Doxorubicin hydrochloride

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Sort by: related terms – frequency

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Alopecia def 6.7% — 95.5% x x x x x x x x x x x x x x x x x x x x x
Vomiting def 6.4% — 92.4% x x x x x x x x x x x x x x x x x x x x x
Nausea def 6.4% — 92.4% x x x x x x x x x x x x x x x x x x x x x
Amenorrhea def 0% — 71.8% x x x x x x x x x x x
Menopausal hot flushes def 0% — 69.1% x x x x x x x x x x x
Diarrhea def 0% — 50.7% x x x x x x x x x x x x x x x x x x x x x
Keratitis def 0% — 38.4% x x x x x x x x x x x x
Conjunctivitis def 0% — 38.4% x x x x x x x x x x x x x x x x x x x x
Asthenia def 6.49% — 33% x x x x x x x x x x x x x x x
Infection def 0% — 25.9% x x x x x x x x x x x x x x x x x x x x
Constipation def 12.7% x x x x x x x x
Anorexia def 0% — 11.9% x x x x x x x x x x x x x x x x x x x x x
Hypochromic anemia def 5.19%, 9.79% x x x x x x
Abdominal Pain def 8% x x x x x x x x x x x x x x x
Paresthesia def 7.8% x x x x x x x
Stomatitis def 5.19% — 6.81% x x x x x x x x x x x x x x x x x x x x
Oral candidiasis def 1.3% — 5.53% x x x x x x x
Dry skin 5.5% x x x x x x x
Pharyngitis def 5.5% x x x x x x x x
Hyperpigmentation def postmarketing x x x x x x x x x x x x x x
Pulmonary Embolism def postmarketing x x x x
Toxic Epidermal Necrolysis def postmarketing x x
Erythema Multiforme def postmarketing x x x x x x x
Stevens-Johnson Syndrome def postmarketing x x x
Dehydration def postmarketing x x x x x x x x x x x x x x x x x x x
anaphylaxis def postmarketing x x x x x x x x x x x x x x
Photosensitivity def postmarketing x x x x x x x x x x x x x
Venous Thrombosis def postmarketing x x
Phlebitis def postmarketing x x x x x x x x x
Thrombophlebitis def postmarketing x x x x x x x x x x x x
Spasm def postmarketing x x
Urticaria def postmarketing x x x x x x x x x x x x x x x x x x
Shock def postmarketing x x x x x x x x x x x x x x x
Mediastinal Diseases def postmarketing x x
Connective Tissue Diseases def postmarketing x x
Herpes NOS x x x
Lymphangitis x x x x x x x
hypermagnesemia x x x x x
Abnormal pigmentation x x x
Allergy to penicillin x x x x x x x
Toxoplasmosis def x x x x x x x
Kaposi Sarcoma def x x x
Nonspecific ulcerative proctitis x x x x x x x
Cholangitis, Sclerosing def x x x x x x x
Hypochloremia def x x x x x
Menopause, Premature def x x x
Lymphoblastic Leukemia def x x x x x
[D]Retrosternal chest pain x x x x x x
Ulcer of esophagus x x x x x x x
Candidiasis, Cutaneous def x x x x x x x
Balanitis def x x x x x x x
Leukoplakia, Oral def x x x x x x x
Fecal Impaction def x x x x x x x
Retinitis def x x x x x x x
mastitis def x x x x x
Hypernatremia def x x x x x x x
hypothermia, natural def x x x x x x x
Septic Shock def x x x x
Septicemia def x x x x x x
Onycholysis x x x x x
Tachycardia, Sinus def x x x x x
Infection by Cryptococcus neoformans def x x x x x x x x
Pneumothorax def x x x x x x x
Cachexia def x x x x x x x
Polyneuropathy def x x x
Proctitis def x x x x x
[D]Tenesmus x x x x x x x
Dysphonia x x x
Liver function tests abnormal finding x x x
Myositis def x x x x x x x
[D]Urgency of micturition x x x
Nycturia x x x x x
Atrial Premature Complexes def x x x
Bundle-Branch Block def x x x x x x x x x x
Abscess def x x x x x x x
Periodontal Abscess def x x x x x
Deep thrombophlebitis x x x x
Hemiplegia def x x x x x x
Scotoma def x x x x x x
Seborrheic dermatitis def x x x
Dysesthesia x x x
Hyperesthesia def x x x x x
Hypopigmentation def x x x
Folliculitis def x x x
Furunculosis def x x x x x x x x
Skin nodule x x x x x
Erythema Nodosum def x x x x x x x
Ureteral obstruction def x x x
Ascites def x x x x x x
Hydronephrosis def x x x x x
Lymphedema def x x x x x x x
Cardiomegaly def x x x x x x x
[D]Lactic acid dehydrogenase raised x x x
[D]Alkaline phosphatase raised x x x
Aspartate aminotransferase increased def x x x
Hypophosphatemia def x x x x x x x
Hypomagnesemia def x x x x x x x
Hypercalcemia def x x x x x x x x
Hypocalcemia result def x x x x x x
Hyperphosphatemia x x x
Lymphopenia def x x x
Myeloid Leukemia def x x x
Dysmyelopoietic Syndromes def x x x
Pericardial effusion def x x x x x x x x
Myocarditis def x x x x
Pericarditis def x x x x
Sialorrhea def x x x x x
Hypoxia def x x x x
Drug abuse def x x x
Optic Neuritis def x x x x x x x x
Neuritis def x x x x x x x
Candidiasis of vagina x x x x x x x
Candidiasis def x x x x x x x x
Vaginitis def x x x x x x
Colitis def x x x x x x x x x
Constitutional Symptom x x x
Blepharitis def x x x x
Dryness of eye x x x x
Dermatomycoses def x x x x x x
Nail Diseases def x x x
Albuminuria def x x x x x x x
hyperkalemia def x x x x x x x
comatose def x x x x
Nystagmus def x x x
Amblyopia def x x x x x
Glossitis def x x x x x x x
Dysarthria def x x x
Mood swings x x x x x x x
Diplopia def x x x
Gait abnormality x x x x
Ataxia def x x x x x
Eye pain x x x x x x x
Bone pain x x x x x x x
Gingivitis def x x x x x x x
Gingival Hemorrhage def x x x x x
Hematemesis def x x x
Mastodynia x x x x x
Neck Pain def x x x x x
Earache def x x x
Migraine Disorders def x x x x x x x
Bleeding of vagina x x x x x x
Enlargement of lymph nodes def x x x x x x x
Rectal hemorrhage def x x x x
Neuralgia def x x x x
Laryngitis def x x x x x
Otitis Media def x x x x x x x
Hyperuricemia def x x x x x x x x x x x
Hyperlipidemia def x x x x x x x
Aphthous Stomatitis def x x x x x x x
Oral Ulcer def x x x x x x x x
Skin Ulcer def x x x x x x x
Psoriasis def x x x x x x x
Glycosuria def x x x x x x x
Contact Dermatitis def x x x x x
Gastric ulcer def x x x
Esophagitis def x x x x x x x x x x x x x x x x x x x x
Cellulitis def x x x x x x x x x x x x
Herpes zoster disease def x x x x x x x x x
Herpes Simplex Infections def x x x x x x x x
Acne def x x x x x x x x
Blind Vision def x x x x x x x
Delirium def x x x x x x x
Hiccup def x x x x x x
Pathological fracture def x x x
Ventricular Premature Complexes def x x x
Heart Arrest def x x x x x x x
Bradycardia def x x x x x x
Pleural effusion disorder def x x x x x x x
Hemoptysis def x x x
Petechiae x x x x x x x
Ecchymosis def x x x x x x
Cerebrovascular accident def x x x
Hypotension, Orthostatic def x x x x x
Muscle Weakness def x x x
Bulla def x x x x x x x
Dermatitis, Exfoliative def x x x x x x x x
Pancytopenia def x x x
Eosinophilia def x x x x x x x
hypoglycemia def x x x x x x x
Hyponatremia def x x x x x x x
Pancreatitis def x x x x x x x
Hypokalemia def x x x x x x x x x
Diabetes Mellitus def x x x x x x x
Hyperglycemia def x x x x x x x
[D]Peripheral edema x x x x x x x
Urinary Incontinence def x x x
Angina Pectoris def x x x x x
Urinary tract infection def x x x x x x x x
Bronchitis x x x x x x x
Sinusitis def x x x x x x x x
Epistaxis def x x x x x x x x
Deglutition Disorders def x x x x x x x x
Ulcer def x x x x x x x x
Voice Disorders def x x x x x
Gastrointestinal Hemorrhage def x x x x x x x
Melena def x x x x x x
Hematuria def x x x x x x x x
Disturbance in thinking x x x x x x
Purpura def x x x x
Body Weight decreased def x x x x x x x x x x x
Weight Gain def x x x x x x x x x x
Agitation def x x x x
Frequency of micturition def x x x
Pelvic Pain def x x x x x x
[X]Painful micturition, unspecified def x x x x x x x
Hypertensive disease def x x x x x
Tinnitus def x x x x x x x
Vertigo def x x x x x x x
Eructation def x x x x x x
Flatulence def x x x x x x x
Dyspepsia def x x x x x x x x x
Sleeplessness x x x x x x x x
Pneumonia def x x x x x x x x x
Influenza def x x x x x x x
Virus Diseases def x x x x
Rhinitis def x x x x x x x x
Myalgia def x x x x x x x x
Arthralgia def x x x x x x x
Hepatitis def x x x x x x x x
Hyperbilirubinemia def x x x x x x x x
Icterus def x x x x x x x x
Convulsions def x x x
Seizures def x x x x x x x x x x
Xerostomia def x x x x
Sweating def x x x x x x x
Palpitations def x x x x x x x x
cardiac arrhythmia def x x x x x x x x x x x x x
Nervousness x x x x x x
Agranulocytosis def x x x x
Gastritis def x x x x x x x
Dyspnea def x x x x x x x x x
Coughing def x x x x x x x x
Confusion def x x x x x x x
Visual impairment def x x x x x x x
Dyskinetic syndrome def x x x
Anxiety def x x x x x x x
Drowsiness x x x x x x x x x
Allergic Reaction x x x x x x x x
Peripheral Vascular Diseases def x x x
Paralysed def x x x
Paresis def x x x
Malaise def x x x x x x x x x x x x x x
Fatigue def x x x x x x x x x x
Dizziness def x x x x x x x x x
Edema def x x x x x x x
Kidney Failure, Acute def x x x x
Kidney Failure def x x x x x x x
Liver Failure def x x x x x x x
Lung diseases def x x x
Peripheral Neuropathy def x x x x
Neuropathy def x x x x x x x x
Laboratory test result abnormal x x x
Arthropathies NOS def x x x
Eczema def x x x
Dermatitis def x x x x
Indication Labels
Anemia def x x
Apnea def x x
Asthma def x x
Atrophy of testis x x
Back Pain def x x
Bladder Neoplasm def x x
Brain Neoplasms def x
Breast Carcinoma def x x x x x x x x x x x x x x x x
Bronchial Spasm def x x
Burning sensation x x
Carcinoma def x x x x x x
Carcinoma of bladder def x x x x x
Carcinoma of lung def x x
Carcinoma testes x
Cardiomyopathies def x x
Chest Pain def x x
Chills def x x
Congestive heart failure def x x
Cystitis def x x
Erythema def x x
Exanthema def x x
Fetal Death def x
Fever def x x
Flushing def x x
Headache def x x
Heart failure def x x
Hemorrhage def x x
HIV Infections def x x
Hypersensitivity def x x x
Hypotension def x x
leukemia def x
Leukemia, Lymphocytic, Acute def x x x x x
Leukemia, Myelocytic, Acute def x x x x x x x
Leukopenia def x x
Lymphoma def x x x x x x x x x x x
Malignant Neoplasms def x x x x
melanoma def x
Multiple Myeloma def x x
Neoplasms def x x x x x x x x x x x x x x x x x
Neuroblastoma x x x x x x
Neutropenia def x x
osteosarcoma def x x x x x x
Ovarian Carcinoma x x x x x x x x x x x
Pain def x x
Pancreatic Cancer x
Primary carcinoma of the liver cells def x
Prostate carcinoma def x
Pruritus def x x
Renal carcinoma def x
sarcoma def x x x x x x x x x
Shortness of Breath x x
Small cell carcinoma of lung def x x
Stomach Carcinoma def x x x x x x x x x
Swelling def x x
Syncope def x x
Systemic infection def x x
Tachycardia def x x
Thrombocytopenia def x x
Thyroid carcinoma def x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Codes: L01DB01, L01DB03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. DOXORUBICIN HYDROCHLORIDE / MYOCET : 39 side effects (Health Canada)
  2. doxorubicin HCl liposome injection / Doxil : 150 side effects (FDA MedWatch)
  3. doxorubicin HCl / Doxil : 171 side effects (FDA MedWatch)
  4. DOXORUBICIN HYDROCHLORIDE / DOXIL : 171 side effects (FDA CDER)
  5. DOXORUBICIN HYDROCHLORIDE / DOXIL : 169 side effects (FDA CDER)
  6. DOXORUBICIN HYDROCHLORIDE / CAELYX : 165 side effects (Health Canada)
  7. doxorubicin : 70 side effects (FDA XML label)
  8. Epirubicin : 33 side effects (BC Cancer)
  9. Doxorubicin : 22 side effects (BC Cancer)
  10. doxorubicin : 18 side effects (FDA XML label)
  11. DOXORUBICIN HYDROCHLORIDE / DOXORUBICIN HYDROCHLORIDE INJECTION : 32 side effects (Health Canada)
  12. DOXORUBICIN HYDROCHLORIDE / DOXORUBICIN HYDROCHLORIDE FOR INJECTION USP : 33 side effects (Health Canada)
  13. EPIRUBICIN HYDROCHLORIDE / PHARMORUBICIN PFS : 29 side effects (Health Canada)
  14. EPIRUBICIN HYDROCHLORIDE / EPIRUBICIN HYDROCHLORIDE FOR INJECTION : 29 side effects (Health Canada)
  15. epirubicin : 19 side effects (FDA XML label)
  16. EPIRUBICIN HYDROCHLORIDE / ELLENCE : 19 side effects (FDA CDER)
  17. EPIRUBICIN HYDROCHLORIDE / EPIRUBICIN HYDROCHLORIDE : 19 side effects (FDA CDER)
  18. epirubicin : 19 side effects (FDA XML label)
  19. DOXORUBICIN HYDROCHLORIDE / ADRIAMYCIN PFS : 25 side effects (FDA CDER)
  20. Doxorubicin : 26 side effects (FDA XML label)