Propofol

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Acidosis def postmarketing x x x x x x x
Respiratory acidosis def postmarketing x x x x x x
Airway obstruction NOS def postmarketing x x x x x
Amblyopia def postmarketing x x x x x x
Anaphylactic shock def postmarketing x x x x x x x
Anxiety def postmarketing x x x x x x
Apnoea def postmarketing x x x x x x x
Arrhythmia def postmarketing x x x x x x
Asthenia def postmarketing x x x x x x
Atrial fibrillation def postmarketing x x x x x x
Atrioventricular block def postmarketing x x x x x x
Coagulopathy def postmarketing x x x x x x
Bronchospasm def postmarketing x x x x x x
Bundle branch block def postmarketing x x x x
Cardiac output decreased def postmarketing x x x x x
Chest pain def postmarketing x x x x x x
Confusional state def postmarketing x x x x x x
Cough def postmarketing x x x x x x
Dehydration def postmarketing x x x x x x
Delirium def postmarketing x x x x x x
Diarrhoea def postmarketing x x x x x x
Diplopia def postmarketing x x x x x x
Dizziness def postmarketing x x x x x x
Drug abuse def postmarketing x
Dysgeusia def postmarketing x x x x x x
Dyspnoea def postmarketing x x x x x x
Ear pain def postmarketing x x x x x x
Rash def postmarketing x x x x x x
Fatigue def postmarketing x x x x x x
Body temperature increased def postmarketing x x x x x x
Flushing def postmarketing x x x x x x
Hallucination def postmarketing x x x x x x
Headache def postmarketing x x x x x x
Cardiac arrest def postmarketing x x x x x x
Block heart def postmarketing x x x x x x
Cardiac failure def postmarketing x x x x x x
Haemorrhage def postmarketing x x x x x x
Hiccups def postmarketing x x x x x x
Hyperaemia def postmarketing x x x x x x
Hyperglycaemia def postmarketing x x x x x x
Hyperkalaemia def postmarketing x x x x x x
Hyperlipidaemia def postmarketing x x x x x x
Hypertension def postmarketing x x x x x x x
Hyperventilation def postmarketing x x x x x x
Hypotension def postmarketing x x x x x x
Hysteria def postmarketing x x x x x x
Infarction def postmarketing x x x x x x
Ischaemia def postmarketing x x x x x x
Laryngospasm def postmarketing x x x x x x
Leukocytosis def postmarketing x x x x x x
Cramp muscle def postmarketing x x x x x x
Hypertonia def postmarketing x x x x x x
Hypotonia def postmarketing x x x x x x
Muscle rigidity def postmarketing x x x x x x
Myocardial infarction def postmarketing x x x x
Nausea def postmarketing x x x x x x
Nystagmus def postmarketing x x x x x x
Obstruction def postmarketing x x x x x x
Oliguria def postmarketing x x x x x x
Pain def postmarketing x x x x x x
Pain in extremity def postmarketing x x x x x x
Paraesthesia def postmarketing x x x x x
Pharyngitis def postmarketing x x x x x x
Phlebitis def postmarketing x x x x x x
Supraventricular extrasystoles def postmarketing x x x x x x
Pruritus def postmarketing x x x x x x
Renal failure def postmarketing x x x x x x
Rhabdomyolysis def postmarketing x
Seizures def postmarketing x x x x x x
Shivering def postmarketing x x x x x x
Shock def postmarketing x
Salivary hypersecretion def postmarketing x x x x x x
Sneezing def postmarketing x x x x x x
Syncope def postmarketing x x x x x x
Tachycardia def postmarketing x x x x x x
Supraventricular tachycardia def postmarketing x x x x x x
Tinnitus def postmarketing x x x x x x
Tremor def postmarketing x x x x x x
Urticaria def postmarketing x x x x x x
Ventricular fibrillation def postmarketing x x x x x x
Ventricular tachycardia def postmarketing x x x x x x
Visual impairment def postmarketing x x x x x x
Vomiting def postmarketing x x x x x x
Wheezing def postmarketing x x x x x x
Dry mouth def postmarketing x x x x x x
Urinary retention def postmarketing x x x x x x
Chills def postmarketing x x x x x x
Atrial arrhythmia def postmarketing x x x x x x
Agitation def postmarketing x x x x x x
Mood swings postmarketing x x x x x x
Hepatic function abnormal postmarketing x x x x x x
Neck stiffness postmarketing x x x x x x
Blood urea increased postmarketing x x x x x x
Creatinine increased def postmarketing x x x x x x
Ventricular extrasystoles def postmarketing x x x x x x
Hypomagnesaemia def postmarketing x x x x x x
Drug effect increased postmarketing x x x x
Intracranial pressure increased def postmarketing x x x x x x x
Myocardial ischaemia def postmarketing x x x x x x
Opisthotonus postmarketing x x x x x x x
Eye pain def postmarketing x x x x x x
Metabolic acidosis def postmarketing x x x x x x x
Myalgia def postmarketing x x x x x x
Muscle twitching def postmarketing x x x x x x
Tachypnoea def postmarketing x x x x x x
Cardiac fibrillation postmarketing x x x x x x
Thinking abnormal postmarketing x x x x x x
Abnormal dreams postmarketing x x x x x x
Respiratory depression postmarketing x x x x x x
Euphoric mood def postmarketing x x x x x x
Cardiac failure right def postmarketing x x x x x x
Hypoxia def postmarketing x x x x x x
Sepsis def postmarketing x x x x x x
Ventricular bigeminy def postmarketing x x x x x x
Unspecified condition originating in the perinatal period def postmarketing x x x x x x
Cloudy urine postmarketing x x x x x x
Redness def postmarketing x x x x x x
Extrasystoles def postmarketing x x x x x x
Anaphylactoid reaction postmarketing x x x x x x
Dystonia def postmarketing x x x x x x
Hypoventilation def postmarketing x x x x x x
Stiffness postmarketing x x x x x x
Bradycardia def postmarketing x x x x x x
Nodal tachycardia postmarketing x x x x x x
Electrocardiogram ST segment postmarketing x x x x x x
Neuropathy def postmarketing x x x x x x
Electrocardiogram ST segment depression def postmarketing x x x x x x
Electrocardiogram abnormal postmarketing x x x x x x
Reaction perinatal postmarketing x x x
Stinging postmarketing x x x x x x
Anguish def postmarketing x
Sweating increased postmarketing x x x x x x
Upper airway obstruction postmarketing x x x x x
Moaning postmarketing x x x x x x
Insomnia def postmarketing x x x x x x
Ileus def postmarketing x x x x x x
Death postmarketing x
Conjunctival hyperaemia postmarketing x x x x x x
Weakness def postmarketing x x x x x x
Somnolence def postmarketing x x x x x x
Angioedema def x
Convulsion def x
Oedema def x x x x
Myoclonus def x
Pulmonary oedema def x
Erythema def x
Indication Labels
Breast feeding def x x x x x x
Mycobacterium avium complex infection def x x x x x x
Sedation x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N01AX10

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. PROPOFOL / PROPOFOL INJECTION : 17 side effects (Health Canada)
  2. PROPOFOL : 130 side effects (FDA XML label)
  3. PROPOFOL / DIPRIVAN : 132 side effects (Drugs@FDA)
  4. Propofol : 133 side effects (FDA XML label)
  5. Propofol : 135 side effects (FDA XML label)
  6. PROPOFOL : 135 side effects (FDA XML label)
  7. Propofol : 136 side effects (FDA XML label)