Treprostinil (treprostinil sodium)

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3
Pain def postmarketing, 13% - 85% 5% - 27% x x x
Infusion site reaction 83% 27% x x
Cough def 53.9% 29.2% x x
Headache def 27% - 40.9% 22.5% - 23% x x x
Throat irritation 25.2% 14.2% x
Pharyngolaryngeal pain def 25.2% 14.2% x
Diarrhoea def 25% 16% x x x
Nausea def 19.1% - 22% 10.8% - 18% x x x
Flushing def 14.8% x
Rash def postmarketing, 14% 11% x x
Pain in jaw 13% 5% x x
Vasodilation def 11% 5% x x
Dizziness def 9% 8% x x x
Oedema def 9% 3% x x
Pruritus def 8% 6% x x
Syncope def 6.09% x x
Hypotension def 4% 2% x x
Cellulitis def postmarketing x x
Thrombocytopenia def postmarketing x x
Thrombophlebitis def postmarketing x x
Bone pain def postmarketing x x x
Abdominal pain def x
Anaemia def x
Anorexia def x
Anxiety def x
Arthralgia def x
Asthenia def x
Back pain def x
Bronchitis def x
Neck pain def x
Chest pain def x x
Dehydration def x
Dyspepsia def x
Dyspnoea def x x
Ecchymosis def x
Embolism def x
Epistaxis def x x
Fatigue def x x
Body temperature increased def x
Gout def x
Cardiac failure def x x
Cardiac failure congestive def x
Haematoma def x x
Haematuria def x
Haemoptysis def x x
Haemorrhage def x x x
Pulmonary hypertension def x
Hypokalaemia def x
Influenza def x
Cramps of lower extremities x
Melaena def x
Cramp muscle def x
Nervousness def x
Pain in extremity def x
Pallor def x x
Palpitations def x
Paraesthesia def x x
Pharyngitis def x
Pneumonia def x
Pseudomonas infection def x
Pulmonary embolism def x
Rhinitis def x
Sinusitis def x
Swelling def x x
Tachycardia def x
Erythema def x x
Urinary tract infection def x
Viral infection def x
Vomiting def x
Wheezing def x
Oedema peripheral def x
Pseudomonal sepsis x
Malaise def x
Myalgia def x
Hypoxia def x
Disease progression def x
Sepsis def x
Rectal haemorrhage def x
Clot blood def x
Induration def x x
Bradycardia def x
Swollen arm x x
Blood culture positive x
Insomnia def x
Indication Labels
Connective tissue disorder def x x
Hypertension def x x x
Infection def x x
Primary pulmonary hypertension x x x
Prolonged menses x
Pulmonary arterial hypertension x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: B01AC21

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. treprostinil : 16 side effects (FDA XML label)
  2. treprostinil : 28 side effects (FDA XML label)
  3. TREPROSTINIL (TREPROSTINIL SODIUM) / REMODULIN : 79 side effects (Health Canada)