Sertraline

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 43)
1 2 3 4 5 6 7 8 9 10
Insomnia def postmarketing, 1% - 28% 9% - 18% x x x x x x x x x
Diarrhoea def postmarketing, 1% - 24% 3% - 15% x x x x x x x x x
Ejaculation failure 1% - 19% 1% - 2% x x x x x x x
Dry mouth def 1% - 16% 3% - 10% x x x x x x x x
Somnolence def postmarketing, 0% - 15% 0% - 9% x x x x x x x x x
Ejaculation delayed 1% - 14% 1% x x x x x x x x
Dyspepsia def 1% - 13% 2% - 8% x x x x x x x x x
Anorexia def 0% - 11% 0% - 5% x x x x x x x x x
Libido decreased def postmarketing, 1% - 11% 1% - 4% x x x x x x x x
Tremor def postmarketing, 1% - 11% 0% - 3% x x x x x x x x x
Sweating increased 0% - 11% 0% - 3% x x x x x x x x
Malaise def infrequent — 1% - 10% 1% - 14% x x x x x x x x
Constipation def 1% - 8% 1% - 6% x x x x x x x x
Abdominal pain def postmarketing, 1% - 7% 1% - 7% x x x x x x x x
Asthenia def frequent x x x x x x x x
Back pain def frequent x x x x x x x x
Confusional state def postmarketing — frequent x x x x x x x x
Hypersensitivity def rare, frequent x x x x x x x x x
Hypoaesthesia def frequent x x x x x x x x
Hypertonia def frequent x x x x x x x x
Rhinitis def frequent x x x x x x x x
Tinnitus def frequent x x x x x x x x
Yawning def frequent x x x x x x x x
Increased appetite frequent x x x x x x x x
Erectile dysfunction def frequent x x x x x x x x
Sexual dysfunction frequent x x x x x x x x x x
Female sexual dysfunction frequent x x x x x x x x x
Male sexual dysfunction frequent x x x x x x x x x
Nervousness def 2% x x x x x x x x
Aggression def infrequent x x x x x x x x x
Alopecia def postmarketing, infrequent x x x x x x x x
Amenorrhoea def rare, infrequent x x x x x x x x
Amnesia def infrequent x x x x x x x x
Arthralgia def infrequent x x x x x x x x
Ataxia def infrequent x x x x x x x x
Bronchospasm def infrequent x x x x x x x x
Conjunctivitis def infrequent x x x x x x x x
Cough def infrequent x x x x x x x x
Dysphagia def infrequent x x x x x x x x
Delusion def infrequent x x x x x x x x
Dental caries def infrequent x x x x x x x x
Diplopia def rare, infrequent x x x x x x x x
Dysmenorrhoea def infrequent x x x x x x x x
Dysuria def infrequent x x x x x x x x
Ear pain def infrequent x x x x x x x x
Oedema def rare, infrequent x x x x x x x x
Epistaxis def infrequent x x x x x x x x x
Eructation def infrequent x x x x x x x x
Oesophagitis def infrequent x x x x x x x x
Rash def rare, infrequent x x x x x x x x
Body temperature increased def infrequent x x x x x x x x x
Gastroenteritis def rare, infrequent x x x x x x x x
Hallucination def postmarketing, infrequent x x x x x x x x
Haemorrhage def rare, infrequent x x x x x x x x x
Hyperaesthesia def infrequent x x x x x x x x
Hypertension def postmarketing — infrequent x x x x x x x x
Hypotension def postmarketing, infrequent x x x x x x x x
Orthostatic hypotension def infrequent x x x x x x x x
Incontinence def rare, infrequent x x x x x x x x x
Infection def infrequent x x x x x x x x
Ischaemia def infrequent x x x x x x x x
Arthropathy def infrequent x x x x x x x x
Cramps of lower extremities infrequent x x x x x x x x
Leukorrhea def rare, infrequent x x x x x x x x
Menstrual disorder def infrequent x x x x x x x x
Metrorrhagia def infrequent x x x x x x x x
Cramp muscle def infrequent x x x x x x x x
Mydriasis def postmarketing, infrequent x x x x x x x x
Neurosis def infrequent
Nightmare def infrequent x x x x x x x x
Nocturia def infrequent x x x x x x x x
Nystagmus def infrequent x x x x x x x x
Polyuria def infrequent x x x x x x x x
Pruritus def infrequent x x x x x x x x
Purpura def infrequent x x x x x x x x x
Respiratory tract infection def infrequent x x x x x x x x
Salivary hypersecretion def infrequent x x x x x x x x
Sinusitis def rare, infrequent x x x x x x x x x
Syncope def postmarketing, infrequent x x x x x x x x
Tachycardia def postmarketing, infrequent x x x x x x x x
Thirst def infrequent x x x x x x x x
Upper respiratory tract infection def infrequent x x x x x x x x
Pollakiuria def infrequent x x x x x x x x
Urinary incontinence def infrequent x x x x x x x x x
Urticaria def rare, infrequent x x x x x x x x
Vertigo def infrequent x x x x x x x x
Weight decreased def infrequent x
Xerophthalmia def rare, infrequent x x x x x x x x
Urinary retention def rare, infrequent x x x x x x x x
Apathy def infrequent x x x x x x x x
Mood swings infrequent x x x x x x x x
Oedema peripheral def infrequent x x x x x x x x
Hypokinesia def infrequent x x x x x x x x
Migraine def infrequent x x x x x x x x
Periorbital oedema def infrequent x x x x x x x x
Generalised oedema infrequent x x x x x x x x
Muscular weakness def infrequent x x x x x x x x
Eye pain def infrequent x x x x x x x x
Paranoid reaction infrequent x x x x x x x x
Dry skin def infrequent x x x x x x x x
Photosensitivity reaction def rare, infrequent x x x x x x x x
Muscle twitching def infrequent x x x x x x x x
Thinking abnormal infrequent x
Abnormal dreams postmarketing, infrequent x x x x x x x x
Rash erythematous infrequent x x x x x x x x
Dizziness postural infrequent x x x x x x x x
Euphoric mood def infrequent x x x x x x x x
Tooth caries aggravated NOS infrequent x x x x x x x x
Gravitational oedema infrequent x x x x x x x x
Peripheral ischaemia def infrequent x x x x x x x x
Skin cold clammy infrequent x x x x x x x x
Depression aggravated infrequent x x x x x x x x
Photosensitivity def postmarketing — infrequent x x x x x x x x
Sticky skin infrequent x x x x x x x x
Dystonia def infrequent x x x x x x x x
Rash maculo-papular def infrequent x x x x x x x x
Hyperkinesia def infrequent x x x x x x x x x
Rigors infrequent x x x x x x x x
Lymphadenopathy def infrequent
Coordination abnormal infrequent x x x x x x x x
Face oedema def rare, infrequent x x x x x x x x
Gait disturbance def infrequent x x x x x x x x
Acne def infrequent x x x x x x x x
Aggressive reaction infrequent x x x x x x x x x
Weakness def infrequent x x x x x x x x
Vaginal haemorrhage def infrequent x x x x x x x x
Agranulocytosis def postmarketing x x x x x x
Anaemia def postmarketing, rare x x x x x x x x x
Aplastic anaemia def postmarketing x x x x x x
Angioedema def postmarketing x x x x x x
Apnoea def rare x x x x x x x x
Arrhythmia def postmarketing x x x x x x x
Atrioventricular block def postmarketing x x x x x x x
Balanoposthitis rare x x x x x x x x
Bronchitis def rare x x x x x x x x
Bundle branch block def postmarketing
Cerebrovascular disorder def rare x x x x x x x x
Colitis def rare x x x x x x x x
Coma def rare, postmarketing x x x x x x x x
Convulsion def postmarketing, rare
Cystitis def rare x x x x x x x x
Dehydration def rare
Delirium def postmarketing
Dermatitis def rare x x x x x x x x
Dermatitis contact def rare x x x x x x x x
Diabetes mellitus def postmarketing
Diuresis def postmarketing
Diverticulitis def rare x x x x x x x x
Dyskinesia def rare x x x x x x x x
Eczema def rare x x x x x x x x
Erythema multiforme def rare
Exophthalmos def rare x x x x x x x x x
Eye haemorrhage def rare x x x x x x x x x
Faecal incontinence def rare x x x x x x x x
Gastritis def rare x x x x x x x x
Gastrointestinal haemorrhage def rare
Gingival hyperplasia def rare x x x x x x x x
Glaucoma def rare x x x x x x x x
Glossitis def rare x x x x x x x x
Gynaecomastia def rare x x x x x x x x x
Breath odour def rare
Haematuria def rare, postmarketing x x x x x x x x
Haemoptysis def rare x x x x x x x x
Haemorrhoids def rare
Hepatitis def postmarketing x x x x x x x
Hepatomegaly def postmarketing x x x x x x x
Hernia def rare
Hiccups def rare x x x x x x x x
Hypercholesterolaemia def rare
Hyperglycaemia def postmarketing x x x x x x x
Hyperplasia def rare x x x x x x x x
Hyperprolactinaemia def postmarketing x x x x x x x
Pulmonary hypertension def postmarketing x x x x x x
Hypertrichosis def rare x x x x x x x x
Hypertrophy def rare x x x x x x x x
Hyperventilation def rare x x x x x x x x
Hyphaema def rare x x x x x x x x x
Hypoglycaemia def rare, postmarketing x x x x x x x x
Hypothyroidism def postmarketing x x x x x x x
Hysteria def rare
Illusion def rare x x x x x x x x
Inappropriate antidiuretic hormone secretion def postmarketing
Libido increased def rare x x x x x x x x
Infarction def rare x x x x x x x x
Jaundice def postmarketing x x x x x x x
Renal failure acute def postmarketing x x x x x x
Labyrinthine disorder def rare x x x x x x x x
Laryngospasm def rare x x x x x x x x
Laryngitis def rare x x x x x x x x
Leukopenia def postmarketing x x x x x x x
Mastitis def rare x x x x x x x x
Breast pain def rare x x x x x x x x
Melaena def rare x x x x x x x x
Menorrhagia def rare x x x x x x x x
Hypotonia def rare x x x x x x x x
Myocardial infarction def rare x x x x x x x x
Neuritis def postmarketing x x x x x x
Neuroleptic malignant syndrome def postmarketing x x
Oliguria def rare x x x x x x x x
Optic neuritis def postmarketing x x x x x x
Otitis def rare
Otitis media def rare
Pallor def rare x x x x x x x x
Pancreatitis def postmarketing x x x x x x x
Pancytopenia def postmarketing x x x x x x
Peptic ulcer def rare x x x x x x x x
Priapism def rare, postmarketing x x x x x x x x x
Proctitis def rare x x x x x x x x
Ptosis def rare x x x x x x x x
Psychotic disorder def postmarketing x x x x x x x
Pyelonephritis def rare x x x x x x x x
Hyperacusis def rare x x x x x x x x x
Rectal disorder def rare x x x x x x x x
Renal failure def postmarketing x x x x x x
Scotoma def rare x x x x x x x x
Serum sickness def postmarketing x x x x x x
Shock def postmarketing
Skin disorder def postmarketing x x x x x x x
Somnambulism def rare x x x x x x x x
Stomatitis def rare x x x x x x x x
Aphthous stomatitis def rare x x x x x x x
Ulcerative stomatitis rare x x x x x x x x
Stridor def rare x x x x x x x x
Withdrawal syndrome def rare x x x x x x x x
Thrombocytopenia def postmarketing x x x x x x x
Torsade de pointes def postmarketing x x x x x x
Ulcer def rare x x x x x x x x
Erythema def rare
Vaginal inflammation def rare x x x x x x x x
Varicose vein def rare
Vasculitis def postmarketing x x x x x x x
Vasodilation def rare x x x x x x x x
Ventricular tachycardia def postmarketing x x x x x x
Vomiting def postmarketing x x x x x x x
Choreoathetosis rare x x x x x x x x
Hepatic failure def postmarketing x x x x x x x
Atrial arrhythmia def postmarketing x x x x x x x
Stupor def postmarketing
Photophobia def rare x x x x x x x x
Oculogyric crisis postmarketing x x x x x x
Rash pustular def rare x x x x x x x x
Cataract def postmarketing x x x x x x
Hepatic function abnormal rare x x x x x x x x x
Tongue oedema rare x x x x x x x x
Necrolysis epidermal postmarketing
Manic psychosis postmarketing x
Retrosternal pain rare x x x x x x x x
Hyporeflexia rare x x x x x x x x
Skin discolouration def rare x x x x x x x x
Vaginitis atrophic def rare x x x x x x x x
Respiratory rate decreased def rare x x x x x x x x
Precordial pain rare x x x x x x x x
Digestion impaired postmarketing
Rectal tenesmus def rare x x x x x x x x
Strangury rare x x x x x x x x
Extrapyramidal symptoms postmarketing x x x x x x
Rash follicular rare x x x x x x x x
Skin odour abnormal rare
Muscle contractions involuntary postmarketing
Tongue ulceration rare x x x x x x x x
Galactorrhoea postmarketing x x x x x x x
Mastitis acute female rare x x x x x x x x
Hypertension worsened rare x x x x x x x x
Hair texture abnormal rare
Bullous eruption rare x x x x x x x x
Ejaculation disorder def postmarketing
Crocodile tears syndrome rare x x x x x x x x
Rectal haemorrhage def rare x x x x x x x x
Hypoglycemic reaction def rare x x x x x x x x
Eruption rare x x x x x x x x
Blood bilirubin increased def postmarketing x x x x x x x
Mania def postmarketing x
Anaphylactoid reaction postmarketing x x x x x x
Enlargement abdomen def rare
Hypoventilation def rare x x x x x x x x
Lupus erythematosus def postmarketing x x x x x x
Lacrimation def rare x x x x x x x x
Bradycardia def postmarketing x x x x x x x
Blindness def postmarketing x x x x x x
Breast pain female rare x x x x x x x x
Renal pain rare x x x x x x x x
Breast disorder female rare x x x x x x x x
Malignant syndrome NOS postmarketing x x
Dysphonia def rare x x x x x x x x
Breast enlargement rare x x x x x x x x
Mental disorder def x x x x x x x x x
Dysgeusia def
Endocrine disorder def x x x x x x x x
Flatulence def x
Gastrointestinal disorder def x x x x x x x x x
Unspecified disorder of intestine def
Musculoskeletal disorder def x x x x x x x x x
Nervous system disorder def x x x x x x x x x
Neuropathy peripheral def x x x x x x x x x
Pharyngitis def x
Respiratory disorder def x x x x x x x x x
Micturition disorder def
Urinary tract disorder def x x x x x x x x x
Visual impairment def x
Hypouricaemia x x x x x x x
Stools watery def
Osteoarthropathy def
Dysphasia def
Unspecified disorder of autonomic nervous system def x x x x x x x x x
Indication Labels
Abdominal bloating def x x x
Abdominal distress x
Affective disorder def x x x
Agitation def x x x x x x x x x
Agoraphobia def x
Anger def x x x
Anxiety def x x x
Bradypsychic response x x x x x x x x x
Breast tenderness x x x
Cerebration impaired def x x x x x x x x x
Chest pain def x
Chills def x
Choking def x
Compulsions def x
Decreased interest x x x x x x x x x
Depersonalisation def x
Depressed mood def x x x
Depressive disorder def x x x x x x x x x
Depressive episode x x x x x x x x x
Derealisation def x
Discomfort def x
Dizziness def x
Dysphoria x x x x x x x x x
Dyspnoea def x
Fatigue def x x x x x x x x x
Fear x
Fear of death x
Feeling guilty def x x x x x x x x x
Flushing def x
Headache def x x x
Heart pounding x
Hot flush def x
Irritability def x x x
Lightheadedness x
Major depression def x x x x x x x x x
Major depressive disorder, single episode x x x x x x x x x
Myalgia def x x x
Nausea def x
Numbness def x
Obsessive rumination x
Obsessive-compulsive disorder def x
Pain def x x x x
Palpitations def x
Panic attack def x
Panic disorder def x
Panic reaction def x
Paraesthesia def x
Premenstrual dysphoric disorder x x x
Suicidal ideation def x x x x x x x x x
Suicide def x x x x x x x x x
Suicide attempt def x x x x x x x x x
Sweating def x
Tenderness def x x x
Tension def x x x
Tingling sensation def x
Trembling x
Weight increased def x x x
Worry def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N06AB06

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. SERTRALINE (SERTRALINE HYDROCHLORIDE) / RIVA-SERTRALINE 100 : 10 side effects (Health Canada)
  2. SERTRALINE : 32 side effects (FDA XML label)
  3. SERTRALINE : 221 side effects (FDA XML label)
  4. SERTRALINE HYDROCHLORIDE / ZOLOFT : 249 side effects (Drugs@FDA)
  5. SERTRALINE : 255 side effects (FDA XML label)
  6. SERTRALINE : 260 side effects (FDA XML label)
  7. SERTRALINE : 260 side effects (FDA XML label)
  8. SERTRALINE : 260 side effects (FDA XML label)
  9. SERTRALINE : 260 side effects (FDA XML label)
  10. SERTRALINE : 262 side effects (FDA XML label)