Search results :

Doxorubicin

More information: STITCH, PubChem (stereo-specific compounds: 1, 2, 3) and possibly Wikipedia

ATC Codes: L01DB01, L01DB03

Side effects

Options: Show MedDRA Preferred Terms,   display only 20 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Neutropenia common — 1.6% - 95.8% x x x x x x x x x x x x x x x x x x x x x x x x x x x
Leukopenia uncommon — 1.5% - 98.1% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Alopecia common — 6.7% - 95.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Nausea postmarketing — 0% - 92.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Vomiting common — 0% - 92.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Fatigue 0% - 46% x x x x x x x x x x
Immunodeficiency very common x
Opportunistic infection very common x x x
Injection site reaction 2-20% x x x x x x x x x x x x x x x x
Mucosal inflammation postmarketing, 0% - 58.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Asthenia postmarketing — 0% - 51.5% x x x x x x x x x x x x x x x x x x x x x x x x
Anaemia uncommon — 0% - 72.2% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Neuropathy peripheral 1% - 45% x x x x x
Constipation very common, 0% - 31% x x x x x x x x x
Amenorrhoea 0% - 71.8% x x x x x x x x x x x x x x x x x x x x x x x
Skin discolouration common, 6.1% x x x x x x x
Pharyngitis common, 0% - 17.9% x x x x x x x x
Dry skin common, 5.5% - 5.9% x x x x x x x
Thrombocytopenia uncommon — 0% - 51.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Hot flush postmarketing, 0% - 69.1% x x x x x x x x x x x x x x x x x x x x x x x x x
Dyspepsia common, 0% - 14% x x x x x x x x
Somnolence common, 5.1% x x x x x x x x
Hypochromic anaemia common, 3.5% - 9.6% x x x x x
Anxiety common x x x x x
Arthralgia common x x x x
Back pain common, 0.9% - 11.7% x x x x x x x x
Cachexia common x x x x
Cardiovascular disorder common x x x x
Chest pain common x x x x x x x x
Dysphagia common x x x x x x x
Dermatitis exfoliative common x x x x x x x
Diarrhoea postmarketing — 0% - 50.7% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Dysgeusia common x x x x x x x
Dyspnoea common, 1% - 23.4% x x x x x x x x x x
Dysuria common x x x x x
Epistaxis common x x x x x x x x
Flatulence common x x x x
Gastritis common x x x x
Gingivitis common x x x x
Headache common, 0% - 14.9% x x x x x x x x
Hyperbilirubinaemia common x x x x x x
Hypertension common x x x
Hypotension common x x x x x x x x
Orthostatic hypotension common x x x
Cramps of lower extremities common x x x x
Breast pain common x x x x x
Hypertonia common x x x x
Musculoskeletal pain common x x x x
Nasopharyngitis common x x
Pain in extremity common x x
Paraesthesia common, 0% - 11.7% x x x x x x x x
Retinitis common x x x x x
Skin disorder common x x x x x
Skin ulcer common x x x x
Sweating common x x x x x
Upper respiratory tract infection common x x x x
Urinary tract infection common x x x x x x
Vaginal inflammation common x x x x
Dry mouth common x x x
Ventricular arrhythmia common x x x x x x x
Oedema peripheral common x x x x x
Mouth ulceration common x x x x x x x
Muscular weakness common x x x
Bone pain common x x x x x
Vesiculobullous rash common x x x x x x
Myalgia common x x x x x x
Blood creatinine increased common x x
Vision blurred common x x x x
Rash maculo-papular common x x x x x x
Neuropathy common, 0.6% - 9.2% x x x x
Musculoskeletal chest pain common x x
Metastases to liver common x
Cough increased common, 0% - 11.5% x x x x x x x
Serum creatinine increased common x x x
Ejection fraction decreased common x x
Cardiotoxicity uncommon — 18-65% x x
Insomnia common x x x x x x
Dizziness common, 0% - 10.2% x x x x x x x x x x
Mucous membrane disorder very common, 0% - 14.5% x x x x x x x
Herpes zoster common, 0% - 9% x x x x x x x x x
Oral candidiasis common, 0.8% - 5.6% x x x x x x x
Eye disorder 3% x x x x x x
Neuralgia 0% - 20% x x x
Oedema uncommon, common x x x x x x
Stomatitis postmarketing — 0% - 41.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Weight decreased common, 0% - 4% x x x x x x x x x x
Anorexia postmarketing — 0% - 21.7% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Laboratory test abnormal 0% - 5.8% x
Arrhythmia 0.5-3% x x x x x x x x x x x x
Infection postmarketing — 0% - 25.9% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Lethargy 0% - 72.7% x x x x x x x x x x x x x x x x
Red blood cell disorders 0% - 5% x x
Rash postmarketing — 0% - 28.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Febrile neutropenia 0% - 6.1% x x x x x x x x x x x x x x x x x x x x x x
Body temperature increased postmarketing — 0% - 30.6% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Scrotal erythema common, 1% x x
Sepsis postmarketing — 0.9% - 1.2% x x x x x x x x x x x x x x x x x x x x x x x x x
Abdominal pain postmarketing — 0% - 8.2% x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Shock postmarketing, 0.9% - 1% x x x x x x x x x x x x x x x x x x x x x x x x x x x
Neuritis uncommon, 0.8% - 8% x x x
Breast disorder 1% x x x x
Pain postmarketing — 1.2% - 7.4% x x x x x x x x x x x x x x x x x x x x x x x x x x
Amblyopia uncommon x x
Cardiac failure congestive uncommon x x x x x x x x x x x x x x x x x x
Nail disorder uncommon x x x x x
Palpitations uncommon x x x x x
Rhinitis uncommon x x x x x x
Anaphylactoid reaction uncommon x x x x
Enlargement abdomen uncommon x x x
Myelosuppression uncommon x x x x x x x x x x x x x x x x x x x x x x x x
Cardiomyopathy uncommon x x x x x x x x x x x x x
Ovarian cancer uncommon x
Herpes simplex common, 0% - 6% x x x x x x x
Myelodysplastic syndrome 0.3-0.6% x
Leukaemia 0% - 1-10% x x x x x x x x x x x x x x x
Venous thrombosis postmarketing, uncommon x x x
Venous thromboembolism postmarketing, uncommon x
Anaphylactic shock postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Neoplasm malignant postmarketing x
Coma postmarketing x x x x x
Conjunctivitis postmarketing — 0% - 38.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Connective tissue disorder postmarketing x x x x
Cyst postmarketing x x
Dehydration postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Toxic epidermal necrolysis very rare, postmarketing x x x x x
Erythema multiforme very rare, postmarketing x x x x x x
Oesophagitis postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Flushing postmarketing — 1% - 5% x x x x x x x x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder postmarketing x x x x x x x x x x x x
Haematochezia postmarketing x x
Blood disorder postmarketing x x
Haemorrhage postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Hypersensitivity postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Immune system disorder postmarketing x x x x x x x x x x
Keratitis postmarketing, 0% - 38.4% x x x x x x x x x x x x x x x x x x x x x x x x
Acute myeloid leukaemia postmarketing x x
Mediastinal disorder postmarketing x x x x x x x x x x x x x
Oral neoplasm postmarketing x x x
Neoplasm postmarketing x
Phlebitis postmarketing — 0.3% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Pneumonia postmarketing, common x x x x x x x x x x x x x x x x
Polyp postmarketing x x
Pruritus postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x
Pulmonary embolism postmarketing, uncommon x x x x x x x x x x x x x x
Convulsion postmarketing, uncommon x x x x x x x x x
Cardiogenic shock postmarketing x x
Muscle spasms postmarketing, common x x x x
Stevens-Johnson syndrome very rare, postmarketing x x x x x
Thromboembolism postmarketing x x x x x x x x x x x x x x x x x
Thrombophlebitis postmarketing, uncommon x x x x x x x x x x x x x x x x x x x x x x x x
Ulcer postmarketing x x x x x x x x x x x x x x x x x x x x x x x
Erythema postmarketing x x x x x x x x x x x x x x x x x x x x x
Urinary tract disorder postmarketing x x x x x x x x x x x
Urticaria postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Angiopathy postmarketing x x x x x x x x x x x x
Weight increased postmarketing x x x x x x x x
Chills postmarketing — 0.3% - 6.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Burning sensation postmarketing x x x x x x x x x x x x x x x x x x x
Aspartate aminotransferase increased postmarketing — common x x x x x
Alanine aminotransferase increased postmarketing, common x x x x x x
Malnutrition postmarketing x x x x x x x x x x x x x x x
Skin hyperpigmentation postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x x x x x x x x
Fatal outcomes postmarketing x x
Malaise postmarketing — 0.4% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Peripheral motor neuropathy postmarketing x x
Acral erythema postmarketing x x x x x x x
Caecitis postmarketing x x
Phlebosclerosis postmarketing x x x x x x
Tumour necrosis postmarketing, uncommon x x x
Gastric erosions postmarketing x x x x x
Photosensitivity postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x
Chemical cystitis postmarketing x x x x x x x x x x x
Lacrimation postmarketing, common x x x x x x x x x x x x x x x
Embolism arterial postmarketing x x x x x x x
Hyperuricaemia postmarketing x x x x x x x x x x x x x x x x x
Infestation NOS postmarketing x x x x x x x x x x x x x
Necrotising colitis postmarketing x x
Radiation recall reaction (dermatologic) postmarketing x x x x x x x x x x x x x x x x x x x x x x x x
Abscess x x
Lactic acidosis x
Agranulocytosis x x x x
Albuminuria x x x
Aplastic anaemia x
Angina pectoris x
Anuria x
Ascites x x x
Asthma x x x x
Ataxia x
Atrioventricular block x x x x x x
Azoospermia x x x x x x x x x
Balanitis x x
Mental disorder x x x
Blister x x x x x x x x
Bone disorder x x
Bronchitis x x
Bundle branch block x x x x x x x x x x x x x x x x
Candida infection x x x x x x
Skin candida x x
Vaginal moniliasis x x x
Congestive cardiomyopathy x
Cellulitis x x x x x x x x x x x
Neck pain x
Cholangitis sclerosing x x
Colitis x x x x x
Confusional state x x x x x
Cough 0% - 12% x x x x x x
Cryptococcosis x x x x
Cystitis x x
Delirium x x
Dermatitis x x x x x
Drug eruption x
Dermatitis atopic x x
Dermatitis contact x
Fungal skin infection x x x
Diabetes mellitus x x
Diplopia x
Drowsiness x
Dysarthria x
Dyskinesia x
Ecchymosis x x
Eczema x
Effusion x
Eosinophilia x x
Eructation x x
Erythema nodosum x x
Extravasation x x x x x x x x x x x x
Faecalith x x
Folliculitis x x x x x
Furunculosis x x x x
Gastrointestinal haemorrhage x x x
Gingival bleeding x
Glossitis x x x x
Glycosuria x x
Cardiac arrest x x x
Heart malformation x x
Cardiac disorder x x x x x
Cardiomegaly x x x x
Cardiac failure x x x x x x
Haematemesis x
Haematuria x x x x x
Hemiplegia x
Haemoptysis x
Hepatitis x x x x
Hepatomegaly x x
Hepatosplenomegaly x x
Herpes labialis x x x x
Hiccups x x
Hydronephrosis x
Hypercalcaemia x x x x
Hyperaesthesia x
Hyperglycaemia x x x
Hyperkalaemia x x x x
Hyperlipidaemia x x
Hypernatraemia x x
Hyperventilation x x
Hypoaesthesia x x x
Hypocalcaemia x x x x
Hypoglycaemia x x
Hypokalaemia x x x x x x x
Hyponatraemia x x x x x
Hypoproteinaemia x x
Body temperature decreased x x
Immune status x
Inflammation x
Influenza x x
Jaundice x x x
Jaundice cholestatic x x
Arthropathy x
Ketosis x x
Renal failure acute x x
Laryngitis x
Acute lymphocytic leukaemia x x x x x x x x x x x x x
Myeloid leukaemia x
Leukoplakia oral x x
Leukorrhea x
Lung disorder x
Lymphangitis x x
Lymphoedema x x
Lymphopenia x x x
Mastitis x
Melaena x x
Premature menopause x
Multi-organ failure x
Hypotonia x x
Fungal infection x x x x
Myelodysplasia x
Myocarditis x x x
Myositis x x
Necrosis x x x x x x x x x x x x x x
Nervous system disorder x x x x
Nervousness x x
Nocturia x
Nystagmus x
Oligospermia x x x x
Oliguria x x
Optic neuritis x x x x x
Other conjunctivitis x
Otitis media x x
Pancreatitis x x
Pancytopenia x x
Pelvic pain x
Penicillin allergy x x x
Pericardial effusion x x x x x x
Pericarditis x x x
Abscess periodontal x
Petechiae x x x x
Pleural effusion x x x x
Pneumothorax x x
Supraventricular extrasystoles x
Proctitis x
Prostatic disorder x
Psoriasis x x
Pulmonary oedema x x
Purpura x x
Radiation injury x x
Rectal disorder x
Renal failure x x
Scotoma x
Seborrhoeic dermatitis x
Septicemia x x x x x x x x x x x x x x x x
Septic shock x x x x x x x x x x x x
Salivary hypersecretion x
Sinusitis x x x x
Skin nodule x
Gastric ulcer x
Aphthous stomatitis x x x x x
Ulcerative stomatitis x x
Cerebrovascular accident x
Syncope x x x x
Tachycardia x x x x x x x x x
Sinus tachycardia x x x x x
Testicular disorder x
Thrombosis x x x x
Tinnitus x x
Toxoplasmosis x x x x
Tumour lysis syndrome x x x x x
Ureteric obstruction x
Urethral obstruction x
Pollakiuria x
Vasodilation x x
Ventricular tachycardia x x x x x x x x x
Vertigo x x
Viral infection x x
Tachyarrhythmia x x x x x x
Peripheral vascular disorder x
Hepatic failure x x
Agitation x
Mood swings x x x
Rash pustular x x
Onycholysis x x x
Hypochloraemia x
Hyperphosphataemia x
Hypophosphataemia x x
Cystitis haemorrhagic x x
Hypokinesia x x
Hepatic function abnormal x x
Migraine x x
Peripheral sensory neuropathy x x
Blood urea increased x
Creatinine increased x
Diarrhoea haemorrhagic x
Generalised oedema x
Oedema genital x x
Ventricular extrasystoles x x x x
Injection site haemorrhage x x
Hypermagnesaemia x
Hypomagnesaemia x x x x
Injection site inflammation x
Kidney function abnormal x x
Lactic dehydrogenase activity increased x x
Hepatocellular injury x
Liver function test abnormal x
Bone marrow depression x
Skin necrosis x x x x x
Retrosternal pain x x
Eye pain x x
Injection site pain x x
Phosphatase alkaline increased x x x
Prothrombin level increased x x x
Hyporeflexia x
Thromboplastin decreased x
Oesophageal ulcer x x
Polyneuropathy x x
Leukoderma x
Pseudolymphoma x
Injection site infection x x
Oral pain x x x x
Dyspnoea exertional x x
Gallop rhythm x x
Increased appetite x x
Decreased appetite x x
Abdominal pain upper x x
Rectal tenesmus x x
Thinking abnormal x x
Abnormal dreams x
Rash erythematous x x x x
Neurotoxicity x x x
Gravitational oedema x
Urine abnormality x
Bullous eruption x x x x
Leg edema x x x x
Ventricular dysfunction x x
Rectal haemorrhage x x
Hepatobiliary disease x
Eruption x
Dry eye x x
Redness x
Hypolipidaemia x
Red blood cell abnormality x
Warmth x
Dysaesthesia 0% - 10% x x x
Skin scaly x x x x
Rigors x
QRS voltage decreased x x x
Bradycardia x x x x x x x x x x x
Transaminases increased x x
Secondary infection x x
Blindness x x
Lymphadenopathy x x
Electrocardiogram ST segment depression x x x x
Coordination abnormal x
Influenza like illness x x
Paralysis x
Face oedema x x x x
Gait disturbance x x
Stinging x x
Drug interaction x
Bilirubin total increased x
Thrombocytosis x x x
Blood and lymphatic system disorders x x x x x x x
Hand and foot syndrome secondary to sickle cell anaemia x x
Local reaction x x x
Bladder constriction x x x x
Leukemia secondary x x x x x x x x x x x x x x
Alopecia reversible x
Serum bilirubin increased x x
Neutropenic sepsis x x
Myasthenia x x
Left ventricular ejection fraction decreased x x x
Gastrointestinal toxicity x
Ileus x x x
Abnormal pigmentation x x x
Ocular toxicity x
Urine output x x
Sensitisation x x
Parosmia x
Rash papular x x
Dysphonia x
Pneumocystis jirovecii pneumonia x x
Acute cardiac toxicity x
Ageusia x
Proctitis ulcerative x x
Metastatic neoplasm x x
Metastatic disease x x x
Vaginal haemorrhage x
Abnormal vision x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Indication Labels
Acquired immunodeficiency syndrome x x x x x x
Acute leukaemia x x
Acute lymphocytic leukaemia x x x x x x x x x
Acute myeloid leukaemia x x x x x x x x x
Advanced breast cancer x x x
Bladder cancer x x x
Bladder cancer stage IV x
Bladder carcinoma x x x
Bladder neoplasm x x
Bladder transitional cell carcinoma x x
Bladder transitional cell carcinoma metastatic x x
Bone sarcoma x x
Brain neoplasm x x
Breast cancer x x x x x x x x x x x x x x x x x x x x x x x
Breast cancer stage IV x x x x x x x x x
Bronchial carcinoma x x x x x x x
Carcinoma x x x x x x x
Carcinoma breast x x x x x x x x x
Carcinoma of lung x x x
Carcinoma stomach x x x x x x x x x x
Carcinoma testes x x
Cardiac disorder x
Cardiotoxicity x x x x
Drug interaction x
Endometrial cancer x x
Ewing's sarcoma x x x
Generalized illness x x
Hepatic function abnormal x
Hepatocellular carcinoma x x x x
Hodgkin's disease x x x x x x x x x x x
Hypersensitivity x
Immunodeficiency x
Kaposi's sarcoma x
Kaposi's sarcoma AIDS related x x x x x x x
Leukaemia x x
Lymphoma x x x x x x x x x x
Malignant melanoma x x x
Menopause x x
Metastases to liver x x x
Metastasis x x x
Metastatic carcinoma x x
Metastatic gastric adenocarcinoma x x
Neoplasm x x x x x x x x x x x x x x x x x x x x x x
Neoplasm malignant x x x x x x x x x x x x x
Nephroblastoma x x x x x x x x x
Neuroblastoma x x x x x x x x x x
Node-positive breast cancer x x
Non-Hodgkin's lymphoma x x x x x x x x x x x
Non-small cell lung cancer x x x
Osteosarcoma x x
Ovarian cancer x x x x x x x x
Ovarian carcinoma x x x x x x x x
Ovarian epithelial cancer x x x x
Ovarian epithelial cancer stage IV x x
Pancreatic carcinoma x
Plasma cell myeloma x x x x x x x x
Prostate cancer x
Prostate carcinoma x x x
Renal carcinoma x x
Rhabdomyosarcoma x x
Sarcoma x x x x x x x x x x x x x x
Small cell lung cancer x x x x x
Solid tumour x x x x
Squamous cell carcinoma x x
Thymoma x
Thyroid carcinoma x x x x x x x x x x

doxorubicin / doxorubicin hydrochloride

Side effects:44
Source:EMA

Doxorubicin

Side effects:49
Source:BC Cancer

WARNINGS / ADRIAMYCIN Solution for Injection

Side effects:59
Source:medicines.org.au

Epirubicin

Side effects:61
Source:BC Cancer

DOXORUBICIN

Side effects:40
Source:FDA Structured Product Label

DOXORUBICIN

Side effects:55
Source:FDA Structured Product Label

doxorubicin

Side effects:55
Source:FDA Structured Product Label

epirubicin

Side effects:42
Source:FDA Structured Product Label

epirubicin

Side effects:42
Source:FDA Structured Product Label

EPIRUBICIN HYDROCHLORIDE / ELLENCE

Side effects:42
Source:FDA

EPIRUBICIN

Side effects:44
Source:FDA Structured Product Label

epirubicin

Side effects:44
Source:FDA Structured Product Label

epirubicin hydrochloride / Ellence

Side effects:49
Source:FDA

EPIRUBICIN HYDROCHLORIDE / PHARMORUBICIN PFS

Side effects:51
Source:Health Canada

EPIRUBICIN

Side effects:64
Source:FDA Structured Product Label

epirubicin

Side effects:65
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

Powder for Injection / PHARMORUBICIN RD

Side effects:81
Source:medicines.org.au

DOXORUBICIN HYDROCHLORIDE / MYOCET

Side effects:60
Source:Health Canada

DOXORUBICIN

Side effects:93
Source:FDA Structured Product Label

doxorubicin

Side effects:104
Source:FDA Structured Product Label

DOXORUBICIN

Side effects:93
Source:FDA Structured Product Label

doxorubicin / doxorubicin hydrochloride

Side effects:182
Source:EMA

DOXORUBICIN HYDROCHLORIDE / DOXIL

Side effects:232
Source:FDA

DOXORUBICIN HYDROCHLORIDE / CAELYX

Side effects:261
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label