Side effects and indications
Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.)
Information about indications was extracted from the indications and usage sections of the labels.
Show MedDRA Preferred Terms
|
Side effect
|
Data for drug
|
Placebo
|
Labels
(show all 17)
|
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
|
Cough def
|
postmarketing, 7% - 8%
|
2% - 4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cough increased
|
postmarketing, 8%
|
4%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dizziness def
|
postmarketing, 1.9% - 4%
|
1.5% - 3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Angina pectoris def
|
postmarketing, 3%
|
2%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Asthenia def
|
postmarketing, 2%
|
0.699% - 1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Fatigue def
|
2%
|
0.699% - 1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Orthostatic hypotension def
|
postmarketing, 2%
|
1%
|
|
|
|
|
|
|
x
|
|
|
x
|
|
Nausea def
|
postmarketing, 2%
|
1%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Syncope def
|
postmarketing, 2%
|
1%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vertigo def
|
postmarketing, 2%
|
0.7%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vomiting def
|
postmarketing, 2%
|
0.5%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Diarrhoea def
|
postmarketing, 1%
|
0.4%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Kidney function abnormal
|
postmarketing, 1%
|
0.5%
|
|
|
|
|
|
|
x
|
|
|
x
|
|
Abdominal pain def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ageusia def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Alopecia def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Amnesia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anaemia def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Haemolytic anaemia def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anorexia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anxiety def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Arrhythmia def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Arthralgia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Arthritis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bronchospasm def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Bronchitis def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Cerebrovascular disorder def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Chest pain def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Confusional state def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Conjunctivitis def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Constipation def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Convulsion def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Libido decreased def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Dysphagia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dysgeusia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspepsia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspnoea def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oedema def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Enanthema
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Eosinophilia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Toxic epidermal necrolysis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Epistaxis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rash def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Body temperature increased def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Flushing def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Gastroenteritis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Headache def
|
postmarketing
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatitis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypersensitivity def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypoglycaemia def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Hyponatraemia def
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Infection def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Influenza def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Jaundice def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Jaundice cholestatic def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Leukocytosis def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Leukopenia def
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cramp muscle def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Nasal congestion def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Necrosis def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Nervousness def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Neuralgia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Neutropenia def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Pain def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Palpitations def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pancreatitis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pancytopenia def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Paraesthesia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pemphigoid def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pemphigus def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Polyneuritis def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Proteinuria def
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pruritus def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Psoriasis def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Purpura def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Raynaud's disease def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Renal artery stenosis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Respiratory tract infection def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Salivation def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Salivary hypersecretion def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
|
Sinusitis def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sleep disturbance
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Arterial stenosis def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Sweating def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tachycardia def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Thrombocytopenia def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tinnitus def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tremor def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Erythema def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Upper respiratory tract infection def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urticaria def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vasculitis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Visual impairment def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Weight increased def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dry mouth def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatic failure def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Agitation def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Oedema peripheral def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Onycholysis def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Lower respiratory tract infection
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Antinuclear antibody positive def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Creatinine increased def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Necrolysis epidermal
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatocellular injury
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Bone marrow depression def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hepatic necrosis def
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Acute hepatic failure def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Lightheadedness
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
Malaise def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myalgia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Abdominal discomfort
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Discomfort def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Psoriasis flare-up
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Erectile dysfunction def
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anaphylactoid reaction
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Depressed mood def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Photosensitivity def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rash maculo-papular def
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Neuropathy def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vascular stenosis
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Sweating increased
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypertensive
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Insomnia def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Ischaemic stroke
|
postmarketing
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Urine output increased
|
postmarketing
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hearing impaired def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Insufficiency renal def
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Somnolence def
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Erythema multiforme def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Nephropathy def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Renal failure acute def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Pneumonia def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Pulmonary eosinophilia def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Renal failure def
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Hepatic function abnormal
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
Red blood cell sedimentation rate increased
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
Liver function test abnormal
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
Endometrial stromal sarcoma def
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Indication
|
Labels
|
|
Acute myocardial infarction
|
x
|
|
|
|
|
|
x
|
|
|
x
|
|
Agranulocytosis def
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
|
|
|
Angioedema def
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
|
|
|
Angiopathy def
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
|
|
|
Arterial disorder def
|
x
|
x
|
|
|
|
|
|
x
|
|
x
|
|
Cardiac failure def
|
x
|
|
|
|
|
|
x
|
|
|
x
|
|
Cardiac failure congestive def
|
x
|
|
|
|
|
|
x
|
|
|
|
|
Cerebrovascular accident def
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Coronary artery disease def
|
x
|
|
|
|
|
|
|
x
|
|
x
|
|
Death
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Diabetes mellitus def
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Disease progression def
|
x
|
|
|
|
|
|
x
|
|
|
|
|
Essential hypertension def
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
High density lipoprotein decreased
|
x
|
x
|
|
|
|
|
x
|
|
|
|
|
Hypertension def
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hypotension def
|
|
|
|
|
|
|
|
|
|
x
|
|
Infarction def
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Left ventricular dysfunction def
|
|
|
|
|
|
|
|
|
|
x
|
|
Microalbuminuria
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Myocardial infarction def
|
x
|
x
|
|
|
|
|
x
|
x
|
|
x
|
|
Peripheral arterial disease def
|
|
|
|
|
|
|
|
x
|
|
x
|
|
Peripheral vascular disorder def
|
x
|
x
|
|
|
|
|
x
|
|
|
|
|
Renal impairment def
|
x
|
x
|
x
|
x
|
|
x
|
x
|
|
|
|
|
Renal vessel disorder
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Renovascular hypertension def
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Ventricular dysfunction def
|
|
|
|
|
|
|
|
|
|
x
|
|
Information
More information: STITCH, PubChem and possibly Wikipedia or Medpedia
ATC Code:
C09AA05
Legend
Color scheme:
standard – alternative
|
100%
|
|
|
|
75%
|
|
|
|
50%
|
|
|
|
10%
|
|
|
|
frequent (1% to 100%)
|
|
|
|
infrequent (0.1% to 1%)
|
|
|
|
rare (<0.1%)
|
|
|
|
postmarketing
|
|
|
|
0%
|
|
|
|
no frequency information
|
|
|
|
not found on label
|
|
|
Labels
Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.
- RAMIPRIL / ALTACE :
6 side effects
(Drugs@FDA)
- RAMIPRIL :
76 side effects
(FDA XML label)
- RAMIPRIL :
85 side effects
(FDA XML label)
- RAMIPRIL :
89 side effects
(FDA XML label)
- RAMIPRIL :
89 side effects
(FDA XML label)
- Ramipril :
91 side effects
(FDA XML label)
- RAMIPRIL :
94 side effects
(FDA XML label)
- RAMIPRIL / APO-RAMIPRIL :
95 side effects
(Health Canada)
- RAMIPRIL / CO RAMIPRIL :
116 side effects
(Health Canada)
- RAMIPRIL / ALTACE :
121 side effects
(Health Canada)
|