Cyclosporine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 11)
1 2 3 4 5 6 7 8 9 10
Tremor def 3% - 55% x x x x x x x x
Hypertension def postmarketing — 0% - 53% x x x x x x x x
Hirsutism def postmarketing, 21% - 45% x x x x x x
Headache def postmarketing, 2% - 25% x x x x x x x x
Infection def postmarketing, 0% - 24.7% x x x x x x x x
Nausea def postmarketing — 2% - 24% x x x x x x x x
Urinary tract infection def 0% - 21.1% x x x x x
Creatinine increased def postmarketing, 15.7% - 19.8% x x x
Hypertrichosis def postmarketing — 0% - 19% x x x x x
Viral infection def postmarketing, 15.9% - 18.4% x x x x x x
Diarrhoea def postmarketing — 3% - 18% x x x x x x x x
Gingival hyperplasia def postmarketing — 1% - 16% x x x x x x x x
Hyperplasia def postmarketing — 1% - 16% x x x x x x x x
Stomatitis def 5% - 16% x x
Abdominal pain def postmarketing — 2.7% - 15% x x x x
Pain def postmarketing — 1% - 15% x x x x x x x x x
Oedema def rare, 1% - 14% x x x x x x x x
Vomiting def postmarketing — 2% - 14% x x x x x x x x
Dyspepsia def postmarketing, 2.2% - 12% x x x x
Rash def postmarketing — 7% - 12% x x x x x
Fatigue def rare, 3% - 12% x x x x
Cramps of lower extremities 1% - 12% x x
Cramp muscle def rare, 0% - 12% x x x x x x x
Muscle contractions involuntary 1% - 12% x
Respiratory tract infection def 7.7% - 11.3% x x x x
Upper respiratory tract infection def 7.7% - 11.3% x x x x
Dysuria def 0% - 11% x x
Paraesthesia def postmarketing, 1% - 11% x x x x x x x x
Rhinitis def 0% - 11% x x
Skin infection def 7% - 10.1% x x x x x
Influenza def postmarketing, 0% - 9.9% x x x x x
Fungal infection def postmarketing, 2.2% - 9.6% x x x x x x
Pneumonia def 0% - 9.2% x x x x x
Dizziness def postmarketing, 3% - 8% x x x x x
Sinusitis def 1% - 8% x x x x x
Cough def 3% - 7% x x
Abdominal discomfort postmarketing, 0% - 7% x x x x x x
Discomfort def postmarketing, 0% - 7% x x x x x x
Arrhythmia def 1% - 6% x x
Arthralgia def postmarketing, 1.1% - 6% x x x x x x
Chest pain def postmarketing, 1% - 6% x x x x x x
Leukopenia def postmarketing, 0% - 6% x x x x x x
Lymphoma def 0.3% - 6% x x x x x x x
Pharyngitis def 3% - 6% x x x x
Hypomagnesaemia def postmarketing — 0% - 6% x x x x x x x x
Acne def postmarketing, 1% - 6% x x x x x x
Nephropathy toxic 5.4% - 5.7% x x x x x x
Abscess def postmarketing, 4.4% - 5.3% x x x x x x
Septicemia def 4.8% - 5.3% x x x x x
Bronchospasm def postmarketing, 4.9% - 5% x x x
Convulsion def 1% - 5% x x x x x x x x
Dyspnoea def 1% - 5% x x
Ear disorder def 0% - 5% x x
Flatulence def 1% - 5% x x
Flushing def postmarketing, 0% - 5% x x x x x x x x
Arthropathy def 0% - 5% x x
Alopecia def 0% - 4% x x x x
Body temperature increased def postmarketing, 0% - 4% x x x x x x x x
Gastrointestinal disorder def 0% - 4% x x x x
Gingivitis def 0% - 4% x x
Gynaecomastia def rare, 1% - 4% x x x x x x x
Leukorrhea def 0% - 4% x x
Purpura def 0% - 4% x x
Skin ulcer def 0% - 4% x x
Ulcer def postmarketing, 0% - 4% x x x x x x
Pollakiuria def postmarketing, 1% - 4% x x x
Bullous eruption 0% - 4% x x
Eruption 0% - 4% x x
Rigors 0% - 4% x x
Insomnia def postmarketing, 0% - 4% x x x x x
Systemic mycosis 2.2% - 3.9% x x x x x
Anorexia def rare, 0% - 3% x x x x x x x x
Bronchitis def 0% - 3% x x
Haemorrhage def postmarketing, 0% - 3% x x x x x x
Menstrual disorder def 0% - 3% x x
Migraine def 0% - 3% x x
Rectal haemorrhage def 0% - 3% x x
Nephrosis lower nephron def 1% - 2.6% x x x x x x
Necrosis def 1% - 2.6% x x x x x x
Renal tubular disorder def 1% - 2.6% x x x x x x
Renal tubular necrosis 1% - 2.6% x x x x x x
Lymphoproliferative disorder def 0.3% - 0.4% x x x x x x x x
Abdominal distension def postmarketing x x x
Anaemia def postmarketing, rare x x x x x x x x
Haemolytic anaemia def rare x x x x x x x x
Angioedema def postmarketing x x x
Anxiety def postmarketing x x x x x x
Asthenia def postmarketing x x x
Bacterial infection def postmarketing x x x
Coagulopathy def postmarketing x x x
Bursitis def postmarketing x x x
Neoplasm malignant def postmarketing x x x x x
Candidiasis def postmarketing x x x
Carcinoma def postmarketing x x x x x
Cellulitis def postmarketing x x x
Confusional state def postmarketing x x x x x x x x
Conjunctivitis def postmarketing x x x x x x
Constipation def postmarketing x x x x x x
Cyst def postmarketing x x x
Deafness def postmarketing x x x
Libido decreased def postmarketing x x x
Dysphagia def postmarketing x x x x x x
Dermatitis def postmarketing x x x
Diabetes mellitus def postmarketing x x x
Distention def postmarketing x x x
Dysgeusia def postmarketing x x x
Eczema def postmarketing x x x
Enanthema postmarketing x x x
Epistaxis def postmarketing x x x
Eructation def postmarketing x x x
Oesophagitis def postmarketing x x x
Folliculitis def postmarketing x x x
Gastritis def postmarketing x x x x x x
Gastroenteritis def postmarketing x x x
Gingival bleeding def postmarketing x x x
Glossitis def postmarketing x x x
Goitre def postmarketing x x x
Gout def postmarketing x x x
Cardiac failure def postmarketing x x x
Haematuria def postmarketing x x x x x x
Haemolytic uraemic syndrome def rare x x
Herpes NOS def postmarketing x x x
Herpes simplex def postmarketing x x x
Herpes zoster def postmarketing x x x
Hyperbilirubinaemia def postmarketing x x x
Hyperaesthesia def postmarketing x x x
Hyperglycaemia def rare x x x x x x x x
Hyperkalaemia def postmarketing, rare x x x x x
Hyperlipidaemia def rare x x x x
Hypersensitivity def postmarketing x x x x x x
Hypertriglyceridaemia def postmarketing x x x
Hypertrophy def postmarketing x x x
Salivary gland enlargement postmarketing x x x
Hypoaesthesia def postmarketing x x x
Hypoglycaemia def postmarketing x x x
Incontinence def postmarketing x x x
Libido increased def postmarketing x x x
Infarction def postmarketing x x x x x x
Ischaemia def postmarketing x x x
Keratosis def postmarketing x x x
Lethargy def postmarketing x x x x x x
Breast pain def postmarketing x x x
Myopathy def rare x x
Myocardial infarction def postmarketing x x x x x x
Myositis def postmarketing x x
Nail disorder def postmarketing x x x
Neoplasm def postmarketing x x x x x
Nervousness def postmarketing x x x
Nightmare def postmarketing x x x
Nocturia def postmarketing x x x
Pancreatitis def rare x x x x x x x x
Papilloedema def rare x x
Peptic ulcer def postmarketing x x x x x x
Pigmentation def postmarketing x x x
Polyuria def postmarketing x x x
Pruritus def postmarketing x x x x x x x
Benign intracranial hypertension def rare x x
Pyelonephritis def postmarketing x x x
Renal failure def postmarketing x x x x x
Rhabdomyolysis def postmarketing x x
Skin disorder def postmarketing x x x
Gastric ulcer def postmarketing x x x
Sweating def postmarketing x x x x x x
Thrombocytopenia def rare x x x x x x x x
Tinnitus def postmarketing x x x x x x
Tongue disorder postmarketing x x x
Tonsillitis def postmarketing x x x
Tooth disorder def postmarketing x x x
Urinary incontinence def postmarketing x x x
Urticaria def postmarketing x x x
Uterine haemorrhage def postmarketing x x x
Vertigo def postmarketing x x x
Vestibular disorder def postmarketing x x x
Visual impairment def postmarketing, rare x x x x x
Weight increased def postmarketing, rare x x x x x
Weight decreased def postmarketing x x x x x x
Dry mouth def postmarketing x x x
Encephalopathy def rare x x
Micturition urgency def postmarketing x x x
Mood swings postmarketing x x x
Synovial cyst def postmarketing x x x
Cataract def postmarketing x x x
Hepatic function abnormal rare x x
Renal abscess postmarketing x x x
Blood urea increased postmarketing x x x
Intracranial pressure increased def rare x x
Hepatocellular injury postmarketing x x x
Muscular weakness def rare x x
Eye pain def postmarketing x x x x
Dry skin def postmarketing x x x
Tendon disorder postmarketing x x x
Polyneuropathy def rare x x
Abnormal chest sounds NOS postmarketing x x x
Malaise def postmarketing x x x
Myalgia def postmarketing, rare x x x x x x x x
Increased appetite postmarketing x x x
Consciousness abnormal rare x x
Cerebration impaired def postmarketing x x x
Peripheral ischaemia def postmarketing x x x
Urine abnormality postmarketing x x x
Uraemic syndrome rare x x x x x x x x
Stiffness postmarketing x x x
Neuropathy def postmarketing x x x
Lymphadenopathy def postmarketing x x x
Heart sounds abnormal postmarketing x x x
Hot flush def postmarketing x x x
Sweating increased postmarketing x x x
Hyperuricaemia def postmarketing, rare x x x x x
Progressive renal failure postmarketing x x x
Graft loss postmarketing x x x
Abnormal pigmentation def postmarketing x x x
Fibroadenosis of breast postmarketing x x x
Death postmarketing x x x
Weakness def postmarketing, rare x x x x x x x x
Gout attack postmarketing x x x
Somnolence def postmarketing x x x
Ataxia def x x
Mental disorder def x x x x
Skin cancer def x x
Cardiovascular disorder def x x
Cerebellar ataxia def x x
Coma def x x
Gastrointestinal haemorrhage def x x x x x x
Gingival disorder def x
Hiccups def x x x x x x
Hodgkin's disease def x x
Hyperaemia def x
Hypotrichosis def x x
Musculoskeletal disorder def x x
Nervous system disorder def x x x x x x
Night sweats def x x x x x x
Obstruction def x x x x x x
Paresis def x x
Neuropathy peripheral def x x
Respiratory disorder def x x
Thrombosis def x x x x x x
Upper gastrointestinal haemorrhage def x x x x x x
Urinary tract disorder def x x
Agitation def x x
Hypocholesterolaemia def x x x x x x
Lacrimation increased def x
Blindness cortical def x x
Microangiopathy x x x x x x
Microangiopathic haemolytic anaemia x x x x x x
Stomach ache def x x
Function kidney decreased x x x x x x
Disorientation x x
Sensation of heat x x
Anaphylactoid reaction x
Vision blurred def x
Sensation of foreign body def x
Gastrointestinal symptom NOS x x
Blindness def x x
Visual disturbance x x x x x x x x x
Stinging x
Unspecified disorder of autonomic nervous system def x x
Transplant failure x x x x x x
Hearing impaired def x x x x x x
Conjunctival hyperaemia x
Tingling sensation def x x x x x x
Indication Labels
Anaphylactic shock def x x
Arthritis def x x x x x x
Cancer in remission x x x
Dental plaque def x x x
Glomerulonephritis def x x x
Glomerulonephritis membranous def x x x
Glomerulosclerosis def x x x
Graft versus host disease def x x x
Inflammation def x
Keratoconjunctivitis def x
Keratoconjunctivitis sicca def x
Lacrimation def x
Lipoid nephrosis def x x x
Nephropathy def x x x
Nephrotic syndrome def x x x
Plaque psoriasis x x x
Psoriasis def x x x x x x
Rheumatoid arthritis def x x x x x x
Sicca syndrome def x
Therapy cessation x x x
Transplant rejection def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: L04AD01, S01XA18

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. CYCLOSPORINE / NEORAL 25MG : 1 side effect (Health Canada)
  2. CYCLOSPORINE / RESTASIS : 10 side effects (Drugs@FDA)
  3. CYCLOSPORINE / APO-CYCLOSPORINE ORAL SOLUTION : 80 side effects (Health Canada)
  4. CYCLOSPORINE / SANDOZ CYCLOSPORINE : 81 side effects (Health Canada)
  5. CYCLOSPORINE : 84 side effects (FDA XML label)
  6. CYCLOSPORINE / SANDIMMUNE : 84 side effects (Drugs@FDA)
  7. Cyclosporine : 85 side effects (FDA XML label)
  8. CYCLOSPORINE : 178 side effects (FDA XML label)
  9. CYCLOSPORINE / NEORAL : 223 side effects (Drugs@FDA)
  10. CYCLOSPORINE : 225 side effects (FDA XML label)