Tapentadol

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Nausea def 21% - 30% 7% - 13% x x x x x x
Dizziness def 17% - 24% 7% - 8% x x x x x x
Vomiting def 8% - 18% 3% - 4% x x x x x x
Constipation def 8% - 17% 3% - 7% x x x x x
Headache def postmarketing, 15% 13% x x x x x x
Somnolence def 12% - 15% 3% - 4% x x x x x x
Fatigue def 3% - 9% 1% - 4% x x x x x
Dry mouth def 4% - 7% 1% - 3% x x x x x
Hyperhidrosis def 3% - 5% 1% x x x x x
Pruritus def 3% - 5% 1% - 2% x x x x x
Insomnia def 2% - 4% 1% - 2% x x x x x
Dyspepsia def 2% - 3% 1% - 2% x x x x x
Pruritus generalised 3% 1% x x x x
Anxiety def 1% - 2% 1% x x x x x
Asthenia def 2% 1% x
Flushing def 1% - 2% 0% - 1% x x x x x
Lethargy def 1% - 2% 0% - 1% x x x x x
Vertigo def 2% 1% x
Decreased appetite 2% 0% - 1% x x x x x
Hot flush def 1% - 2% 0% - 1% x x x x x
Arthralgia def 1% 1% x x x x
Confusional state def 1% 0% x x x x x
Dyspnoea def 1% 1% x x x x x
Rash def 1% 1% x x x x x
Infection def 1% 1% x x x x
Nasopharyngitis def 1% 1% x x x x
Respiratory tract infection def 1% 1% x x x x
Tremor def 1% 0% - 1% x x x x x
Upper respiratory tract infection def 1% 1% x x x x
Urinary tract infection def 1% 1% x x x x
Chills def 1% 0% x
Disturbance in attention 1% 0% x x x x x
Abnormal dreams 1% 0% - 1% x x x x x
Erectile dysfunction def 1% 0% x
Vision blurred def 1% 0% x
Depressed mood def 1% 1% x
Feeling hot 1% 1% x x x x
Angioedema def postmarketing x x x
Mental disorder def postmarketing x x x x x
Diarrhoea def postmarketing x x x
Gastrointestinal disorder def postmarketing x x x x x
Hallucination def postmarketing x x x x
Cardiac disorder def postmarketing x x x x x
Immune system disorder def postmarketing x x x x x
Nervous system disorder def postmarketing x x x x x
Palpitations def postmarketing x x
Suicidal ideation def postmarketing x
Alcohol intoxication def x x x x x
Ataxia def x x x x
Back pain def x
Breast disorder def x
Connective tissue disorder def x x x x
Cough def x x x x
Drug hypersensitivity def x
Dysarthria def x x x x x
Oedema def x x x x
Eye disorder def x x x x x
Hypersensitivity def x x x x x
Hypoaesthesia def x x x x x
Hypotension def x x x x x
Irritability def x x x x x
Low back pain def x
Mediastinal disorder def x x x x x
Nervousness def x x x x
Osteoarthritis def x
Paraesthesia def x x x x x
Neuropathy peripheral def x
Seizures def x x x x x
Withdrawal syndrome def x x x x x
Syncope def x x x x x
Tachycardia def x x x x x
Pollakiuria def x x x x x
Urinary tract disorder def x x x x x
Urticaria def x x x x x
Angiopathy def x x x x x
Weight decreased def x
Agitation def x x x x x
CNS depression NOS x x x x x x
Aspartate aminotransferase increased def x x x x
Alanine aminotransferase increased def x x x x
Urinary hesitation x x x x x
Drug withdrawal syndrome def x x x x x
Abdominal discomfort x x x x
Disorientation x x x x x
Thinking abnormal x x x x x
Perceptual disturbance x
Memory impairment def x x x x x
Discomfort def x x x x
Respiratory depression x x x x x x
Muscle contractions involuntary x x x x
Euphoric mood def x x x x x
Bradycardia def x x x x x
Neuropathy def x
Coordination abnormal x x x x x
Impaired gastric emptying x x x x x
Feeling drunk x x x x x
Visual disturbance x x x x x
Depressed level of consciousness def x x x x x
Sexual dysfunction x
Balance disorder x
Sensation of heaviness x x x x
Sedation x x x x x
Presyncope def x x x x x
Dissecting aortic aneurysm, thoracic x x x x x
Diabetic peripheral neuropathy x
Oxygen saturation decreased def x x x x
Infestation NOS x x x x
Mental disability x
Feeling abnormal x
Drug dependence def x
Indication Labels
Acute pain def x x x x x
Chronic pain def x
Pain def x x x x x x
Postoperative pain def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N02AX06

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. TAPENTADOL : 7 side effects (FDA XML label)
  2. tapentadol : 84 side effects (FDA XML label)
  3. TAPENTADOL : 85 side effects (FDA XML label)
  4. TAPENTADOL : 87 side effects (FDA XML label)
  5. tapentadol : 88 side effects (FDA XML label)
  6. tapentadol : 89 side effects (FDA XML label)