Alprazolam

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 30)
1 2 3 4 5 6 7 8 9 10
Drowsiness def 41% - 76.8% x x x x x x x x
Fatigue def 9.2% - 48.6% 9.2% x x x x x x x x
Sedation 22.6% - 45.2% 22.6% x x x x x x x x
Coordination abnormal 0.9% - 40.1% 0.9% x x x x x x x x
Memory impairment def 6.9% - 33.1% 6.9% x x x x x x x x x
Salivation def 4.2% - 32.8% x x x x x x x
Increased appetite 6% - 32.7% 6% x x x x x x x
Insomnia def frequent, 8.9% - 29.4% 9.6% x x x x x x x x
Headache def frequent, 12.6% - 29.2% 12.6% x x x x x x x x
Cognitive disorder def 28.8% x x x x x x x
Tremor def frequent, 4% - 28.2% 10.7% x x x x x x x
Decreased appetite 3.8% - 27.8% 3.8% - 7.2% x x x x x x x x
Weight increased def 2.7% - 27.2% 4.3% x x x x x x x x
Constipation def 4.3% - 26.2% 4.3% x x x x x x x x
Dysarthria def 2.6% - 23.3% 2.6% x x x x x x x x x
Somnolence def 6% - 23% 6% x
Weight decreased def 2.3% - 22.6% 3.7% x x x x x x x x
Vomiting def frequent, 9.6% - 22% x x x x x x x x
Nervousness def frequent, 4.1% - 21.8% 8.8% x x x x x x x
Vision blurred def frequent, 6.2% - 21% x x x x x x x x
Nasal congestion def frequent, 7.3% - 17.4% x x x x x x x x
Abnormal involuntary movements def 14.8% x x x x x x
Movements involuntary def 14.8% x x x x x x
Libido decreased def 2.3% - 14.4% 2.3% x x x x x x x x
Difficulty in micturition frequent, 12.2% x x x x x x x x
Rash def infrequent, 10.8% x x x x x x x x
Confusional state def 0.9% - 10.4% 0.9% x x x x x x x x
Menstrual disorder def 10.4% x x x x x x x
Hyperventilation def frequent, 2.7% - 9.7% 2.7% x x x x x x x x
Hypoaesthesia def 0.3% - 7.8% 0.3% - 2.3% x
Libido increased def frequent, 7.7% x x x x x x x x
Sexual dysfunction 1.1% - 7.4% 1.1% x x x x x x x x
Ataxia def 3.2% - 7.2% 3.2% x
Mental disability 5.7% - 7.2% 5.7% x
Weakness def frequent, 7.1% x x x x x x x x x
Tinnitus def infrequent, 6.6% x x x x x x x x
Salivary hypersecretion def infrequent, 4.2% - 5.6% x x x x x x x x
Abdominal pain def frequent x
Back pain def frequent x
Dyspepsia def frequent x
Cramp muscle def frequent, 2.4% x x x x x x x x
Nervous system disorder def frequent x
Nightmare def frequent x
Vertigo def frequent x
Malaise def frequent x
Sweating increased frequent x
Oedema def infrequent, 4.9% x x x x x x x x
Hypotension def infrequent, 4.7% x x x x x x x
Infection def 1.3% - 4.3% 1.7% x x x x x x x x
Respiratory tract infection def 1.7% - 4.3% 1.7% x x x x x x x x
Upper respiratory tract infection def 1.7% - 4.3% 1.7% x x x x x x x x
Muscle rigidity def 4.2% x x x x x x
Dermatitis def 3.8% x x x x x x
Hypersensitivity def 3.8% x x x x x x
Dysmenorrhoea def 2.9% - 3.6% 2.9% x
Disturbance in attention 0.6% - 3.2% 0.6% x
Pharyngolaryngeal pain def 2.6% - 3.2% 2.6% x
Akathisia def 1.6% - 3% x x x x x x x
Disinhibition 2.7% x x x x x x x
Arthralgia def 0.6% - 2.4% 0.6% x
Influenza def 2.3% - 2.4% 2.3% x
Muscle stiffness 2.2% x x x x x x x
Stiffness 2.2% x x x x x x x
Talkativeness 2.2% x x x x x x x
Dyskinesia def 1.4% - 1.7% 1.4% x
Lethargy def 0.6% - 1.7% 0.6% x
Premenstrual syndrome def 0.6% - 1.7% 0.6% x
Anorexia def 0% - 1.5% 0% x x x x x x x x
Incontinence def infrequent, 1.5% x x x x x x x x x
Myalgia def 1.1% - 1.5% 1.1% x
Disorientation 0% - 1.5% 0% x
Depressed mood def 0.3% - 1.3% 0.3% x
Hypersomnia def 0% - 1.3% 0% x
Pain in extremity def 0.3% - 1.1% 0.3% x
Pruritus def 0.9% - 1.1% 0.9% x x x x x x x x
Rhinitis def 0.6% - 1.1% 0.6% x
Rhinitis allergic def 0.6% - 1.1% 0.6% x
Aggression def postmarketing, infrequent x x x x x x x x x
Alcohol intoxication def infrequent x
Anger def infrequent x
Asthenia def infrequent x
Connective tissue disorder def infrequent x
Dysphagia def infrequent x
Ear pain def infrequent x
Epistaxis def infrequent x
Eye disorder def infrequent x
Body temperature increased def infrequent x
Gastrointestinal disorder def infrequent x x x
Hallucination def postmarketing, infrequent x x x x x x x x x x
Mediastinal disorder def infrequent x
Mydriasis def infrequent
Sinus tachycardia def infrequent x
Thirst def infrequent x
Urinary incontinence def infrequent x
Urinary tract disorder def infrequent x
Urticaria def infrequent x
Angiopathy def infrequent x
Apathy def infrequent x
Mood swings infrequent x
Photophobia def infrequent x
Hangover infrequent x
Chest tightness infrequent x
Logorrhoea infrequent x
Abnormal dreams infrequent x
Euphoric mood def infrequent x
Hypomania def infrequent x x x
Mania def infrequent x x x
Suicidal ideation def infrequent x x
Psychomotor retardation infrequent x
Rigors infrequent x
Homicidal ideation infrequent x
Energy increased infrequent x
Feeling drunk infrequent x
Feeling hot and cold infrequent x
Choking sensation infrequent x
Feeling jittery infrequent x
Bradyphrenia infrequent x
Dissecting aortic aneurysm, thoracic infrequent x
Sluggishness infrequent x
Rhinorrhoea def infrequent x
Dysphonia def infrequent x
Feeling hot infrequent x
Borderline personality disorder def postmarketing x x x x x x x x x
Gynaecomastia def postmarketing x x x x x x x x x
Hepatitis def postmarketing x x x x x x x x x
Hostility def postmarketing x x x x x x x x x
Hyperprolactinaemia def postmarketing x x x x x x x x x x
Muscle spasticity def postmarketing x x x x x x x x x
Personality disorder def postmarketing x x x x x x x x x
Rage def postmarketing x x x x x x x x x
Sleep disturbance postmarketing x x x x x x x x x
Post-traumatic stress disorder def postmarketing x x x x x x x
Withdrawal syndrome def postmarketing x x x x x x x
Hepatic failure def postmarketing x x x x x x x x x
Galactorrhoea postmarketing x x x x x x x x x
Violent postmarketing x x x x x x x x x
Substance abuse def postmarketing x x x x x x x x x
Amnesia def x x x x x x x x
Angioedema def x x
Apnoea def x
Breast disorder def x
Convulsion def
Depressive disorder def x x x x x x x
Diplopia def x x x x x x x x x
Drug abuse def
Epilepsy def
Cardiac disorder def x
Jaundice def x x x x x x x x x
Hypotonia def x
Seizures def x x x x x x x x x x
Sleep apnoea syndrome def x
Stevens-Johnson syndrome def x
Suicide def x x x x x x x
Urinary retention def x x x x x x x
Addiction def
Stupor def x
Oedema peripheral def x x
Hepatic function abnormal x
Muscular weakness def
Menstruation irregular def x x x x x x x
Dysphoria
Amnesia transient x x x x x x x
Clumsiness x
Slurred speech x x x x x x x
Intraocular pressure increased x
Withdrawal seizures x x x x x x x x
Cerebration impaired def x x x x x x x
Hepatic enzyme increased x x x x x x x
Dependence psychological def
Blood bilirubin increased def x x x x x x
Dystonia def x x x x x x x
Sleep talking x
Depressed level of consciousness def x
Infestation NOS x
Anxiety symptoms NOS x x x x x x x
Major depression def x x x x x x x
Indication Labels
Abdominal distress x x x x x x x x x x
Ache def x x x x x x x
Agitation def x x x x x x x
Agoraphobia def x x x x x x x x x
Anxiety def x x x x x x x x x
Anxiety disorder def x x x x x x x x x
Chest pain def x x x x x x x x x
Chills def x x x x x x x x x x
Choking def x x x x x x x x x
Depersonalisation def x x x x x x x x x
Derealisation def x x x x x x x x x
Diarrhoea def x x x x x x x
Discomfort def x x x x x x x x x
Dizziness def x x x x x x x x x x
Dry mouth def x x x x x x x
Dyspnoea def x x x x x x x x x x
Exaggerated startle response x x x x x x x
Fatigability x x x x x x x
Fear x x x x x x x x x
Fear of death x x x x x x x x x
Flushing def x x x x x x x x x x
Generalised anxiety disorder def x x x x x x x
Heart pounding x x x x x x x
Hot flush def x x x x x x x x
Hyperkinesia def x x x x x x x
Irritability def x x x x x x x
Lightheadedness x x x x x x x x x
Mass def x x x x x x x
Mental disorder def x x x x x x x
Muscle tension x x x x x x x
Muscle twitching def x x x x x x x
Nausea def x x x x x x x x x x
Numbness def x x x x x x x
Pain def x x x x x x x x x
Palpitations def x x x x x x x x x x
Panic attack def x x x x x x x x
Panic disorder def x x x x x x x x x
Panic reaction def x x x x x x x x x
Paraesthesia def x x x x x x x x x
Phobia def x x
Pollakiuria def x x x x x x
Shakiness x x x x x x x
Sickness x x
Social phobia def x x
Sticky skin x x x x x x x
Sweating def x x x x x x x x x x
Syncope def x x
Tachycardia def x x
Tenderness def x x x x x x x
Tension def x x x x x x x
Tingling sensation def x x x x x x x
Toxic epidermal necrolysis def x x
Trembling x x x x x x x x x x
Unsteadiness x x x x x x x
Worry def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N05BA12

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. ALPRAZOLAM : 28 side effects (FDA XML label)
  2. ALPRAZOLAM : 38 side effects (FDA XML label)
  3. Alprazolam : 53 side effects (FDA XML label)
  4. ALPRAZOLAM / XANAX TAB 1MG : 71 side effects (Health Canada)
  5. ALPRAZOLAM / NIRAVAM : 83 side effects (Drugs@FDA)
  6. ALPRAZOLAM : 84 side effects (FDA XML label)
  7. ALPRAZOLAM : 84 side effects (FDA XML label)
  8. ALPRAZOLAM : 88 side effects (FDA XML label)
  9. ALPRAZOLAM : 89 side effects (FDA XML label)
  10. alprazolam : 135 side effects (FDA XML label)