Fludarabine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 14)
1 2 3 4 5 6 7 8 9 10
Asthenia def 13% - 31% x
Fatigue def postmarketing, 13% - 31% x x x x x x x x x x
Weakness def postmarketing, 13% - 31% x x x x x x x x x x
Body temperature increased def postmarketing, 11% - 26% x x x x x x x x x x
Cough def postmarketing, 0% - 21% x x x x x x x x x x
Anorexia def postmarketing, 0% - 19% x x x x x x x x x x
Pain def postmarketing, 0% - 19% x x x x x x x x x
Infection def postmarketing, 4% - 17% x x x x x x x x x x
Respiratory tract infection def postmarketing, 9% - 14% x x x x x x x x
Sweating def 0% - 14% x
Upper respiratory tract infection def postmarketing, 9% - 14% x x x x x x x x
Sweating increased postmarketing, 0% - 14% x x x x x x x x
Rhinitis def 3% - 11% x
Abdominal pain def 8% - 10% x
Back pain def 4% - 9% x
Bronchitis def postmarketing, 6% - 9% x x x x x x x x
Headache def postmarketing, 9% x x x x x x x x
Herpes NOS def postmarketing, 7% - 8% x x x x x
Herpes simplex def 7% - 8% x
Influenza def 5% - 8% x
Pneumonia def postmarketing, 3% - 8% x x x x x x x x x x
Oedema def postmarketing, 0% - 7% x x x x x x x x x x
Oedema peripheral def 0% - 7% x
Diarrhoea def postmarketing, 5% - 6% x x x x x x x x x x
Skin disorder def postmarketing, 0% - 6% x
Weight decreased def 1% - 6% x
Lactic dehydrogenase activity increased 0% - 6% x
Cough increased 0% - 6% x
Chest pain def 0% - 5% x
Dyspnoea def postmarketing, 1% - 5% x x x x x x x x x
Rash def postmarketing, 4% - 5% x x x x x x x x x x
Nausea def postmarketing, 1% - 5% x x x x x x x x x x
Sinusitis def postmarketing, 1% - 5% x x x x x x x x
Urinary tract infection def postmarketing, 4% - 5% x x x x x x x x
Acidosis def postmarketing x x x x x x x x
Alopecia def postmarketing x x x x x x x
Alveolitis allergic def postmarketing x x x x x x x
Anaphylactic shock def postmarketing x x x x x x x
Anaemia def postmarketing x x x x x x x x
Haemolytic anaemia def postmarketing x x x x x x x x
Anaemia haemolytic autoimmune def postmarketing x x x x x x
Aneurysm def postmarketing x x x x x x x
Angina pectoris def postmarketing x x x x x x x
Arrhythmia def postmarketing x x x x x x x x x
Arthralgia def postmarketing x x x x x x x
Autoimmune disorder def postmarketing x
Neoplasm malignant def postmarketing x x
Skin cancer def postmarketing x x
Cerebellar syndrome def postmarketing x x x x x x x
Transient ischaemic attack def postmarketing x x x x x x x
Cholelithiasis def postmarketing x x x x x x x
Coma def postmarketing x x x x x x x x
Confusional state def postmarketing x x x x x x x x
Constipation def postmarketing x x x x x x x
Cystitis def postmarketing x x x x x x x
Cyst def postmarketing x
Cytopenia def postmarketing x x x x x x
Dysphagia def postmarketing x x x x x x x
Dehydration def postmarketing x x x x x x x
Dysuria def postmarketing x x x x x x x
Effusion def postmarketing x x x x x x x
Toxic epidermal necrolysis def postmarketing x x x
Epistaxis def postmarketing x x x x x x x
Erythema multiforme def postmarketing x x
Oesophagitis def postmarketing x x x x x x x
Eye disorder def postmarketing x
Fibrosis def postmarketing x x x x x x x
Flank pain def postmarketing x x x x x x x
Gastrointestinal disorder def postmarketing x
Gastrointestinal haemorrhage def postmarketing x x x x x x x x x
Cardiac disorder def postmarketing x
Cardiac failure def postmarketing x x x x x x x x x
Cardiac failure congestive def postmarketing x x x x x x x
Haematuria def postmarketing x x x x x x x x x x
Factor VIII deficiency def postmarketing x x x
Haemoptysis def postmarketing x x x x x x x
Haemorrhage def postmarketing x x x x x x x x x
Herpes zoster def postmarketing x x x x
Hyperglycaemia def postmarketing x x x x x x x
Hyperkalaemia def postmarketing x x x x x x x x
Hypersensitivity def postmarketing x x x x x x x
Hypocalcaemia def postmarketing x x x x x x x x
Immune system disorder def postmarketing x
Infarction def postmarketing x x x x x x x
Acute myeloid leukaemia def postmarketing x x x
Myeloid leukaemia def postmarketing x x x
Progressive multifocal leukoencephalopathy def postmarketing x x x x x x
Lymphoproliferative disorder def postmarketing x x x x
Mediastinal disorder def postmarketing x
Myelodysplastic syndrome def postmarketing x x x x
Myocardial infarction def postmarketing x x x x x x x
Neoplasm def postmarketing x x x x x x x x x x
Nervous system disorder def postmarketing x
Neuritis def postmarketing x x x x
Neutropenia def postmarketing x x x x x x x x
Opportunistic infection def postmarketing x x x x x x x x
Optic nerve disorder def postmarketing x x x x
Optic neuritis def postmarketing x x x x
Osteoporosis def postmarketing x x x x x x x
Pancytopenia def postmarketing x x x x x x
Paraesthesia def postmarketing x x x x x x x
Pemphigus def postmarketing x x x
Pericardial effusion def postmarketing x x x x x x x
Neuropathy peripheral def postmarketing x x x x x x x x
Pharyngitis def postmarketing x x x x x x x
Phlebitis def postmarketing x x x x x x x
Polyp def postmarketing x
Proteinuria def postmarketing x x x x x x x
Pruritus def postmarketing x x x x x x x
Pulmonary fibrosis def postmarketing x x x x x x
Purpura def postmarketing x x x
Renal failure def postmarketing x x x x x x x x x x
Acute respiratory distress syndrome def postmarketing x x x x x x
Seborrhoeic dermatitis def postmarketing x x x x x x x
Seizures def postmarketing x x x
Stomatitis def postmarketing x x x x x x x x x x
Cerebrovascular accident def postmarketing x x x x x x x
Tachycardia def postmarketing x x x x x x x
Supraventricular tachycardia def postmarketing x x x x x x x
Thrombocytopenia def postmarketing x x x x x x x x
Thrombosis def postmarketing x x x x x x x
Tumour lysis syndrome def postmarketing x x x x x x x x x
Erythema def postmarketing x x
Venous thrombosis def postmarketing x x x x x x
Viral infection def postmarketing x x
Vomiting def postmarketing x x x x x x x x x x
Chills def postmarketing x x x x x x x x x x
Hepatic failure def postmarketing x x x x x x x
Agitation def postmarketing x x x x x x x x
Hyperphosphataemia def postmarketing x x x x x x x x
Cystitis haemorrhagic postmarketing x x x x x x
Hepatic function abnormal postmarketing x x x x x x x
Deep vein thrombosis def postmarketing x x x x x x
Crystalluria postmarketing x x x x x x x x
Urate crystalluria postmarketing x x x x x x x x
Necrolysis epidermal postmarketing x x x
Pulmonary haemorrhage def postmarketing x x x x x x
Kidney function abnormal postmarketing x x x x x x x
Liver function test abnormal postmarketing x x x x x x x
Bone marrow depression def postmarketing x x x x x x
Urinary hesitation postmarketing x x x x x x x
Metabolic acidosis def postmarketing x x x x x x x x
Malaise def postmarketing x x x x x x x x x x
Myalgia def postmarketing x x x x x x x
Lung infiltration postmarketing x x x x x x x
Renal function test abnormal postmarketing x x x x x x x
Hypoxia def postmarketing x x x x x x x
Autoimmune thrombocytopenia postmarketing x x
Aplasia postmarketing x x x x x x
Hepatobiliary disease def postmarketing x
Leukoencephalopathy def postmarketing x x x x x
Solid tumour def postmarketing x x x x x x x x
Mucosal inflammation def postmarketing x x x x x x x x x
Neuropathy def postmarketing x x x x x x x x
Blindness def postmarketing x x x x
Respiratory distress def postmarketing x x x x x x
Visual disturbance postmarketing x x x x x x x x x x
Dissecting aortic aneurysm, thoracic postmarketing x
Urate postmarketing x x x x x x x x
Hyperuricaemia def postmarketing x x x x x x x x
Infestation NOS postmarketing x
Sleep disorder def postmarketing x x x x x x x
Myelosuppression def postmarketing x x x x x x x x
Thrombocytopenic purpura def postmarketing x x x
Pulmonary toxicity postmarketing x x x x x x
Acquired haemophilia postmarketing x x x
Respiratory failure def postmarketing x x x x x x
Skin toxicity postmarketing x x x x x x x x
Death postmarketing x x x x x x
Hearing impaired def postmarketing x x x x x x x x
Cytolysis def postmarketing x x x x x x x x x x
Leukopenia def x x
Myelofibrosis def x x x x x
Numbness def x
Fever chills x x x x x x
Haemoglobin decreased def x x x x x
Wrist drop x
Evans syndrome def
Platelet count decreased x x x x x
Neutrophil count decreased def x x x x x
Lung infection def x
Absolute neutrophil count decreased x x x x x
Cerebral haemorrhage def
Indication Labels
Chronic lymphocytic leukaemia def x x x x x x x x x
Chronic lymphocytic leukaemia refractory def x
Leukaemia def x x x x x x x x x x
Lymphocytic leukaemia def x x x x x x x x x
Lymphoma def x x
Renal impairment def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L01BB05

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. FLUDARABINE PHOSPHATE / FLUDARA : 74 side effects (Health Canada)
  2. FLUDARABINE PHOSPHATE / FLUDARABINE PHOSPHATE FOR INJECTION : 75 side effects (Health Canada)
  3. FLUDARABINE : 78 side effects (FDA XML label)
  4. FLUDARABINE : 80 side effects (FDA XML label)
  5. FLUDARABINE : 96 side effects (FDA XML label)
  6. fludarabine / Fludara : 121 side effects (FDA CDER)
  7. Fludarabine : 126 side effects (FDA XML label)
  8. Fludarabine : 128 side effects (FDA XML label)
  9. Fludarabine : 150 side effects (FDA XML label)
  10. fludarabine : 150 side effects (FDA XML label)