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Thalidomide

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L04AX02

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Infestation NOS 59.4% 59.5% x x x
Gastrointestinal disorder 11.1% - 69.2% 9.48% - 64.2% x x x x x x x x x
Somnolence 11.4% - 37.5% 11.4% x x x x x x x x x x
Angiopathy 17.9% - 39.3% 6.03% - 22.8% x x x
Malnutrition 14.1% - 41% 14.7% - 38.4% x x
Mental disorder 8.12% - 38.5% 3.45% - 41.8% x x x
Endocrine disorder 4.17% - 37.5% 22.9% x x x x x x x x
Rash 0% - 31.4% 31.4% x x x x x x x x x x
Nervous system disorder very common, 20.1% - 68.8% 8.62% - 59.5% x x x x x x x x x
Body temperature increased 0% - 23.5% 17.1% x x x x x x x x x
Leukopenia 0% - 25.8% 0.431% - 8.57% x x x x x x x x x x
Hyperglycaemia 1.96% - 79.4% 13.8% x x x x x x x
Cardiac disorder 15% 11.6% x x x
Fatigue 1.96% - 79.4% 15.5% x x x x x
Headache 0% - 22.5% 11.4% x x x x x x x x x x
Deep vein thrombosis 11.5% - 12.8% 1.72% x x x
Dyspnoea postmarketing, 2.94% - 42.2% x x x x x x x x x
Mediastinal disorder 11.5% 5.6% x x x
Pneumonia 7.26% - 15% 6.03% - 12.1% x x x x x x x x x
Peripheral sensory neuropathy 10.3% 5.17% x x x x
Blood and lymphatic system disorders 10.3% 7.33% x x x
Thrombocytopenia 0% - 11.3% 0% x x x x x x x x x x
Muscular weakness 0.98% - 40.2% x x
Depressed level of consciousness 2.94% - 15.7% x
Asthenia 2.9% - 23.9% 1.72% - 20.3% x x x x x x x x x x
Lymphopenia postmarketing, 0% - 12.1% 0% x x x x x x x x x
Anaemia 0% - 14.5% 0.431% - 8.57% x x x x x x x x x x
Embolism 1.96% - 22.5% x x
Thrombosis 1.96% - 22.5% x x x x x x x
Bone pain 0% - 36.3% x
Pulmonary embolism 6.84% 1.72% x x x x x x x x x
Pruritus 2.78% - 8.33% 5.71% x x x x x x x x
Confusional state 1.96% - 28.4% 0.862% x x x x x x x x x
Oedema 0% - 56.9% 8.19% x x x x x x x x x
Hypocalcaemia postmarketing, 0.98% - 71.6% x x x x x x x
Dry mouth 0% - 11.8% 5.71% x x x x x x x x x
Pain 0% - 64.7% 5.71% x x x x x x x x
Pharyngitis 4.17% - 8.33% 5.71% x x x x x x x
Rash maculo-papular 4.17% - 18.8% 5.71% x x x x x x x
Paraesthesia 0% - 15.6% 6.47% - 11.4% x x x x x x x x x x
Lymphadenopathy 0% - 12.5% 8.57% x x x x x x x
Hypotension 1.96% - 15.7% x x x x x x x x x
Hypertension 0% - 11.8% x x x x x x x x
Infection postmarketing, 0% - 59.4% 2.86% - 59.5% x x x x x x x x x
Febrile neutropenia postmarketing, 1.96% - 27.5% x x x x x x x
Hyperlipidaemia 0% - 9.4% 2.86% x x x x x x x x
Back pain 0% - 5.6% 0% x x x x x x x
Oral candidiasis 0% - 11.1% 0% x x x x x x x
Constipation 0% - 54.9% 0% - 21.1% x x x x x x x x x x
Fungal skin infection 0% - 9.4% 0% x x x x x x x
Diarrhoea 0% - 18.8% 17.1% x x x x x x x
Dizziness 0% - 19.6% 0% - 13.8% x x x x x x x x x x
Nausea 0% - 28.4% 2.86% - 11.6% x x x x x x x x x x
Sinusitis 3.1% - 8.33% 5.71% x x x x x x x
Chills 0% - 11.4% 11.4% x x x x x x x
Oedema peripheral 0% - 34.2% 0% - 24.6% x x x x x x x x x
Accidental injury 0% - 5.6% 2.86% x x x x x x x
Rhinitis 0% - 11.4% 11.4% x x x x x x x
Neutropenia postmarketing, 0.98% - 42.7% 1.29% - 2.59% x x x x x x x x x
Skin exfoliation 0% - 30.4% x x
Neuropathy peripheral 3.42% 0% x x x x x x x x x x
Abdominal pain 2.78% - 4.17% 11.4% x x x x x x x
Albuminuria 0% - 8.33% 5.71% x x x x x x x
Nail disorder 0% - 4.2% 0% x x x x x x x
Bronchopneumonia 2.99% 1.29% x
Anxiety 0% - 25.5% 1.29% - 9.48% x x x x x x x x
Neuropathy 0% - 53.9% 0% x x x x x x x x x x
Anorexia 0% - 28.4% 5.71% x x x x x x x
Aspartate aminotransferase increased 0% - 12.5% 5.71% x x x x x x x
Erectile dysfunction 0% - 8.33% 0% x x x x x x x
Myocardial ischaemia 2.56% 0.862% x
Ear and labyrinth disorders 2.56% 0% x x
Arthralgia 0% - 12.7% x x
Depression 0% - 23.5% 8.19% x x x x
Hyponatraemia postmarketing, 1.96% - 48% x x x x
Weight decreased 0% - 22.5% x x
Vomiting 0% - 11.8% x x x x x x x x x
Cerebrovascular accident postmarketing, 2.56% 0.431% x x x x x x x x x
Dyspepsia 0% - 18.6% 9.05% x x x x x x x x x
Hyperkalaemia postmarketing, 0% - 19.6% x x x x x x x
Hypokalaemia postmarketing, 0% - 22.5% 1.29% x x x x
Weight increased 0% - 21.6% 1.72% x x x x x x x
Lightheadedness 0% - 19.6% x x
Myalgia 0% - 16.7% x x x x x x x
Amenorrhoea postmarketing x x x x x x x x x x
Angioedema postmarketing x x x x x x x x x
Arrhythmia postmarketing x x x x x x x x x
Atrial fibrillation postmarketing, 4.7% 3.45% x x x x x x x x
Breast disorder postmarketing x x
Cholestasis postmarketing x x x x x x x
Deafness postmarketing x x x x x x x x
Diplopia postmarketing x x x x x x x
Enuresis postmarketing x x x x x x x
Toxic epidermal necrolysis postmarketing x x x x
Grand mal convulsion postmarketing x x x
Erythema multiforme postmarketing x x x x
Erythema nodosum postmarketing x x x x x x x
Gastrointestinal haemorrhage postmarketing x x x x x x x x x
Gynaecomastia postmarketing x x x x x x x
Hodgkin's disease postmarketing x x x x x x x
Hypercalcaemia postmarketing x x x x
Hypersensitivity postmarketing x x x x x x x x x
Hypothyroidism postmarketing x x x x x x x x x x
Immune system disorder postmarketing x
Intestinal obstruction postmarketing x x x x x x x x x
Intestinal perforation postmarketing x x x x
Renal failure acute postmarketing x x x x x x x
Labyrinthine disorder postmarketing x
Lethargy postmarketing x x x x x
Erythroleukaemia postmarketing x x x x x x x
Chronic myeloid leukaemia postmarketing x x x x x x x
Liver disorder postmarketing x x
Lymphoedema postmarketing x x x x x x x
Menstrual disorder postmarketing x x
Metrorrhagia postmarketing x x x x x x x
Myocardial infarction postmarketing x x x x x x x x x
Myxoedema postmarketing x x x x x x x
Nystagmus postmarketing x x x x x x x
Oliguria postmarketing x x x x x x x
Pancytopenia postmarketing x x x x x x x x x
Parkinson's disease postmarketing x x
Petechiae postmarketing x x x x x x x
Pleural effusion postmarketing x x x x
Purpura postmarketing x x x x x x x
Renal failure postmarketing x x
Convulsion postmarketing x x x x x x
Septic shock postmarketing x x x
Sick sinus syndrome postmarketing x x x x
Status epilepticus postmarketing x
Gastric ulcer postmarketing x x x x x x x
Aphthous stomatitis postmarketing x x x x x x x
Suicide attempt postmarketing x x x x x x x
Syncope postmarketing, 3.42% 0.431% x x x x x x x x x
Tachycardia postmarketing x x x x x x x x
Tumour lysis syndrome postmarketing x x x x x x
Loss of consciousness postmarketing x x x x
Urinary tract disorder postmarketing x
Urticaria postmarketing x x x x x x x x x
Stupor postmarketing x x x x
Footdrop postmarketing x x x x x x x
Migraine postmarketing x x x x x x x
Gastrointestinal perforation postmarketing x
Hypomagnesaemia postmarketing x x x x x x x
Liver function test abnormal postmarketing x
Phosphatase alkaline increased postmarketing x x x x x x x
Interstitial lung disease postmarketing x x x
Hangover postmarketing x x x x x x x
Consciousness abnormal postmarketing x x x x
Galactorrhoea postmarketing x x x x x x x
Sepsis postmarketing x x x x x x x x x
Electrolyte imbalance postmarketing x x x x
Dysaesthesia postmarketing x x x x x x x x x
Bradycardia postmarketing x x x x x x x x x
Sexual dysfunction postmarketing x x x
Mental status changes postmarketing x x x x
White blood cell count low postmarketing x x x x
Hearing impaired postmarketing x x
Multiple congenital abnormalities 0% - 9.4% 0% x x x x x x
Acquired immunodeficiency syndrome x x x x x x x
Agranulocytosis x x x x x x x
Alopecia x x x x x x x
Amblyopia x x x x x x x
Amnesia x x x x x x x
Amyloidosis x x x x x x x
Aplastic anaemia x x x x x x x
Hypochromic anaemia x x x x x x x
Anaemia macrocytic x x x x x x x
Anaemia megaloblastic x x x x x x x
Angina pectoris x x x x x x x
Apnoea x x x x x x x
Arthritis x x x x x x x
Ascites x x x x x x x
Ataxia x x x x x x x x x
Atrioventricular block x
Benign neoplasm of skin x x x x x x x
Bone disorder x
Bronchospasm x
Bronchitis x x x x x x x x x
Candida infection x x x x x x x
Causalgia x x x x x x x
Cellulitis x x x x x x x
Transient ischaemic attack x
Neck pain 0% - 4.2% 0% x x x x x x x
Chest pain x x x x x x x
Cholangitis x x x x x x x
Colitis x x x x x x x
Conjunctivitis x x x x x x x
Cough 0% - 18.6% x x x x x x x
Cyanosis x x x x x x x
Libido decreased x x x x x x x x
Dysphagia x x x x x x x
Dehydration x x x x x x x
Demyelination x
Dermatitis exfoliative x x x x x x x
Diabetes mellitus x x x x x x x
Drowsiness x x x x x x x x
Dysgeusia x x x x x x x
Dyskinesia x x x x x x x
Eczema x x x x x x x
Eosinophilia x x x x x x x x
Epistaxis x x x x x x x
Eructation x x x x x x x
Oesophagitis x x x x x x x
Eye disorder x x x x x x x x
Flatulence 0% - 8.33% 5.71% x x x x x x x
Gastroenteritis x x x x x x x
Gingival disorder x x x x x x x
Cardiac arrest x x x x x x x
Cardiac failure x x x x x x x x x
Cardiac failure congestive x x x x x x x
Blood disorder x x
Haematuria 0% - 11.1% 2.86% x x x x x x x
Hepatitis x x x x x x x x
Hepatomegaly x x x x x x x
Hernia x x x x x x x
Herpes simplex x x x x x x x
Hostility x x x x x x x
Hyperbilirubinaemia x x x x x x x
Hypercholesterolaemia x x x x x x x
Hyperaesthesia x x x x x x x
Hypoaesthesia x
Hypoglycaemia x x x x x x
Hypoproteinaemia x x x x x x x
Orthostatic hypotension x x x x x x x x x
Ichthyosis x x x x x x x
Inappropriate antidiuretic hormone secretion x x x x x x x
Influenza x x x x x x x
Jaundice cholestatic x x x x x x x
Arthropathy x x x x x x x
Lacrimal disorder x x x x x x x
Cramps of lower extremities x x x x x x x
Leukaemia x x x x x x x
Acute myeloid leukaemia x
Leukocytosis x x x x x x x
Lung disorder x x x x x x x
Meningitis x x x x x x x
Menopause x
Cramp muscle x x
Hypertonia x x x x x x x
Myelodysplastic syndrome x
Nervousness 0% - 9.4% 0% x x x x x x x
Neuralgia x x x x x x x
Neuritis x x x x x x x
Numbness x
Orchitis x x x x x x x
Palpitations x x x x x x x
Pancreatitis x x x x x x x x
Pericarditis x x x x x x x
Periodontitis x x x x x x x
Peritonitis x x x
Proteinuria x x x x x x x
Psoriasis x x x x x x x
Psychotic disorder x x x x x x x
Pulmonary oedema x x x x x x x
Emphysema x x x x x x x
Pyuria x x x x x x x
Rales x x x x x x x
Retinitis x x x x x x x
Seborrhoeic dermatitis x x x x x x x
Skin disorder x x x x x x x
Skin ulcer x
Stevens-Johnson syndrome x x x x x x x x x x
Stomatitis x x x x x x x
Sweating 0% - 12.5% 11.4% x x x x x x x
Thromboembolism x
Thrombophlebitis x x x x x x x
Tinnitus x x x x x x x
Tooth disorder x x x x x x x
Toothache 0% - 4.2% 0% x x x x x x x
Tremor 0% - 26.5% 0% - 12.5% x x x x x x x x x x
Upper respiratory tract infection x x x x x x x
Pollakiuria x x x x x x
Vasodilation x x x x x x x
Venous thrombosis x
Vertigo 0% - 8.33% 0% x x x x x x x x x
Viral infection x x x x x x x
Peripheral vascular disorder x x x x x x x
Microcytic anaemia x x x x x x x
Sinus bradycardia x
Burning sensation x
Hypoalgesia x x x x x x x
Agitation 0% - 25.5% 0% x x x x x x x
Mood swings x x x x x x x x x
Neck stiffness 0% - 4.2% 0% x x x x x x x
Hormone level abnormal x x x x x x x
Blood urea increased x x x x x x x
Creatinine increased x x x x x x x
Tongue discolouration x x x x x x x
Lactic dehydrogenase activity increased x x x x x x x
Skin necrosis x x x x x x x
Eye pain x x x x x x x
Circumoral paresthesia x x x x x x x
Disorder periosteal x x x x x x x
Vesiculobullous rash x x x x x x x
Hyporeflexia x x x x x x x
Alanine aminotransferase increased x x x x x x x
Skin discolouration x x x x x x x
Dry skin 0% - 20.6% x x x x x x x x x
Arterial thrombosis x
Polyneuropathy x
Photosensitivity reaction x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x x
Disability x
Malaise 0% - 8.33% 0% x x x x x x x x x
Increased appetite x x x x x x x x
Teratogenicity x x x x x x x x x x
Thinking abnormal x x x x x x x
Euphoric mood x x x x x x x
Bone tenderness x x x x x x x
Creatinine low x x x x x x x
Pain in arm x x x x x x x
Spleen palpable x x x x x x x
Disease progression x x x
Mental state abnormal x
Dry eye x x x x x x x
Anxiety depression x
Parotid gland enlargement x x x x x x x
Vision blurred x x x
Photosensitivity x x x x x x x x
Avitaminosis x x x x x x x
Enlargement abdomen x x x x x x x
Platelet count decreased x
Hyperkinesia x x x x x x x
Dementia x x x x x x x
Coordination abnormal x x x x x x x x x
Toxic skin eruption x x
Face oedema 0% - 4.2% 0% x x x x x x x
Visual disturbance x
Lipase increased x x x x x x x
Gait disturbance x x x x x x x
Drug interaction x x x x x x
Serum creatinine increased x x x x x x x
Acne 0% - 11.1% 0% x x x x x x x
Hyperuricaemia x x x x x x x
Diverticular perforation x x x
Thromboembolic event x x
Raised liver function tests x x x x x x x
Cerebral ischaemia x x x x x x x
Insomnia 0% - 47.1% 5.71% x x x x x x x x
Phosphorus low x x x x x x x
Myasthenia x x x x x x x
Bronchopneumopathy x x
Pneumocystis jirovecii pneumonia x x
Tingling sensation x
Mood alteration NOS x x
Posterior reversible encephalopathy syndrome x
Arterial thromboembolism x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Thalidomide

Side effects:41
Source:BC Cancer

thalidomide / thalidomide

Side effects:94
Source:EMA

Teratogenic effects: / THALOMID CAPSULES

Side effects:104
Source:medicines.org.au

THALIDOMIDE / THALOMID

Side effects:252
Source:FDA

thalidomide / Thalomid

Side effects:253
Source:FDA

thalidomide / Thalomid

Side effects:254
Source:FDA

THALIDOMIDE / THALOMID

Side effects:270
Source:FDA

thalidomide / Thalomid

Side effects:273
Source:FDA

THALIDOMIDE / THALOMID

Side effects:284
Source:FDA

THALIDOMIDE

Side effects:314
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label