Gefitinib

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Angioedema def postmarketing x x x x x x
Cough def postmarketing x x x x x x x
Dyspnoea def postmarketing x x x x x x x
Toxic epidermal necrolysis def postmarketing x x x x x
Epistaxis def postmarketing x x x x x
Erythema multiforme def postmarketing x x x x x x
Body temperature increased def postmarketing x x x x x x x
Fibrosis def postmarketing x x x x x x
Haematuria def postmarketing x x x x x
Haemorrhage def postmarketing x x x x x x x
Hypersensitivity def postmarketing x x x x x
Ischaemia def postmarketing x x x x x
Lung disorder def postmarketing x x x x x x x
Pain def postmarketing x x x x x x x
Pancreatitis def postmarketing x x x x x x
Pneumonia def postmarketing x x x x x x x
Pulmonary fibrosis def postmarketing x x x x x x
Ulcer def postmarketing x x x x x x
Erythema def postmarketing x x x x x x
Urticaria def postmarketing x x x x x x
Necrolysis epidermal postmarketing x x x x x x
Eye pain def postmarketing x x x x x
Interstitial pneumonia postmarketing x x x x x x x
Interstitial lung disease def postmarketing x x x x x x x
Corneal erosion postmarketing x x x x x x
Alveolitis postmarketing x x x x x
Drug interaction def postmarketing x x x x x
Dissecting aortic aneurysm, thoracic postmarketing x
Pulmonary toxicity postmarketing x x x x x
Idiopathic pulmonary fibrosis def postmarketing x x x x x x
Abdominal pain def x x
Alopecia def x
Amblyopia def x x x x x
Anaemia def x
Anorexia def x x x x x x x
Arrhythmia def x
Asthenia def x x x x x x x
Atrial fibrillation def x x
Blepharitis def x x
Bundle branch block def x x
Conjunctivitis def x x x x x x x
Constipation def x x
Dehydration def x x
Dermatitis def x x
Dermatitis exfoliative def x x
Diarrhoea def x x x x x x x
Oedema def x x x x x x x
Effusion def x
Rash def x x x x x x x
Fatigue def x
Gastrointestinal disorder def x
Gastrointestinal haemorrhage def x
Cardiac disorder def x
Haemoptysis def x
Hypokalaemia def x x
Hypotension def x
Infection def x
Mediastinal disorder def x
Melaena def x
Nail disorder def x x
Nausea def x x x x x x x
Neutropenia def x
Paronychia def x
Pleural disorder def x
Pleural effusion def x
Pneumoconiosis def x
Pruritus def x x x x x x x
Rectal disorder def x x
Seborrhoeic dermatitis def x x
Shock def x
Stomatitis def x x
Thrombocytopenia def x x
Thrombophlebitis def x
Angiopathy def x
Vomiting def x x x x x x x
Weight decreased def x x x x x x x
Rash pustular def x
Oedema peripheral def x x x x x x x
Mouth ulceration def x x x x x x
Scrotal oedema x x
Pulmonary haemorrhage def x
Hypomagnesaemia def x
Electrocardiogram QT prolonged def x
Vesiculobullous rash x x x x x
Aspartate aminotransferase increased def x x
Alanine aminotransferase increased def x x
Dry skin def x x x x x x x
Deep thrombophlebitis x
Cardiac fibrillation x x
Hypoxia def x
Conduction disorder def x
Eruption x
Sinoatrial node dysfunction def x
Cancer pain def x
Acne def x x x x x x x
Febrile neutropenia def x
Infestation NOS x
Electrocardiogram QT corrected interval prolonged def x
Respiratory failure def x
Electrolyte disturbance x
Indication Labels
Lung neoplasm malignant def x x x x x x x
Neoplasm def x
Neoplasm malignant def x x x x x x x
Non-small cell lung cancer def x x
Small cell lung cancer stage unspecified def x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XE02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. GEFITINIB / IRESSA : 43 side effects (Drugs@FDA)
  2. gefitinib tablets / Iressa : 43 side effects (FDA MedWatch)
  3. GEFITINIB / IRESSA : 45 side effects (Drugs@FDA)
  4. GEFITINIB : 45 side effects (FDA XML label)
  5. gefitinib tablets / Iressa : 45 side effects (FDA MedWatch)
  6. Gefitinib : 61 side effects (BC Cancer)
  7. GEFITINIB / IRESSA : 72 side effects (Health Canada)