Side effects and indications
Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.)
Information about indications was extracted from the indications and usage sections of the labels.
Show MedDRA Preferred Terms
|
Side effect
|
Data for drug
|
Placebo
|
Labels
(show all 48)
|
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
|
Rhinitis def
|
postmarketing — 15% - 23%
|
15%
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Asthenia def
|
postmarketing — 4% - 21%
|
4% - 11%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Diarrhoea def
|
postmarketing — 2% - 18%
|
4% - 13%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anorexia def
|
postmarketing, 1% - 17%
|
1% - 10%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Somnolence def
|
postmarketing, 2% - 17%
|
2% - 7%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Nervousness def
|
postmarketing — 3% - 15%
|
3% - 15%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tremor def
|
postmarketing — 1% - 13%
|
1% - 3%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Influenza def
|
postmarketing — 3% - 12%
|
3% - 7%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Dry mouth def
|
postmarketing — 3% - 12%
|
3% - 8%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Libido decreased def
|
postmarketing — 1% - 11%
|
1% - 2%
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Pharyngitis def
|
postmarketing, 3% - 11%
|
3% - 9%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Yawning def
|
postmarketing — 0.5% - 11%
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Dyspepsia def
|
postmarketing — 2% - 10%
|
2% - 6%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Infection def
|
postmarketing — 0% - 7%
|
3%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Erectile dysfunction def
|
postmarketing — 1% - 7%
|
|
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
|
Abnormal ejaculation
|
postmarketing — 1% - 7%
|
1%
|
|
x
|
x
|
|
|
|
x
|
|
x
|
x
|
|
Abdominal pain def
|
postmarketing — 5% - 6%
|
5%
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Rash def
|
postmarketing — 2% - 6%
|
2% - 4%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sinusitis def
|
postmarketing, 1% - 6%
|
2% - 4%
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Thinking abnormal
|
postmarketing, 0% - 6%
|
0% - 2%
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Amnesia def
|
infrequent, frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Arthralgia def
|
rare, frequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Back pain def
|
postmarketing, frequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Bronchitis def
|
frequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Confusional state def
|
rare — frequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Constipation def
|
postmarketing — 3% - 5%
|
3% - 4%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Drowsiness def
|
frequent
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Dysgeusia def
|
frequent
|
|
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Dysmenorrhoea def
|
postmarketing, frequent
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
|
Dysuria def
|
infrequent, frequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Ear pain def
|
infrequent, frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Flushing def
|
infrequent, frequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Gastritis def
|
infrequent, frequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemorrhage def
|
rare — frequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertension def
|
rare — frequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypoaesthesia def
|
infrequent, frequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Hypoglycaemia def
|
rare — frequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
Lethargy def
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Night sweats def
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Nightmare def
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Pruritus def
|
postmarketing — 2% - 3%
|
2%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Skin ulcer def
|
infrequent, frequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Tinnitus def
|
infrequent, frequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Ulcer def
|
rare — frequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pollakiuria def
|
frequent, 1% - 2%
|
1%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Urinary tract infection def
|
frequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Vasodilation def
|
postmarketing, 1% - 5%
|
1% - 2%
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Vertigo def
|
infrequent, frequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Visual impairment def
|
postmarketing — 1% - 3%
|
1%
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Weight decreased def
|
postmarketing — 1% - 3%
|
1%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Mood swings
|
infrequent, frequent
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Urinary hesitation
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Muscle twitching def
|
infrequent, frequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Increased appetite
|
frequent
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Anorgasmia def
|
infrequent, frequent
|
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Ejaculation delayed
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Abnormal dreams
|
postmarketing — 1% - 5%
|
1% - 3%
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Ejaculation disorder def
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Vision blurred def
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Initial insomnia
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Middle insomnia
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Sexual dysfunction
|
frequent
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
|
Sweating increased
|
frequent
|
|
|
|
|
x
|
|
|
x
|
x
|
|
|
|
Sleep disorder def
|
frequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Muscle tightness
|
frequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Body temperature increased def
|
postmarketing — 1% - 3%
|
1% - 2%
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Flatulence def
|
postmarketing, 2% - 3%
|
2%
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Albuminuria def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Alopecia def
|
infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Amblyopia def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Amenorrhoea def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Anaemia def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Angina pectoris def
|
infrequent
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Arrhythmia def
|
rare — infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Arthritis def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Asthma def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Ataxia def
|
infrequent
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Atrial fibrillation def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Breast feeding def
|
infrequent
|
|
|
|
|
|
|
x
|
|
x
|
x
|
|
|
Bruxism def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Bundle branch block def
|
rare, infrequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Bursitis def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Neck pain def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Cholelithiasis def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Colitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Conjunctivitis def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Convulsion def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Cystitis def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Cyst def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Dysphagia def
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dehydration def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Delirium def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Delusion def
|
rare, infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Depersonalisation def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Dermatitis def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dermatitis exfoliative def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Dermatitis contact def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Diplopia def
|
rare, infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Diverticulitis def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Dysarthria def
|
rare, infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Ecchymosis def
|
rare, infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eczema def
|
rare, infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Oedema def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Epistaxis def
|
infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eructation def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oesophageal disorder def
|
rare, infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Oesophageal stenosis def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Oesophagitis def
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Extrapyramidal disorder def
|
rare — infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Fibrocystic breast disease def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
|
x
|
|
Gastroenteritis def
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Gingival bleeding def
|
infrequent
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Gingivitis def
|
infrequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Glaucoma def
|
rare — infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Glossitis def
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gout def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hallucination def
|
postmarketing, infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Cardiac failure def
|
infrequent
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Cardiac failure congestive def
|
infrequent
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Haematuria def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Herpes NOS def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Herpes simplex def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Hiccups def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hostility def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hypercholesterolaemia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperlipidaemia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertensive crisis
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hypertriglyceridaemia def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hypertrophy def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperventilation def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hypokalaemia def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypotension def
|
postmarketing, infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Orthostatic hypotension def
|
postmarketing, infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Hypothyroidism def
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Incontinence def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Libido increased def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Infarction def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Irritable bowel syndrome def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Nephropathy def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Cramps of lower extremities
|
infrequent
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Leukopenia def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Leukorrhea def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Macular degeneration def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Breast pain def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
Melaena def
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Menopause def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Menorrhagia def
|
infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Metrorrhagia def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
Cramp muscle def
|
infrequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Hypertonia def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
|
x
|
x
|
|
Muscle rigidity def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Mydriasis def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Myocardial infarction def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Myoclonus def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Neurosis def
|
infrequent
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Nocturia def
|
infrequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Oliguria def
|
rare, infrequent
|
|
|
|
|
x
|
|
x
|
|
x
|
x
|
x
|
|
Orgasm abnormal def
|
infrequent
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
|
Ovarian disorder def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Pelvic pain def
|
infrequent
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Personality disorder def
|
rare, infrequent
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Phlebitis def
|
rare, infrequent
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Pneumonia def
|
rare — infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Polyuria def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Prurigo def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Psychotic disorder def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Retinal detachment def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Salivation def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Salivary hypersecretion def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastric disorder def
|
rare, infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastric ulcer def
|
rare, infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Stomatitis def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Aphthous stomatitis def
|
infrequent
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Swelling def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Syncope def
|
postmarketing, infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Tachycardia def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tenosynovitis def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Thirst def
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Thrombocytopenia def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Erythema def
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urinary incontinence def
|
infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
x
|
|
Urticaria def
|
postmarketing, infrequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Vaginal inflammation def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Vascular headache def
|
infrequent
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Urinary retention def
|
postmarketing, infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Encephalopathy def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Fever chills
|
infrequent
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Micturition urgency def
|
infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Bundle branch block right def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Apathy def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Photopsia
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Photophobia def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Oedema peripheral def
|
infrequent
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatic function abnormal
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Sicca syndrome def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Mouth ulceration def
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Migraine def
|
infrequent
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Neck stiffness
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Buccoglossal syndrome
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
|
x
|
x
|
|
CNS depression NOS
|
infrequent
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Creatinine increased def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Generalised oedema
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tongue oedema
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperchlorhydria
|
rare, infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Liver function test abnormal
|
infrequent
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Manic psychosis
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Muscular weakness def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Bone pain def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Eye pain def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Paranoid reaction
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Vesiculobullous rash
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Skin discolouration def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Dry skin def
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Photosensitivity reaction def
|
rare, infrequent
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Hangover
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Malaise def
|
infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Cardiac fibrillation
|
rare — infrequent
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Cold sweat
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Abdominal pain lower
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Disorientation
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Pressure of speech
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Rash erythematous
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Euphoric mood def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Pain in jaw
|
infrequent
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Dyslipidaemia def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Peripheral coldness
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Dry eye
|
infrequent
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Mania def
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
|
Photosensitivity def
|
rare, infrequent
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Akathisia def
|
infrequent
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Gastric irritation
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Rash maculo-papular def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Increased tendency to bruise
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hyperkinesia def
|
infrequent
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rigors
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Lymphadenopathy def
|
infrequent
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Coordination abnormal
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Impaired gastric emptying
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Detachment psychological
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Face oedema def
|
infrequent
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Visual disturbance
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Feeling jittery
|
postmarketing, infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Urine flow decreased
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Gait disturbance def
|
infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Blood cholesterol increased
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Acne def
|
infrequent
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Maculopathy
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Coldness
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Completed suicide
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Arterial disorder def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hypertensive
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hyperkeratosis def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Sluggishness
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Urine output
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Blood in stool
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Feeling abnormal
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Weakness def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Coronary artery disease def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Breast enlargement
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hepatic steatosis def
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Feeling hot
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Vaginal haemorrhage def
|
rare, infrequent
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Loss of libido
|
infrequent
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Acute abdomen def
|
rare
|
|
|
x
|
x
|
|
x
|
|
|
x
|
x
|
x
|
|
Acidosis def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Ageusia def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Aggression def
|
rare
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Alveolitis allergic def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Anaphylactic shock def
|
postmarketing
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Aplastic anaemia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemolytic anaemia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypochromic anaemia def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Angioedema def
|
postmarketing, rare
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Apnoea def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Rheumatoid arthritis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Atelectasis def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Atrioventricular block def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Blepharitis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Encephalopathy chronic def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Bronchospasm def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Candidiasis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Carpal tunnel syndrome def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Cerebral artery embolism
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Cholecystitis def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Chondrodystrophy def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Coma def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Cough def
|
postmarketing, rare
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Deafness def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Fungal skin infection def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Diabetes mellitus def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Diabetic ketoacidosis def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Duodenal ulcer def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyskinesia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Effusion def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Embolism def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Enteritis def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Epididymitis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Erythema multiforme def
|
postmarketing, rare
|
|
|
x
|
x
|
|
|
|
x
|
|
x
|
x
|
|
Erythema nodosum def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Exophthalmos def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Eye haemorrhage def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Liver fatty def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Faecal incontinence def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Fibrosis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Pathological fracture def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Furunculosis def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Gastrointestinal disorder def
|
postmarketing
|
|
|
|
|
x
|
|
|
x
|
x
|
|
|
|
Gastrointestinal haemorrhage def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Glycosuria def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Goitre def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Gynaecomastia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Cardiac arrest def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Block heart def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Haematemesis def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Blood disorder def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Haemoptysis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hepatitis def
|
rare, postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatomegaly def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Herpes zoster def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hirsutism def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hydrocephalus def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Hyperaemia def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Hyperaesthesia def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Hyperglycaemia def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Hyperkalaemia def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Hyperprolactinaemia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypersensitivity def
|
rare
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Pulmonary hypertension def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
|
Hyperthyroidism def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Salivary gland enlargement
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypocalcaemia def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Hypomenorrhoea
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Hyponatraemia def
|
postmarketing, rare
|
|
|
|
|
x
|
|
|
x
|
|
|
|
|
Body temperature decreased def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Hysteria def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Inappropriate antidiuretic hormone secretion def
|
postmarketing, rare
|
|
|
|
|
x
|
|
|
x
|
x
|
|
|
|
Intestinal obstruction def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Iritis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
Ischaemia def
|
rare
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Jaundice def
|
postmarketing, rare
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Jaundice cholestatic def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Arthropathy def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Calculus of kidney def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Laryngeal oedema def
|
rare
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Leiomyoma def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Leukocytosis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Systemic lupus erythematosus def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Lymphoedema def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Lymphocytosis def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Movement disorder def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myopathy def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Myositis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Necrosis def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Neuritis def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Neuroleptic malignant syndrome def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nystagmus def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Obstruction def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Optic neuritis def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
|
Orchitis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Osteomyelitis def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Osteonecrosis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Osteoporosis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Pallor def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Pancreatitis def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pancytopenia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Peptic ulcer def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Petechiae def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pleural disorder def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Pleural effusion def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Pneumothorax def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Priapism def
|
rare
|
|
x
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Ptosis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Psoriasis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Pulmonary oedema def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Pulmonary embolism def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Emphysema def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Pulmonary fibrosis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Purpura def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
x
|
x
|
|
Pyelonephritis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Pyuria def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Hyperacusis def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Renal failure def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Retinal haemorrhage def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Salpingitis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Scleritis def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Scotoma def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Seborrhoeic dermatitis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Serum sickness def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Shock def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Muscle spasms def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Strabismus def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Stridor def
|
rare
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
|
Cerebrovascular accident def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Thrombophlebitis def
|
rare
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Thrombosis def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Torsade de pointes def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
|
Torticollis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Deficiency anaemia
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urethritis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Uterine leiomyoma def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Uterine haemorrhage def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Angiopathy def
|
rare
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Vasculitis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Ventricular fibrillation def
|
rare
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Ventricular tachycardia def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
|
Peripheral vascular disorder def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Hepatic failure def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Ventricular arrhythmia def
|
rare
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Atrioventricular block first degree def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Vasospasm def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Stupor def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Rash pustular def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Footdrop
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Breast engorgement def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Cataract def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
x
|
x
|
|
Alcohol intolerance def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Bleeding time prolonged
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Blood urea increased
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Corneal lesion
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Cough decreased
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Creatine phosphokinase increased def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Diarrhoea haemorrhagic
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
x
|
|
Tongue discolouration
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Electroencephalogram abnormal
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Necrolysis epidermal
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Red blood cell sedimentation rate increased
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Ventricular extrasystoles def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Hemorrhage of colon def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Muscle haemorrhage
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Bleeding vaginal def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Skin hypertrophy
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Liver fatty deposition
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Liver tenderness
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Biliary colic def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Urethral pain def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Circumoral paresthesia
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Phosphatase alkaline increased
|
rare, postmarketing
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Purpuric rash
|
rare
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hyporeflexia
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hyperreflexia
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Aspartate aminotransferase increased def
|
postmarketing
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Alanine aminotransferase increased def
|
rare, postmarketing
|
|
|
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
Oesophageal ulcer def
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Uterine fibroids enlarged
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Uterine spasm
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Drug withdrawal syndrome def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Iron deficiency anaemia def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Antisocial behaviour def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Memory impairment def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
Galactorrhoea
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Iron deficiency
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Protrusion tongue
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Violent
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypoxia def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Rectal haemorrhage def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Blood bilirubin increased def
|
postmarketing
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Ulcer haemorrhage
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Dysplasia def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Extrasystoles def
|
rare
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Gastric ulcer haemorrhage
|
rare
|
|
|
x
|
x
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Enlargement abdomen def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Dystonia def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Hypoventilation def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Bradycardia def
|
rare
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Urolithiasis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Respiratory distress def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Paralysis def
|
rare
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Alveolitis
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Renal pain
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Cough increased
|
postmarketing
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Hyperuricaemia def
|
rare
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
Thrombocytosis def
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Thrombocytopenic purpura def
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
x
|
x
|
|
Cerebral ischaemia def
|
rare
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Myasthenia def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Malignant syndrome NOS
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Death
|
rare
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspareunia def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Parosmia def
|
rare
|
|
|
|
|
|
|
x
|
|
x
|
x
|
x
|
|
Eosinophilic pneumonia
|
rare, postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
|
Leukocytoclastic vasculitis def
|
rare
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Mental disorder def
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
|
Breast disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Connective tissue disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Grand mal convulsion def
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Eye disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Cardiac disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hyperhidrosis def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Mediastinal disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Menstrual disorder def
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
Nasopharyngitis def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Nervous system disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Pain in extremity def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Polymenorrhoea
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Postmenopausal haemorrhage
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Respiratory tract infection def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Seizures def
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Upper respiratory tract infection def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Micturition disorder def
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Urinary tract disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Decreased appetite
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Abdominal pain upper
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Menometrorrhagia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hypomania def
|
|
|
|
x
|
x
|
|
x
|
|
|
|
x
|
x
|
|
Ejaculation failure
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Tonic-clonic seizures def
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Balance disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drug interaction def
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Dissecting aortic aneurysm, thoracic
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Diabetic peripheral neuropathy
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Infestation NOS
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Genital haemorrhage
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mental status changes
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Pharyngolaryngeal pain def
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Female sexual dysfunction
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
|
Unspecified disorder of autonomic nervous system def
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Indication
|
Labels
|
|
Abdominal bloating def
|
|
|
|
|
|
x
|
|
|
|
|
|
Abdominal distress
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Affective disorder def
|
|
|
|
|
|
x
|
|
|
|
|
|
Agitation def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Agoraphobia def
|
x
|
x
|
x
|
|
x
|
|
|
|
x
|
x
|
|
Anger def
|
|
|
|
|
|
x
|
|
|
|
|
|
Anxiety def
|
|
|
|
|
|
x
|
|
|
|
|
|
Binge eating def
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Bipolar I disorder
|
|
|
x
|
|
|
|
|
|
|
|
|
Bradypsychic response
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Breast tenderness
|
|
|
|
|
|
x
|
|
|
|
|
|
Bulimia def
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Bulimia nervosa def
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Cerebration impaired def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Chest pain def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Chills def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Choking def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Compulsions def
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Decreased interest
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
|
Depressed mood def
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
|
Depressive disorder def
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
Depressive episode
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Diabetic peripheral neuropathic pain
|
|
|
|
x
|
|
|
|
|
|
|
|
Discomfort def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Dizziness def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Dysphoria
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Dyspnoea def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Elderly def
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Fatigue def
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
|
Fear
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Fear of death
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Feeling guilty def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Headache def
|
|
|
|
|
|
x
|
|
|
|
|
|
Heart pounding
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Hot flush def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Hypersomnia def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Insomnia def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Irritability def
|
|
|
|
|
|
x
|
|
|
|
|
|
Lightheadedness
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Major depression def
|
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
|
Major depressive disorder, single episode
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Myalgia def
|
|
|
|
|
|
x
|
|
|
|
|
|
Nausea def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Neuralgia def
|
|
|
|
x
|
|
|
|
|
|
|
|
Neuropathy def
|
|
|
|
x
|
|
|
|
|
|
|
|
Neuropathy peripheral def
|
|
|
|
x
|
|
|
|
|
|
|
|
Numbness def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Obsessive rumination
|
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Obsessive-compulsive disorder def
|
x
|
x
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
|
Pain def
|
x
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
|
Palpitations def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Panic attack def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Panic disorder def
|
x
|
x
|
x
|
|
x
|
|
|
|
x
|
x
|
|
Panic reaction def
|
x
|
x
|
x
|
|
x
|
|
|
|
x
|
x
|
|
Paraesthesia def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Premenstrual dysphoric disorder
|
|
|
|
|
|
x
|
|
|
|
|
|
Purging
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Sickness
|
|
|
|
|
|
|
x
|
x
|
|
|
|
Suicidal ideation def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Suicide def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Suicide attempt def
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
|
Sweating def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Tenderness def
|
|
|
|
|
|
x
|
|
|
|
|
|
Tension def
|
|
|
|
|
|
x
|
|
|
|
|
|
Tingling sensation def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Trembling
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Vomiting def
|
x
|
x
|
x
|
|
x
|
|
|
|
x
|
x
|
|
Weight increased def
|
|
|
|
|
|
x
|
|
|
|
|
|
Worry def
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
|
Information
More information: STITCH, PubChem and possibly Wikipedia or Medpedia
ATC Code:
N06AB03
Legend
Color scheme:
standard – alternative
|
100%
|
|
|
|
75%
|
|
|
|
50%
|
|
|
|
10%
|
|
|
|
frequent (1% to 100%)
|
|
|
|
infrequent (0.1% to 1%)
|
|
|
|
rare (<0.1%)
|
|
|
|
postmarketing
|
|
|
|
0%
|
|
|
|
no frequency information
|
|
|
|
not found on label
|
|
|
Labels
Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.
- FLUOXETINE :
7 side effects
(FDA XML label)
- FLUOXETINE :
121 side effects
(FDA XML label)
- FLUOXETINE :
121 side effects
(FDA XML label)
- FLUOXETINE HYDROCHLORIDE / PROZAC WEEKLY :
188 side effects
(Drugs@FDA)
- fluoxetine hydrochloride / Prozac :
204 side effects
(FDA MedWatch)
- fluoxetine hydrochloride / Sarafem :
271 side effects
(FDA MedWatch)
- FLUOXETINE (FLUOXETINE HYDROCHLORIDE) / RATIO-FLUOXETINE :
303 side effects
(Health Canada)
- FLUOXETINE (FLUOXETINE HYDROCHLORIDE) / SANDOZ FLUOXETINE :
323 side effects
(Health Canada)
- FLUOXETINE :
333 side effects
(FDA XML label)
- Fluoxetine :
335 side effects
(FDA XML label)
|