Dofetilide

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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Side effect Data for drug Placebo Labels
1 2
Tachycardia def 2.6% - 15.8% 2.5% - 13.6% x x
Torsade de pointes def 0.3% - 15.8% 2.7% - 13.6% x x
Ventricular tachycardia def 2.6% - 15.8% 2.5% - 13.6% x x
Headache def 11% 9% x x
Chest pain def 10% 7% x x
Pain def 3% - 10% 2% - 7% x x
Dizziness def 8% 6% x x
Infection def 7% 5% x x
Respiratory tract infection def 7% 5% x x
Dyspnoea def 6% 5% x x
Nausea def 5% 4% x x
Ventricular fibrillation def 0.3% - 4.8% 0.1% - 3.1% x x
Influenza def 4% 2% x x
Insomnia def 4% 3% x x
Abdominal pain def 3% 2% x x
Back pain def 3% 2% x x
Diarrhoea def 3% 2% x x
Rash def 3% 2% x x
Atrioventricular block def 0.4% - 1.5% 0.3% - 2.7% x x
Block heart def 0.1% - 1.2% 0.1% - 0.8% x x
Bundle branch block def 0.1% - 0.5% 0.1% - 0.4% x x
Angina pectoris def x x
Angioedema def x x
Anxiety def x x
Arthralgia def x x
Asthenia def x x
Cough def x x
Sudden death def x x
Oedema def x x
Facial paralysis def x x
Cardiac arrest def x x
Cardiac disorder def x x
Cardiac failure def x x
Hypertension def x x
Infarction def x x
Ischaemia def x x
Myocardial infarction def x x
Palpitations def x x
Paraesthesia def x x
Cerebrovascular accident def x x
Sweating def x x
Syncope def x x
Supraventricular tachycardia def x x
Urinary tract infection def x x
Paralysis flaccid x x
Oedema peripheral def x x
Migraine def x x
Hepatocellular injury x x
Arrhythmia supraventricular def x x
Bradycardia def x x
Paralysis def x x
Cough increased x x
Cerebral ischaemia def x x
Death x x
Indication Labels
Arrhythmia def x x
Atrial fibrillation def x x
Atrial flutter def x x
Cardiac fibrillation x x
Cardiac flutter x x
Paroxysmal atrial fibrillation def x x
Sinus rhythm x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: C01BD04

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. dofetilide : 54 side effects (FDA XML label)
  2. dofetilide / Tikosyn : 54 side effects (FDA MedWatch)