Efavirenz

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 14)
1 2 3 4 5 6 7 8 9 10
Rash def 0% - 45.6% x x x x x x x x
Dizziness def 6% x x x x x x x x
Pain def postmarketing, 3% - 6% x x x x x
Pruritus def 5% x x x x x x
Abdominal pain def 3% x x x x x
Diarrhoea def 3% x x x x x
Anorexia def 2% x x x x x
Fatigue def 2% x x x x x
Headache def postmarketing, 2% x x x x x
Nausea def 2% x x x x x x
Aggression def postmarketing x x x x x x x x
Alopecia def postmarketing x
Amnesia def postmarketing x x x x x x x x
Anaemia def postmarketing x
Anxiety def postmarketing x x x x x
Apnoea def postmarketing x
Arrhythmia def postmarketing x x
Arthralgia def postmarketing x x x x
Asthenia def postmarketing x x x x
Asthma def postmarketing x
Ataxia def postmarketing x x x x
Chest pain def postmarketing x
Confusional state def postmarketing x x x x x x x x
Constipation def postmarketing x x x x
Convulsion def postmarketing x x x x
Delirium def postmarketing x
Delusion def postmarketing x x x x x x
Depersonalisation def postmarketing x x x x x x x x
Dermatitis def postmarketing x x x x x x
Diplopia def postmarketing x
Dysgeusia def postmarketing x
Dyspnoea def postmarketing x x x x
Eczema def postmarketing x
Oedema def postmarketing x
Enzyme induction def postmarketing x x x x
Erythema multiforme def postmarketing x x x x x
Erythema nodosum def postmarketing x
Fasting def postmarketing x x
Body temperature increased def postmarketing x x x x x x
Flank pain def postmarketing x
Flushing def postmarketing x x x x
Folliculitis def postmarketing x
Glaucoma def postmarketing x
Gynaecomastia def postmarketing x x x x
Hallucination def postmarketing x x x x x x x x
Cardiac failure def postmarketing x
Cardiac failure congestive def postmarketing x
Hepatitis def postmarketing x x x x x
Hepatitis B def postmarketing x x x x x
Hepatitis C def postmarketing x x x
Hepatomegaly def postmarketing x
Hypercholesterolaemia def postmarketing x x x x
Hypersensitivity def postmarketing x x x
Hypertension def postmarketing x
Hypertriglyceridaemia def postmarketing x x x x
Hypoaesthesia def postmarketing x x x x
Influenza def postmarketing x
Iritis def postmarketing x
Jaundice def postmarketing x
Liver disorder def postmarketing x
Malabsorption def postmarketing x x x x
Myopathy def postmarketing x x x x
Nail disorder def postmarketing x x x
Neuralgia def postmarketing x
Neurosis def postmarketing x x x x
Palpitations def postmarketing x x x x
Pancreatitis def postmarketing x x x x x
Pancytopenia def postmarketing x
Paresis def postmarketing x
Paraesthesia def postmarketing x x x x x
Neuropathy peripheral def postmarketing x
Polyuria def postmarketing x
Proteinuria def postmarketing x
Psychotic disorder def postmarketing x x x x x
Rhabdomyolysis def postmarketing x
Skin disorder def postmarketing x
Speech disorder def postmarketing x
Suicide def postmarketing x x x x x x x x
Sweating def postmarketing x x
Syncope def postmarketing x x
Tachycardia def postmarketing x
Thrombocytopenia def postmarketing x
Thrombophlebitis def postmarketing x
Tinnitus def postmarketing x x x x
Tremor def postmarketing x x x x
Erythema def postmarketing x x x x x x
Urticaria def postmarketing x x
Vertigo def postmarketing x
Visual impairment def postmarketing x x x
Common wart def postmarketing x
Dry mouth def postmarketing x
Hepatic failure def postmarketing x x x x
Stupor def postmarketing x x x x x x x
Agitation def postmarketing x x x x x x x x
Apathy def postmarketing x
Mood swings postmarketing x x x x
Oedema peripheral def postmarketing x
Migraine def postmarketing x x
Alcohol intolerance def postmarketing x
Creatine phosphokinase increased def postmarketing x
Manic psychosis postmarketing x
Muscular weakness def postmarketing x
Paranoid reaction postmarketing x
Skin discolouration def postmarketing x x
Polyarthritis def postmarketing x
Photocontact dermatitis def postmarketing x x x
Photosensitivity reaction def postmarketing x
Malaise def postmarketing x
Myalgia def postmarketing x x x x
Thinking abnormal postmarketing x x x x x x x x
Muscle contractions involuntary postmarketing x
Euphoric mood def postmarketing x x x x x x x x
Depression aggravated postmarketing x
Hepatic enzyme increased postmarketing x x
Skin exfoliation postmarketing x x x x x x
Hepatitis C antibody positive postmarketing x x x
Mania def postmarketing x x x x x
Vision blurred def postmarketing x
Photosensitivity def postmarketing x
Neuropathy def postmarketing x x x x
Coordination abnormal postmarketing x x x
Gas def postmarketing x x
Hot flush def postmarketing x
Drug interaction def postmarketing x x x x x x
Sweating increased postmarketing x x
Acne def postmarketing x
Antibody test positive postmarketing x x x
Fat redistribution postmarketing x x
Immune reconstitution syndrome postmarketing x x x x
Paranoia def postmarketing x x x x x
Parosmia def postmarketing x
Weakness def postmarketing x
Congenital anomaly def x
Elderly def x
Anencephaly def x
Anophthalmos def x
Mental disorder def x
Blister def x x x x x
Breast feeding def x
Cachexia def x
Neoplasm malignant def x
Cleft palate def x
Cough def x
Dermatitis exfoliative def x x x x x x
Drowsiness def x x x
Dyspepsia def x x x x x
Toxic epidermal necrolysis def x x x x x x
Fertilization def x
HIV infection def x
Hypertrophy def x
Inflammation def x
Lipodystrophy def x x
Lipidosis def x
Lipoma def x
Mycobacterium avium complex infection def x x x
Necrosis def x x x x x x
Nervousness def x x x x x
Obesity def x x
Opportunistic infection def x x x
Ovarian disorder def x
Petechiae def x
Pneumonia def x x x
Pneumocystis carinii pneumonia def x x x
Gastric disorder def x x x
Suicide attempt def x x x x x x x
Tuberculosis def x x x
Ulcer def x x x x x x
Vomiting def x x x x x
Rash pustular def x
Necrolysis epidermal x x x x x x
Lightheadedness x
Welts def x
Sickness x
Teratogenicity def x
Psychiatric symptom x x x x x x x x x
Discomfort def x
Ache def x
Abnormal dreams x x x x x x
Rash erythematous x
Rash follicular x
Neurological symptom x x x x x x x x x x
Cerebration impaired def x x x x x x x x
Eruption x x x x x
Central obesity def x
Papule def x
Macule def x
Redness def x
Enlargement abdomen def x
Rash maculo-papular def x x x x x
Suicidal ideation def x x x x x x x
Substance abuse def x
Allergic rash x
Carcinogenicity x
Insomnia def x x x x x x x x
Hepatic impairment x
Pneumocystis jiroveci pneumonia x x x
Breast enlargement x
Somnolence def x x x x x x x x
Indication Labels
Adverse event def x x x x x x x
Adverse reaction def x x x x x x x
Death x x x x x
Immunodeficiency def x
Infection def x x x x x x x x
Lymphangioleiomyomatosis def x x x x x x x x
Virologic failure x x x x x
Withdrawn x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: J05AG03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. efavirenz / Sustiva : 8 side effects (FDA MedWatch)
  2. EFAVIRENZ / SUSTIVA : 9 side effects (Drugs@FDA)
  3. efavirenz / Sustiva : 29 side effects (FDA MedWatch)
  4. EFAVIRENZ / SUSTIVA : 37 side effects (Drugs@FDA)
  5. efavirenz / Sustiva : 47 side effects (FDA MedWatch)
  6. EFAVIRENZ / SUSTIVA : 50 side effects (Drugs@FDA)
  7. efavirenz / Sustiva : 84 side effects (FDA CDER)
  8. EFAVIRENZ / SUSTIVA : 85 side effects (Drugs@FDA)
  9. efavirenz : 93 side effects (FDA XML label)
  10. EFAVIRENZ / SUSTIVA 50MG : 157 side effects (Health Canada)