Search results :

Methotrexate

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: L01BA01, L04AX03

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Alopecia 1-10% x x x x x x x x x x
Exanthema 1-10% x x x x x x x x x x
Photosensitivity of skin 1-10% x x x x x x x x x
Myalgia 1-10% x x x x x x x x x x
Diabetes Mellitus 1-10% x x x x x x x x x
Dizziness 1-10% x x x x x x x x x
Vasculitis 1-10% x x x x x x x x x x
Malaise 1-10% x x x x x x x x x
Blurred vision 1-10% x x x x x x x x x
Seizures 1-10% x x x x x x x x x x
Pulmonary toxicity 2-8% x x x
anaphylaxis 1% x x x
Anaphylactoid reaction x x x x x x x
Hepatitis, Chronic x
Aseptic necrosis x
Ear and labyrinth disorders x
Pneumonia, Interstitial x x x x x x x
Kidney Diseases x x x x x x x x
Pulmonary Embolism x x x x x x x x x x
Impaired healing x
Guillain-Barre Syndrome
Lymphoproliferative Disorders x x x x x
Enteritis x x x x x x x x x
Herpes Simplex Infections x
Liver Failure x x x
Rales x
Hypersensitivity x x x
Respiratory Failure x x x x
Neurotoxicity Syndromes
Communicable Diseases x x x x x x x x x
Lethargy x x
Abdominal Pain x
Necrolysis epidermal
Thrombosis of retinal vein x x x x x x x x x x
Ocular discomfort x x x x x x x
Motor dysfunction x
Extravasation x
Lung fibrosis interstitial x
Breast Diseases x
Tinnitus x x x x x x x
Raised liver function tests x x x x x
Vascular Diseases x
Abdominal discomfort x
Azotemia x x x x x x x x x x
Asthenia x
Anuria x
Cerebral Thrombosis x x x x x x x x x x
Arthralgia x x x x x x x x x x
Stomatitis x x x x x x x x x x
Cytomegaloviral pneumonia x x
Urologic Diseases x
Pancreatitis x x x x x x x x x
Pleurisy
Pericardial effusion x x x x x x x x x x
Hepatic Insufficiency x
Liver Cirrhosis x x
Bone necrosis x x x x x x x
Infection by Cryptococcus neoformans x x x x x x x
Pericarditis x x x x x x x x x x
Carcinogenicity x
Kidney Failure x x x x x x x x x
Burning sensation x
Vasculitis, Leukocytoclastic, Cutaneous x
Encephalopathies x x x x x x x x x
Pneumocystis jiroveci pneumonia x x x x x x x
Nodule x
Pharyngitis x x x x x x x x x x
Immune System Diseases x
Meningism x
Stevens-Johnson Syndrome x x x x x x x x x x
Bone marrow depression x x
Inflammation x
Coughing x x x x x x x
Erythema x x
Ataxia x
Fibrosis x x x x x x x x
Herpes simplex hepatitis x
Pulmonary Edema x
Psoriatic plaque x x x
Lymphadenopathy x x x x x x
Dysarthria x x x x x x
Hypoxemia x
Skin Ulcer x x x x x
Gastrointestinal Diseases x
Hypervigilance x
Pain x x
Vaginal Discharge x x x x x x x x x x
Diarrhea x x x x x x x x x x
Aplastic Anemia x x x x x x x
Comatose x x
nervous system disorder x
Thrombophlebitis x x x x x x x x
Cystitis x x x x x x x x
Disturbance in mood x x x x x x x x x
Septicemia x
Urine volume finding x
Exfoliative dermatitis x x x x x x x x x
Visual Impairment x
Anemia x x x x x x x x x
Osteoporosis x x x x x x x x x
Opportunistic Infections x x x x x x x x x
Back Pain x
Pruritus x x x x x x x x x x
Mental Depression x
Mucositis x
Lung infiltration x
Anemia, Megaloblastic x x
Vertigo x
Dry cough x
Spinal Cord Diseases x
Soft tissue necrosis x x x x x x x
Serum albumin low result x x x x x
Dermatitis x x x x x x x x x
Intestinal Perforation x
Chest Pain x x x x x x x
Hemorrhage x x x
Scalding injury x x x x
Blood and lymphatic system disorders x x x x x
Heart Diseases x
Hematocrit decreased x x x x x
Eruptions x
Confusion x x x
Infestation x
Furunculosis x x x x x x x x x x
Proteinuria x x x x
Cyst x
Chronic Obstructive Airway Disease x
Fibrosis, Liver x
Pulmonary Fibrosis x x
Thrombocytopenia x x x x x x x
Hepatic atrophy x
Upper Respiratory Infections x x x x x
Gastrointestinal toxicity x
Mediastinal Diseases x
Pancytopenia x x x x x x x x
Anorexia x x x x x x x x x
Lung diseases x x
Gynecomastia x x x x x x x x x
Aphasia x x x x x x x x
Drowsiness x x x x x x x x x
Neck stiffness x
Mental disorders x
Apnea x
Abscess x
Skin and subcutaneous tissue disorders x
Eosinophilia x x x x
Retinal Diseases x
Seizures, Focal
Sepsis x x x x x x x
Lack of libido x x x x x x x x x x
Nausea x x x x x x x x x x
Dementia x x
Vomiting x x x x x x x x x x
Disorder of eye x x
Hidradenitis x
Arachnoiditis x
Chronic liver disease
Chills x x x x x x x x x
Hyperbilirubinemia x
Hepatitis x x x x x x x
Hyperuricemia x
Folliculitis x x
Aseptic Meningitis x x
Glossitis x x
Arterial thrombosis x x x x x x x x
Deep Vein Thrombosis x x x x x x x x x x
Reaction gastrointestinal x x x x
Malabsorption Syndrome x x
Nail changes x
Loss of appetite (finding) x
Ecchymosis x x x x x x x x x x
Malnutrition x
Hypopigmentation disorder
Febrile Neutropenia x
Stupor
Urticaria x x x x x x x x x
Stress Fractures x x x x x x x
Hematemesis x x x x x x x x x x
Tumor Lysis Syndrome x x x x x x x x
Pleural effusion disorder x x
Abdominal distress x x x x x x x x
Burkitt Lymphoma x
Cranial nerve palsies x
Leukoencephalopathies x x x x x x x
Neurologic Deficits x
Asthma x
Megacolon, Toxic x x
Speech impairment x x x x x
Agranulocytosis x x x x
Hyperpigmentation x
Polyuria x
Dyspnea x x x
Fracture x
Lung infection x
Neoplasms x x
Somnolence x
Dyspepsia x
Sweating x x x x x
Nuchal Rigidity
Oliguria x
Thromboembolic event x x x x x x x x x
Radiodermatitis x
Paraplegia
Petechiae x x x
Telangiectasis x x x x x x x x x x
Hepatitis acute x x x x x
Sleeplessness x
Radiculopathy x
Nocardia Infections x x x x x x x x
Cytomegalovirus Infections x x
Extrinsic allergic alveolitis x
Herpes zoster disease x x x x x x x x
Hypotension x x x x x x x x x x
Conjunctivitis x x x x x x x x
polyps x
Pneumonia x x x x x x
Erythema Multiforme x x x x x x x x x x
Necrosis x
Cyanosis x
Impaired cognition x x x x x x x x x
Fatigue x x x x x x x x x x
leukemia x
Achromia of skin x
Hematuria x x x x x x x x x x
Hepatobiliary disease x x x
Infertility x x x x x x x x x
Erectile dysfunction x x x x x x x x x x
Hepatotoxicity x x x x x x x
Fever x x x x x x x x x x
Paralysed x
Alveolitis x x x
Neutropenia x x x x x x
Sunburn x
Blindness, Transient x x x x x
Toxic Epidermal Necrolysis x x x x x x x x x
Gingivitis x x x x x x x x x x
Ureteral obstruction x
Immunologic Deficiency Syndromes
Bone Diseases x x
Paronychia Inflammation x
Kidney Failure, Acute x
Paresis x x x x x x x
Cerebrovascular accident x
Taste, Metallic x
Vaginitis x
Irritable Mood x
Gastrointestinal ulcer x
Bacterial Infections
Epistaxis x x x x
Leukopenia x x x x x x x x
Hypogammaglobulinemia x x x x x x x
Ulcerative stomatitis x x x x x x x
Headache x x x x x x x x x x
Hemiparesis x x x x x x x x x
Mycoses x
CNS toxicity
Melena x x x x x x x x x
Sudden death x x x x x x x x x
Dysuria x x x x x x x x
Skin necrosis x x x x x x x x
Oligospermia x x x x x x x x x
Fetal Death x x x
Cardiac Tamponade x
Pulmonary lymphoma x
Hepatic enzyme increased x x
Lung Diseases, Obstructive x x x x x x x
Visual disturbance x
Paresthesia of limbs x
Gastrointestinal ulcer haemorrhage x x x x x x x
Diabetic x
Histoplasmosis x x x x x x x
Ulcer x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

METHOTREXATE (METHOTREXATE SODIUM) / METOJECT

Side effects:91
Source:Health Canada

formerly Amethopterine / Methotrexate

Side effects:98
Source:FDA

methotrexate

Side effects:113
Source:FDA Structured Product Label

Methotrexate

Side effects:116
Source:BC Cancer

METHOTREXATE

Side effects:117
Source:FDA Structured Product Label

METHOTREXATE

Side effects:119
Source:FDA Structured Product Label

Methotrexate tablets / Methoblastin, Tablet

Side effects:127
Source:Medsafe

METHOTREXATE

Side effects:128
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label