketing x x
Otitis media def postmarketing x
Ovarian cyst def postmarketing x x x x
Ovarian disorder def postmarketing x
Pain def postmarketing x x x x x x x
Pelvic pain def postmarketing x x x x x
Pharyngitis def postmarketing x x x
Pneumonia def postmarketing x
Polyp def postmarketing x
Pruritus def postmarketing x x x x
Respiratory tract infection def postmarketing x x
Rhinitis def postmarketing x x x
Sciatica def postmarketing x
Seborrhoeic dermatitis def postmarketing x
Sinusitis def postmarketing x x x
Skin disorder def postmarketing x
Sweating def postmarketing x
Tendonitis def postmarketing x
Tooth disorder def postmarketing x
Toothache def postmarketing x
Upper respiratory tract infection def postmarketing x x
Pollakiuria def postmarketing x
Urinary incontinence def postmarketing x
Urinary tract infection def postmarketing x
Urinary tract disorder def postmarketing x
Urticaria def postmarketing x x x
Uterine disorder def postmarketing x
Uterine leiomyoma def postmarketing x
Uterine perforation def postmarketing x
Vaginal neoplasm def postmarketing x
Vertigo def postmarketing x
Vomiting def postmarketing x x x x x x
Vulval disorder def postmarketing x x
Weight increased def postmarketing x x x x
Mood swings postmarketing x x x
Migraine def postmarketing x x x x x
Bleeding vaginal def postmarketing x x x
Dry skin def postmarketing x
Menstruation irregular def postmarketing x
Fibroadenoma of breast def postmarketing x
Fibroadenoma def postmarketing x
Vaginal discharge def postmarketing x x x
Tension def postmarketing x
Galactorrhoea postmarketing x
IUD complication postmarketing x
Enlargement abdomen def postmarketing x
Vaginal infection def postmarketing x
Sweating increased postmarketing x
Acne def postmarketing x x x x x
Dissecting aortic aneurysm, thoracic postmarketing x
Genital infection postmarketing x
Infestation NOS postmarketing x
Genital discharge postmarketing x
Abdominal bloating def postmarketing x
Dyspareunia def postmarketing x x x x
Breast neoplasm def postmarketing x x
Abdominal distension def x x
Acute tonsillitis x
Anaemia def x x x
Hypochromic anaemia def x
Anorexia def x
Anxiety def x
Appendicitis def x
Asthenia def x x
Chest pain def x
Constipation def x x
Corpus luteum cyst x
Cough def x
Dermatitis def x
Dermatitis contact def x
Dyspepsia def x
Dyspnoea def x
Flatulence def x
Folliculitis def x
Haematoma def x
Herpes NOS def x
Herpes simplex def x
Hypertrophy def x
Hypoaesthesia def x
Hypomenorrhoea x
Cramps of lower extremities x
Leukorrhea def x
Menorrhagia def x
Cramp muscle def x
Fungal infection def x
Numbness def x
Palpitations def x x
Papilloma def x
Polymenorrhoea x
Premenstrual syndrome def x
Pruritus genital x
Purpura def x
Gastric disorder def x
Syncope def x
Tonsillitis def x
Ulcer def x
Vaginal inflammation def x
Varicose vein def x
Visual impairment def x
Vulvovaginitis def x x
Weight decreased def x
Polydipsia def x
Acute appendicitis def x
Genital ulceration x
Application site reaction x
Uterine enlargement def x
Haemoglobin decreased def x
Lightheadedness x
Blood urine x
Myalgia def x
Muscle twitching def x
Increased appetite x
Abdominal pain lower x
Menometrorrhagia x
Tenderness def x x x x x
Ache def x
Uterine cervical lesion x
Menstruation delayed x
Perineal pain def x
Breast tenderness x x x
Redness def x
Depressed mood def x x
Benign breast neoplasm def x
Tearfulness x
Chapped lips x
Gas in stomach x
Blood glucose increased x
Exacerbation of acne x
Urinary protein increased x
Glucose increased x
Insomnia def x
Fibroadenosis of breast x
Somnolence def x
Indication Labels
Coitus interruptus def x
Ectopic pregnancy def x
Fertilization def x
Infection def x
IUD expelled def x
Nulliparous x
Pelvic inflammatory disease def x
Sexual assault x
Sexually transmitted disease def x
Unintended pregnancy def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: G03AC03

Legend

Color scheme: standardalternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. LEVONORGESTREL : 11 side effects (FDA XML label)
  2. LEVONORGESTREL : 18 side effects (FDA XML label)
  3. LEVONORGESTREL / PLAN B : 56 side effects (Health Canada)
  4. LEVONORGESTREL / NORPLANT II : 81 side effects (Drugs@FDA)
  5. LEVONORGESTREL / MIRENA : 38 side effects (Drugs@FDA)
  6. levonorgestrel-releasing intrauterine system / Mirena : 38 side effects (FDA MedWatch)
  7. LEVONORGESTREL / MIRENA : 109 side effects (Health Canada)