Naproxen

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 28)
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Agranulocytosis def postmarketing x x x x x x x x x
Alopecia def postmarketing x x x x x x x x x
Anaphylactic shock def postmarketing x x x x x x x
Anaemia def postmarketing x x x x x x x x x
Aplastic anaemia def postmarketing x x x x x x x x x
Haemolytic anaemia def postmarketing x x x x x x x x x
Angioedema def postmarketing x x x x x x x x x
Anxiety def postmarketing x x x x x x x x
Arrhythmia def postmarketing x x x x x x x x
Asthenia def postmarketing x x x x x x x x
Asthma def postmarketing x x x x x x x x x
Blister def postmarketing x x x x x x x
Breast feeding def postmarketing x
Colitis def postmarketing x x x x x x x x x
Coma def postmarketing x x x x x x x
Confusional state def postmarketing x x x x x x x x
Conjunctivitis def postmarketing x x x x x x x x
Convulsion def postmarketing x x x x x x x x
Corneal opacity def postmarketing x x x x x x x
Cystitis def postmarketing x x x x x x x x
Dermatitis def postmarketing x x x x x x x x x
Dermatitis exfoliative def postmarketing x x x x x x x x
Drug eruption def postmarketing x x x x x x
Dizziness def postmarketing x x x x x x x
Patent ductus arteriosus def postmarketing x
Riley-Day syndrome def postmarketing x
Abnormal labour def postmarketing x
Dysuria def postmarketing x x x x x x x x
Oedema def postmarketing x x x x x x x x x
Enterocolitis def postmarketing x
Eosinophilia def postmarketing x x x x x x x x x
Toxic epidermal necrolysis def postmarketing x x x x x x x
Epidermolysis bullosa def postmarketing x x x x x x x x
Eructation def postmarketing x x x x x x x
Erythema multiforme def postmarketing x x x x x x
Erythema nodosum def postmarketing x x x x x x
Oesophagitis def postmarketing x x x x x x x x x
Rash def postmarketing x x x x x x x x x x
Gastritis def postmarketing x x x x x x x x
Gastrointestinal haemorrhage def postmarketing x x x x x x x x
Glossitis def postmarketing x x x x x x x
Hallucination def postmarketing x x x x x x x
Cardiac failure def postmarketing x x x x x x x x
Cardiac failure congestive def postmarketing x x x x x x x x
Heartburn def postmarketing x x x x x x x
Haematemesis def postmarketing x x x x x x x x
Haematuria def postmarketing x x x x x x x x x
Haemorrhage def postmarketing x x x x x x x x x x
Hepatitis def postmarketing x x x x x x x x
Hyperglycaemia def postmarketing x x x x x x x x x
Hyperkalaemia def postmarketing x x x x x x x x x
Hypertension def postmarketing x x x x x x x x x
Pulmonary hypertension def postmarketing x
Hypoglycaemia def postmarketing x x x x x x x x x
Hypotension def postmarketing x x x x x x x
Infarction def postmarketing x x x x x x x x
Infection def postmarketing x x x x x x x x
Infertility def postmarketing x x x x x x
Jaundice def postmarketing x x x x x x x x x
Nephropathy def postmarketing x x x x x x x x x
Renal papillary necrosis def postmarketing x x x x x x x x x
Premature labour def postmarketing x
Leukopenia def postmarketing x x x x x x x x x
Lichen unspecified def postmarketing x x x x x x
Lichen planus def postmarketing x x x x x x
Melaena def postmarketing x x x x x x x x
Meningitis def postmarketing x x x x x x x x
Meningitis aseptic def postmarketing x x x x x x x x
Menstrual disorder def postmarketing x x x x x x x x
Myocardial infarction def postmarketing x x x x x x x x
Necrosis def postmarketing x x x x x x x x x
Nephritis def postmarketing x x x x x x x x x
Nephritis interstitial def postmarketing x x x x x x x x
Nephrotic syndrome def postmarketing x x x x x x x x x
Nervousness def postmarketing x x x x x x x x
Neuritis def postmarketing x x x x x x x x
Oliguria def postmarketing x x x x x x x
Pancreatitis def postmarketing x x x x x x x x x
Pancytopenia def postmarketing x x x x x x
Papilloedema def postmarketing x x x x x x
Paraesthesia def postmarketing x x x x x x x x
Peptic ulcer def postmarketing x x x x x x x x x
Pneumonia def postmarketing x x x x x x x x x
Polyuria def postmarketing x x x x x x x
Porphyria def postmarketing x x x x x x x x
Proteinuria def postmarketing x x x x x x x
Pulmonary oedema def postmarketing x x x x x x x
Pulmonary eosinophilia def postmarketing x x x x x x x x
Renal failure def postmarketing x x x x x x x x x
Stomatitis def postmarketing x x x x x x x x x
Ulcerative stomatitis postmarketing x x x x x x x x
Swelling def postmarketing x
Syncope def postmarketing x x x x x x x x
Tachycardia def postmarketing x x x x x x x x
Thrombocytopenia def postmarketing x x x x x x x x x
Tremor def postmarketing x x x x x x x
Ulcer def postmarketing x x x x x x x x x
Erythema def postmarketing x x x x x x x x x
Urticaria def postmarketing x x x x x x x x x
Uterine haemorrhage def postmarketing x
Vasculitis def postmarketing x x x x x x x x x
Vomiting def postmarketing x x x x x x x x
Dry mouth def postmarketing x x x x x x x
Chills def postmarketing x x x x x x x x x
Fever chills postmarketing x x x x x x x x
Hepatic failure def postmarketing x x x x x x x
Hepatic function abnormal postmarketing x x x x x x x x
Necrolysis epidermal postmarketing x x x x x x x x x
Haemorrhage intracranial def postmarketing x
Liver function test abnormal postmarketing x x x x x x x
Muscular weakness def postmarketing x x x x x x x x x
Porphyria cutanea tarda def postmarketing x x x x x x x
Photosensitivity reaction def postmarketing x x x x x x x x x
Fixed drug eruption postmarketing x x x x x x
Malaise def postmarketing x x x x x x x x x
Teratogenicity def postmarketing x
Respiratory depression postmarketing x x x x x x x
Cerebration impaired def postmarketing x x x x x x x x x
Sepsis def postmarketing x x x x x x x
Rectal haemorrhage def postmarketing x x x x x x x x
Fluid retention postmarketing x
Eruption postmarketing x x x x x x x x x
Redness def postmarketing x
Epidermolysis postmarketing x x x x x x x x
Cognitive impairment def postmarketing x x x x x x x x
Anaphylactoid reaction postmarketing x x x x x x x x
Vision blurred def postmarketing x x x x x x x
Photosensitivity def postmarketing x x x x x x x x x
Lupus erythematosus def postmarketing x x x x x x
Lymphadenopathy def postmarketing x x x x x x x
Necrotizing enterocolitis def postmarketing x
Pseudoporphyria postmarketing x x x x x x x x
Skin fragility postmarketing x x x x x x x
Drug interaction def postmarketing x
Insomnia def postmarketing x x x x x x x x x
Gastrointestinal oedema postmarketing x
Death postmarketing x x x x x x x
Hearing impaired def postmarketing x x x x x x x
Weakness def postmarketing x x x x x x x x x
Somnolence def postmarketing x x x x x x
Abdominal pain def x x x x x x x
Abscess def x
Albuminuria def x
Alkalosis def x
Amblyopia def x
Amnesia def x
Angina pectoris def x
Anorexia def x
Aortic valve stenosis def x
Arthralgia def x
Mental disorder def
Bone disorder def x
Breast disorder def
Bronchitis def x
Bundle branch block def x
Carcinoma def x
Cellulitis def x
Neck pain def x
Chest pain def x
Cholecystitis def x
Cholelithiasis def x
Cholestasis def x
Colitis ulcerative def x
Constipation def x x x x x x x
Cough def x
Dysphagia def x
Dehydration def x
Dermatitis contact def x
Type 2 diabetes mellitus def x
Diarrhoea def x x x x x x x x x x
Diplopia def x
Drowsiness def x x x x x x x
Dyspepsia def x x x x x x x x x
Dyspnoea def x x x x x x x
Ear disorder def x
Ecchymosis def x x x x x x x
Eczema def x
Epistaxis def x
Oesophageal achalasia def x
Oesophageal disorder def x
Eye disorder def
Fatigue def x
Flatulence def x x x x x x x x
Pathological fracture def x
Gastroenteritis def x
Glycosuria def x
Cardiac disorder def
Haematoma def x
Subdural haematoma def x
Hepatosplenomegaly x
Herpes NOS def x
Herpes simplex def x
Herpes zoster def x
Hypercholesterolaemia def x
Hypersensitivity def x
Hypokalaemia def x
Immune system disorder def
Incontinence def x
Infertility female def
Inflammatory bowel disease def x
Influenza def
Unspecified disorder of intestine def x
Arthropathy def x
Keratoconjunctivitis def x
Calculus of kidney def x
Lacrimal disorder def x
Laryngitis def x
Lung disorder def x
Systemic lupus erythematosus def x x x
Mediastinal disorder def
Menorrhagia def x
Metrorrhagia def x
Hypertonia def x
Muscle rigidity def x
Nail disorder def x
Nail-patella syndrome def x
Nausea def x x x x x x x
Neoplasm def x
Nephrosclerosis def x
Nervous system disorder def
Neuralgia def x
Nodule def x
Nocturia def x
Optic neuritis def x x x x x x
Otitis def x
Otitis media def x
Palpitations def x x x x x x x x x
Pelvic pain def x
Abscess periodontal def x
Pharyngitis def x
Ptosis def x
Prostatic disorder def x
Pruritus def x x x x x x x x x
Purpura def x x x x x x x x x
Pyelonephritis def x
Pyuria def x
Rectal disorder def x
Respiratory disorder def x
Rhinitis def x
Scleritis def x
Sinusitis def x
Neoplasm skin def x
Skin ulcer def x
Muscle spasms def x
Gastric disorder def x x
Gastric ulcer def x
Aphthous stomatitis def x
Cerebrovascular accident def x
Sweating def x x x x x x x x x
Thirst def x x x x x x x x
Thrombophlebitis def x
Tinnitus def x x x x x x x
Tooth disorder def x
Pollakiuria def x
Urinary incontinence def x
Urinary tract infection def x
Urinary tract disorder def
Vaginal inflammation def x
Angiopathy def
Vasodilation def x
Vertigo def x x x x x x x x x x
Weight decreased def x
Urinary retention def x
Neuritis retrobulbar x x x x x x
Mood swings x
Oedema peripheral def x x
Cataract def x
Mouth ulceration def x
Migraine def x
Neck stiffness x
Bleeding time prolonged x x x x x x x x
Blood urea increased
Kidney function abnormal x x x x x x
Renal tubular disorder def x x
Mucous membrane disorder x
Skin necrosis x
Subcutaneous nodule x
Bone pain def x
Eye pain def x
Dry skin def x
Tendon disorder x
Deep thrombophlebitis x
Oesophageal ulcer def x
Uterine spasm x
WBC abnormal NOS
Vascular anomaly def x
Lightheadedness x x x x x x x x x
Urine abnormality x
Hepatic enzyme increased x x x x x x x
Hepatobiliary disease def
Renal impairment def x
Red blood cell abnormality x
Enlargement abdomen def x
Lacrimation def x
Respiratory distress def x
Electrocardiogram abnormal x
Paralysis def x
Reaction gastrointestinal x x x x x x x x x
Visual disturbance x x x x x x x x x
Renal pain x
Cough increased x
Carcinoma breast def x
Serum creatinine increased x x x x x x
Acne def x
Dissecting aortic aneurysm, thoracic
Hyperuricaemia def x
Arterial disorder def x
Hypertensive x
Myasthenia def x
Hepatic impairment x
Breast neoplasm def x
Renal tubular necrosis x
Coronary artery disease def x
Indication Labels
Acute pain def x x x
Adverse event def x
Ankylosing spondylitis def x x x x x x x x
Arthritis def x x x x x x x x x
Bursitis def x x x x x x
Dysmenorrhoea def x x x x x x
Gout def x x x x x
Gout acute x x x x x
Gouty arthritis def x
Juvenile arthritis def x x x x x x x
Osteoarthritis def x x x x x x x x x
Pain def x x x x x x x x
Premenstrual syndrome def x
Primary dysmenorrhea x x x x x x
Rheumatoid arthritis def x x x x x x x x x
Spondylitis def x x x x x x x x
Subacromial bursitis x
Supraspinatus tendonitis x
Tendonitis def x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Codes: G02CC02, M01AE02, M02AA12

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. naproxen : 8 side effects (FDA XML label)
  2. NAPROXEN / PMS-NAPROXEN EC : 104 side effects (Health Canada)
  3. Naproxen : 135 side effects (FDA XML label)
  4. NAPROXEN : 137 side effects (FDA XML label)
  5. NAPROXEN : 138 side effects (FDA XML label)
  6. NAPROXEN : 142 side effects (FDA XML label)
  7. Naproxen : 143 side effects (FDA XML label)
  8. NAPROXEN : 149 side effects (FDA XML label)
  9. naproxen delayed-release tablets / EC-Naprosyn : 162 side effects (FDA MedWatch)
  10. NAPROXEN (NAPROXEN SODIUM) / NAPRELAN : 223 side effects (Health Canada)